-
1
-
-
84860521413
-
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma
-
Abdelwahab, M. G., Fenton, K. E., Preul, M. C., Rho, J. M., Lynch, A., Stafford, P., et al. (2012). The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma. PLoS One 7:e36197. doi: 10.1371/journal.pone.0036197
-
(2012)
Plos One
, vol.7
-
-
Abdelwahab, M.G.1
Fenton, K.E.2
Preul, M.C.3
Rho, J.M.4
Lynch, A.5
Stafford, P.6
-
2
-
-
84904562699
-
Dietary PUFA and cancer
-
Abel, S., Riedel, S., and Gelderblom, W. C. A. (2014). Dietary PUFA and cancer. Proc. Nutr. Soc. 73, 361-367. doi: 10.1017/s0029665114000585
-
(2014)
Proc. Nutr. Soc
, vol.73
, pp. 361-367
-
-
Abel, S.1
Riedel, S.2
Gelderblom, W.C.A.3
-
3
-
-
84908574610
-
Ketogenic diets as an adjuvant cancer therapy: History and potential mechanism
-
Allen, B. G., Bhatia, S. K., Anderson, C. M., Eichenberger-Gilmore, J. M., Sibenaller, Z. A., Mapuskar, K. A., et al. (2014). Ketogenic diets as an adjuvant cancer therapy: history and potential mechanism. Redox Biol. 2, 963-970. doi: 10.1016/j.redox.2014.08.002
-
(2014)
Redox Biol
, vol.2
, pp. 963-970
-
-
Allen, B.G.1
Bhatia, S.K.2
Anderson, C.M.3
Eichenberger-Gilmore, J.M.4
Sibenaller, Z.A.5
Mapuskar, K.A.6
-
4
-
-
84881135707
-
Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts
-
Allen, B. G., Bhatia, S. K., Buatti, J. M., Brandt, K. E., Lindholm, K. E., Button, A. M., et al. (2013). Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts. Clin. Cancer Res. 19, 3905-3913. doi: 10.1158/1078-0432.CCR-12-0287
-
(2013)
Clin. Cancer Res
, vol.19
, pp. 3905-3913
-
-
Allen, B.G.1
Bhatia, S.K.2
Buatti, J.M.3
Brandt, K.E.4
Lindholm, K.E.5
Button, A.M.6
-
5
-
-
84941773651
-
MYC disrupts the circadian clock and metabolism in cancer cells
-
Altman, B. J., Hsieh, A. L., Sengupta, A., Krishnanaiah, S. Y., Stine, Z. E., Walton, Z. E., et al. (2015). MYC disrupts the circadian clock and metabolism in cancer cells. Cell Metab. 22, 1009-1019. doi: 10.1016/j.cmet.2015.09.003
-
(2015)
Cell Metab
, vol.22
, pp. 1009-1019
-
-
Altman, B.J.1
Hsieh, A.L.2
Sengupta, A.3
Krishnanaiah, S.Y.4
Stine, Z.E.5
Walton, Z.E.6
-
6
-
-
65649115060
-
Hypoxia helps glioma to fight therapy
-
Amberger-Murphy, V. (2009). Hypoxia helps glioma to fight therapy. Curr. Cancer Drug Targets 9, 381-390. doi: 10.2174/156800909788166637
-
(2009)
Curr. Cancer Drug Targets
, vol.9
, pp. 381-390
-
-
Amberger-Murphy, V.1
-
7
-
-
84959220502
-
Interplay between metabolism and oncogenic process: Role of microRNAs
-
Arora, A., Singh, S., Bhatt, A. N., Pandey, S., Sandhir, R., and Dwarakanath, B. S. (2015). Interplay between metabolism and oncogenic process: role of microRNAs. Transl. Oncogenomics 7, 11-27. doi: 10.4137/TOG.S29652
-
(2015)
Transl. Oncogenomics
, vol.7
, pp. 11-27
-
-
Arora, A.1
Singh, S.2
Bhatt, A.N.3
Pandey, S.4
Sandhir, R.5
Dwarakanath, B.S.6
-
8
-
-
84955287687
-
PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives
-
Asati, V., Mahapatra, D. K., and Bharti, S. K. (2016). PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: structural and pharmacological perspectives. Eur. J. Med. Chem. 109, 314-341. doi: 10.1016/j.ejmech.2016.01.012
-
(2016)
Eur. J. Med. Chem
, vol.109
, pp. 314-341
-
-
Asati, V.1
Mahapatra, D.K.2
Bharti, S.K.3
-
9
-
-
84959463734
-
Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment
-
Barron, C. C., Bilan, P. J., Tsakiridis, T., and Tsiani, E. (2016). Facilitative glucose transporters: implications for cancer detection, prognosis and treatment. Metabolism 65, 124-139. doi: 10.1016/j.metabol.2015.10.007
-
(2016)
Metabolism
, vol.65
, pp. 124-139
-
-
Barron, C.C.1
Bilan, P.J.2
Tsakiridis, T.3
Tsiani, E.4
-
10
-
-
84961288801
-
The interaction between epigenetics, nutrition and the development of cancer
-
Bishop, K. S., and Ferguson, L. R. (2015). The interaction between epigenetics, nutrition and the development of cancer. Nutrients 7, 922-947. doi: 10.3390/nu7020922
-
(2015)
Nutrients
, vol.7
, pp. 922-947
-
-
Bishop, K.S.1
Ferguson, L.R.2
-
11
-
-
84885472358
-
Health-related quality of life of significant others of patients with malignant CNS versus non-CNS tumors: A comparative study
-
Boele, F. W., Heimans, J. J., Aaronson, N. K., Taphoorn, M. J., Postma, T. J., Reijneveld, J. C., et al. (2013). Health-related quality of life of significant others of patients with malignant CNS versus non-CNS tumors: a comparative study. J. Neurooncol. 115, 87-94. doi: 10.1007/s11060-013-1198-z
-
(2013)
J. Neurooncol
, vol.115
, pp. 87-94
-
-
Boele, F.W.1
Heimans, J.J.2
Aaronson, N.K.3
Taphoorn, M.J.4
Postma, T.J.5
Reijneveld, J.C.6
-
12
-
-
84925969707
-
Metabolic pathways promoting cancer cell survival and growth. Nat
-
Boroughs, L. K., and DeBerardinis, R. J. (2015). Metabolic pathways promoting cancer cell survival and growth. Nat. Cell Biol. 17, 351-359. doi: 10.1038/ncb3124
-
(2015)
Cell Biol
, vol.17
, pp. 351-359
-
-
Boroughs, L.K.1
Deberardinis, R.J.2
-
13
-
-
85121351214
-
Energy disruptors: Rising stars in anticancer therapy?
-
Bost, F., Decoux-Poullot, A. G., Tanti, J. F., and Clavel, S. (2016). Energy disruptors: rising stars in anticancer therapy? Oncogenesis 5:e188. doi: 10.1038/oncsis.2015.46
-
(2016)
Oncogenesis
, vol.5
-
-
Bost, F.1
Decoux-Poullot, A.G.2
Tanti, J.F.3
Clavel, S.4
-
15
-
-
84868019043
-
Cancer cell metabolism: One hallmark, many faces
-
Cantor, J. R., and Sabatini, D. M. (2012). Cancer cell metabolism: one hallmark, many faces. Cancer Discov. 2, 881-898. doi: 10.1158/2159-8290.CD-12-0345
-
(2012)
Cancer Discov
, vol.2
, pp. 881-898
-
-
Cantor, J.R.1
Sabatini, D.M.2
-
16
-
-
84926430176
-
Cancer prevention and therapy through the modulation of the tumor microenvironment
-
Casey, S. C., Amedei, A., Aquilano, K., Azmi, A. S., Benencia, F., Bhakta, D., et al. (2015). Cancer prevention and therapy through the modulation of the tumor microenvironment. Semin. Cancer Biol. 35, S199-S223. doi: 10.1016/j.semcancer.2015.02.007
-
(2015)
Semin. Cancer Biol
, vol.35
, pp. S199-S223
-
-
Casey, S.C.1
Amedei, A.2
Aquilano, K.3
Azmi, A.S.4
Benencia, F.5
Bhakta, D.6
-
17
-
-
84875208817
-
The effect of carbohydrate restriction on prostate cancer tumor growth in a castrate mouse xenograft model
-
Caso, J., Masko, E. M., Ii, J. A., Poulton, S. H., Dewhirst, M., Pizzo, S. V., et al. (2013). The effect of carbohydrate restriction on prostate cancer tumor growth in a castrate mouse xenograft model. Prostate 73, 449-454. doi: 10.1002/pros.22586
-
(2013)
Prostate
, vol.73
, pp. 449-454
-
-
Caso, J.1
Masko, E.M.2
Ii, J.A.3
Poulton, S.H.4
Dewhirst, M.5
Pizzo, S.V.6
-
18
-
-
84873037371
-
Nutrient restriction and radiation therapy for cancer treatment: When less is more
-
Champ, C. E., Baserga, R., Mishra, M. V., Jin, L., Sotgia, F., Lisanti, M. P., et al. (2013). Nutrient restriction and radiation therapy for cancer treatment: when less is more. Oncologist 18, 97-103. doi: 10.1634/theoncologist.2012-0164
-
(2013)
Oncologist
, vol.18
, pp. 97-103
-
-
Champ, C.E.1
Baserga, R.2
Mishra, M.V.3
Jin, L.4
Sotgia, F.5
Lisanti, M.P.6
-
19
-
-
84901625233
-
Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme
-
Champ, C. E., Palmer, J. D., Volek, J. S., Werner-Wasik, M., Andrews, D. W., Evans, J. J., et al. (2014). Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme. J. Neurooncol. 117, 125-131. doi: 10.1007/s11060-014-1362-0
-
(2014)
J. Neurooncol
, vol.117
, pp. 125-131
-
-
Champ, C.E.1
Palmer, J.D.2
Volek, J.S.3
Werner-Wasik, M.4
Andrews, D.W.5
Evans, J.J.6
-
20
-
-
84920059831
-
The emerging roles of microRNAs in cancer metabolism
-
Chan, B., Manley, J., Lee, J., and Singh, S. R. (2015). The emerging roles of microRNAs in cancer metabolism. Cancer Lett. 356, 301-308. doi: 10.1016/j.canlet.2014.10.011
-
(2015)
Cancer Lett
, vol.356
, pp. 301-308
-
-
Chan, B.1
Manley, J.2
Lee, J.3
Singh, S.R.4
-
21
-
-
84973494141
-
Emerging approaches for targeting metabolic vulnerabilities in malignant glioma
-
Clark, P. M., Mai, W. X., Cloughesy, T. F., and Nathanson, D. A. (2016). Emerging approaches for targeting metabolic vulnerabilities in malignant glioma. Curr. Neurol. Neurosci. Rep. 16:17. doi: 10.1007/s11910-015-0613-6
-
(2016)
Curr. Neurol. Neurosci. Rep
, vol.16
, pp. 17
-
-
Clark, P.M.1
Mai, W.X.2
Cloughesy, T.F.3
Nathanson, D.A.4
-
22
-
-
84942786804
-
Metabolic and mind shifts: From glucose to glutamine and acetate addictions in cancer
-
Corbet, C., and Feron, O. (2015). Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer. Curr. Opin. Clin. Nutr. Metab. Care 18, 346-353. doi: 10.1097/MCO.0000000000000178
-
(2015)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.18
, pp. 346-353
-
-
Corbet, C.1
Feron, O.2
-
23
-
-
84930277289
-
Cancer metabolism and the Warburg effect: The role of HIF-1 and PI3K
-
Courtnay, R., Ngo, D. C., Malik, N., Ververis, K., Tortorella, S. M., and Karagiannis, T. C. (2015). Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K. Mol. Biol. Rep. 42, 841-851. doi: 10.1007/s11033-015-3858-x
-
(2015)
Mol. Biol. Rep
, vol.42
, pp. 841-851
-
-
Courtnay, R.1
Ngo, D.C.2
Malik, N.3
Ververis, K.4
Tortorella, S.M.5
Karagiannis, T.C.6
-
24
-
-
84880826654
-
New research with diets and epilepsy
-
Cross, J. H. (2013). New research with diets and epilepsy. J. Child Neurol. 28, 970-974. doi: 10.1177/0883073813487593
-
(2013)
J. Child Neurol
, vol.28
, pp. 970-974
-
-
Cross, J.H.1
-
25
-
-
84883508982
-
Optimization of tumor radiotherapy with modulators of cell metabolism: Toward clinical applications
-
Danhier, P., De Saedeleer, C. J., Karroum, O., De Preter, G., Porporato, P. E., Jordan, B. F., et al. (2013). Optimization of tumor radiotherapy with modulators of cell metabolism: toward clinical applications. Semin. Radiat. Oncol. 23, 262-272. doi: 10.1016/j.semradonc.2013.05.008
-
(2013)
Semin. Radiat. Oncol
, vol.23
, pp. 262-272
-
-
Danhier, P.1
De Saedeleer, C.J.2
Karroum, O.3
De Preter, G.4
Porporato, P.E.5
Jordan, B.F.6
-
26
-
-
70549102512
-
Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress
-
Dewhirst, M. W. (2009). Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress. Radiat. Res. 172, 653-665. doi: 10.1667/RR1926.1
-
(2009)
Radiat. Res
, vol.172
, pp. 653-665
-
-
Dewhirst, M.W.1
-
27
-
-
84940467267
-
Regulation of mTORC1 by PI3K signaling
-
Dibble, C. C., and Cantley, L. C. (2015). Regulation of mTORC1 by PI3K signaling. Trends Cell Biol. 25, 545-555. doi: 10.1016/j.tcb.2015.06.002
-
(2015)
Trends Cell Biol
, vol.25
, pp. 545-555
-
-
Dibble, C.C.1
Cantley, L.C.2
-
28
-
-
84922268466
-
The level of patient-reported outcome reporting in randomised controlled trials of brain tumour patients: A systematic review
-
Dirven, L., Taphoorn, M. J., Reijneveld, J. C., Blazeby, J., Jacobs, M., Pusic, A., et al. (2014). The level of patient-reported outcome reporting in randomised controlled trials of brain tumour patients: a systematic review. Eur. J. Cancer 50, 2432-2448. doi: 10.1016/j.ejca.2014.06.016
-
(2014)
Eur. J. Cancer
, vol.50
, pp. 2432-2448
-
-
Dirven, L.1
Taphoorn, M.J.2
Reijneveld, J.C.3
Blazeby, J.4
Jacobs, M.5
Pusic, A.6
-
29
-
-
0023877369
-
Cancer cachexia: Influence of systemic ketosis on substrate levels and nitrogen metabolism
-
Fearon, K. C., Borland, W., Preston, T., Tisdale, M. J., Shenkin, A., and Calman, K. C. (1988). Cancer cachexia: influence of systemic ketosis on substrate levels and nitrogen metabolism. Am. J. Clin. Nutr. 47, 42-48.
-
(1988)
Am. J. Clin. Nutr
, vol.47
, pp. 42-48
-
-
Fearon, K.C.1
Borland, W.2
Preston, T.3
Tisdale, M.J.4
Shenkin, A.5
Calman, K.C.6
-
30
-
-
0036354737
-
Hypoxia-induced hyperpermeability in brain microvessel endothelial cells involves VEGF-mediated changes in the expression of zonula occludens-1
-
Fischer, S., Wobben, M., Marti, H. H., Renz, D., and Schaper, W. (2002). Hypoxia-induced hyperpermeability in brain microvessel endothelial cells involves VEGF-mediated changes in the expression of zonula occludens-1. Microvasc. Res. 63, 70-80. doi: 10.1006/mvre.2001.2367
-
(2002)
Microvasc. Res
, vol.63
, pp. 70-80
-
-
Fischer, S.1
Wobben, M.2
Marti, H.H.3
Renz, D.4
Schaper, W.5
-
31
-
-
37449034484
-
Carbohydrate restriction, prostate cancer growth and the insulin-like growth factor axis
-
Freedland, S. J., Mavropoulos, J., Wang, A., Darshan, M., Demark-Wahnefried, W., Aronson, W. J., et al. (2008). Carbohydrate restriction, prostate cancer growth and the insulin-like growth factor axis. Prostate 68, 11-19. doi: 10.1002/pros.20683
-
(2008)
Prostate
, vol.68
, pp. 11-19
-
-
Freedland, S.J.1
Mavropoulos, J.2
Wang, A.3
Darshan, M.4
Demark-Wahnefried, W.5
Aronson, W.J.6
-
32
-
-
34247847903
-
Silencing hypoxia-inducible factor-1α inhibits cell migration and invasion under hypoxic environment in malignant gliomas
-
Fujiwara, S., Nakagawa, K., Harada, H., Nagato, S., Furukawa, K., Teraoka, M., et al. (2007). Silencing hypoxia-inducible factor-1α inhibits cell migration and invasion under hypoxic environment in malignant gliomas. Int. J. Oncol. 30, 793-802. doi: 10.3892/ijo.30.4.793
-
(2007)
Int. J. Oncol
, vol.30
, pp. 793-802
-
-
Fujiwara, S.1
Nakagawa, K.2
Harada, H.3
Nagato, S.4
Furukawa, K.5
Teraoka, M.6
-
33
-
-
84965191205
-
Ketogenic diets, mitochondria and neurological diseases
-
Gano, L. B., Patel, M., and Rho, J. M. (2014). Ketogenic diets, mitochondria and neurological diseases. J. Lipid Res. 55, 2211-2228. doi: 10.1194/jlr.r048975
-
(2014)
J. Lipid Res
, vol.55
, pp. 2211-2228
-
-
Gano, L.B.1
Patel, M.2
Rho, J.M.3
-
34
-
-
33748298884
-
Neuroprotective and disease-modifying effects of the ketogenic diet
-
Gasior, M., Rogawski, M. A., and Hartman, A. L. (2006). Neuroprotective and disease-modifying effects of the ketogenic diet. Behav. Pharmacol. 17, 431-439. doi: 10.1097/00008877-200609000-00009
-
(2006)
Behav. Pharmacol
, vol.17
, pp. 431-439
-
-
Gasior, M.1
Rogawski, M.A.2
Hartman, A.L.3
-
35
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby, R. A., and Gillies, R. J. (2004). Why do cancers have high aerobic glycolysis? Nat. Rev. Cancer 4, 891-899. doi: 10.1038/nrc1478
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
36
-
-
85069238576
-
Defects in mitochondrial metabolism and cancer
-
Gaude, E., and Frezza, C. (2014). Defects in mitochondrial metabolism and cancer. Cancer Metab. 2:10. doi: 10.1186/2049-3002-2-10
-
(2014)
Cancer Metab
, vol.2
, pp. 10
-
-
Gaude, E.1
Frezza, C.2
-
37
-
-
84917710704
-
Long-chain Fatty Acid analogues suppress breast tumorigenesis and progression
-
Gluschnaider, U., Hertz, R., Ohayon, S., Smeir, E., Smets, M., Pikarsky, E., et al. (2014). Long-chain Fatty Acid analogues suppress breast tumorigenesis and progression. Cancer Res. 74, 6991-7002. doi: 10.1158/0008-5472.CAN-14-0385
-
(2014)
Cancer Res
, vol.74
, pp. 6991-7002
-
-
Gluschnaider, U.1
Hertz, R.2
Ohayon, S.3
Smeir, E.4
Smets, M.5
Pikarsky, E.6
-
38
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D., and Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell 144, 646-674. doi: 10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
39
-
-
84928574381
-
Growth of human colon cancer cells in nude mice is delayed by ketogenic diet with or without omega-3 fatty acids and medium-chain triglycerides. Asian Pac
-
Hao, G. W., Chen, Y. S., He, D. M., Wang, H. Y., Wu, G. H., and Zhang, B. (2015). Growth of human colon cancer cells in nude mice is delayed by ketogenic diet with or without omega-3 fatty acids and medium-chain triglycerides. Asian Pac. J. Cancer Prev. 16, 2061-2068. doi: 10.7314/apjcp.2015.16.5.2061
-
(2015)
J. Cancer Prev
, vol.16
, pp. 2061-2068
-
-
Hao, G.W.1
Chen, Y.S.2
He, D.M.3
Wang, H.Y.4
Wu, G.H.5
Zhang, B.6
-
40
-
-
84864080763
-
Neuroprotection in metabolism-based therapy
-
Hartman, A. L. (2012). Neuroprotection in metabolism-based therapy. Epilepsy Res. 100, 286-294. doi: 10.1016/j.eplepsyres.2011.04.016
-
(2012)
Epilepsy Res
, vol.100
, pp. 286-294
-
-
Hartman, A.L.1
-
41
-
-
84856302564
-
Bevacizumab impairs oxidative energy metabolism and shows antitumoral effects in recurrent glioblastomas: A 31P/1H MRSI and quantitative magnetic resonance imaging study
-
Hattingen, E., Jurcoane, A., Bähr, O., Rieger, J., Magerkurth, J., Anti, S., et al. (2011). Bevacizumab impairs oxidative energy metabolism and shows antitumoral effects in recurrent glioblastomas: a 31P/1H MRSI and quantitative magnetic resonance imaging study. Neuro Oncol. 13, 1349-1363. doi: 10.1093/neuonc/nor132
-
(2011)
Neuro Oncol
, vol.13
, pp. 1349-1363
-
-
Hattingen, E.1
Jurcoane, A.2
Bähr, O.3
Rieger, J.4
Magerkurth, J.5
Anti, S.6
-
42
-
-
34948866776
-
Regulation and function of aquaporin-1 in glioma cells
-
Hayashi, Y., Edwards, N. A., Proescholdt, M. A., Oldfield, E. H., and Merrill, M. J. (2007). Regulation and function of aquaporin-1 in glioma cells. Neoplasia 9, 777-787. doi: 10.1593/neo.07454
-
(2007)
Neoplasia
, vol.9
, pp. 777-787
-
-
Hayashi, Y.1
Edwards, N.A.2
Proescholdt, M.A.3
Oldfield, E.H.4
Merrill, M.J.5
-
43
-
-
38049016464
-
Caloric restriction and genomic stability
-
Heydari, A. R., Unnikrishnan, A., Lucente, L. V., and Richardson, A. (2007). Caloric restriction and genomic stability. Nucleic Acids Res. 35, 7485-7496. doi: 10.1093/nar/gkm860
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7485-7496
-
-
Heydari, A.R.1
Unnikrishnan, A.2
Lucente, L.V.3
Richardson, A.4
-
44
-
-
84875356074
-
Regulation of the metabolism of polyunsaturated Fatty acids and butyrate in colon cancer cells
-
Hofmanova, J., Hyrslova Vaculova, A., and Kozubik, A. (2013). Regulation of the metabolism of polyunsaturated Fatty acids and butyrate in colon cancer cells. Curr. Pharm. Biotechnol. 14, 274-288. doi: 10.2174/1389201011314030004
-
(2013)
Curr. Pharm. Biotechnol
, vol.14
, pp. 274-288
-
-
Hofmanova, J.1
Hyrslova Vaculova, A.2
Kozubik, A.3
-
45
-
-
84862762917
-
The “go or grow” potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase
-
Horing, E., Harter, P. N., Seznec, J., Schittenhelm, J., Buhring, H. J., Bhattacharyya, S., et al. (2012). The “go or grow” potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress. Acta Neuropathol. 124, 83-97. doi: 10.1007/s00401-011-0940-x
-
(2012)
E and Mediated by Metabolic Stress. Acta Neuropathol
, vol.124
, pp. 83-97
-
-
Horing, E.1
Harter, P.N.2
Seznec, J.3
Schittenhelm, J.4
Buhring, H.J.5
Bhattacharyya, S.6
-
46
-
-
84947937089
-
MYC and metabolism on the path to cancer
-
Hsieh, A. L., Walton, Z. E., Altman, B. J., Stine, Z. E., and Dang, C. V. (2015). MYC and metabolism on the path to cancer. Semin. Cell Dev. Biol. 43, 11-21. doi: 10.1016/j.semcdb.2015.08.003
-
(2015)
Semin. Cell Dev. Biol
, vol.43
, pp. 11-21
-
-
Hsieh, A.L.1
Walton, Z.E.2
Altman, B.J.3
Stine, Z.E.4
Dang, C.V.5
-
47
-
-
84880648196
-
Tumor-derived lactate modifies antitumor immune response: Effect on myeloid-derived suppressor cells and NK cells
-
Husain, Z., Huang, Y., Seth, P., and Sukhatme, V. P. (2013). Tumor-derived lactate modifies antitumor immune response: effect on myeloid-derived suppressor cells and NK cells. J. Immunol. 191, 1486-1495. doi: 10.4049/jimmunol.1202702
-
(2013)
J. Immunol
, vol.191
, pp. 1486-1495
-
-
Husain, Z.1
Huang, Y.2
Seth, P.3
Sukhatme, V.P.4
-
48
-
-
84901428396
-
Regulation of cancer metabolism by oncogenes and tumor suppressors
-
Iurlaro, R., León-Annicchiarico, C. L., and Muñoz-Pinedo, C. (2014). Regulation of cancer metabolism by oncogenes and tumor suppressors. Methods Enzymol. 542, 59-80. doi: 10.1016/B978-0-12-416618-9.00003-0
-
(2014)
Methods Enzymol
, vol.542
, pp. 59-80
-
-
Iurlaro, R.1
León-Annicchiarico, C.L.2
Muñoz-Pinedo, C.3
-
49
-
-
84955321102
-
Acetate as a metabolic and epigenetic modifier of cancer therapy
-
Jaworski, D. M., Namboodiri, A. M., and Moffett, J. R. (2016). Acetate as a metabolic and epigenetic modifier of cancer therapy. J. Cell. Biochem. 117, 574-588. doi: 10.1002/jcb.25305
-
(2016)
J. Cell. Biochem
, vol.117
, pp. 574-588
-
-
Jaworski, D.M.1
Namboodiri, A.M.2
Moffett, J.R.3
-
50
-
-
84881171944
-
Caloric restriction reduces edema and prolongs survival in a mouse glioma model
-
Jiang, Y.-S., and Wang, F.-R. (2013). Caloric restriction reduces edema and prolongs survival in a mouse glioma model. J. Neurooncol. 114, 25-32. doi: 10.1007/s11060-013-1154-y
-
(2013)
J. Neurooncol
, vol.114
, pp. 25-32
-
-
Jiang, Y.-S.1
Wang, F.-R.2
-
51
-
-
3242811307
-
Tumors may modulate host immunity partly through hypoxia-induced sympathetic bias
-
Joon, Y. A., Bazar, K. A., and Lee, P. Y. (2004). Tumors may modulate host immunity partly through hypoxia-induced sympathetic bias. Med. Hypotheses 63, 352-356. doi: 10.1016/j.mehy.2004.02.026
-
(2004)
Med. Hypotheses
, vol.63
, pp. 352-356
-
-
Joon, Y.A.1
Bazar, K.A.2
Lee, P.Y.3
-
52
-
-
84929353032
-
Molecular connections between cancer cell metabolism and the tumor microenvironment
-
Justus, C. R., Sanderlin, E. J., and Yang, L. V. (2015). Molecular connections between cancer cell metabolism and the tumor microenvironment. Int. J. Mol. Sci. 16, 11055-11086. doi: 10.3390/ijms160511055
-
(2015)
Int. J. Mol. Sci
, vol.16
, pp. 11055-11086
-
-
Justus, C.R.1
Sanderlin, E.J.2
Yang, L.V.3
-
53
-
-
84875253158
-
A ketone ester diet exhibits anxiolytic and cognition-sparing properties and lessens amyloid and tau pathologies in a mouse model of Alzheimer’s disease
-
Kashiwaya, Y., Bergman, C., Lee, J. H., Wan, R., King, M. T., Mughal, M. R., et al. (2013). A ketone ester diet exhibits anxiolytic and cognition-sparing properties and lessens amyloid and tau pathologies in a mouse model of Alzheimer’s disease. Neurobiol. Aging 34, 1530-1539. doi: 10.1016/j.neurobiolaging.2012.11.023
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 1530-1539
-
-
Kashiwaya, Y.1
Bergman, C.2
Lee, J.H.3
Wan, R.4
King, M.T.5
Mughal, M.R.6
-
54
-
-
17844371306
-
Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis
-
Kaur, B., Khwaja, F. W., Severson, E. A., Matheny, S. L., Brat, D. J., and Van Meir, E. G. (2005). Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro Oncol. 7, 134-153. doi: 10.1215/s1152851704001115
-
(2005)
Neuro Oncol
, vol.7
, pp. 134-153
-
-
Kaur, B.1
Khwaja, F.W.2
Severson, E.A.3
Matheny, S.L.4
Brat, D.J.5
Van Meir, E.G.6
-
55
-
-
84860494814
-
Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis
-
Kim, D. Y., Hao, J., Liu, R., Turner, G., Shi, F.-D., and Rho, J. M. (2012). Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis. PLoS One 7:e35476. doi: 10.1371/journal.pone.0035476
-
(2012)
Plos One
, vol.7
-
-
Kim, D.Y.1
Hao, J.2
Liu, R.3
Turner, G.4
Shi, F.-D.5
Rho, J.M.6
-
56
-
-
84871706742
-
Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer
-
Kim, H. S., Masko, E. M., Poulton, S. L., Kennedy, K. M., Pizzo, S. V., Dewhirst, M. W., et al. (2012). Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer. BJU Int. 110, 1062-1069. doi: 10.1111/j.1464-410x.2012.10971.x
-
(2012)
BJU Int
, vol.110
, pp. 1062-1069
-
-
Kim, H.S.1
Masko, E.M.2
Poulton, S.L.3
Kennedy, K.M.4
Pizzo, S.V.5
Dewhirst, M.W.6
-
57
-
-
84930652884
-
Oncogenes and tumor suppressors regulate glutamine metabolism in cancer cells
-
Kim, M. H., and Kim, H. (2013). Oncogenes and tumor suppressors regulate glutamine metabolism in cancer cells. J. Cancer Prev. 18, 221-226. doi: 10.15430/jcp.2013.18.3.221
-
(2013)
J. Cancer Prev
, vol.18
, pp. 221-226
-
-
Kim, M.H.1
Kim, H.2
-
58
-
-
40049107581
-
The ketogenic diet and epilepsy
-
Kim, D. Y., and Rho, J. M. (2008). The ketogenic diet and epilepsy. Curr. Opin. Clin. Nutr. Metab. Care 11, 113-120. doi: 10.1097/MCO.0b013e3282f44c06
-
(2008)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.11
, pp. 113-120
-
-
Kim, D.Y.1
Rho, J.M.2
-
59
-
-
84899977976
-
Calories, carbohydrates and cancer therapy with radiation: Exploiting the five R’s through dietary manipulation
-
Klement, R. J., and Champ, C. E. (2014). Calories, carbohydrates and cancer therapy with radiation: exploiting the five R’s through dietary manipulation. Cancer Metastasis Rev. 33, 217-229. doi: 10.1007/s10555-014-9495-3
-
(2014)
Cancer Metastasis Rev
, vol.33
, pp. 217-229
-
-
Klement, R.J.1
Champ, C.E.2
-
60
-
-
84863229916
-
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
-
Lee, C., Raffaghello, L., Brandhorst, S., Safdie, F. M., Bianchi, G., Martin-Montalvo, A., et al. (2012). Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci. Transl. Med. 4:124ra127. doi: 10.1126/scitranslmed.3003293
-
(2012)
Sci. Transl. Med
-
-
Lee, C.1
Raffaghello, L.2
Brandhorst, S.3
Safdie, F.M.4
Bianchi, G.5
Martin-Montalvo, A.6
-
61
-
-
76749169812
-
Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index
-
Lee, C., Safdie, F. M., Raffaghello, L., Wei, M., Madia, F., Parrella, E., et al. (2010). Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index. Cancer Res. 70, 1564-1572. doi: 10.1158/0008-5472.CAN-09-3228
-
(2010)
Cancer Res
, vol.70
, pp. 1564-1572
-
-
Lee, C.1
Safdie, F.M.2
Raffaghello, L.3
Wei, M.4
Madia, F.5
Parrella, E.6
-
62
-
-
84884565153
-
The evolution of genome-scale models of cancer metabolism. Front
-
Lewis, N. E., and Abdel-Haleem, A. M. (2013). The evolution of genome-scale models of cancer metabolism. Front. Physiol. 4:237. doi: 10.3389/fphys.2013.00237
-
(2013)
Physiol
, vol.4
, pp. 237
-
-
Lewis, N.E.1
Abdel-Haleem, A.M.2
-
63
-
-
67449116585
-
Availability of neurotransmitter glutamate is diminished when β-hydroxybutyrate replaces glucose in cultured neurons
-
Lund, T. M., Risa, O., Sonnewald, U., Schousboe, A., and Waagepetersen, H. S. (2009). Availability of neurotransmitter glutamate is diminished when β-hydroxybutyrate replaces glucose in cultured neurons. J. Neurochem. 110, 80-91. doi: 10.1111/j.1471-4159.2009.06115.x
-
(2009)
J. Neurochem
, vol.110
, pp. 80-91
-
-
Lund, T.M.1
Risa, O.2
Sonnewald, U.3
Schousboe, A.4
Waagepetersen, H.S.5
-
64
-
-
85007454066
-
Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet
-
Lussier, D. M., Woolf, E. C., Johnson, J. L., Brooks, K. S., Blattman, J. N., and Scheck, A. C. (2016). Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet. BMC Cancer 16:310. doi: 10.1186/s12885-016-2337-7
-
(2016)
BMC Cancer
, vol.16
, pp. 310
-
-
Lussier, D.M.1
Woolf, E.C.2
Johnson, J.L.3
Brooks, K.S.4
Blattman, J.N.5
Scheck, A.C.6
-
65
-
-
84918531944
-
Roles of caloric restriction, ketogenic diet and intermittent fasting during initiation, progression and metastasis of cancer in animal models: A systematic review and meta-analysis
-
Lv, M., Zhu, X., Wang, H., Wang, F., and Guan, W. (2014). Roles of caloric restriction, ketogenic diet and intermittent fasting during initiation, progression and metastasis of cancer in animal models: a systematic review and meta-analysis. PLoS One 9:e115147. doi: 10.1371/journal.pone.0115147
-
(2014)
Plos One
, vol.9
-
-
Lv, M.1
Zhu, X.2
Wang, H.3
Wang, F.4
Guan, W.5
-
66
-
-
60749090581
-
The neuroprotective properties of calorie restriction, the ketogenic diet and ketone bodies
-
Maalouf, M., Rho, J. M., and Mattson, M. P. (2009). The neuroprotective properties of calorie restriction, the ketogenic diet and ketone bodies. Brain Res. Rev. 59, 293-315. doi: 10.1016/j.brainresrev.2008.09.002
-
(2009)
Brain Res. Rev
, vol.59
, pp. 293-315
-
-
Maalouf, M.1
Rho, J.M.2
Mattson, M.P.3
-
67
-
-
84862977182
-
Regulation of glucose metabolism by p53: Emerging new roles for the tumor suppressor
-
Madan, E., Gogna, R., Bhatt, M., Pati, U., Kuppusamy, P., and Mahdi, A. A. (2011). Regulation of glucose metabolism by p53: emerging new roles for the tumor suppressor. Oncotarget 2, 948-957. doi: 10.18632/oncotarget.389
-
(2011)
Oncotarget
, vol.2
, pp. 948-957
-
-
Madan, E.1
Gogna, R.2
Bhatt, M.3
Pati, U.4
Kuppusamy, P.5
Mahdi, A.A.6
-
68
-
-
79960858482
-
Metabolism and brain cancer
-
Marie, S. K., and Shinjo, S. M. (2011). Metabolism and brain cancer. Clinics 66, 33-43. doi: 10.1590/s1807-59322011001300005
-
(2011)
Clinics
, vol.66
, pp. 33-43
-
-
Marie, S.K.1
Shinjo, S.M.2
-
69
-
-
58149161852
-
Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet
-
Marsh, J., Mukherjee, P., and Seyfried, T. N. (2008). Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet. Nutr. Metab. (Lond) 5:33. doi: 10.1186/1743-7075-5-33
-
(2008)
Nutr. Metab. (Lond)
, vol.5
, pp. 33
-
-
Marsh, J.1
Mukherjee, P.2
Seyfried, T.N.3
-
70
-
-
84907063686
-
PI3K/AKT signaling pathway and cancer: An updated review
-
Martini, M., De Santis, M. C., Braccini, L., Gulluni, F., and Hirsch, E. (2014). PI3K/AKT signaling pathway and cancer: an updated review. Ann. Med. 46, 372-383. doi: 10.3109/07853890.2014.912836
-
(2014)
Ann. Med
, vol.46
, pp. 372-383
-
-
Martini, M.1
De Santis, M.C.2
Braccini, L.3
Gulluni, F.4
Hirsch, E.5
-
71
-
-
84968735483
-
A supplemented high-fat low-carbohydrate diet for the treatment of glioblastoma
-
Martuscello, R. T., Vedam-Mai, V., McCarthy, D. J., Schmoll, M. E., Jundi, M. A., Louviere, C. D., et al. (2016). A supplemented high-fat low-carbohydrate diet for the treatment of glioblastoma. Clin. Cancer Res. 22, 2482-2495. doi: 10.1158/1078-0432.CCR-15-0916
-
(2016)
Clin. Cancer Res
, vol.22
, pp. 2482-2495
-
-
Martuscello, R.T.1
Vedam-Mai, V.2
McCarthy, D.J.3
Schmoll, M.E.4
Jundi, M.A.5
Louviere, C.D.6
-
72
-
-
84880842042
-
Ketogenic diets and pain
-
Masino, S. A., and Ruskin, D. N. (2013). Ketogenic diets and pain. J. Child Neurol. 28, 993-1001. doi: 10.1177/0883073813487595
-
(2013)
J. Child Neurol
, vol.28
, pp. 993-1001
-
-
Masino, S.A.1
Ruskin, D.N.2
-
73
-
-
84970919297
-
Hypoxia signaling pathways in cancer metabolism: The importance of co-selecting interconnected physiological pathways
-
Masson, N., and Ratcliffe, P. J. (2014). Hypoxia signaling pathways in cancer metabolism: the importance of co-selecting interconnected physiological pathways. Cancer Metab. 2:3. doi: 10.1186/2049-3002-2-3
-
(2014)
Cancer Metab
, vol.2
, pp. 3
-
-
Masson, N.1
Ratcliffe, P.J.2
-
74
-
-
79960661966
-
Differential utilization of ketone bodies by neurons and glioma cell lines: A rationale for ketogenic diet as experimental glioma therapy
-
Maurer, G. D., Brucker, D. P., Bähr, O., Harter, P. N., Hattingen, E., Walenta, S., et al. (2011). Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy. BMC Cancer 11:315. doi: 10.1186/1471-2407-11-315
-
(2011)
BMC Cancer
, vol.11
, pp. 315
-
-
Maurer, G.D.1
Brucker, D.P.2
Bähr, O.3
Harter, P.N.4
Hattingen, E.5
Walenta, S.6
-
75
-
-
68949183226
-
The effects of varying dietary carbohydrate and fat content on survival in a murine LNCaP prostate cancer xenograft model
-
Mavropoulos, J. C., Buschemeyer, W. C. III, Tewari, A. K., Rokhfeld, D., Pollak, M., Zhao, Y., et al. (2009). The effects of varying dietary carbohydrate and fat content on survival in a murine LNCaP prostate cancer xenograft model. Cancer Prev. Res. (Phila) 2, 557-565. doi: 10.1158/1940-6207.capr-08-0188
-
(2009)
Cancer Prev. Res. (Phila)
, vol.2
, pp. 557-565
-
-
Mavropoulos, J.C.1
Buschemeyer, W.2
Tewari, A.K.3
Rokhfeld, D.4
Pollak, M.5
Zhao, Y.6
-
76
-
-
84856014884
-
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
-
Metallo, C. M., Gameiro, P. A., Bell, E. L., Mattaini, K. R., Yang, J., Hiller, K., et al. (2011). Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. Nature 481, 380-384. doi: 10.1038/nature10602
-
(2011)
Nature
, vol.481
, pp. 380-384
-
-
Metallo, C.M.1
Gameiro, P.A.2
Bell, E.L.3
Mattaini, K.R.4
Yang, J.5
Hiller, K.6
-
77
-
-
84864084943
-
Modulation of oxidative stress and mitochondrial function by the ketogenic diet
-
Milder, J., and Patel, M. (2012). Modulation of oxidative stress and mitochondrial function by the ketogenic diet. Epilepsy Res. 100, 295-303. doi: 10.1016/j.eplepsyres.2011.09.021
-
(2012)
Epilepsy Res
, vol.100
, pp. 295-303
-
-
Milder, J.1
Patel, M.2
-
78
-
-
84867540151
-
C-Myc and cancer metabolism
-
Miller, D. M., Thomas, S. D., Islam, A., Muench, D., and Sedoris, K. (2012). c-Myc and cancer metabolism. Clin. Cancer Res. 18, 5546-5553. doi: 10.1158/1078-0432.CCR-12-0977
-
(2012)
Clin. Cancer Res
, vol.18
, pp. 5546-5553
-
-
Miller, D.M.1
Thomas, S.D.2
Islam, A.3
Muench, D.4
Sedoris, K.5
-
79
-
-
84961677958
-
T cells and cancer: How metabolism shapes immunity. Front
-
Molon, B., Cali, B., and Viola, A. (2016). T cells and cancer: how metabolism shapes immunity. Front. Immunol. 7:20. doi: 10.3389/fimmu.2016.00020
-
(2016)
Immunol
, vol.7
, pp. 20
-
-
Molon, B.1
Cali, B.2
Viola, A.3
-
80
-
-
19444376784
-
Cerebral ketone body metabolism
-
Morris, A. A. M. (2005). Cerebral ketone body metabolism. J. Inherit. Metab. Dis. 28, 109-121. doi: 10.1007/s10545-005-5518-0
-
(2005)
J. Inherit. Metab. Dis
, vol.28
, pp. 109-121
-
-
Morris, A.A.M.1
-
81
-
-
78449278861
-
AQP-4 in peritumoral edematous tissue is correlated with the degree of glioma and with expression of VEGF and HIF-alpha
-
Mou, K., Chen, M., Mao, Q., Wang, P., Ni, R., Xia, X., et al. (2010). AQP-4 in peritumoral edematous tissue is correlated with the degree of glioma and with expression of VEGF and HIF-alpha. J. Neurooncol. 100, 375-383. doi: 10.1007/s11060-010-0205-x
-
(2010)
J. Neurooncol
, vol.100
, pp. 375-383
-
-
Mou, K.1
Chen, M.2
Mao, Q.3
Wang, P.4
Ni, R.5
Xia, X.6
-
82
-
-
0029009816
-
Implementing a ketogenic diet based on medium-chain triglyceride oil in pediatric patients with cancer
-
Nebeling, L. C., and Lerner, E. (1995). Implementing a ketogenic diet based on medium-chain triglyceride oil in pediatric patients with cancer. J. Am. Diet. Assoc. 95, 693-697. doi: 10.1016/s0002-8223(95)00189-1
-
(1995)
J. Am. Diet. Assoc
, vol.95
, pp. 693-697
-
-
Nebeling, L.C.1
Lerner, E.2
-
83
-
-
0028946933
-
Effects of a ketogenic diet on tumor metabolism and nutritional status in pediatric oncology patients: Two case reports
-
Nebeling, L. C., Miraldi, F., Shurin, S. B., and Lerner, E. (1995). Effects of a ketogenic diet on tumor metabolism and nutritional status in pediatric oncology patients: two case reports. J. Am. Coll. Nutr. 14, 202-208. doi: 10.1080/07315724.1995.10718495
-
(1995)
J. Am. Coll. Nutr
, vol.14
, pp. 202-208
-
-
Nebeling, L.C.1
Miraldi, F.2
Shurin, S.B.3
Lerner, E.4
-
84
-
-
84890978770
-
Ketone bodies as signaling metabolites
-
Newman, J. C., and Verdin, E. (2014). Ketone bodies as signaling metabolites. Trends Endocrinol. Metab. 25, 42-52. doi: 10.1016/j.tem.2013.09.002
-
(2014)
Trends Endocrinol. Metab
, vol.25
, pp. 42-52
-
-
Newman, J.C.1
Verdin, E.2
-
85
-
-
84922709891
-
A new way to produce hyperketonemia: Use of ketone ester in a case of Alzheimer’s disease
-
Newport, M. T., Vanitallie, T. B., Kashiwaya, Y., King, M. T., and Veech, R. L. (2015). A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer’s disease. Alzheimers Dement. 11, 99-103. doi: 10.1016/j.jalz.2014.01.006
-
(2015)
Alzheimers Dement
, vol.11
, pp. 99-103
-
-
Newport, M.T.1
Vanitallie, T.B.2
Kashiwaya, Y.3
King, M.T.4
Veech, R.L.5
-
86
-
-
79952947661
-
Molecular heterogeneity in glioblastoma: Therapeutic opportunities and challenges
-
Nicholas, M. K., Lukas, R. V., Chmura, S., Yamini, B., Lesniak, M., and Pytel, P. (2011). Molecular heterogeneity in glioblastoma: therapeutic opportunities and challenges. Semin. Oncol. 38, 243-253. doi: 10.1053/j.seminoncol.2011.01.009
-
(2011)
Semin. Oncol
, vol.38
, pp. 243-253
-
-
Nicholas, M.K.1
Lukas, R.V.2
Chmura, S.3
Yamini, B.4
Lesniak, M.5
Pytel, P.6
-
87
-
-
78651362626
-
Therapeutic options for recurrent malignant glioma
-
Niyazi, M., Siefert, A., Schwarz, S. B., Ganswindt, U., Kreth, F. W., Tonn, J. C., et al. (2011). Therapeutic options for recurrent malignant glioma. Radiother. Oncol. 98, 1-14. doi: 10.1016/j.radonc.2010.11.006
-
(2011)
Radiother. Oncol
, vol.98
, pp. 1-14
-
-
Niyazi, M.1
Siefert, A.2
Schwarz, S.B.3
Ganswindt, U.4
Kreth, F.W.5
Tonn, J.C.6
-
88
-
-
84920814046
-
Emerging concepts in bioenergetics and cancer research: Metabolic flexibility, coupling, symbiosis, switch, oxidative tumors, metabolic remodeling, signaling and bioenergetic therapy
-
Obre, E., and Rossignol, R. (2015). Emerging concepts in bioenergetics and cancer research: metabolic flexibility, coupling, symbiosis, switch, oxidative tumors, metabolic remodeling, signaling and bioenergetic therapy. Int. J. Biochem. Cell Biol. 59C, 167-181. doi: 10.1016/j.biocel.2014.12.008
-
(2015)
Int. J. Biochem. Cell Biol
, vol.59
, pp. 167-181
-
-
Obre, E.1
Rossignol, R.2
-
89
-
-
60249088344
-
Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense
-
Olovnikov, I. A., Kravchenko, J. E., and Chumakov, P. M. (2009). Homeostatic functions of the p53 tumor suppressor: regulation of energy metabolism and antioxidant defense. Semin. Cancer Biol. 19, 32-41. doi: 10.1016/j.semcancer.2008.11.005
-
(2009)
Semin. Cancer Biol
, vol.19
, pp. 32-41
-
-
Olovnikov, I.A.1
Kravchenko, J.E.2
Chumakov, P.M.3
-
90
-
-
44649088303
-
Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides
-
Otto, C., Kaemmerer, U., Illert, B., Muehling, B., Pfetzer, N., Wittig, R., et al. (2008). Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides. BMC Cancer 8:122. doi: 10.1186/1471-2407-8-122
-
(2008)
BMC Cancer
, vol.8
, pp. 122
-
-
Otto, C.1
Kaemmerer, U.2
Illert, B.3
Muehling, B.4
Pfetzer, N.5
Wittig, R.6
-
91
-
-
84955326448
-
The emerging hallmarks of cancer metabolism
-
Pavlova, N. N., and Thompson, C. B. (2016). The emerging hallmarks of cancer metabolism. Cell Metab. 23, 27-47. doi: 10.1016/j.cmet.2015.12.006
-
(2016)
Cell Metab
, vol.23
, pp. 27-47
-
-
Pavlova, N.N.1
Thompson, C.B.2
-
92
-
-
85015692306
-
Abstract 240: The ketogenic diet alters the expression of microRNAs that play key roles in tumor development
-
Pazmandi, J., O’Neill, K. S., Scheck, A. C., Szlosarek, P. W., Woolf, E. C., Brooks, K. S., et al. (2015). Abstract 240: the ketogenic diet alters the expression of microRNAs that play key roles in tumor development. Cancer Res. 75, 240-240. doi: 10.1158/1538-7445.am2015-240
-
(2015)
Cancer Res
, vol.75
, pp. 240-240
-
-
Pazmandi, J.1
O’Neill, K.S.2
Scheck, A.C.3
Szlosarek, P.W.4
Woolf, E.C.5
Brooks, K.S.6
-
93
-
-
84964300029
-
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells
-
Pérez-Escuredo, J., Dadhich, R. K., Dhup, S., Cacace, A., Van Hée, V. F., De Saedeleer, C. J., et al. (2016). Lactate promotes glutamine uptake and metabolism in oxidative cancer cells. Cell Cycle 15, 72-83. doi: 10.1080/15384101.2015.1120930
-
(2016)
Cell Cycle
, vol.15
, pp. 72-83
-
-
Pérez-Escuredo, J.1
Dadhich, R.K.2
Dhup, S.3
Cacace, A.4
Van Hée, V.F.5
De Saedeleer, C.J.6
-
94
-
-
55349122964
-
Ketones and brain function: Possible link to polyunsaturated fatty acids and availability of a new brain PET tracer, 11C-acetoacetate
-
Pifferi, F., Tremblay, S., Plourde, M., Tremblay-Mercier, J., Bentourkia, M., and Cunnane, S. C. (2008). Ketones and brain function: possible link to polyunsaturated fatty acids and availability of a new brain PET tracer, 11C-acetoacetate. Epilepsia 49, 76-79. doi: 10.1111/j.1528-1167.2008.01842.x
-
(2008)
Epilepsia
, vol.49
, pp. 76-79
-
-
Pifferi, F.1
Tremblay, S.2
Plourde, M.3
Tremblay-Mercier, J.4
Bentourkia, M.5
Cunnane, S.C.6
-
95
-
-
84904438541
-
Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer
-
Poff, A. M., Ari, C., Arnold, P., Seyfried, T. N., and D’Agostino, D. P. (2014). Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer. Int. J. Cancer 135, 1711-1720. doi: 10.1002/ijc.28809
-
(2014)
Int. J. Cancer
, vol.135
, pp. 1711-1720
-
-
Poff, A.M.1
Ari, C.2
Arnold, P.3
Seyfried, T.N.4
D’Agostino, D.P.5
-
96
-
-
84878758801
-
The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer
-
Poff, A. M., Ari, C., Seyfried, T. N., and D’Agostino, D. P. (2013). The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer. PLoS One 8:e65522. doi: 10.1371/journal.pone.0065522
-
(2013)
Plos One
, vol.8
-
-
Poff, A.M.1
Ari, C.2
Seyfried, T.N.3
D’Agostino, D.P.4
-
97
-
-
84936976775
-
Non-toxic metabolic management of metastatic cancer in vm mice: Novel combination of ketogenic diet, ketone supplementation and hyperbaric oxygen therapy
-
Poff, A. M., Ward, N., Seyfried, T. N., Arnold, P., and D’Agostino, D. P. (2015). Non-toxic metabolic management of metastatic cancer in vm mice: novel combination of ketogenic diet, ketone supplementation and hyperbaric oxygen therapy. PLoS One 10:e0127407. doi: 10.1371/journal.pone.0127407
-
(2015)
Plos One
, vol.10
-
-
Poff, A.M.1
Ward, N.2
Seyfried, T.N.3
Arnold, P.4
D’Agostino, D.P.5
-
98
-
-
33746899015
-
Akt1 activation can augment hypoxia-inducible factor-1α expression by increasing protein translation through a mammalian target of rapamycin-independent pathway
-
Pore, N., Jiang, Z., Shu, H. K., Bernhard, E., Kao, G. D., and Maity, A. (2006). Akt1 activation can augment hypoxia-inducible factor-1α expression by increasing protein translation through a mammalian target of rapamycin-independent pathway. Mol. Cancer Res. 4, 471-479. doi: 10.1158/1541-7786.mcr-05-0234
-
(2006)
Mol. Cancer Res
, vol.4
, pp. 471-479
-
-
Pore, N.1
Jiang, Z.2
Shu, H.K.3
Bernhard, E.4
Kao, G.D.5
Maity, A.6
-
99
-
-
84868011381
-
Function of carbonic anhydrase IX in glioblastoma multiforme
-
Proescholdt, M. A., Merrill, M. J., Stoerr, E. M., Lohmeier, A., Pohl, F., and Brawanski, A. (2012). Function of carbonic anhydrase IX in glioblastoma multiforme. Neuro Oncol. 14, 1357-1366. doi: 10.1093/neuonc/nos216
-
(2012)
Neuro Oncol
, vol.14
, pp. 1357-1366
-
-
Proescholdt, M.A.1
Merrill, M.J.2
Stoerr, E.M.3
Lohmeier, A.4
Pohl, F.5
Brawanski, A.6
-
100
-
-
56649091297
-
Neuroprotection in diet-induced ketotic rat brain after focal ischemia
-
Puchowicz, M. A., Zechel, J. L., Valerio, J., Emancipator, D. S., Xu, K., Pundik, S., et al. (2008). Neuroprotection in diet-induced ketotic rat brain after focal ischemia. J. Cereb. Blood Flow Metab. 28, 1907-1916. doi: 10.1038/jcbfm.2008.79
-
(2008)
J. Cereb. Blood Flow Metab
, vol.28
, pp. 1907-1916
-
-
Puchowicz, M.A.1
Zechel, J.L.2
Valerio, J.3
Emancipator, D.S.4
Xu, K.5
Pundik, S.6
-
101
-
-
80053036165
-
The role of p53 in metabolic regulation
-
Puzio-Kuter, A. M. (2011). The role of p53 in metabolic regulation. Genes Cancer 2, 385-391. doi: 10.1177/1947601911409738
-
(2011)
Genes Cancer
, vol.2
, pp. 385-391
-
-
Puzio-Kuter, A.M.1
-
102
-
-
46149107882
-
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
-
Raffaghello, L., Lee, C., Safdie, F. M., Wei, M., Madia, F., Bianchi, G., et al. (2008). Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. Proc. Natl. Acad. Sci. U S A 105, 8215-8220. doi: 10.1073/pnas.0708100105
-
(2008)
Proc. Natl. Acad. Sci. U S A
, vol.105
, pp. 8215-8220
-
-
Raffaghello, L.1
Lee, C.2
Safdie, F.M.3
Wei, M.4
Madia, F.5
Bianchi, G.6
-
103
-
-
78649882284
-
Fasting and differential chemotherapy protection in patients
-
Raffaghello, L., Safdie, F., Bianchi, G., Dorff, T., Fontana, L., and Longo, V. D. (2010). Fasting and differential chemotherapy protection in patients. Cell Cycle 9, 4474-4476. doi: 10.4161/cc.9.22.13954
-
(2010)
Cell Cycle
, vol.9
, pp. 4474-4476
-
-
Raffaghello, L.1
Safdie, F.2
Bianchi, G.3
Dorff, T.4
Fontana, L.5
Longo, V.D.6
-
104
-
-
84901325457
-
The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages. Nat
-
Rahman, M., Muhammad, S., Khan, M. A., Chen, H., Ridder, D. A., Müller-Fielitz, H., et al. (2014). The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages. Nat. Commun. 5:3944. doi: 10.1038/ncomms4944
-
(2014)
Commun
, vol.5
, pp. 3944
-
-
Rahman, M.1
Muhammad, S.2
Khan, M.A.3
Chen, H.4
Ridder, D.A.5
Müller-Fielitz, H.6
-
105
-
-
84921887492
-
Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy
-
Roberts, D. J., and Miyamoto, S. (2015). Hexokinase II integrates energy metabolism and cellular protection: akting on mitochondria and TORCing to autophagy. Cell Death Differ. 22, 248-257. doi: 10.1038/cdd.2014.173
-
(2015)
Cell Death Differ
, vol.22
, pp. 248-257
-
-
Roberts, D.J.1
Miyamoto, S.2
-
106
-
-
60549111398
-
Is Akt the “Warburg kinase”?-Akt-energy metabolism interactions and oncogenesis
-
Robey, R. B., and Hay, N. (2009). Is Akt the “Warburg kinase”?-Akt-energy metabolism interactions and oncogenesis. Semin. Cancer Biol. 19, 25-31. doi: 10.1016/j.semcancer.2008.11.010
-
(2009)
Semin. Cancer Biol
, vol.19
, pp. 25-31
-
-
Robey, R.B.1
Hay, N.2
-
107
-
-
84937720481
-
Metabolic reprogramming and dysregulated metabolism: Cause, consequence and/or enabler of environmental carcinogenesis?
-
Robey, R. B., Weisz, J., Kuemmerle, N. B., Salzberg, A. C., Berg, A., Brown, D. G., et al. (2015). Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis? Carcinogenesis 36, S203-S231. doi: 10.1093/carcin/bgv037
-
(2015)
Carcinogenesis
, vol.36
, pp. S203-S231
-
-
Robey, R.B.1
Weisz, J.2
Kuemmerle, N.B.3
Salzberg, A.C.4
Berg, A.5
Brown, D.G.6
-
108
-
-
78649295690
-
Current and emerging molecular targets in glioma
-
Roesler, R., Brunetto, A. T., Abujamra, A. L., de Farias, C. B., Brunetto, A. L., and Schwartsmann, G. (2010). Current and emerging molecular targets in glioma. Expert. Rev Anticancer Ther. 10, 1735-1751. doi: 10.1586/era.10.167
-
(2010)
Expert. Rev Anticancer Ther
, vol.10
, pp. 1735-1751
-
-
Roesler, R.1
Brunetto, A.T.2
Abujamra, A.L.3
De Farias, C.B.4
Brunetto, A.L.5
Schwartsmann, G.6
-
109
-
-
84995975577
-
Abstract 3346: The ketone body β-hydroxybutyrate increases radiosensitivity in glioma cell lines in vitro
-
Rossi, A. P., Woolf, E. C., Brooks, K. S., Fairres, M. J., and Scheck, A. C. (2015). Abstract 3346: the ketone body β-hydroxybutyrate increases radiosensitivity in glioma cell lines in vitro. Cancer Res. 75:3346. doi: 10.1158/1538-7445.am2015-3346
-
(2015)
Cancer Res
, vol.75
, pp. 3346
-
-
Rossi, A.P.1
Woolf, E.C.2
Brooks, K.S.3
Fairres, M.J.4
Scheck, A.C.5
-
110
-
-
84866274799
-
Fasting enhances the response of glioma to chemo-and radiotherapy
-
Safdie, F., Brandhorst, S., Wei, M., Wang, W., Lee, C., Hwang, S., et al. (2012). Fasting enhances the response of glioma to chemo-and radiotherapy. PLoS One 7:e44603. doi: 10.1371/journal.pone.0044603
-
(2012)
Plos One
, vol.7
-
-
Safdie, F.1
Brandhorst, S.2
Wei, M.3
Wang, W.4
Lee, C.5
Hwang, S.6
-
111
-
-
84879390182
-
Caloric restriction augments radiation efficacy in breast cancer
-
Saleh, A. D., Simone, B. A., Palazzo, J., Savage, J. E., Sano, Y., Dan, T., et al. (2013). Caloric restriction augments radiation efficacy in breast cancer. Cell Cycle 12, 1955-1963. doi: 10.4161/cc.25016
-
(2013)
Cell Cycle
, vol.12
, pp. 1955-1963
-
-
Saleh, A.D.1
Simone, B.A.2
Palazzo, J.3
Savage, J.E.4
Sano, Y.5
Dan, T.6
-
112
-
-
84902505887
-
Ionizing radiation-induced DNA damage, response and repair
-
Santivasi, W. L., and Xia, F. (2014). Ionizing radiation-induced DNA damage, response and repair. Antioxid. Redox Signal. 21, 251-259. doi: 10.1089/ars.2013.5668
-
(2014)
Antioxid. Redox Signal
, vol.21
, pp. 251-259
-
-
Santivasi, W.L.1
Xia, F.2
-
113
-
-
34548539093
-
Dietary factors and growth and metabolism in experimental tumors
-
Sauer, L. A., Blask, D. E., and Dauchy, R. T. (2007). Dietary factors and growth and metabolism in experimental tumors. J. Nutr. Biochem. 18, 637-649. doi: 10.1016/j.jnutbio.2006.12.009
-
(2007)
J. Nutr. Biochem
, vol.18
, pp. 637-649
-
-
Sauer, L.A.1
Blask, D.E.2
Dauchy, R.T.3
-
114
-
-
84864108226
-
The ketogenic diet for the treatment of glioma: Insights from genetic profiling
-
Scheck, A. C., Abdelwahab, M. G., Fenton, K., and Stafford, P. (2012). The ketogenic diet for the treatment of glioma: insights from genetic profiling. Epilepsy Res. 100, 327-337. doi: 10.1016/j.eplepsyres.2011.09.022
-
(2012)
Epilepsy Res
, vol.100
, pp. 327-337
-
-
Scheck, A.C.1
Abdelwahab, M.G.2
Fenton, K.3
Stafford, P.4
-
115
-
-
84920519675
-
Abstract 638: Mechanistic studies of the ketogenic diet as an adjuvant therapy for malignant gliomas
-
Scheck, A. C., Abdelwahab, M. G., Stafford, P., Kim, D. Y., Iwai, S., Preul, M. C., et al. (2011). Abstract 638: mechanistic studies of the ketogenic diet as an adjuvant therapy for malignant gliomas. Cancer Res. 70, 638-638. doi: 10.1158/1538-7445.am10-638
-
(2011)
Cancer Res
, vol.70
, pp. 638-638
-
-
Scheck, A.C.1
Abdelwahab, M.G.2
Stafford, P.3
Kim, D.Y.4
Iwai, S.5
Preul, M.C.6
-
116
-
-
79960688044
-
Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial
-
Schmidt, M., Pfetzer, N., Schwab, M., Strauss, I., and Kammerer, U. (2011). Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: a pilot trial. Nutr. Metab. (Lond) 8:54. doi: 10.1186/1743-7075-8-54
-
(2011)
Nutr. Metab. (Lond)
, vol.8
, pp. 54
-
-
Schmidt, M.1
Pfetzer, N.2
Schwab, M.3
Strauss, I.4
Kammerer, U.5
-
117
-
-
84930937889
-
Treatment of glioma patients with ketogenic diets: Report of two cases treated with an IRB-approved energy-restricted ketogenic diet protocol and review of the literature
-
Schwartz, K., Chang, H. T., Nikolai, M., Pernicone, J., Rhee, S., Olson, K., et al. (2015). Treatment of glioma patients with ketogenic diets: report of two cases treated with an IRB-approved energy-restricted ketogenic diet protocol and review of the literature. Cancer Metab. 3:3. doi: 10.1186/s40170-015-0129-1
-
(2015)
Cancer Metab
, vol.3
, pp. 3
-
-
Schwartz, K.1
Chang, H.T.2
Nikolai, M.3
Pernicone, J.4
Rhee, S.5
Olson, K.6
-
118
-
-
84883501150
-
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
-
Semenza, G. L. (2013). HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations. J. Clin. Invest 123, 3664-3671. doi: 10.1172/JCI67230
-
(2013)
J. Clin. Invest
, vol.123
, pp. 3664-3671
-
-
Semenza, G.L.1
-
119
-
-
84891585156
-
-
Management and Prevention of Cancer. Hoboken, NJ: John Wiley and Sons, Inc
-
Seyfried, T. N. (2012). Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer. Hoboken, NJ: John Wiley and Sons, Inc.
-
(2012)
Cancer as a Metabolic Disease: On the Origin
-
-
Seyfried, T.N.1
-
120
-
-
79955598077
-
Metabolic management of brain cancer
-
Seyfried, T. N., Kiebish, M. A., Marsh, J., Shelton, L. M., Huysentruyt, L. C., and Mukherjee, P. (2011). Metabolic management of brain cancer. Biochim. Biophys. Acta 1807, 577-594. doi: 10.1016/j.bbabio.2010.08.009
-
(2011)
Biochim. Biophys. Acta
, vol.1807
, pp. 577-594
-
-
Seyfried, T.N.1
Kiebish, M.A.2
Marsh, J.3
Shelton, L.M.4
Huysentruyt, L.C.5
Mukherjee, P.6
-
121
-
-
27744502691
-
Targeting energy metabolism in brain cancer: Review and hypothesis. Nutr
-
Seyfried, T. N., and Mukherjee, P. (2005). Targeting energy metabolism in brain cancer: review and hypothesis. Nutr. Metab. (Lond) 2:30. doi: 10.1186/1743-7075-2-30
-
(2005)
Metab. (Lond)
, vol.2
, pp. 30
-
-
Seyfried, T.N.1
Mukherjee, P.2
-
122
-
-
77956249320
-
Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse
-
Shelton, L. M., Huysentruyt, L. C., Mukherjee, P., and Seyfried, T. N. (2010). Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse. ASN Neuro 2:e00038. doi: 10.1042/AN20100002
-
(2010)
ASN Neuro
, vol.2
-
-
Shelton, L.M.1
Huysentruyt, L.C.2
Mukherjee, P.3
Seyfried, T.N.4
-
123
-
-
84872166360
-
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor
-
Shimazu, T., Hirschey, M. D., Newman, J., He, W., Shirakawa, K., Le Moan, N., et al. (2013). Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science 339, 211-214. doi: 10.1126/science.1227166
-
(2013)
Science
, vol.339
, pp. 211-214
-
-
Shimazu, T.1
Hirschey, M.D.2
Newman, J.3
He, W.4
Shirakawa, K.5
Le Moan, N.6
-
124
-
-
84923207192
-
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia
-
Shukla, S. K., Gebregiworgis, T., Purohit, V., Chaika, N. V., Gunda, V., Radhakrishnan, P., et al. (2014). Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia. Cancer Metab. 2:18. doi: 10.1186/2049-3002-2-18
-
(2014)
Cancer Metab
, vol.2
, pp. 18
-
-
Shukla, S.K.1
Gebregiworgis, T.2
Purohit, V.3
Chaika, N.V.4
Gunda, V.5
Radhakrishnan, P.6
-
125
-
-
84995974498
-
The ketone body β-hydroxybutyrate radiosensitizes glioblastoma multiforme stem cells
-
Silva-Nichols, H. B., Woolf, E. C., Deleyrolle, L. P., Reynolds, B. A., and Scheck, A. C. (2015). The ketone body β-hydroxybutyrate radiosensitizes glioblastoma multiforme stem cells. Neuro Oncol. 17:v35. doi: 10.1093/neuonc/nov204.77
-
(2015)
Neuro Oncol
, pp. 17
-
-
Silva-Nichols, H.B.1
Woolf, E.C.2
Deleyrolle, L.P.3
Reynolds, B.A.4
Scheck, A.C.5
-
126
-
-
84880231512
-
Selectively starving cancer cells through dietary manipulation: Methods and clinical implications
-
Simone, B. A., Champ, C. E., Rosenberg, A. L., Berger, A. C., Monti, D. A., Dicker, A. P., et al. (2013). Selectively starving cancer cells through dietary manipulation: methods and clinical implications. Future Oncol. 9, 959-976. doi: 10.2217/fon.13.31
-
(2013)
Future Oncol
, vol.9
, pp. 959-976
-
-
Simone, B.A.1
Champ, C.E.2
Rosenberg, A.L.3
Berger, A.C.4
Monti, D.A.5
Dicker, A.P.6
-
127
-
-
58149514084
-
Ketone bodies inhibit the viability of human neuroblastoma cells
-
Skinner, R., Trujillo, A., Ma, X., and Beierle, E. A. (2009). Ketone bodies inhibit the viability of human neuroblastoma cells. J. Pediatr. Surg. 44, 212-216. doi: 10.1016/j.jpedsurg.2008.10.042
-
(2009)
J. Pediatr. Surg
, vol.44
, pp. 212-216
-
-
Skinner, R.1
Trujillo, A.2
Ma, X.3
Beierle, E.A.4
-
128
-
-
77956465178
-
The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma
-
Stafford, P., Abdelwahab, M. G., Kim, D. Y., Preul, M. C., Rho, J. M., and Scheck, A. C. (2010). The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma. Nutr. Metab. (Lond) 7:74. doi: 10.1186/1743-7075-7-74
-
(2010)
Nutr. Metab. (Lond)
, vol.7
, pp. 74
-
-
Stafford, P.1
Abdelwahab, M.G.2
Kim, D.Y.3
Preul, M.C.4
Rho, J.M.5
Scheck, A.C.6
-
129
-
-
84943257841
-
MYC, metabolism and cancer
-
Stine, Z. E., Walton, Z. E., Altman, B. J., Hsieh, A. L., and Dang, C. V. (2015). MYC, metabolism and cancer. Cancer Discov. 5, 1024-1039. doi: 10.1158/2159-8290.CD-15-0507
-
(2015)
Cancer Discov
, vol.5
, pp. 1024-1039
-
-
Stine, Z.E.1
Walton, Z.E.2
Altman, B.J.3
Hsieh, A.L.4
Dang, C.V.5
-
130
-
-
0020674992
-
Loss of acetoacetate coenzyme A transferase activity in tumours of peripheral tissues
-
Tisdale, M. J., and Brennan, R. A. (1983). Loss of acetoacetate coenzyme A transferase activity in tumours of peripheral tissues. Br. J. Cancer 47, 293-297. doi: 10.1038/bjc.1983.38
-
(1983)
Br. J. Cancer
, vol.47
, pp. 293-297
-
-
Tisdale, M.J.1
Brennan, R.A.2
-
131
-
-
0023270392
-
Reduction of weight loss and tumour size in a cachexia model by a high fat diet
-
Tisdale, M. J., Brennan, R. A., and Fearon, K. C. (1987). Reduction of weight loss and tumour size in a cachexia model by a high fat diet. Br. J. Cancer 56, 39-43. doi: 10.1038/bjc.1987.149
-
(1987)
Br. J. Cancer
, vol.56
, pp. 39-43
-
-
Tisdale, M.J.1
Brennan, R.A.2
Fearon, K.C.3
-
132
-
-
79957516708
-
Response assessment in neuro-oncology (A report of the RANO group): Assessment of outcome in trials of diffuse low-grade gliomas
-
van den Bent, M. J., Wefel, J. S., Schiff, D., Taphoorn, M. J., Jaeckle, K., Junck, L., et al. (2011). Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas. Lancet Oncol. 12, 583-593. doi: 10.1016/s1470-2045(11)70057-2
-
(2011)
Lancet Oncol
, vol.12
, pp. 583-593
-
-
Van Den Bent, M.J.1
Wefel, J.S.2
Schiff, D.3
Taphoorn, M.J.4
Jaeckle, K.5
Junck, L.6
-
133
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden, M. G., Cantley, L. C., and Thompson, C. B. (2009). Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324, 1029-1033. doi: 10.1126/science.1160809
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
134
-
-
0141919698
-
Ketones: Metabolism’s ugly duckling
-
Vanitallie, T. B., and Nufert, T. H. (2003). Ketones: metabolism’s ugly duckling. Nutr. Rev. 61, 327-341. doi: 10.1301/nr.2003.oct.327-341
-
(2003)
Nutr. Rev
, vol.61
, pp. 327-341
-
-
Vanitallie, T.B.1
Nufert, T.H.2
-
135
-
-
1042299789
-
The therapeutic implications of ketone bodies: The effects of ketone bodies in pathological conditions: Ketosis, ketogenic diet, redox states, insulin resistance and mitochondrial metabolism. Prostaglandins Leukot
-
Veech, R. L. (2004). The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance and mitochondrial metabolism. Prostaglandins Leukot. Essent. Fatty Acids 70, 309-319. doi: 10.1016/j.plefa.2003.09.007
-
(2004)
Essent. Fatty Acids
, vol.70
, pp. 309-319
-
-
Veech, R.L.1
-
136
-
-
84904384275
-
Ketone ester effects on metabolism and transcription
-
Veech, R. L. (2014). Ketone ester effects on metabolism and transcription. J. Lipid Res. 55, 2004-2006. doi: 10.1194/jlr.r046292
-
(2014)
J. Lipid Res
, vol.55
, pp. 2004-2006
-
-
Veech, R.L.1
-
137
-
-
0034844219
-
Ketone bodies, potential therapeutic uses
-
Veech, R. L., Chance, B., Kashiwaya, Y., Lardy, H. A., and Cahill, G. F. Jr. (2001). Ketone bodies, potential therapeutic uses. IUBMB Life 51, 241-247. doi: 10.1080/152165401753311780
-
(2001)
IUBMB Life
, vol.51
, pp. 241-247
-
-
Veech, R.L.1
Chance, B.2
Kashiwaya, Y.3
Lardy, H.A.4
Cahill, G.F.5
-
138
-
-
84973598699
-
Anti-inflammatory and pro-resolving effects of N-3 PUFA in cancers: Structures and mechanisms
-
Wang, Q., Hu, M., Xu, H., and Yang, X. (2016). Anti-inflammatory and pro-resolving effects of N-3 PUFA in cancers: structures and mechanisms. Curr. Top. Med. Chem. 16, 888-894. doi: 10.2174/1568026615666150827101602
-
(2016)
Curr. Top. Med. Chem
, vol.16
, pp. 888-894
-
-
Wang, Q.1
Hu, M.2
Xu, H.3
Yang, X.4
-
139
-
-
84255167386
-
The powerful applications of polyunsaturated fatty acids in improving the therapeutic efficacy of anticancer drugs
-
Wang, J., Luo, T., Li, S., and Zhao, J. (2012). The powerful applications of polyunsaturated fatty acids in improving the therapeutic efficacy of anticancer drugs. Expert Opin. Drug Deliv. 9, 1-7. doi: 10.1517/17425247.2011.618183
-
(2012)
Expert Opin. Drug Deliv
, vol.9
, pp. 1-7
-
-
Wang, J.1
Luo, T.2
Li, S.3
Zhao, J.4
-
140
-
-
85006768050
-
The metabolism of tumors in the body
-
Warburg, O., Wind, F., and Negelein, E. (1927). The metabolism of tumors in the body. J. Gen. Physiol. 8, 519-530. doi: 10.1085/jgp.8.6.519
-
(1927)
J. Gen. Physiol
, vol.8
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
141
-
-
84858604270
-
Metabolic reprogramming: A cancer hallmark even warburg did not anticipate
-
Ward, P. S., and Thompson, C. B. (2012). Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 21, 297-308. doi: 10.1016/j.ccr.2012.02.014
-
(2012)
Cancer Cell
, vol.21
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
142
-
-
84876029468
-
Hypoxia induces a phase transition within a kinase signaling network in cancer cells
-
Wei, W., Shi, Q., Remacle, F., Qin, L., Shackelford, D. B., Shin, Y. S., et al. (2013). Hypoxia induces a phase transition within a kinase signaling network in cancer cells. Proc. Natl. Acad. Sci. U S A 110, E1352-E1360. doi: 10.1073/pnas.1303060110
-
(2013)
Proc. Natl. Acad. Sci. U S A
, vol.110
, pp. E1352-E1360
-
-
Wei, W.1
Shi, Q.2
Remacle, F.3
Qin, L.4
Shackelford, D.B.5
Shin, Y.S.6
-
143
-
-
84939123198
-
The ketogenic diet alters the hypoxic response and affects expression of proteins associated with angiogenesis, invasive potential and vascular permeability in a mouse glioma model
-
Woolf, E. C., Curley, K. L., Liu, Q., Turner, G. H., Charlton, J. A., Preul, M. C., et al. (2015). The ketogenic diet alters the hypoxic response and affects expression of proteins associated with angiogenesis, invasive potential and vascular permeability in a mouse glioma model. PLoS One 10:e0130357. doi: 10.1371/journal.pone.0130357
-
(2015)
Plos One
, vol.10
-
-
Woolf, E.C.1
Curley, K.L.2
Liu, Q.3
Turner, G.H.4
Charlton, J.A.5
Preul, M.C.6
-
144
-
-
0032992249
-
Cellular sensitization to cisplatin and carboplatin with decreased removal of platinum-DNA adduct by glucose-regulated stress
-
Yamada, M., Tomida, A., Yun, J., Cai, B., Yoshikawa, H., Taketani, Y., et al. (1999). Cellular sensitization to cisplatin and carboplatin with decreased removal of platinum-DNA adduct by glucose-regulated stress. Cancer Chemother. Pharmacol. 44, 59-64. doi: 10.1007/s002800050945
-
(1999)
Cancer Chemother. Pharmacol
, vol.44
, pp. 59-64
-
-
Yamada, M.1
Tomida, A.2
Yun, J.3
Cai, B.4
Yoshikawa, H.5
Taketani, Y.6
-
145
-
-
84866340817
-
Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications
-
Yang, L., Lin, C., Wang, L., Guo, H., and Wang, X. (2012). Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications. Exp. Cell Res. 318, 2417-2426. doi: 10.1016/j.yexcr.2012.07.017
-
(2012)
Exp. Cell Res
, vol.318
, pp. 2417-2426
-
-
Yang, L.1
Lin, C.2
Wang, L.3
Guo, H.4
Wang, X.5
-
146
-
-
70350217425
-
Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling
-
Yang, C., Sudderth, J., Dang, T., Bachoo, R. G., McDonald, J. G., and DeBerardinis, R. J. (2009). Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling. Cancer Res. 69, 7986-7993. doi: 10.1158/0008-5472.CAN-09-2266
-
(2009)
Cancer Res
, vol.69
, pp. 7986-7993
-
-
Yang, C.1
Sudderth, J.2
Dang, T.3
Bachoo, R.G.4
McDonald, J.G.5
Deberardinis, R.J.6
-
147
-
-
84924356420
-
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease
-
Youm, Y. H., Nguyen, K. Y., Grant, R. W., Goldberg, E. L., Bodogai, M., Kim, D., et al. (2015). The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Nat. Med. 21, 263-269. doi: 10.1038/nm.3804
-
(2015)
Nat. Med
, vol.21
, pp. 263-269
-
-
Youm, Y.H.1
Nguyen, K.Y.2
Grant, R.W.3
Goldberg, E.L.4
Bodogai, M.5
Kim, D.6
-
148
-
-
33847780073
-
The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer
-
Zhou, W., Mukherjee, P., Kiebish, M. A., Markis, W. T., Mantis, J. G., and Seyfried, T. N. (2007). The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer. Nutr. Metab. (Lond) 4:5. doi: 10.1186/1743-7075-4-5
-
(2007)
Nutr. Metab. (Lond)
, vol.4
, pp. 5
-
-
Zhou, W.1
Mukherjee, P.2
Kiebish, M.A.3
Markis, W.T.4
Mantis, J.G.5
Seyfried, T.N.6
-
149
-
-
77951028897
-
Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case report
-
Zuccoli, G., Marcello, N., Pisanello, A., Servadei, F., Vaccaro, S., Mukherjee, P., et al. (2010). Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: case report. Nutr. Metab. (Lond) 7:33. doi: 10.1186/1743-7075-7-33
-
(2010)
Nutr. Metab. (Lond)
, vol.7
, pp. 33
-
-
Zuccoli, G.1
Marcello, N.2
Pisanello, A.3
Servadei, F.4
Vaccaro, S.5
Mukherjee, P.6
-
150
-
-
84907202296
-
Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming
-
Zwaans, B. M., and Lombard, D. B. (2014). Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming. Dis. Model. Mech. 7, 1023-1032. doi: 10.1242/dmm.016287
-
(2014)
Dis. Model. Mech
, vol.7
, pp. 1023-1032
-
-
Zwaans, B.M.1
Lombard, D.B.2
|