Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK

Journal of Steroid Biochemistry and Molecular Biology

Volumn 155, Issue , 2016, Pages 155-165

  Chen, Yan ^a   Xu, Xiaoshan ^a   Zhang, Yuanyuan ^a   Liu, Kang ^a   Huang, Fang ^a   Liu, Baolin ^a   Kou, Junping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

AMPK; Diosgenin; Endothelial dysfunction; Inflammation; Perivascular adipose tissue

Indexed keywords

ADENYLATE KINASE; ADIPOCYTOKINE; ADIPONECTIN; ARGINASE 1; DIOSGENIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RESVERATROL; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; NONHUMAN; PROADIPOCYTE; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; VASODILATATION; WESTERN BLOTTING; 3T3 CELL LINE; ADVERSE EFFECTS; ANIMAL; DRUG EFFECTS; GENETICS; LIPID DIET; METABOLISM; MOUSE; ORAL DRUG ADMINISTRATION; PANNICULITIS; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM;

3T3-L1 CELLS; ADIPOKINES; ADIPOSE TISSUE; ADMINISTRATION, ORAL; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTI-INFLAMMATORY AGENTS; DIET, HIGH-FAT; DIOSGENIN; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; MICE; PANNICULITIS; RATS, SPRAGUE-DAWLEY; VASODILATION;

EID: 84946911785     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2015.07.005     Document Type: Article

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