The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

eLife

Volumn 2015, Issue 4, 2015, Pages

  Wei, Yongjie ^a,b   An, Zhenyi ^a   Zou, Zhongju ^a,b   Sumpter, Rhea ^a   Su, Minfei ^c   Zang, Xiao ^d   Sinha, Sangita ^c   Gaestel, Matthias ^e   Levine, Beth ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c NORTH DAKOTA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 5; BECLIN 1; ESTROGEN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN P62; STRESS ACTIVATED PROTEIN KINASE 1; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; CULTURE MEDIUM; MAP-KINASE-ACTIVATED KINASE 2; MAP-KINASE-ACTIVATED KINASE 3; MEMBRANE PROTEIN; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; FEMALE; GENE SILENCING; HEK293 CELL LINE; HELA CELL LINE; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; ISOTOPE LABELING; KWASHIORKOR; MAP KINASE ASSAY; MASS SPECTROMETRY; MCF 7 CELL LINE; MOUSE; NEUROBLASTOMA CELL LINE; NICK END LABELING; NONHUMAN; PLASMID; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STARVATION; TRANSIENT TRANSFECTION; TUMOR XENOGRAFT; U2OS CELL LINE; WESTERN BLOTTING; ANIMAL; CULTURE MEDIUM; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE, TUMOR; CULTURE MEDIA; GENES, TUMOR SUPPRESSOR; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 85003048223     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.05289     Document Type: Article

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