Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

Journal of Clinical Investigation

Volumn 121, Issue 12, 2011, Pages 4903-4915

  Galic, Sandra ^a   Fullerton, Morgan D ^b   Schertzer, Jonathan D ^b   Sikkema, Sarah ^b   Marcinko, Katarina ^b   Walkley, Carl R ^a   Izon, David ^a   Honeyman, Jane ^a   Chen, Zhi Ping ^a   Van Denderen, Bryce J ^a   Kemp, Bruce E ^a   Steinberg, Gregory R ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; DIACYLGLYCEROL; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE BETA1; INSULIN; LIPID; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FATTY ACID OXIDATION; GENE DELETION; IN VIVO STUDY; INFLAMMATION; INSULIN RESISTANCE; MACROPHAGE; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ADIPOSE TISSUE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DIETARY FATS; DIGLYCERIDES; ENZYME ACTIVATION; FATTY ACIDS; HEMATOPOIETIC STEM CELLS; HEPATITIS; INSULIN RESISTANCE; LYMPHOCYTE ACTIVATION; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, KNOCKOUT; MICE, OBESE; MITOCHONDRIA; OBESITY; OXIDATION-REDUCTION; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RADIATION CHIMERA; SPECIFIC PATHOGEN-FREE ORGANISMS; T-LYMPHOCYTES;

EID: 84055190798     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI58577     Document Type: Article

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