-
1
-
-
79954632229
-
Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide
-
Dubé, J.J. et al. Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide. Diabetologia 54, 1147-1156 (2011).
-
(2011)
Diabetologia
, vol.54
, pp. 1147-1156
-
-
Dubé, J.J.1
-
2
-
-
0033542401
-
Effect of cigar smoking on the risk of cardiovascular disease, chronic obstructive pulmonary disease, and cancer in men
-
Iribarren, C., Tekawa, I.S., Sidney, S. & Friedman, G.D. Effect of cigar smoking on the risk of cardiovascular disease, chronic obstructive pulmonary disease, and cancer in men. N. Engl. J. Med. 340, 1773-1780 (1999).
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1773-1780
-
-
Iribarren, C.1
Tekawa, I.S.2
Sidney, S.3
Friedman, G.D.4
-
3
-
-
0029787156
-
Long-term use of nicotine gum is associated with hyperinsulinemia and insulin resistance
-
Eliasson, B., Taskinen, M.R. & Smith, U. Long-term use of nicotine gum is associated with hyperinsulinemia and insulin resistance. Circulation 94, 878-881 (1996).
-
(1996)
Circulation
, vol.94
, pp. 878-881
-
-
Eliasson, B.1
Taskinen, M.R.2
Smith, U.3
-
4
-
-
0020093041
-
Smoking and its effects on body weight and the systems of caloric regulation
-
Wack, J.T. & Rodin, J. Smoking and its effects on body weight and the systems of caloric regulation. Am. J. Clin. Nutr. 35, 366-380 (1982).
-
(1982)
Am. J. Clin. Nutr.
, vol.35
, pp. 366-380
-
-
Wack, J.T.1
Rodin, J.2
-
5
-
-
0028851975
-
The infuence of smoking cessation on the prevalence of overweight in the United-States
-
Flegal, K.M., Troiano, R.P., Pamuk, E.R., Kuczmarski, R.J. & Campbell, S.M. The infuence of smoking cessation on the prevalence of overweight in the United-States. N. Engl. J. Med. 333, 1165-1170 (1995).
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 1165-1170
-
-
Flegal, K.M.1
Troiano, R.P.2
Pamuk, E.R.3
Kuczmarski, R.J.4
Campbell, S.M.5
-
6
-
-
0026034372
-
Smoking cessation and severity of weight-gain in a national cohort
-
Williamson, D.F. et al. Smoking cessation and severity of weight-gain in a national cohort. N. Engl. J. Med. 324, 739-745 (1991).
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 739-745
-
-
Williamson, D.F.1
-
7
-
-
84885418407
-
The prevalence, predictors and associated health outcomes of high nicotine dependence using three measures among US smokers
-
Schnoll, R.A., Goren, A., Annunziata, K. & Suaya, J.A. The prevalence, predictors and associated health outcomes of high nicotine dependence using three measures among US smokers. Addiction 108, 1989-2000 (2013).
-
(2013)
Addiction
, vol.108
, pp. 1989-2000
-
-
Schnoll, R.A.1
Goren, A.2
Annunziata, K.3
Suaya, J.A.4
-
8
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
-
Johnson, G.L. & Lapadat, R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298, 1911-1912 (2002).
-
(2002)
Science
, vol.298
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
9
-
-
0242580711
-
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
-
Rotter, V., Nagaev, I. & Smith, U. Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J. Biol. Chem. 278, 45777-45784 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45777-45784
-
-
Rotter, V.1
Nagaev, I.2
Smith, U.3
-
10
-
-
23944475571
-
Roles of mTOR and JNK in serine phosphorylation, translocation, and degradation of IRS-1
-
Hiratani, K. et al. Roles of mTOR and JNK in serine phosphorylation, translocation, and degradation of IRS-1. Biochem. Biophys. Res. Commun. 335, 836-842 (2005).
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.335
, pp. 836-842
-
-
Hiratani, K.1
-
11
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi, J. et al. A central role for JNK in obesity and insulin resistance. Nature 420, 333-336 (2002).
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
-
12
-
-
0041302157
-
JNK: A new therapeutic target for diabetes
-
Bennett, B.L., Satoh, Y. & Lewis, A.J. JNK: a new therapeutic target for diabetes. Curr. Opin. Pharmacol. 3, 420-425 (2003).
-
(2003)
Curr. Opin. Pharmacol.
, vol.3
, pp. 420-425
-
-
Bennett, B.L.1
Satoh, Y.2
Lewis, A.J.3
-
13
-
-
84867358869
-
Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes
-
Fernández-Galilea, M., Perez-Matute, P., Prieto-Hontoria, P.L., Martinez, J.A. & Moreno-Aliaga, M.J. Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes. J. Lipid Res. 53, 2296-2306 (2012).
-
(2012)
J. Lipid Res.
, vol.53
, pp. 2296-2306
-
-
Fernández-Galilea, M.1
Perez-Matute, P.2
Prieto-Hontoria, P.L.3
Martinez, J.A.4
Moreno-Aliaga, M.J.5
-
14
-
-
0031817225
-
Signalling pathways involved in nicotine regulation of apoptosis of human lung cancer cells
-
Heusch, W.L. & Maneckjee, R. Signalling pathways involved in nicotine regulation of apoptosis of human lung cancer cells. Carcinogenesis 19, 551-556 (1998).
-
(1998)
Carcinogenesis
, vol.19
, pp. 551-556
-
-
Heusch, W.L.1
Maneckjee, R.2
-
15
-
-
79952671534
-
Nicotine induces upregulated expression of beta defensin-2 via the p38MAPK pathway in the HaCaT human keratinocyte cell line
-
Nakamura, S. et al. Nicotine induces upregulated expression of beta defensin-2 via the p38MAPK pathway in the HaCaT human keratinocyte cell line. Med. Mol. Morphol. 43, 204-210 (2010).
-
(2010)
Med. Mol. Morphol.
, vol.43
, pp. 204-210
-
-
Nakamura, S.1
-
16
-
-
9144246960
-
Nicotine enhances angiotensin II-induced mitogenic response in vascular smooth muscle cells and fbroblasts
-
Li, J.M. et al. Nicotine enhances angiotensin II-induced mitogenic response in vascular smooth muscle cells and fbroblasts. Arterioscler. Thromb. Vasc. Biol. 24, 80-84 (2004).
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.24
, pp. 80-84
-
-
Li, J.M.1
-
17
-
-
79959956336
-
AMP-activated protein kinase inhibits NF-kappaB signaling and infammation: Impact on healthspan and lifespan
-
Salminen, A., Hyttinen, J.M. & Kaarniranta, K. AMP-activated protein kinase inhibits NF-kappaB signaling and infammation: impact on healthspan and lifespan. J. Mol. Med. 89, 667-676 (2011).
-
(2011)
J. Mol. Med.
, vol.89
, pp. 667-676
-
-
Salminen, A.1
Hyttinen, J.M.2
Kaarniranta, K.3
-
18
-
-
67650914230
-
AMPK in health and disease
-
Steinberg, G.R. & Kemp, B.E. AMPK in health and disease. Physiol. Rev. 89, 1025-1078 (2009).
-
(2009)
Physiol. Rev.
, vol.89
, pp. 1025-1078
-
-
Steinberg, G.R.1
Kemp, B.E.2
-
19
-
-
34848880141
-
Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 adipocytes-A role for oxidant stress
-
An, Z.B. et al. Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 adipocytes-a role for oxidant stress. J. Biol. Chem. 282, 26793-26801 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 26793-26801
-
-
An, Z.B.1
-
20
-
-
84862007631
-
Activation of AMP-activated protein kinase alpha2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo
-
Wang, S. et al. Activation of AMP-activated protein kinase alpha2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo. Nat. Med. 18, 902-910 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 902-910
-
-
Wang, S.1
-
21
-
-
84859557325
-
Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase
-
Martínez de Morentin, P.B. et al. Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. Diabetes 61, 807-817 (2012).
-
(2012)
Diabetes
, vol.61
, pp. 807-817
-
-
Martínez De Morentin, P.B.1
-
22
-
-
0041967223
-
Cigarette smoking and cardiovascular disease: Pathophysiology and implications for treatment
-
Benowitz, N.L. Cigarette smoking and cardiovascular disease: pathophysiology and implications for treatment. Prog. Cardiovasc. Dis. 46, 91-111 (2003).
-
(2003)
Prog. Cardiovasc. Dis.
, vol.46
, pp. 91-111
-
-
Benowitz, N.L.1
-
23
-
-
77952909091
-
The bioequivalent and effect of nicotine formulation gum on smoking cessation
-
Tundulawessa, Y., Yongchaiyud, P., Chutrthong, W. & Tundulawessa, K. The bioequivalent and effect of nicotine formulation gum on smoking cessation. J. Med. Assoc. Thailand (Chotmaihet thangphaet) 93, 574-579 (2010).
-
(2010)
J. Med. Assoc. Thailand (Chotmaihet Thangphaet)
, vol.93
, pp. 574-579
-
-
Tundulawessa, Y.1
Yongchaiyud, P.2
Chutrthong, W.3
Tundulawessa, K.4
-
24
-
-
84890120647
-
Insulin-mediated suppression of lipolysis in adipose tissue and skeletal muscle of obese type 2 diabetic men and men with normal glucose tolerance
-
Jocken, J.W. et al. Insulin-mediated suppression of lipolysis in adipose tissue and skeletal muscle of obese type 2 diabetic men and men with normal glucose tolerance. Diabetologia 56, 2255-2265 (2013).
-
(2013)
Diabetologia
, vol.56
, pp. 2255-2265
-
-
Jocken, J.W.1
-
25
-
-
79958702575
-
Nicotine decreases food intake through activation of POMC neurons
-
Mineur, Y.S. et al. Nicotine decreases food intake through activation of POMC neurons. Science 332, 1330-1332 (2011).
-
(2011)
Science
, vol.332
, pp. 1330-1332
-
-
Mineur, Y.S.1
-
26
-
-
84864657351
-
Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance
-
Pal, D. et al. Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance. Nat. Med. 18, 1279-1285 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 1279-1285
-
-
Pal, D.1
-
27
-
-
84873570184
-
Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance
-
Liew, C.W. et al. Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nat. Med. 19, 217-226 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 217-226
-
-
Liew, C.W.1
-
28
-
-
73849144666
-
Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir
-
Guo, W. et al. Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir. Arterioscler. Thromb. Vasc. Biol. 29, 2028-2032 (2009).
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 2028-2032
-
-
Guo, W.1
-
29
-
-
84858782079
-
AMPK: A nutrient and energy sensor that maintains energy homeostasis
-
Hardie, D.G., Ross, F.A. & Hawley, S.A. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat. Rev. Mol. Cell Biol. 13, 251-262 (2012).
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
30
-
-
84889887123
-
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
-
Fullerton, M.D. et al. Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin. Nat. Med. 19, 1649-1654 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 1649-1654
-
-
Fullerton, M.D.1
-
31
-
-
84879621442
-
AMPK insulin resistance, and the metabolic syndrome
-
Ruderman, N.B., Carling, D., Prentki, M. & Cacicedo, J.M. AMPK, insulin resistance, and the metabolic syndrome. J. Clin. Invest. 123, 2764-2772 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 2764-2772
-
-
Ruderman, N.B.1
Carling, D.2
Prentki, M.3
Cacicedo, J.M.4
-
32
-
-
0035039274
-
AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise
-
Musi, N. et al. AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise. Diabetes 50, 921-927 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 921-927
-
-
Musi, N.1
-
33
-
-
0024516569
-
Phosphorylation of bovine hormone-sensitive lipase by the AMP-activated protein kinase. A possible antilipolytic mechanism
-
Garton, A.J. et al. Phosphorylation of bovine hormone-sensitive lipase by the AMP-activated protein kinase. A possible antilipolytic mechanism. Eur. J Biochemistry 179, 249-254 (1989).
-
(1989)
Eur. J Biochemistry
, vol.179
, pp. 249-254
-
-
Garton, A.J.1
-
34
-
-
21644455008
-
Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes
-
Daval, M. et al. Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes. J. Biol. Chem. 280, 25250-25257 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 25250-25257
-
-
Daval, M.1
-
35
-
-
77949268951
-
Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase
-
Bourron, O. et al. Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase. Diabetologia 53, 768-778 (2010).
-
(2010)
Diabetologia
, vol.53
, pp. 768-778
-
-
Bourron, O.1
-
36
-
-
75049085233
-
PKA phosphorylates and inactivates AMPKalpha to promote effcient lipolysis
-
Djouder, N. et al. PKA phosphorylates and inactivates AMPKalpha to promote effcient lipolysis. EMBO J. 29, 469-481 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 469-481
-
-
Djouder, N.1
-
37
-
-
79958047295
-
Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype
-
Ahmadian, M. et al. Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype. Cell Metab. 13, 739-748 (2011).
-
(2011)
Cell Metab.
, vol.13
, pp. 739-748
-
-
Ahmadian, M.1
-
38
-
-
84862567849
-
Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of infammatory cytokine gene expression and ROS production
-
Lin, L. et al. Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of infammatory cytokine gene expression and ROS production. Am. J. Physiol. Endocrinol. Metab. 302, E1550-E1559 (2012).
-
(2012)
Am. J. Physiol. Endocrinol. Metab.
, vol.302
, pp. E1550-E1559
-
-
Lin, L.1
-
39
-
-
4544220704
-
Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity
-
Um, S.H. et al. Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity. Nature 431, 200-205 (2004).
-
(2004)
Nature
, vol.431
, pp. 200-205
-
-
Um, S.H.1
-
40
-
-
0038043252
-
Adipose-specifc expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2
-
Horike, N. et al. Adipose-specifc expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2. J. Biol. Chem. 278, 18440-18447 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18440-18447
-
-
Horike, N.1
-
41
-
-
34250367531
-
JNK1 is required for the induction of Mkp1 expression in macrophages during proliferation and lipopolysaccharide-dependent activation
-
Sánchez-Tillo, E. et al. JNK1 Is required for the induction of Mkp1 expression in macrophages during proliferation and lipopolysaccharide-dependent activation. J. Biol. Chem. 282, 12566-12573 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 12566-12573
-
-
Sánchez-Tillo, E.1
-
42
-
-
0038832564
-
Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation
-
Brondello, J.M., Pouyssegur, J. & McKenzie, F.R. Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation. Science 286, 2514-2517 (1999).
-
(1999)
Science
, vol.286
, pp. 2514-2517
-
-
Brondello, J.M.1
Pouyssegur, J.2
McKenzie, F.R.3
-
43
-
-
33745353794
-
Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity
-
Wu, J.J. et al. Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity. Cell Metab. 4, 61-73 (2006).
-
(2006)
Cell Metab.
, vol.4
, pp. 61-73
-
-
Wu, J.J.1
-
44
-
-
84891929605
-
Nicotine elicits prolonged calcium signaling along ventral hippocampal axons
-
Zhong, C., Talmage, D.A. & Role, L.W. Nicotine elicits prolonged calcium signaling along ventral hippocampal axons. PLoS ONE 8, e82719 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e82719
-
-
Zhong, C.1
Talmage, D.A.2
Role, L.W.3
-
45
-
-
8344237497
-
Neuroscience. What genes tell us about nicotine addiction
-
Hogg, R.C. & Bertrand, D. Neuroscience. What genes tell us about nicotine addiction. Science 306, 983-985 (2004).
-
(2004)
Science
, vol.306
, pp. 983-985
-
-
Hogg, R.C.1
Bertrand, D.2
-
46
-
-
84870155127
-
Additive effects of nicotine and high-fat diet on hepatic steatosis in male mice
-
Friedman, T.C. et al. Additive effects of nicotine and high-fat diet on hepatic steatosis in male mice. Endocrinology 153, 5809-5820 (2012).
-
(2012)
Endocrinology
, vol.153
, pp. 5809-5820
-
-
Friedman, T.C.1
-
47
-
-
84899442593
-
Nicotine improves obesity and hepatic steatosis and ER stress in diet-induced obese male rats
-
Seoane-Collazo, P. et al. Nicotine improves obesity and hepatic steatosis and ER stress in diet-induced obese male rats. Endocrinology 155, 1679-1689 (2014).
-
(2014)
Endocrinology
, vol.155
, pp. 1679-1689
-
-
Seoane-Collazo, P.1
-
48
-
-
84871253591
-
Chronic exposure to nicotine enhances insulin sensitivity through alpha 7 nicotinic acetylcholine receptor-STAT3 pathway
-
Xu, T.Y. et al. Chronic exposure to nicotine enhances insulin sensitivity through alpha 7 nicotinic acetylcholine receptor-STAT3 pathway. PLoS ONE 7, e51217 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e51217
-
-
Xu, T.Y.1
-
49
-
-
33750578279
-
Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha
-
Yoon, M.J. et al. Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha. Diabetes 55, 2562-2570 (2006).
-
(2006)
Diabetes
, vol.55
, pp. 2562-2570
-
-
Yoon, M.J.1
-
50
-
-
33644863486
-
Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling
-
Lin, Y.W. & Yang, J.L. Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling. J. Biol. Chem. 281, 915-926 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 915-926
-
-
Lin, Y.W.1
Yang, J.L.2
-
51
-
-
77957832253
-
Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway
-
Choi, S.M. et al. Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway. Mol. Cell. Biol. 30, 5009-5020 (2010).
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 5009-5020
-
-
Choi, S.M.1
-
52
-
-
4344714725
-
Induced adiposity and adipocyte hypertrophy in mice lacking the AMP-activated protein kinase-alpha2 subunit
-
Villena, J.A. et al. Induced adiposity and adipocyte hypertrophy in mice lacking the AMP-activated protein kinase-alpha2 subunit. Diabetes 53, 2242-2249 (2004).
-
(2004)
Diabetes
, vol.53
, pp. 2242-2249
-
-
Villena, J.A.1
-
53
-
-
0029945325
-
Stimulation of adipose tissue lipolysis following insulin-induced hypoglycaemia: Evidence of increased beta-adrenoceptor-mediated lipolytic response in IDDM
-
Bolinder, J., Sjoberg, S. & Arner, P. Stimulation of adipose tissue lipolysis following insulin-induced hypoglycaemia: evidence of increased beta-adrenoceptor-mediated lipolytic response in IDDM. Diabetologia 39, 845-853 (1996).
-
(1996)
Diabetologia
, vol.39
, pp. 845-853
-
-
Bolinder, J.1
Sjoberg, S.2
Arner, P.3
-
54
-
-
0024335705
-
A randomized crossover study of sulphonylurea and insulin treatment in patients with type 2 diabetes poorly controlled on dietary therapy
-
Wolffenbuttel, B.H., Weber, R.F., van Koetsveld, P.M., Weeks, L. & Verschoor, L. A randomized crossover study of sulphonylurea and insulin treatment in patients with type 2 diabetes poorly controlled on dietary therapy. Diabet. Med. 6, 520-525 (1989).
-
(1989)
Diabet. Med.
, vol.6
, pp. 520-525
-
-
Wolffenbuttel, B.H.1
Weber, R.F.2
Van Koetsveld, P.M.3
Weeks, L.4
Verschoor, L.5
-
55
-
-
0023625723
-
Constant-rate infusion of nicotine and cotinine. I. A physiological pharmacokinetic analysis of the cotinine disposition, and effects on clearance and distribution in the rat
-
Gabrielsson, J. & Bondesson, U. Constant-rate infusion of nicotine and cotinine. I. A physiological pharmacokinetic analysis of the cotinine disposition, and effects on clearance and distribution in the rat. J. Pharmacokinet. Biopharm. 15, 583-599 (1987).
-
(1987)
J. Pharmacokinet. Biopharm.
, vol.15
, pp. 583-599
-
-
Gabrielsson, J.1
Bondesson, U.2
-
56
-
-
84888197890
-
Adenosine monophosphate-activated protein kinase-alpha2 defciency promotes vascular smooth muscle cell migration via S-phase kinase-associated protein 2 upregulation and E-cadherin downregulation
-
Song, P. et al. Adenosine monophosphate-activated protein kinase-alpha2 defciency promotes vascular smooth muscle cell migration via S-phase kinase-associated protein 2 upregulation and E-cadherin downregulation. Arterioscler. Thromb. Vasc. Biol. 33, 2800-2809 (2013).
-
(2013)
Arterioscler. Thromb. Vasc. Biol.
, vol.33
, pp. 2800-2809
-
-
Song, P.1
-
57
-
-
0029757347
-
Disruption of the erp/mkp-1 gene does not affect mouse development: Normal MAP kinase activity in ERP/MKP-1-defcient fbroblasts
-
Dorfman, K. et al. Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-defcient fbroblasts. Oncogene 13, 925-931 (1996).
-
(1996)
Oncogene
, vol.13
, pp. 925-931
-
-
Dorfman, K.1
-
58
-
-
84859452677
-
Yin Yang 1 defciency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling
-
Blättler, S.M. et al. Yin Yang 1 defciency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling. Cell Metab. 15, 505-517 (2012).
-
(2012)
Cell Metab.
, vol.15
, pp. 505-517
-
-
Blättler, S.M.1
-
59
-
-
84878871217
-
Distinct patterns of tissue-specifc lipid accumulation during the induction of insulin resistance in mice by high-fat feeding
-
Turner, N. et al. Distinct patterns of tissue-specifc lipid accumulation during the induction of insulin resistance in mice by high-fat feeding. Diabetologia 56, 1638-1648 (2013).
-
(2013)
Diabetologia
, vol.56
, pp. 1638-1648
-
-
Turner, N.1
-
60
-
-
81055144760
-
Adipocyte NCoR knockout decreases PPARgamma phosphorylation and enhances PPARgamma activity and insulin sensitivity
-
Li, P. et al. Adipocyte NCoR knockout decreases PPARgamma phosphorylation and enhances PPARgamma activity and insulin sensitivity. Cell 147, 815-826 (2011).
-
(2011)
Cell
, vol.147
, pp. 815-826
-
-
Li, P.1
-
61
-
-
84883692803
-
Liver kinase b1 is required for white adipose tissue growth and differentiation
-
Zhang, W., Wang, Q., Song, P. & Zou, M.H. Liver kinase b1 is required for white adipose tissue growth and differentiation. Diabetes 62, 2347-2358 (2013).
-
(2013)
Diabetes
, vol.62
, pp. 2347-2358
-
-
Zhang, W.1
Wang, Q.2
Song, P.3
Zou, M.H.4
-
62
-
-
0030698379
-
Cigarette smoking and insulin resistance in patients with noninsulin-dependent diabetes mellitus
-
Targher, G. et al. Cigarette smoking and insulin resistance in patients with noninsulin-dependent diabetes mellitus. J. Clin. Endocrinol. Metab. 82, 3619-3624 (1997).
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 3619-3624
-
-
Targher, G.1
-
63
-
-
0034693232
-
Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice
-
Coburn, C.T. et al. Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. J. Biol. Chem. 275, 32523-32529 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32523-32529
-
-
Coburn, C.T.1
-
64
-
-
0035824678
-
Post-transcriptional stimulation of the assembly and secretion of triglyceride-rich apolipoprotein B lipoproteins in a mouse with selective defciency of brown adipose tissue, obesity, and insulin resistance
-
Siri, P. et al. Post-transcriptional stimulation of the assembly and secretion of triglyceride-rich apolipoprotein B lipoproteins in a mouse with selective defciency of brown adipose tissue, obesity, and insulin resistance. J. Biol. Chem. 276, 46064-46072 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46064-46072
-
-
Siri, P.1
-
65
-
-
84863281299
-
Inhibition of AMP-activated protein kinase alpha (AMPKα) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fbroblasts and cardiomyocytes: Role of p53 and SIRT1
-
Wang, S., Song, P. & Zou, M.H. Inhibition of AMP-activated protein kinase alpha (AMPKα) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fbroblasts and cardiomyocytes: role of p53 and SIRT1. J. Biol. Chem. 287, 8001-8012 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 8001-8012
-
-
Wang, S.1
Song, P.2
Zou, M.H.3
-
66
-
-
67650083087
-
Identifcation of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis
-
Xie, Z.L. et al. Identifcation of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. Mol. Cell. Biol. 29, 3582-3596 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3582-3596
-
-
Xie, Z.L.1
|