Noninvasive and localized blood-brain barrier disruption using focused ultrasound can be achieved at short pulse lengths and low pulse repetition frequencies

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 2, 2011, Pages 725-737

  Choi, James J ^a   Selert, Kirsten ^a   Gao, Zimeng ^a   Samiotaki, Gesthimani ^a   Baseri, Babak ^a   Konofagou, Elisa E ^a,b  

^a Columbia University ^*  (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

blood brain barrier; brain drug delivery; dextran; focused ultrasound; microbubbles

Indexed keywords

DEXTRAN;

ACOUSTICS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN REGION; CONCENTRATION (PARAMETERS); FLUORESCENCE ANALYSIS; LEFT HEMISPHERE; MALE; MICROBUBBLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PULSE RATE; QUALITATIVE ANALYSIS; ULTRASOUND;

ANIMALS; BLOOD-AQUEOUS BARRIER; CHEMISTRY, PHARMACEUTICAL; DEXTRANS; FLUORESCENT DYES; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; STEREOTAXIC TECHNIQUES; TIME FACTORS; ULTRASONICS;

EID: 79551632443     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2010.155     Document Type: Article

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