-
1
-
-
84945206498
-
PCR array and protein array studies demonstrate that IL-1β (interleukin-1β) stimulates the expression and secretion of multiple cytokines and chemokines in human adipocytes
-
Alomar, S.Y., Zaibi, M.S., Kępczyńska, M.A., Gentili, A., Alkhuriji, A., Mansour, L., Dar, J.A., Trayhurn, P., PCR array and protein array studies demonstrate that IL-1β (interleukin-1β) stimulates the expression and secretion of multiple cytokines and chemokines in human adipocytes. Arch. Physiol. Biochem. 121 (2015), 187–193.
-
(2015)
Arch. Physiol. Biochem.
, vol.121
, pp. 187-193
-
-
Alomar, S.Y.1
Zaibi, M.S.2
Kępczyńska, M.A.3
Gentili, A.4
Alkhuriji, A.5
Mansour, L.6
Dar, J.A.7
Trayhurn, P.8
-
2
-
-
36549040859
-
The selectivity of protein kinase inhibitors: a further update
-
Bain, J., Plater, L., Elliott, M., Shpiro, N., Hastie, C.J., McLauchlan, H., Klevernic, I., Arthur, J.S., Alessi, D.R., Cohen, P., The selectivity of protein kinase inhibitors: a further update. Biochem. J. 408 (2007), 297–315.
-
(2007)
Biochem. J.
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
Klevernic, I.7
Arthur, J.S.8
Alessi, D.R.9
Cohen, P.10
-
3
-
-
73449087698
-
AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase
-
Benziane, B., Björnholm, M., Lantier, L., Viollet, B., Zierath, J.R., Chibalin, A.V., AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase. Am. J. Physiol. Cell. Physiol. 297 (2009), C1554–C1566.
-
(2009)
Am. J. Physiol. Cell. Physiol.
, vol.297
, pp. C1554-C1566
-
-
Benziane, B.1
Björnholm, M.2
Lantier, L.3
Viollet, B.4
Zierath, J.R.5
Chibalin, A.V.6
-
4
-
-
79958078455
-
Nitric oxide-induced activation of the AMP-activated protein kinase α2 subunit attenuates IκB kinase activity and inflammatory responses in endothelial cells
-
Bess, E., Fisslthaler, B., Frömel, T., Fleming, I., Nitric oxide-induced activation of the AMP-activated protein kinase α2 subunit attenuates IκB kinase activity and inflammatory responses in endothelial cells. PLoS One, 6, 2011, e20848.
-
(2011)
PLoS One
, vol.6
, pp. e20848
-
-
Bess, E.1
Fisslthaler, B.2
Frömel, T.3
Fleming, I.4
-
5
-
-
84872401752
-
Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation
-
Bijland, S., Mancini, S.J., Salt, I.P., Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation. Clin. Sci. (Lond) 124 (2013), 491–507.
-
(2013)
Clin. Sci. (Lond)
, vol.124
, pp. 491-507
-
-
Bijland, S.1
Mancini, S.J.2
Salt, I.P.3
-
6
-
-
79959705713
-
AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study
-
Boyle, J.G., Logan, P.J., Jones, G.C., Small, M., Sattar, N., Connell, J.M., Cleland, S.J., Salt, I.P., AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study. Diabetologia 54 (2011), 1799–1809.
-
(2011)
Diabetologia
, vol.54
, pp. 1799-1809
-
-
Boyle, J.G.1
Logan, P.J.2
Jones, G.C.3
Small, M.4
Sattar, N.5
Connell, J.M.6
Cleland, S.J.7
Salt, I.P.8
-
7
-
-
84929875491
-
Regulation of tumour necrosis factor signalling: live or let die
-
Brenner, D., Blaser, H., Mak, T.W., Regulation of tumour necrosis factor signalling: live or let die. Nat. Rev. Immunol. 15 (2015), 362–374.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 362-374
-
-
Brenner, D.1
Blaser, H.2
Mak, T.W.3
-
8
-
-
84889240278
-
Connection between cardiac vascular permeability, myocardial edema, and inflammation during sepsis: role of the α1AMP-activated protein kinase isoform
-
Castanares-Zapatero, D., Bouleti, C., Sommereyns, C., Gerber, B., Lecut, C., Mathivet, T., Horckmans, M., Communi, D., Foretz, M., Vanoverschelde, J.L., Germain, S., Bertrand, L., Laterre, P.F., Oury, C., Viollet, B., Horman, S., Beauloye, C., Connection between cardiac vascular permeability, myocardial edema, and inflammation during sepsis: role of the α1AMP-activated protein kinase isoform. Crit. Care. Med. 41 (2013), e411–e422.
-
(2013)
Crit. Care. Med.
, vol.41
, pp. e411-e422
-
-
Castanares-Zapatero, D.1
Bouleti, C.2
Sommereyns, C.3
Gerber, B.4
Lecut, C.5
Mathivet, T.6
Horckmans, M.7
Communi, D.8
Foretz, M.9
Vanoverschelde, J.L.10
Germain, S.11
Bertrand, L.12
Laterre, P.F.13
Oury, C.14
Viollet, B.15
Horman, S.16
Beauloye, C.17
-
9
-
-
84946911785
-
Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK
-
Chen, Y., Xu, X., Zhang, Y., Liu, K., Huang, F., Liu, B., Kou, J., Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK. J. Steroid Biochem. Mol. Biol. 155 (2016), 155–165.
-
(2016)
J. Steroid Biochem. Mol. Biol.
, vol.155
, pp. 155-165
-
-
Chen, Y.1
Xu, X.2
Zhang, Y.3
Liu, K.4
Huang, F.5
Liu, B.6
Kou, J.7
-
10
-
-
84901807090
-
The TLR and IL-1 signalling network at a glance
-
Cohen, P., The TLR and IL-1 signalling network at a glance. J. Cell. Sci. 127 (2014), 2383–2390.
-
(2014)
J. Cell. Sci.
, vol.127
, pp. 2383-2390
-
-
Cohen, P.1
-
11
-
-
84903273250
-
AMPK activation: a therapeutic target for type 2 diabetes?
-
Coughlan, K.A., Valentine, R.J., Ruderman, N.B., Saha, A.K., AMPK activation: a therapeutic target for type 2 diabetes?. Diabetes Metab. Syndr. Obes. 7 (2014), 241–253.
-
(2014)
Diabetes Metab. Syndr. Obes.
, vol.7
, pp. 241-253
-
-
Coughlan, K.A.1
Valentine, R.J.2
Ruderman, N.B.3
Saha, A.K.4
-
12
-
-
77149134285
-
Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo
-
Dong, Y., Zhang, M., Liang, B., Xie, Z., Zhao, Z., Asfa, S., Choi, H.C., Zou, M.H., Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo. Circulation 121 (2010), 792–803.
-
(2010)
Circulation
, vol.121
, pp. 792-803
-
-
Dong, Y.1
Zhang, M.2
Liang, B.3
Xie, Z.4
Zhao, Z.5
Asfa, S.6
Choi, H.C.7
Zou, M.H.8
-
13
-
-
57549088860
-
Inhibition of tumour necrosis factor-alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase
-
Ewart, M.A., Kohlhaas, C.F., Salt, I.P., Inhibition of tumour necrosis factor-alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase. Arterioscler. Thromb. Vasc. Biol. 28 (2008), 2255–2257.
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, pp. 2255-2257
-
-
Ewart, M.A.1
Kohlhaas, C.F.2
Salt, I.P.3
-
14
-
-
78049431237
-
The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling
-
Flannery, S., Bowie, A.G., The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling. Biochem. Pharmacol. 80 (2010), 1981–1991.
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 1981-1991
-
-
Flannery, S.1
Bowie, A.G.2
-
15
-
-
77954933558
-
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
-
Foretz, M., Hébrard, S., Leclerc, J., Zarrinpashneh, E., Soty, M., Mithieux, G., Sakamoto, K., Andreelli, F., Viollet, B., Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J. Clin. Investig. 120 (2010), 2355–2369.
-
(2010)
J. Clin. Investig.
, vol.120
, pp. 2355-2369
-
-
Foretz, M.1
Hébrard, S.2
Leclerc, J.3
Zarrinpashneh, E.4
Soty, M.5
Mithieux, G.6
Sakamoto, K.7
Andreelli, F.8
Viollet, B.9
-
16
-
-
84941730257
-
New nordic diet-induced weight loss is accompanied by changes in metabolism and AMPK signaling in adipose tissue
-
Fritzen, A.M., Lundsgaard, A.M., Jordy, A.B., Poulsen, S.K., Stender, S., Pilegaard, H., Astrup, A., Larsen, T.M., Wojtaszewski, J.F., Richter, E.A., Kiens, B., New nordic diet-induced weight loss is accompanied by changes in metabolism and AMPK signaling in adipose tissue. J. Clin. Endocrinol. Metab. 100 (2015), 3509–3519.
-
(2015)
J. Clin. Endocrinol. Metab.
, vol.100
, pp. 3509-3519
-
-
Fritzen, A.M.1
Lundsgaard, A.M.2
Jordy, A.B.3
Poulsen, S.K.4
Stender, S.5
Pilegaard, H.6
Astrup, A.7
Larsen, T.M.8
Wojtaszewski, J.F.9
Richter, E.A.10
Kiens, B.11
-
17
-
-
84055190798
-
Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity
-
Galic, S., Fullerton, M.D., Schertzer, J.D., Sikkema, S., Marcinko, K., Walkley, C.R., Izon, D., Honeyman, J., Chen, Z.P., van Denderen, B.J., Kemp, B.E., Steinberg, G.R., Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity. J. Clin. Investig. 121 (2011), 4903–4915.
-
(2011)
J. Clin. Investig.
, vol.121
, pp. 4903-4915
-
-
Galic, S.1
Fullerton, M.D.2
Schertzer, J.D.3
Sikkema, S.4
Marcinko, K.5
Walkley, C.R.6
Izon, D.7
Honeyman, J.8
Chen, Z.P.9
van Denderen, B.J.10
Kemp, B.E.11
Steinberg, G.R.12
-
18
-
-
74149083791
-
AMPK-independent down-regulation of cFLIP and sensitization to TRAIL-induced apoptosis by AMPK activators
-
García-García, C., Fumarola, C., Navaratnam, N., Carling, D., López-Rivas, A., AMPK-independent down-regulation of cFLIP and sensitization to TRAIL-induced apoptosis by AMPK activators. Biochem. Pharmacol. 79 (2010), 853–863.
-
(2010)
Biochem. Pharmacol.
, vol.79
, pp. 853-863
-
-
García-García, C.1
Fumarola, C.2
Navaratnam, N.3
Carling, D.4
López-Rivas, A.5
-
19
-
-
78650964142
-
Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans
-
Gauthier, M.S., O'Brien, E.L., Bigornia, S., Mott, M., Cacicedo, J.M., Xu, X.J., Gokce, N., Apovian, C., Ruderman, N., Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans. Biochem. Biophys. Res. Commun. 404 (2011), 382–387.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.404
, pp. 382-387
-
-
Gauthier, M.S.1
O'Brien, E.L.2
Bigornia, S.3
Mott, M.4
Cacicedo, J.M.5
Xu, X.J.6
Gokce, N.7
Apovian, C.8
Ruderman, N.9
-
20
-
-
36348998521
-
Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase
-
Göransson, O., McBride, A., Hawley, S.A., Ross, F.A., Shpiro, N., Foretz, M., Viollet, B., Hardie, D.G., Sakamoto, K., Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase. J. Biol. Chem. 282 (2007), 32549–32560.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32549-32560
-
-
Göransson, O.1
McBride, A.2
Hawley, S.A.3
Ross, F.A.4
Shpiro, N.5
Foretz, M.6
Viollet, B.7
Hardie, D.G.8
Sakamoto, K.9
-
21
-
-
79953221811
-
Counter-modulation of fatty acid-induced pro-inflammatory nuclear factor κB signalling in rat skeletal muscle cells by AMP-activated protein kinase
-
Green, C.J., Macrae, K., Fogarty, S., Hardie, D.G., Sakamoto, K., Hundal, H.S., Counter-modulation of fatty acid-induced pro-inflammatory nuclear factor κB signalling in rat skeletal muscle cells by AMP-activated protein kinase. Biochem. J. 435 (2011), 463–474.
-
(2011)
Biochem. J.
, vol.435
, pp. 463-474
-
-
Green, C.J.1
Macrae, K.2
Fogarty, S.3
Hardie, D.G.4
Sakamoto, K.5
Hundal, H.S.6
-
22
-
-
33745218224
-
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase-independent effect on glucokinase translocation
-
Guigas, B., Bertrand, L., Taleux, N., Foretz, M., Wiernsperger, N., Vertommen, D., Andreelli, F., Viollet, B., Hue, L., 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase-independent effect on glucokinase translocation. Diabetes 55 (2006), 865–874.
-
(2006)
Diabetes
, vol.55
, pp. 865-874
-
-
Guigas, B.1
Bertrand, L.2
Taleux, N.3
Foretz, M.4
Wiernsperger, N.5
Vertommen, D.6
Andreelli, F.7
Viollet, B.8
Hue, L.9
-
23
-
-
0034805751
-
The effects of AICAR on adipocyte differentiation of 3T3-L1 cells
-
Habinowski, S.A., Witters, L.A., The effects of AICAR on adipocyte differentiation of 3T3-L1 cells. Biochem. Biophys. Res. Commun. 286 (2001), 1195–1207.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.286
, pp. 1195-1207
-
-
Habinowski, S.A.1
Witters, L.A.2
-
24
-
-
77956410464
-
Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation
-
Hawley, S.A., Ross, F.A., Chevtzoff, C., Green, K.A., Evans, A., Fogarty, S., Towler, M.C., Brown, L.J., Ogunbayo, O.A., Evans, A.M., Hardie, D.G., Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation. Cell Metab. 11 (2010), 554–565.
-
(2010)
Cell Metab.
, vol.11
, pp. 554-565
-
-
Hawley, S.A.1
Ross, F.A.2
Chevtzoff, C.3
Green, K.A.4
Evans, A.5
Fogarty, S.6
Towler, M.C.7
Brown, L.J.8
Ogunbayo, O.A.9
Evans, A.M.10
Hardie, D.G.11
-
25
-
-
65649108647
-
Berberine suppresses proinflammatory responses through AMPK activation in macrophages
-
Jeong, H.W., Hsu, K.C., Lee, J.W., Ham, M., Huh, J.Y., Shin, H.J., Kim, W.S., Kim, J.B., Berberine suppresses proinflammatory responses through AMPK activation in macrophages. Am. J. Physiol. Endocrinol. Metab. 296 (2009), E955–E964.
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.296
, pp. E955-E964
-
-
Jeong, H.W.1
Hsu, K.C.2
Lee, J.W.3
Ham, M.4
Huh, J.Y.5
Shin, H.J.6
Kim, W.S.7
Kim, J.B.8
-
26
-
-
0345832116
-
Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle
-
Jørgensen, S.B., Viollet, B., Andreelli, F., Frøsig, C., Birk, J.B., Schjerling, P., Vaulont, S., Richter, E.A., Wojtaszewski, J.F., Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle. J. Biol. Chem. 279 (2004), 1070–1079.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 1070-1079
-
-
Jørgensen, S.B.1
Viollet, B.2
Andreelli, F.3
Frøsig, C.4
Birk, J.B.5
Schjerling, P.6
Vaulont, S.7
Richter, E.A.8
Wojtaszewski, J.F.9
-
27
-
-
80054982173
-
Compound C independent of AMPK inhibits ICAM-1 and VCAM-1 expression in inflammatory stimulants-activated endothelial cells in vitro and in vivo
-
Kim, Y.M., Kim, M.Y., Kim, H.J., Roh, G.S., Ko, G.H., Seo, H.G., Lee, J.H., Chang, K.C., Compound C independent of AMPK inhibits ICAM-1 and VCAM-1 expression in inflammatory stimulants-activated endothelial cells in vitro and in vivo. Atherosclerosis 219 (2011), 57–64.
-
(2011)
Atherosclerosis
, vol.219
, pp. 57-64
-
-
Kim, Y.M.1
Kim, M.Y.2
Kim, H.J.3
Roh, G.S.4
Ko, G.H.5
Seo, H.G.6
Lee, J.H.7
Chang, K.C.8
-
28
-
-
84862817442
-
Metformin ameliorates IL-6-induced hepatic insulin resistance via induction of orphan nuclear receptor small heterodimer partner (SHP) in mouse models
-
Kim, Y.D., Kim, Y.H., Cho, Y.M., Kim, D.K., Ahn, S.W., Lee, J.M., Chanda, D., Shong, M., Lee, C.H., Choi, H.S., Metformin ameliorates IL-6-induced hepatic insulin resistance via induction of orphan nuclear receptor small heterodimer partner (SHP) in mouse models. Diabetologia 55 (2012), 1482–1494.
-
(2012)
Diabetologia
, vol.55
, pp. 1482-1494
-
-
Kim, Y.D.1
Kim, Y.H.2
Cho, Y.M.3
Kim, D.K.4
Ahn, S.W.5
Lee, J.M.6
Chanda, D.7
Shong, M.8
Lee, C.H.9
Choi, H.S.10
-
29
-
-
84915751694
-
Adipocyte-specific IKKβ signaling suppresses adipose tissue inflammation through an IL-13-dependent paracrine feedback pathway
-
Kwon, H., Laurent, S., Tang, Y., Zong, H., Vemulapalli, P., Pessin, J.E., Adipocyte-specific IKKβ signaling suppresses adipose tissue inflammation through an IL-13-dependent paracrine feedback pathway. Cell Rep. 9 (2014), 1574–1583.
-
(2014)
Cell Rep.
, vol.9
, pp. 1574-1583
-
-
Kwon, H.1
Laurent, S.2
Tang, Y.3
Zong, H.4
Vemulapalli, P.5
Pessin, J.E.6
-
30
-
-
33745840203
-
5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments
-
Laderoute, K.R., Amin, K., Calaoagan, J.M., Knapp, M., Le, T., Orduna, J., Foretz, M., Viollet, B., 5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol. Cell. Biol. 26 (2006), 5336–5347.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 5336-5347
-
-
Laderoute, K.R.1
Amin, K.2
Calaoagan, J.M.3
Knapp, M.4
Le, T.5
Orduna, J.6
Foretz, M.7
Viollet, B.8
-
31
-
-
74949113508
-
The relationship between adipokines, metabolic parameters and insulin resistance in patients with metabolic syndrome and type 2 diabetes
-
Lee, J.M., Kim, S.R., Yoo, S.J., Hong, O.K., Son, H.S., Chang, S.A., The relationship between adipokines, metabolic parameters and insulin resistance in patients with metabolic syndrome and type 2 diabetes. J. Int. Med. Res. 37 (2009), 1803–1812.
-
(2009)
J. Int. Med. Res.
, vol.37
, pp. 1803-1812
-
-
Lee, J.M.1
Kim, S.R.2
Yoo, S.J.3
Hong, O.K.4
Son, H.S.5
Chang, S.A.6
-
32
-
-
1642335469
-
AICAR stimulates adiponectin and inhibits cytokines in adipose tissue
-
Lihn, A.S., Jessen, N., Pedersen, S.B., Lund, S., Richelsen, B., AICAR stimulates adiponectin and inhibits cytokines in adipose tissue. Biochem. Biophys. Res. Commun. 316 (2004), 853–858.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.316
, pp. 853-858
-
-
Lihn, A.S.1
Jessen, N.2
Pedersen, S.B.3
Lund, S.4
Richelsen, B.5
-
33
-
-
49349106929
-
The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells
-
Lihn, A.S., Pedersen, S.B., Lund, S., Richelsen, B., The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells. Mol. Cell. Endocrinol. 292 (2008), 36–41.
-
(2008)
Mol. Cell. Endocrinol.
, vol.292
, pp. 36-41
-
-
Lihn, A.S.1
Pedersen, S.B.2
Lund, S.3
Richelsen, B.4
-
34
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng, C.N., Bodzin, J.L., Saltiel, A.R., Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Investig. 117 (2007), 175–184.
-
(2007)
J. Clin. Investig.
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
35
-
-
84871848035
-
AMP-activated protein kinase restricts IFN-γ signaling
-
Meares, G.P., Qin, H., Liu, Y., Holdbrooks, A.T., Benveniste, E.N., AMP-activated protein kinase restricts IFN-γ signaling. J. Immunol. 190 (2013), 372–380.
-
(2013)
J. Immunol.
, vol.190
, pp. 372-380
-
-
Meares, G.P.1
Qin, H.2
Liu, Y.3
Holdbrooks, A.T.4
Benveniste, E.N.5
-
36
-
-
84862819570
-
120 but reduces MCP-1 release in mature 3T3-L1 adipocytes: possible regulatory mechanism through endogenous ER stress and AMPK-related pathways
-
120 but reduces MCP-1 release in mature 3T3-L1 adipocytes: possible regulatory mechanism through endogenous ER stress and AMPK-related pathways. Biochem. Biophys. Res. Commun. 419 (2012), 200–205.
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.419
, pp. 200-205
-
-
Miyokawa-Gorin, K.1
Takahashi, K.2
Handa, K.3
Kitahara, A.4
Sumitani, Y.5
Katsuta, H.6
Tanaka, T.7
Nishida, S.8
Yoshimoto, K.9
Ohno, H.10
Ishida, H.11
-
37
-
-
46749127292
-
A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism
-
Moreno, D., Knecht, E., Viollet, B., Sanz, P., A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism. FEBS Lett. 582 (2008), 2650–2654.
-
(2008)
FEBS Lett.
, vol.582
, pp. 2650-2654
-
-
Moreno, D.1
Knecht, E.2
Viollet, B.3
Sanz, P.4
-
38
-
-
84992374677
-
Lack of adipocyte AMPK exacerbates insulin resistance and hepatic steatosis through brown and beige adipose tissue function
-
Mottillo, E.P., Desjardins, E.M., Crane, J.D., Smith, B.K., Green, A.E., Ducommun, S., Henriksen, T.I., Rebalka, I.A., Razi, A., Sakamoto, K., Scheele, C., Kemp, B.E., Hawke, T.J., Ortega, J., Granneman, J.G., Steinberg, G.R., Lack of adipocyte AMPK exacerbates insulin resistance and hepatic steatosis through brown and beige adipose tissue function. Cell Metab. 24 (2016), 118–129.
-
(2016)
Cell Metab.
, vol.24
, pp. 118-129
-
-
Mottillo, E.P.1
Desjardins, E.M.2
Crane, J.D.3
Smith, B.K.4
Green, A.E.5
Ducommun, S.6
Henriksen, T.I.7
Rebalka, I.A.8
Razi, A.9
Sakamoto, K.10
Scheele, C.11
Kemp, B.E.12
Hawke, T.J.13
Ortega, J.14
Granneman, J.G.15
Steinberg, G.R.16
-
39
-
-
84878933932
-
Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes
-
Nerstedt, A., Cansby, E., Amrutkar, M., Smith, U., Mahlapuu, M., Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes. Mol. Cell. Endocrinol. 375 (2013), 68–78.
-
(2013)
Mol. Cell. Endocrinol.
, vol.375
, pp. 68-78
-
-
Nerstedt, A.1
Cansby, E.2
Amrutkar, M.3
Smith, U.4
Mahlapuu, M.5
-
40
-
-
84904558110
-
IL-6 in diabetes and cardiovascular complications
-
Qu, D., Liu, J., Lau, C.W., Huang, Y., IL-6 in diabetes and cardiovascular complications. Br. J. Pharmacol. 171 (2014), 3595–3603.
-
(2014)
Br. J. Pharmacol.
, vol.171
, pp. 3595-3603
-
-
Qu, D.1
Liu, J.2
Lau, C.W.3
Huang, Y.4
-
41
-
-
84923346612
-
Cholesteryl ester-transfer protein inhibitors stimulate aldosterone biosynthesis in adipocytes through nox-dependent processes
-
Rios, F.J., Neves, K.B., Nguyen Dinh Cat, A., Even, S., Palacios, R., Montezano, A.C., Touyz, R.M., Cholesteryl ester-transfer protein inhibitors stimulate aldosterone biosynthesis in adipocytes through nox-dependent processes. J. Pharmacol. Exp. Ther. 353 (2015), 27–34.
-
(2015)
J. Pharmacol. Exp. Ther.
, vol.353
, pp. 27-34
-
-
Rios, F.J.1
Neves, K.B.2
Nguyen Dinh Cat, A.3
Even, S.4
Palacios, R.5
Montezano, A.C.6
Touyz, R.M.7
-
42
-
-
0037428279
-
Efficient adenovirus transduction of 3T3-L1 adipocytes stably expressing coxsackie-adenovirus receptor
-
Ross, S.A., Song, X., Burney, M.W., Kasai, Y., Orlicky, D.J., Efficient adenovirus transduction of 3T3-L1 adipocytes stably expressing coxsackie-adenovirus receptor. Biochem. Biophys. Res. Commun. 302 (2003), 354–358.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.302
, pp. 354-358
-
-
Ross, S.A.1
Song, X.2
Burney, M.W.3
Kasai, Y.4
Orlicky, D.J.5
-
43
-
-
0242580711
-
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
-
Rotter, V., Nagaev, I., Smith, U., Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J. Biol. Chem. 278 (2003), 45777–45784.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45777-45784
-
-
Rotter, V.1
Nagaev, I.2
Smith, U.3
-
44
-
-
84994908860
-
Rapid AMP-activated protein kinase (AMPK) phosphorylation of Janus kinase 1 (JAK1) links energy sensing to anti-inflammatory signalling
-
Rutherford, C., Speirs, C., Williams, J.J., Ewart, M.-A., Mancini, S.J., Hawley, S.A., Delles, C., Viollet, B., Costa-Pereira, A.P., Baillie, G.S., Salt, I.P., Palmer, T.M., Rapid AMP-activated protein kinase (AMPK) phosphorylation of Janus kinase 1 (JAK1) links energy sensing to anti-inflammatory signalling. Sci. Signal., 9, 2016, ra109.
-
(2016)
Sci. Signal.
, vol.9
, pp. ra109
-
-
Rutherford, C.1
Speirs, C.2
Williams, J.J.3
Ewart, M.-A.4
Mancini, S.J.5
Hawley, S.A.6
Delles, C.7
Viollet, B.8
Costa-Pereira, A.P.9
Baillie, G.S.10
Salt, I.P.11
Palmer, T.M.12
-
45
-
-
58849115949
-
Adenosine 5’-monophosphate-activated protein kinase promotes macrophage polarisation to an anti-inflammatory functional phenotype
-
Sag, D., Carling, D., Stout, R.D., Suttles, J., Adenosine 5’-monophosphate-activated protein kinase promotes macrophage polarisation to an anti-inflammatory functional phenotype. J. Immunol. 181 (2008), 8633–8641.
-
(2008)
J. Immunol.
, vol.181
, pp. 8633-8641
-
-
Sag, D.1
Carling, D.2
Stout, R.D.3
Suttles, J.4
-
46
-
-
84863700565
-
Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation
-
Salt, I.P., Palmer, T.M., Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation. Expert Opin. Investig. Drugs 21 (2012), 1155–1167.
-
(2012)
Expert Opin. Investig. Drugs
, vol.21
, pp. 1155-1167
-
-
Salt, I.P.1
Palmer, T.M.2
-
47
-
-
56049112796
-
Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes
-
Scott, J.W., van Denderen, B.J., Jorgensen, S.B., Honeyman, J.E., Steinberg, G.R., Oakhill, J.S., Iseli, T.J., Koay, A., Gooley, P.R., Stapleton, D., Kemp, B.E., Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes. Chem. Biol. 15 (2008), 1220–1230.
-
(2008)
Chem. Biol.
, vol.15
, pp. 1220-1230
-
-
Scott, J.W.1
van Denderen, B.J.2
Jorgensen, S.B.3
Honeyman, J.E.4
Steinberg, G.R.5
Oakhill, J.S.6
Iseli, T.J.7
Koay, A.8
Gooley, P.R.9
Stapleton, D.10
Kemp, B.E.11
-
48
-
-
84880775951
-
Inhibition of the TNF-α-induced serine phosphorylation of IRS-1 at 636/639 by AICAR
-
Shibata, T., Takaguri, A., Ichihara, K., Satoh, K., Inhibition of the TNF-α-induced serine phosphorylation of IRS-1 at 636/639 by AICAR. J. Pharmacol. Sci. 122 (2013), 93–102.
-
(2013)
J. Pharmacol. Sci.
, vol.122
, pp. 93-102
-
-
Shibata, T.1
Takaguri, A.2
Ichihara, K.3
Satoh, K.4
-
49
-
-
84906482561
-
Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1
-
Sun, Y., Li, J., Xiao, N., Wang, M., Kou, J., Qi, L., Huang, F., Liu, B., Liu, K., Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1. Pharmacol. Res. 89 (2014), 19–28.
-
(2014)
Pharmacol. Res.
, vol.89
, pp. 19-28
-
-
Sun, Y.1
Li, J.2
Xiao, N.3
Wang, M.4
Kou, J.5
Qi, L.6
Huang, F.7
Liu, B.8
Liu, K.9
-
50
-
-
45549103859
-
JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro
-
Takahashi, K., Yamaguchi, S., Shimoyama, T., Seki, H., Miyokawa, K., Katsuta, H., Tanaka, T., Yoshimoto, K., Ohno, H., Nagamatsu, S., Ishida, H., JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro. Am. J. Physiol. Endocrinol. Metab. 294 (2008), E898–E909.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.294
, pp. E898-E909
-
-
Takahashi, K.1
Yamaguchi, S.2
Shimoyama, T.3
Seki, H.4
Miyokawa, K.5
Katsuta, H.6
Tanaka, T.7
Yoshimoto, K.8
Ohno, H.9
Nagamatsu, S.10
Ishida, H.11
-
51
-
-
23044483249
-
Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor target genes
-
Thiefes, A., Wolter, S., Mushinski, J.F., Hoffmann, E., Dittrich-Breiholz, O., Graue, N., Dörrie, A., Schneider, H., Wirth, D., Luckow, B., Resch, K., Kracht, M., Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor target genes. J. Biol. Chem. 280 (2005), 27728–27741.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 27728-27741
-
-
Thiefes, A.1
Wolter, S.2
Mushinski, J.F.3
Hoffmann, E.4
Dittrich-Breiholz, O.5
Graue, N.6
Dörrie, A.7
Schneider, H.8
Wirth, D.9
Luckow, B.10
Resch, K.11
Kracht, M.12
-
52
-
-
77954589064
-
AMPK inhibition in health and disease
-
Viollet, B., Horman, S., Leclerc, J., Lantier, L., Foretz, M., Billaud, M., Giri, S., Andreelli, F., AMPK inhibition in health and disease. Crit. Rev. Biochem. Mol. Biol. 45 (2010), 276–295.
-
(2010)
Crit. Rev. Biochem. Mol. Biol.
, vol.45
, pp. 276-295
-
-
Viollet, B.1
Horman, S.2
Leclerc, J.3
Lantier, L.4
Foretz, M.5
Billaud, M.6
Giri, S.7
Andreelli, F.8
-
53
-
-
70350674147
-
Signal transducer and activator of transcription 3 (STAT3) regulates adipocyte differentiation via peroxisome-proliferator-activated receptor gamma (PPARgamma)
-
Wang, D., Zhou, Y., Lei, W., Zhang, K., Shi, J., Hu, Y., Shu, G., Song, J., Signal transducer and activator of transcription 3 (STAT3) regulates adipocyte differentiation via peroxisome-proliferator-activated receptor gamma (PPARgamma). Biol. Cell. 102 (2009), 1–12.
-
(2009)
Biol. Cell.
, vol.102
, pp. 1-12
-
-
Wang, D.1
Zhou, Y.2
Lei, W.3
Zhang, K.4
Shi, J.5
Hu, Y.6
Shu, G.7
Song, J.8
-
54
-
-
77950989801
-
AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes
-
Wang, S., Zhang, M., Liang, B., Xu, J., Xie, Z., Liu, C., Viollet, B., Yan, D., Zou, M.H., AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes. Circ. Res. 106 (2010), 1117–1128.
-
(2010)
Circ. Res.
, vol.106
, pp. 1117-1128
-
-
Wang, S.1
Zhang, M.2
Liang, B.3
Xu, J.4
Xie, Z.5
Liu, C.6
Viollet, B.7
Yan, D.8
Zou, M.H.9
-
55
-
-
84883206493
-
Opposite effects of genistein on the regulation of insulin-mediated glucose homeostasis in adipose tissue
-
Wang, M., Gao, X.J., Zhao, W.W., Zhao, W.J., Jiang, C.H., Huang, F., Kou, J.P., Liu, B.L., Liu, K., Opposite effects of genistein on the regulation of insulin-mediated glucose homeostasis in adipose tissue. Br. J. Pharmacol. 170 (2013), 328–340.
-
(2013)
Br. J. Pharmacol.
, vol.170
, pp. 328-340
-
-
Wang, M.1
Gao, X.J.2
Zhao, W.W.3
Zhao, W.J.4
Jiang, C.H.5
Huang, F.6
Kou, J.P.7
Liu, B.L.8
Liu, K.9
-
56
-
-
0033815967
-
Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase
-
Woods, A., Azzout-Marniche, D., Foretz, M., Stein, S.C., Lemarchand, P., Ferré, P., Foufelle, F., Carling, D., Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol. Cell. Biol. 20 (2000), 6704–6711.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6704-6711
-
-
Woods, A.1
Azzout-Marniche, D.2
Foretz, M.3
Stein, S.C.4
Lemarchand, P.5
Ferré, P.6
Foufelle, F.7
Carling, D.8
-
57
-
-
84940002527
-
Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo
-
Wu, Y., Song, P., Zhang, W., Liu, J., Dai, X., Liu, Z., Lu, Q., Ouyang, C., Xie, Z., Zhao, Z., Zhuo, X., Viollet, B., Foretz, M., Wu, J., Yuan, Z., Zou, M.H., Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo. Nat. Med. 21 (2015), 373–382.
-
(2015)
Nat. Med.
, vol.21
, pp. 373-382
-
-
Wu, Y.1
Song, P.2
Zhang, W.3
Liu, J.4
Dai, X.5
Liu, Z.6
Lu, Q.7
Ouyang, C.8
Xie, Z.9
Zhao, Z.10
Zhuo, X.11
Viollet, B.12
Foretz, M.13
Wu, J.14
Yuan, Z.15
Zou, M.H.16
-
58
-
-
84957075059
-
Improved insulin sensitivity 3 Months after RYGB surgery is associated with increased subcutaneous adipose tissue AMPK activity and decreased oxidative stress
-
Xu, X.J., Apovian, C., Hess, D., Carmine, B., Saha, A., Ruderman, N., Improved insulin sensitivity 3 Months after RYGB surgery is associated with increased subcutaneous adipose tissue AMPK activity and decreased oxidative stress. Diabetes 64 (2015), 3155–3159.
-
(2015)
Diabetes
, vol.64
, pp. 3155-3159
-
-
Xu, X.J.1
Apovian, C.2
Hess, D.3
Carmine, B.4
Saha, A.5
Ruderman, N.6
-
59
-
-
77953517927
-
Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonises fatty acid-induced inflammation through SIRT1
-
Yang, Z., Kahn, B.B., Shi, H., Xue, B.Z., Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonises fatty acid-induced inflammation through SIRT1. J. Biol. Chem. 285 (2010), 19051–19059.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 19051-19059
-
-
Yang, Z.1
Kahn, B.B.2
Shi, H.3
Xue, B.Z.4
-
60
-
-
84953296173
-
AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia
-
Zaha, V.G., Qi, D., Su, K.N., Palmeri, M., Lee, H.Y., Hu, X., Wu, X., Shulman, G.I., Rabinovitch, P.S., Russell, R.R., Young, L.H., AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia. J. Mol. Cell. Cardiol. 91 (2016), 104–113.
-
(2016)
J. Mol. Cell. Cardiol.
, vol.91
, pp. 104-113
-
-
Zaha, V.G.1
Qi, D.2
Su, K.N.3
Palmeri, M.4
Lee, H.Y.5
Hu, X.6
Wu, X.7
Shulman, G.I.8
Rabinovitch, P.S.9
Russell, R.R.10
Young, L.H.11
-
61
-
-
81755174323
-
AMP-activated protein kinase suppresses endothelial cell inflammation through phosphorylation of transcriptional coactivator p300
-
Zhang, Y., Qiu, J., Wang, X., Xia, M., AMP-activated protein kinase suppresses endothelial cell inflammation through phosphorylation of transcriptional coactivator p300. Arterioscler. Thromb. Vasc. Biol. 31 (2011), 2897–2908.
-
(2011)
Arterioscler. Thromb. Vasc. Biol.
, vol.31
, pp. 2897-2908
-
-
Zhang, Y.1
Qiu, J.2
Wang, X.3
Xia, M.4
-
62
-
-
84894254541
-
The total phenolic fraction of Anemarrhena asphodeloides inhibits inflammation and reduces insulin resistance in adipocytes via regulation of AMP-kinase activity
-
Zhao, W., Wang, M., Shao, L., Liao, M., Liu, K., Huang, F., Liu, B., The total phenolic fraction of Anemarrhena asphodeloides inhibits inflammation and reduces insulin resistance in adipocytes via regulation of AMP-kinase activity. Planta. Med. 80 (2014), 146–152.
-
(2014)
Planta. Med.
, vol.80
, pp. 146-152
-
-
Zhao, W.1
Wang, M.2
Shao, L.3
Liao, M.4
Liu, K.5
Huang, F.6
Liu, B.7
|