메뉴 건너뛰기




Volumn 31, Issue 12, 2011, Pages 2897-2908

AMP-activated protein kinase suppresses endothelial cell inflammation through phosphorylation of transcriptional coactivator p300

Author keywords

AMPK; inflammation; p300; vascular biology

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; 6,7 DIHYDRO 4 HYDROXY 3 (2' HYDROXY 1,1' BIPHENYL 4 YL) 6 OXOTHIENO[2,3 B]PYRIDINE 5 CARBONITRILE; HISTONE ACETYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; PROTEIN P300; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

EID: 81755174323     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.111.237453     Document Type: Article
Times cited : (111)

References (48)
  • 1
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999; 340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 2
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: A double-edged sword
    • DOI 10.1038/nri1882, PII N1882
    • Hansson GK, Libby P. The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol. 2006;6:508-519. (Pubitemid 43980523)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.7 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 3
    • 36048979880 scopus 로고    scopus 로고
    • Vascular adhesion molecules in atherosclerosis
    • DOI 10.1161/ATVBAHA.107.149179, PII 0004360520071100000005
    • Galkina E, Ley K. Vascular adhesion molecules in atherosclerosis. Arterioscler Thromb Vasc Biol. 2007;27:2292-2301. (Pubitemid 350203942)
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , Issue.11 , pp. 2292-2301
    • Galkina, E.1    Ley, K.2
  • 4
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis: The road ahead
    • DOI 10.1016/S0092-8674(01)00238-0
    • Glass CK, Witztum JL. Atherosclerosis: the road ahead. Cell. 2001;104: 503-516. (Pubitemid 32201946)
    • (2001) Cell , vol.104 , Issue.4 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 6
    • 34547911052 scopus 로고    scopus 로고
    • Chemistry of acetyl transfer by histone modifying enzymes: Structure, mechanism and implications for effector design
    • DOI 10.1038/sj.onc.1210619, PII 1210619
    • Hodawadekar SC, Marmorstein R. Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design. Oncogene. 2007;26:5528-5540. (Pubitemid 47255933)
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5528-5540
    • Hodawadekar, S.C.1    Marmorstein, R.2
  • 7
    • 33646502826 scopus 로고    scopus 로고
    • The transcriptional regulatory code of eukaryotic cells: Insights from genomewide analysis of chromatin organization and transcription factor binding
    • Barrera LO, Ren B. The transcriptional regulatory code of eukaryotic cells: insights from genomewide analysis of chromatin organization and transcription factor binding. Curr Opin Cell Biol. 2006;18:291-298.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 291-298
    • Barrera, L.O.1    Ren, B.2
  • 9
    • 0034916613 scopus 로고    scopus 로고
    • P300/CBP proteins: HATs for transcriptional bridges and scaffolds
    • Chan HM, La Thangue NB. p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J Cell Sci. 2001;114:2363-2373. (Pubitemid 32684792)
    • (2001) Journal of Cell Science , vol.114 , Issue.13 , pp. 2363-2373
    • Chan, H.M.1    La Thangue, N.B.2
  • 10
    • 0036234551 scopus 로고    scopus 로고
    • Selective requirements for histone H3 and H4 N termini in p300-dependent transcriptional activation from chromatin
    • DOI 10.1016/S1097-2765(02)00497-5
    • An W, Palhan VB, Karymov MA, Leuba SH, Roeder RG. Selective requirements for histone H3 and H4 N termini in p300-dependent transcriptional activation from chromatin. Mol Cell. 2002;9:811-821. (Pubitemid 34454891)
    • (2002) Molecular Cell , vol.9 , Issue.4 , pp. 811-821
    • An, W.1    Palhan, V.B.2    Karymov, M.A.3    Leuba, S.H.4    Roeder, R.G.5
  • 11
    • 51549118740 scopus 로고    scopus 로고
    • PKC2II augments NF-2B-dependent transcription at the CCL11 promoter via p300/CBP-associated factor recruitment and histone H4 acetylation
    • Clarke DL, Sutcliffe A, Deacon K, Bradbury D, Corbett L, Knox AJ. PKC2II augments NF-2B-dependent transcription at the CCL11 promoter via p300/CBP-associated factor recruitment and histone H4 acetylation. J Immunol. 2008;181:3503-3514.
    • (2008) J Immunol , vol.181 , pp. 3503-3514
    • Clarke, D.L.1    Sutcliffe, A.2    Deacon, K.3    Bradbury, D.4    Corbett, L.5    Knox, A.J.6
  • 12
    • 36248983372 scopus 로고    scopus 로고
    • Krüppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation
    • DOI 10.1074/jbc.M701847200
    • Evans PM, Zhang W, Chen X, Yang J, Bhakat KK, Liu C. Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation. J Biol Chem. 2007;282:33994-34002. (Pubitemid 350159428)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.47 , pp. 33994-34002
    • Evans, P.M.1    Zhang, W.2    Chen, X.3    Yang, J.4    Bhakat, K.K.5    Liu, C.6
  • 13
    • 34548763920 scopus 로고    scopus 로고
    • Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-2B, and p300 pathway in microglia
    • Tang CH, Lu DY, Yang RS, Tsai HY, Kao MC, Fu WM, Chen YF. Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-2B, and p300 pathway in microglia. J Immunol. 2007;179:1292-1302.
    • (2007) J Immunol , vol.179 , pp. 1292-1302
    • Tang, C.H.1    Lu, D.Y.2    Yang, R.S.3    Tsai, H.Y.4    Kao, M.C.5    Fu, W.M.6    Chen, Y.F.7
  • 14
    • 0037152277 scopus 로고    scopus 로고
    • Inhibition of histone acetyltransferase function of p300 by PKC
    • Yuan LW, Soh JW, Weinstein IB. Inhibition of histone acetyltransferase function of p300 by PKC. Biochim Biophys Acta. 2002;1592:205-211.
    • (2002) Biochim Biophys Acta , vol.1592 , pp. 205-211
    • Yuan, L.W.1    Soh, J.W.2    Weinstein, I.B.3
  • 15
    • 0034731524 scopus 로고    scopus 로고
    • Phosphorylation of p300 at serine 89 by protein kinase C
    • DOI 10.1074/jbc.M007832200
    • Yuan LW, Gambee JE. Phosphorylation of p300 at serine 89 by protein kinase C. J Biol Chem. 2000;275:40946-40951. (Pubitemid 32054918)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.52 , pp. 40946-40951
    • Yuan, L.W.1    Gambee, J.E.2
  • 16
    • 78649855297 scopus 로고    scopus 로고
    • Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice
    • Bricambert J, Miranda J, Benhamed F, Girard J, Postic C, Dentin R. Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice. J Clin Invest. 2010;120:4316-4331.
    • (2010) J Clin Invest , vol.120 , pp. 4316-4331
    • Bricambert, J.1    Miranda, J.2    Benhamed, F.3    Girard, J.4    Postic, C.5    Dentin, R.6
  • 17
    • 56449117024 scopus 로고    scopus 로고
    • AMPK: A metabolic gauge regulating whole-body energy homeostasis
    • Lage R, Diéguez C, Vidal-Puig A, López M. AMPK: a metabolic gauge regulating whole-body energy homeostasis. Trends Mol Med. 2008;14: 539-549.
    • (2008) Trends Mol Med , vol.14 , pp. 539-549
    • Lage, R.1    Diéguez, C.2    Vidal-Puig, A.3    López, M.4
  • 18
    • 34648828532 scopus 로고    scopus 로고
    • AMP-activated/SNF1 protein kinases: Conserved guardians of cellular energy
    • DOI 10.1038/nrm2249, PII NRM2249
    • Hardie DG. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat Rev Mol Cell Biol. 2007;8:774-785. (Pubitemid 47462132)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.10 , pp. 774-785
    • Hardie, D.G.1
  • 19
    • 66249092436 scopus 로고    scopus 로고
    • Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via AMP-activated protein kinase and eNOS
    • Wang Y, Huang Y, Lam KS, Li Y, Wong WT, Ye H, Lau CW, Vanhoutte PM, Xu A. Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via AMP-activated protein kinase and eNOS. Cardiovasc Res. 2009;82:484-492.
    • (2009) Cardiovasc Res , vol.82 , pp. 484-492
    • Wang, Y.1    Huang, Y.2    Lam, K.S.3    Li, Y.4    Wong, W.T.5    Ye, H.6    Lau, C.W.7    Vanhoutte, P.M.8    Xu, A.9
  • 21
    • 77953960882 scopus 로고    scopus 로고
    • Adenosine monophosphate activated protein kinase regulates ABCG1-mediated oxysterol efflux from endothelial cells and protects against hypercholesterolemia-induced endothelial dysfunction
    • Li D, Zhang Y, Ma J, Ling W, Xia M. Adenosine monophosphate activated protein kinase regulates ABCG1-mediated oxysterol efflux from endothelial cells and protects against hypercholesterolemia-induced endothelial dysfunction. Arterioscler Thromb Vasc Biol. 2010;30: 1354-1362.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1354-1362
    • Li, D.1    Zhang, Y.2    Ma, J.3    Ling, W.4    Xia, M.5
  • 26
    • 0035831465 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression of ICAM-1, VCAM-1 and E-selectin through NF2B activation in endothelial cells
    • Kim I, Moon S-O, Hoon Kim S, Jin Kim H, Soon Koh Y, Young Koh G. Vascular endothelial growth factor expression of ICAM-1, VCAM-1 and E-selectin through NF2B activation in endothelial cells. J Biol Chem. 2001;276:7614-7620.
    • (2001) J Biol Chem , vol.276 , pp. 7614-7620
    • Kim, I.1    Moon, S.-O.2    Hoon Kim, S.3    Jin Kim, H.4    Soon Koh, Y.5    Young Koh, G.6
  • 27
    • 30744458869 scopus 로고    scopus 로고
    • IκB kinase α-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300
    • DOI 10.1128/MCB.26.2.457-471.2006
    • Hoberg JE, Popko AE, Ramsey CS, Mayo MW. I2B kinasë-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300. Mol Cell Biol. 2006;26:457-471. (Pubitemid 43090920)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.2 , pp. 457-471
    • Hoberg, J.E.1    Popko, A.E.2    Ramsey, C.S.3    Mayo, M.W.4
  • 28
    • 0027431089 scopus 로고
    • Molecular cloning and characterization of PKC(t), an atypical isoform of protein kinase C derived from insulin-secreting cells
    • Selbie LA, Schmitz-Peiffer C, Sheng Y, Biden TJ. Molecular cloning and characterization of PKC2, an atypical isoform of protein kinase C derived from insulin-secreting cells. J Biol Chem. 1993;268: 24296-24302. (Pubitemid 23335419)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.32 , pp. 24296-24302
    • Selbie, L.A.1    Schmitz-Peiffer, C.2    Sheng, Y.3    Biden, T.J.4
  • 29
    • 65549136655 scopus 로고    scopus 로고
    • Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein
    • He L, Sabet A, Djedjos S, Miller R, Sun X, Hussain MA, Radovick S, Wondisford FE. Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein. Cell. 2009;137: 635-646.
    • (2009) Cell , vol.137 , pp. 635-646
    • He, L.1    Sabet, A.2    Djedjos, S.3    Miller, R.4    Sun, X.5    Hussain, M.A.6    Radovick, S.7    Wondisford, F.E.8
  • 30
    • 21244437079 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide ribonucleoside: A novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis
    • Nath N, Giri S, Prasad R, Salem ML, Singh AK, Singh I. 5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis. J Immunol. 2005; 175:566-574. (Pubitemid 40884363)
    • (2005) Journal of Immunology , vol.175 , Issue.1 , pp. 566-574
    • Nath, N.1    Giri, S.2    Prasad, R.3    Salem, M.L.4    Singh, A.K.5    Singh, I.6
  • 33
    • 77953517927 scopus 로고    scopus 로고
    • Macrophagë1 AMP-activated protein kinase (f1AMPK) antagonizes fatty acid-induced inflammation through SIRT1
    • Yang Z, Kahn BB, Shi H, Xue BZ. Macrophagë1 AMP-activated protein kinase (f1AMPK) antagonizes fatty acid-induced inflammation through SIRT1. J Biol Chem. 2010;285:19051-19059.
    • (2010) J Biol Chem , vol.285 , pp. 19051-19059
    • Yang, Z.1    Kahn, B.B.2    Shi, H.3    Xue, B.Z.4
  • 34
    • 77956229580 scopus 로고    scopus 로고
    • AICAR induces cyclooxygenase-2 expression through AMP-activated protein kinase-transforming growth factor-2-activated kinase 1-p38 mitogen-activated protein kinase signaling pathway
    • Chang MY, Ho FM, Wang JS, Kang HC, Chang Y, Ye ZX, Lin WW. AICAR induces cyclooxygenase-2 expression through AMP-activated protein kinase-transforming growth factor-2-activated kinase 1-p38 mitogen-activated protein kinase signaling pathway. Biochem Pharmacol. 2010;80:1210-1220.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1210-1220
    • Chang, M.Y.1    Ho, F.M.2    Wang, J.S.3    Kang, H.C.4    Chang, Y.5    Ye, Z.X.6    Lin, W.W.7
  • 35
    • 57549088860 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase
    • Ewart MA, Kohlhaas CF, Salt IP. Inhibition of tumor necrosis factor alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase. Arterioscler Thromb Vasc Biol. 2008;28: 2255-2257.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2255-2257
    • Ewart, M.A.1    Kohlhaas, C.F.2    Salt, I.P.3
  • 36
    • 79955072785 scopus 로고    scopus 로고
    • Isoform-selective 5r-AMP-activated protein kinase-dependent preconditioning mechanisms to prevent postischemic leukocyte-endothelial cell adhesive interactions
    • Gaskin FS, Kamada K, Zuidema MY, Jones AW, Rubin LJ, Korthuis RJ. Isoform-selective 5r-AMP-activated protein kinase-dependent preconditioning mechanisms to prevent postischemic leukocyte-endothelial cell adhesive interactions. Am J Physiol Heart Circ Physiol. 2011;300: H1352-H1360.
    • (2011) Am J Physiol Heart Circ Physiol , vol.300
    • Gaskin, F.S.1    Kamada, K.2    Zuidema, M.Y.3    Jones, A.W.4    Rubin, L.J.5    Korthuis, R.J.6
  • 38
    • 33644747421 scopus 로고    scopus 로고
    • Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase
    • DOI 10.2337/diabetes.55.02.06.db05-1064
    • Davis BJ, Xie Z, Viollet B, Zou MH. Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase. Diabetes. 2006;55:496-505. (Pubitemid 43343281)
    • (2006) Diabetes , vol.55 , Issue.2 , pp. 496-505
    • Davis, B.J.1    Xie, Z.2    Viollet, B.3    Zou, M.-H.4
  • 39
    • 34548302084 scopus 로고    scopus 로고
    • Endothelial-dependent mechanisms of leukocyte recruitment to the vascular wall
    • DOI 10.1161/CIRCRESAHA.107.151860b, PII 0000301220070803000008
    • Rao RM, Yang L, Garcia-Cardena G, Luscinskas FW. Endothelialdependent mechanisms of leukocyte recruitment to the vascular wall. Circ Res. 2007;101:234-247. (Pubitemid 47344073)
    • (2007) Circulation Research , vol.101 , Issue.3 , pp. 234-247
    • Rao, R.M.1    Yang, L.2    Garcia-Cardena, G.3    Luscinskas, F.W.4
  • 41
    • 0037011056 scopus 로고    scopus 로고
    • Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-κB
    • DOI 10.1093/emboj/cdf660
    • Chen LF, Mu Y, Greene WC. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-2B. EMBO J. 2002;21: 6539-6548. (Pubitemid 35448431)
    • (2002) EMBO Journal , vol.21 , Issue.23 , pp. 6539-6548
    • Chen, L.-F.1    Mu, Y.2    Greene, W.C.3
  • 42
    • 0030797585 scopus 로고    scopus 로고
    • Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
    • DOI 10.1016/S0092-8674(00)80521-8
    • Gu W, Roeder RG. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell. 1997;90:595-606. (Pubitemid 27357952)
    • (1997) Cell , vol.90 , Issue.4 , pp. 595-606
    • Gu, W.1    Roeder, R.G.2
  • 43
    • 66349129338 scopus 로고    scopus 로고
    • Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response
    • Sun Z, Chin YE, Zhang DD. Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response. Mol Cell Biol. 2009;29:2658-2672.
    • (2009) Mol Cell Biol , vol.29 , pp. 2658-2672
    • Sun, Z.1    Chin, Y.E.2    Zhang, D.D.3
  • 44
    • 0033636892 scopus 로고    scopus 로고
    • Acetylation regulates transcription factor activity at multiple levels
    • Soutoglou E, Katrakili N, Talianidis I. Acetylation regulates transcription factor activity at multiple levels. Mol Cell. 2000;5:745-751.
    • (2000) Mol Cell , vol.5 , pp. 745-751
    • Soutoglou, E.1    Katrakili, N.2    Talianidis, I.3
  • 45
    • 33644849325 scopus 로고    scopus 로고
    • Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling after myocardial infarction in adult mice in vivo
    • Miyamoto S, Kawamura T, Morimoto T, Ono K, Wada H, Kawase Y, Matsumori A, Nishio R, Kita T, Hasegawa K. Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling after myocardial infarction in adult mice in vivo. Circulation. 2006;113:679-690.
    • (2006) Circulation , vol.113 , pp. 679-690
    • Miyamoto, S.1    Kawamura, T.2    Morimoto, T.3    Ono, K.4    Wada, H.5    Kawase, Y.6    Matsumori, A.7    Nishio, R.8    Kita, T.9    Hasegawa, K.10
  • 46
    • 0035914324 scopus 로고    scopus 로고
    • Regulation of transcription by AMP-activated protein kinase: Phosphorylation of p300 blocks its interaction with nuclear receptors
    • Yang W, Hong YH, Shen XQ, Frankowski C, Camp HS, Leff T. Regulation of transcription by AMP-activated protein kinase: phosphorylation of p300 blocks its interaction with nuclear receptors. J Biol Chem. 2001;276:38341-38344.
    • (2001) J Biol Chem , vol.276 , pp. 38341-38344
    • Yang, W.1    Hong, Y.H.2    Shen, X.Q.3    Frankowski, C.4    Camp, H.S.5    Leff, T.6
  • 47
    • 0030606239 scopus 로고    scopus 로고
    • The transcriptional coactivators p300 and CBP are histone acetyltransferases
    • DOI 10.1016/S0092-8674(00)82001-2
    • Ogryzko VV, Schiltz RL, Russanova V, Howard BH, Nakatani Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell. 1996;87:953-959. (Pubitemid 26404293)
    • (1996) Cell , vol.87 , Issue.5 , pp. 953-959
    • Ogryzko, V.V.1    Schiltz, R.L.2    Russanova, V.3    Howard, B.H.4    Nakatani, Y.5
  • 48
    • 0037287298 scopus 로고    scopus 로고
    • Protein kinase C λ/ι (PKCλ/ι: A PKC isotype essential for the development of multicellular organisms
    • DOI 10.1093/jb/mvg018
    • Suzuki A, Akimoto K, Ohno S. Protein kinase C2/F(PKC2/F): a PKC isotype essential for the development of multicellular organisms. J Biochem. 2003;133:9-16. (Pubitemid 36240973)
    • (2003) Journal of Biochemistry , vol.133 , Issue.1 , pp. 9-16
    • Suzuki, A.1    Akimoto, K.2    Ohno, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.