Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1

Pharmacological Research

Volumn 89, Issue , 2014, Pages 19-28

  Sun, Yan ^a   Li, Jia ^a   Xiao, Na ^a   Wang, Meng ^b   Kou, Junping ^a   Qi, Lianwen ^a   Huang, Fang ^a   Liu, Baolin ^a   Liu, Kang ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b University of Macau   (Macao)

Author keywords

AMP activated protein kinase; Endothelial dysfunction; Perivascular adipose tissue; Sirtuin 1

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ADIPOCYTOKINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERLEUKIN 6; METFORMIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NICOTINAMIDE; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RESVERATROL; SALICYLIC ACID; SIRTUIN 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ACETYLCHOLINE; ADIPONECTIN; FRUCTOSE; SALICYLATE SODIUM; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; AICA RIBONUCLEOTIDE; CULTURE MEDIUM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RIBONUCLEOTIDE; STILBENE DERIVATIVE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DRUG ANTAGONISM; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVATION; ENZYME REGULATION; GLUCOSE METABOLISM; HOMEOSTASIS; HYPERGLYCEMIA; HYPERLIPIDEMIA; LIPID METABOLISM; NONHUMAN; OBESITY; PERIVASCULAR ADIPOSE TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; UPREGULATION; VASODILATATION; ENZYME INHIBITION; PROTEIN SYNTHESIS INHIBITION; REGULATORY MECHANISM; ANALOGS AND DERIVATIVES; ANIMAL; AORTA; CULTURE MEDIUM; DIET; DRUG EFFECTS; METABOLISM; PHARMACOLOGY;

ADIPOKINES; ADIPOSE TISSUE; AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AORTA; CULTURE MEDIA, CONDITIONED; DIET; FRUCTOSE; METFORMIN; NF-KAPPA B; PALMITIC ACID; RATS; RIBONUCLEOTIDES; SIRTUIN 1; SODIUM SALICYLATE; STILBENES; VASODILATION;

EID: 84906482561     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2014.07.006     Document Type: Article

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