메뉴 건너뛰기




Volumn 55, Issue 1, 2016, Pages 115-135

Cognitive-enhancing effects of a polyphenols-rich extract from fruits without changes in neuropathology in an animal model of Alzheimer's disease

Author keywords

3xTg AD; age related cognitive decline; Alzheimer's disease; polyphenols

Indexed keywords

AMYLOID BETA PROTEIN; BLUEBERRY EXTRACT; DIHYDROXYPHENYL VALEROLACTONE; DRUG METABOLITE; POLYPHENOL DERIVATIVE; UNCLASSIFIED DRUG; VITIS VINIFERA EXTRACT; AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; BRAIN DERIVED NEUROTROPHIC FACTOR; MAPT PROTEIN, HUMAN; NOOTROPIC AGENT; PLANT EXTRACT; POLYPHENOL; PRESENILIN 1; PSEN1 PROTEIN, HUMAN; TAU PROTEIN;

EID: 84994663338     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-160281     Document Type: Article
Times cited : (52)

References (91)
  • 4
    • 3042857903 scopus 로고    scopus 로고
    • Alzheimer?s disease
    • Cummings JL (2004) Alzheimer?s disease. N Engl J Med 351, 56-67.
    • (2004) N Engl J Med , vol.351 , pp. 56-67
    • Cummings, J.L.1
  • 5
    • 38049018185 scopus 로고    scopus 로고
    • Biochemical characterization of Abeta and tau pathologies in mild cognitive impairment and Alzheimer?s disease
    • Tremblay C, Pilote M, Phivilay A, Emond V, Bennett DA, Calon F (2007) Biochemical characterization of Abeta and tau pathologies in mild cognitive impairment and Alzheimer?s disease. J Alzheimers Dis 12, 377-390.
    • (2007) J Alzheimers Dis , vol.12 , pp. 377-390
    • Tremblay, C.1    Pilote, M.2    Phivilay, A.3    Emond, V.4    Bennett, D.A.5    Calon, F.6
  • 8
    • 24644453571 scopus 로고    scopus 로고
    • The role of apoptotic pathways in Alzheimer?s disease neurodegeneration and cell death
    • LeBlanc AC (2005) The role of apoptotic pathways in Alzheimer?s disease neurodegeneration and cell death. Curr Alzheimer Res 2, 389-402.
    • (2005) Curr Alzheimer Res , vol.2 , pp. 389-402
    • LeBlanc, A.C.1
  • 9
    • 84903947419 scopus 로고    scopus 로고
    • Alzheimer?s disease drug-development pipeline: Few candidates, frequent failures
    • Cummings J, Morstorf T, Zhong K (2014) Alzheimer?s disease drug-development pipeline: Few candidates, frequent failures. Alzheimers Res Ther 6, 37.
    • (2014) Alzheimers Res Ther , vol.6 , pp. 37
    • Cummings, J.1    Morstorf, T.2    Zhong, K.3
  • 12
    • 84909971843 scopus 로고    scopus 로고
    • Lessons from a failed gammasecretase Alzheimer trial
    • De Strooper B (2014) Lessons from a failed gammasecretase Alzheimer trial. Cell 159, 721-726.
    • (2014) Cell , vol.159 , pp. 721-726
    • De Strooper, B.1
  • 13
    • 79959973322 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids in Alzheimer?s disease: Key questions and partial answers
    • Calon F (2011) Omega-3 polyunsaturated fatty acids in Alzheimer?s disease: Key questions and partial answers. Curr Alzheimer Res 8, 470-478.
    • (2011) Curr Alzheimer Res , vol.8 , pp. 470-478
    • Calon, F.1
  • 15
    • 84909633352 scopus 로고    scopus 로고
    • Nutrition and prevention of Alzheimer?s dementia
    • Swaminathan A, Jicha GA (2014) Nutrition and prevention of Alzheimer?s dementia. Front Aging Neurosci 6, 282.
    • (2014) Front Aging Neurosci , vol.6 , pp. 282
    • Swaminathan, A.1    Jicha, G.A.2
  • 16
    • 84896366752 scopus 로고    scopus 로고
    • Effect of flavonoids on learning, memory and neurocognitive performance: Relevance and potential implications for Alzheimer?s disease pathophysiology
    • Vauzour D (2014) Effect of flavonoids on learning, memory and neurocognitive performance: Relevance and potential implications for Alzheimer?s disease pathophysiology. J Sci Food Agric 94, 1042-1056.
    • (2014) J Sci Food Agric , vol.94 , pp. 1042-1056
    • Vauzour, D.1
  • 18
    • 70349106346 scopus 로고    scopus 로고
    • Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: Implications for treatment in Alzheimer?s disease
    • Ferruzzi MG, Lobo JK, Janle EM, Cooper B, Simon JE, Wu Q-L, Welch C, Ho L, Weaver C, Pasinetti GM (2009) Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: Implications for treatment in Alzheimer?s disease. J Alzheimers Dis 18, 113-124.
    • (2009) J Alzheimers Dis , vol.18 , pp. 113-124
    • Ferruzzi, M.G.1    Lobo, J.K.2    Janle, E.M.3    Cooper, B.4    Simon, J.E.5    Wu, Q.-L.6    Welch, C.7    Ho, L.8    Weaver, C.9    Pasinetti, G.M.10
  • 21
    • 84865458738 scopus 로고    scopus 로고
    • Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: The Cocoa, Cognition, and Aging (CoCoA) study
    • Desideri G, Kwik-Uribe C, Grassi D, Necozione S, Ghiadoni L, Mastroiacovo D, Raffaele A, Ferri L, Bocale R, Lechiara MC, Marini C, Ferri C (2012) Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: The Cocoa, Cognition, and Aging (CoCoA) study. Hypertension 60, 794-801.
    • (2012) Hypertension , vol.60 , pp. 794-801
    • Desideri, G.1    Kwik-Uribe, C.2    Grassi, D.3    Necozione, S.4    Ghiadoni, L.5    Mastroiacovo, D.6    Raffaele, A.7    Ferri, L.8    Bocale, R.9    Lechiara, M.C.10    Marini, C.11    Ferri, C.12
  • 22
    • 69549084549 scopus 로고    scopus 로고
    • Grape juice, berries, and walnuts affect brain aging and behavior
    • Joseph JA, Shukitt-Hale B, Willis LM (2009) Grape juice, berries, and walnuts affect brain aging and behavior. J Nutr 139, 1813S-1817S.
    • (2009) J Nutr , vol.139 , pp. 1813S-1817S
    • Joseph, J.A.1    Shukitt-Hale, B.2    Willis, L.M.3
  • 24
    • 84864452592 scopus 로고    scopus 로고
    • Dietary intakes of berries and flavonoids in relation to cognitive decline
    • Devore EE, Kang JH, Breteler MMB, Grodstein F (2012) Dietary intakes of berries and flavonoids in relation to cognitive decline. Ann Neurol 72, 135-143.
    • (2012) Ann Neurol , vol.72 , pp. 135-143
    • Devore, E.E.1    Kang, J.H.2    Breteler, M.M.B.3    Grodstein, F.4
  • 28
    • 84863714863 scopus 로고    scopus 로고
    • Dietary polyphenols as modulators of brain functions: Biological actions and molecular mechanisms underpinning their beneficial effects
    • Vauzour D (2012) Dietary polyphenols as modulators of brain functions: Biological actions and molecular mechanisms underpinning their beneficial effects. Oxid Med Cell Longev 2012, 914273.
    • (2012) Oxid Med Cell Longev , vol.2012 , pp. 914273
    • Vauzour, D.1
  • 29
    • 70450221663 scopus 로고    scopus 로고
    • Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects
    • Spencer JPE, Vauzour D, Rendeiro C (2009) Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects. Arch Biochem Biophys 492, 1-9.
    • (2009) Arch Biochem Biophys , vol.492 , pp. 1-9
    • Spencer, J.P.E.1    Vauzour, D.2    Rendeiro, C.3
  • 30
    • 71949107443 scopus 로고    scopus 로고
    • Flavonoids and brain health: Multiple effects underpinned by common mechanisms
    • Spencer J (2009) Flavonoids and brain health: Multiple effects underpinned by common mechanisms. Genes Nutr 4, 243-250.
    • (2009) Genes Nutr , vol.4 , pp. 243-250
    • Spencer, J.1
  • 31
    • 46749123053 scopus 로고    scopus 로고
    • Grape-derived polyphenolics prevent A-oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer?s disease
    • Wang J, Ho L, Zhao W, Ono K, Rosensweig C, Chen L, Humala N, Teplow DB, Pasinetti GM (2008) Grape-derived polyphenolics prevent A-oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer?s disease. J Neurosci 28, 6388-6392.
    • (2008) J Neurosci , vol.28 , pp. 6388-6392
    • Wang, J.1    Ho, L.2    Zhao, W.3    Ono, K.4    Rosensweig, C.5    Chen, L.6    Humala, N.7    Teplow, D.B.8    Pasinetti, G.M.9
  • 38
    • 84866636084 scopus 로고    scopus 로고
    • Sex-dependent alterations in social behaviour and cortical synaptic activity coincide at different ages in a model of Alzheimer?s disease
    • Bories C, Guitton MJ, Julien C, Tremblay C, Vandal M, Msaid M, De Koninck Y, Calon F (2012) Sex-dependent alterations in social behaviour and cortical synaptic activity coincide at different ages in a model of Alzheimer?s disease. PLoS One 7, e46111.
    • (2012) PLoS One , vol.7 , pp. e46111
    • Bories, C.1    Guitton, M.J.2    Julien, C.3    Tremblay, C.4    Vandal, M.5    Msaid, M.6    De Koninck, Y.7    Calon, F.8
  • 42
    • 48749102434 scopus 로고    scopus 로고
    • Metabolic syndrome and the role of dietary lifestyles in Alzheimer?s disease
    • Pasinetti GM, Eberstein JA (2008) Metabolic syndrome and the role of dietary lifestyles in Alzheimer?s disease. J Neurochem 106, 1503-1514.
    • (2008) J Neurochem , vol.106 , pp. 1503-1514
    • Pasinetti, G.M.1    Eberstein, J.A.2
  • 44
    • 84864411864 scopus 로고    scopus 로고
    • Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer?s disease expressing mutated APP, PS1, and Mapt (3xTg-AD)
    • Filali M, Lalonde R, Theriault P, Julien C, Calon F, Planel E (2012) Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer?s disease expressing mutated APP, PS1, and Mapt (3xTg-AD). Behav Brain Res 234, 334-342.
    • (2012) Behav Brain Res , vol.234 , pp. 334-342
    • Filali, M.1    Lalonde, R.2    Theriault, P.3    Julien, C.4    Calon, F.5    Planel, E.6
  • 45
    • 79952021693 scopus 로고    scopus 로고
    • DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice
    • Arsenault D, Julien C, Tremblay C, Calon F (2011) DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice. PLoS One 6, e17397.
    • (2011) PLoS One , vol.6 , pp. e17397
    • Arsenault, D.1    Julien, C.2    Tremblay, C.3    Calon, F.4
  • 46
    • 84897386461 scopus 로고    scopus 로고
    • IVIg protects the 3xTg-AD mouse model of Alzheimer?s disease from memory deficit and Abeta pathology
    • St-Amour I, Pare I, Tremblay C, Coulombe K, Bazin R, Calon F (2014) IVIg protects the 3xTg-AD mouse model of Alzheimer?s disease from memory deficit and Abeta pathology. J Neuroinflammation 11, 54.
    • (2014) J Neuroinflammation , vol.11 , pp. 54
    • St-Amour, I.1    Pare, I.2    Tremblay, C.3    Coulombe, K.4    Bazin, R.5    Calon, F.6
  • 47
    • 84864198258 scopus 로고    scopus 로고
    • Selective deletion of forebrain glycogen synthase kinase 3beta reveals a central role in serotonin-sensitive anxiety and social behaviour
    • Latapy C, Rioux V, Guitton MJ, Beaulieu JM (2012) Selective deletion of forebrain glycogen synthase kinase 3beta reveals a central role in serotonin-sensitive anxiety and social behaviour. Philos Trans R Soc Lond B Biol Sci 367, 2460-2474.
    • (2012) Philos Trans R Soc Lond B Biol Sci , vol.367 , pp. 2460-2474
    • Latapy, C.1    Rioux, V.2    Guitton, M.J.3    Beaulieu, J.M.4
  • 49
    • 84931266653 scopus 로고    scopus 로고
    • Object recognition test for studying cognitive impairments in animal models of Alzheimer?s disease
    • Bengoetxea X, Rodriguez-Perdigon M, Ramirez MJ (2015) Object recognition test for studying cognitive impairments in animal models of Alzheimer?s disease. Front Biosci (Schol Ed) 7, 10-29.
    • (2015) Front Biosci (Schol Ed) , vol.7 , pp. 10-29
    • Bengoetxea, X.1    Rodriguez-Perdigon, M.2    Ramirez, M.J.3
  • 50
    • 84455193348 scopus 로고    scopus 로고
    • Endogenous conversion of omega-6 into omega-3 fatty acids improves neuropathology in an animal model of Alzheimer?s disease
    • Lebbadi M, Julien C, Phivilay A, Tremblay C, Emond V, Kang JX, Calon F (2011) Endogenous conversion of omega-6 into omega-3 fatty acids improves neuropathology in an animal model of Alzheimer?s disease. J Alzheimers Dis 27, 853-869.
    • (2011) J Alzheimers Dis , vol.27 , pp. 853-869
    • Lebbadi, M.1    Julien, C.2    Phivilay, A.3    Tremblay, C.4    Emond, V.5    Kang, J.X.6    Calon, F.7
  • 51
    • 84860889573 scopus 로고    scopus 로고
    • The novel object recognition memory: Neurobiology, test procedure, and its modifications
    • Antunes M, Biala G (2012) The novel object recognition memory: Neurobiology, test procedure, and its modifications. Cogn Process 13, 93-110.
    • (2012) Cogn Process , vol.13 , pp. 93-110
    • Antunes, M.1    Biala, G.2
  • 52
    • 80052185880 scopus 로고    scopus 로고
    • Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease
    • Tremblay C, St-Amour I, Schneider J, Bennett D, Calon F (2011) Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease. J Neuropathol Exp Neurol 70, 788-798.
    • (2011) J Neuropathol Exp Neurol , vol.70 , pp. 788-798
    • Tremblay, C.1    St-Amour, I.2    Schneider, J.3    Bennett, D.4    Calon, F.5
  • 53
    • 84898001722 scopus 로고    scopus 로고
    • Modulation of strawberry/cranberry phenolic compounds glucuronidation by co-supplementation with onion: Characterization of phenolic metabolites in rat plasma using an optimized-SPE-UHPLC-MS/MS method
    • Dudonné S, Dubé P, Pilon G, Marette A, Jacques H, Weisnagel J, Desjardins Y (2014) Modulation of strawberry/cranberry phenolic compounds glucuronidation by co-supplementation with onion: Characterization of phenolic metabolites in rat plasma using an optimized-SPE-UHPLC-MS/MS method. J Agric Food Chem 62, 3244-3256.
    • (2014) J Agric Food Chem , vol.62 , pp. 3244-3256
    • Dudonné, S.1    Dubé, P.2    Pilon, G.3    Marette, A.4    Jacques, H.5    Weisnagel, J.6    Desjardins, Y.7
  • 55
    • 0038291981 scopus 로고    scopus 로고
    • Conformational changes and truncation of tau protein during tangle evolution in Alzheimer?s disease
    • Garcia-Sierra F, Ghoshal N, Quinn B, Berry RW, Binder LI (2003) Conformational changes and truncation of tau protein during tangle evolution in Alzheimer?s disease. J Alzheimers Dis 5, 65-77.
    • (2003) J Alzheimers Dis , vol.5 , pp. 65-77
    • Garcia-Sierra, F.1    Ghoshal, N.2    Quinn, B.3    Berry, R.W.4    Binder, L.I.5
  • 56
    • 34347215149 scopus 로고    scopus 로고
    • Object recognition in rats and mice: A one-Trial non-matching-To-sample learning task to study ?recognition memory?
    • Bevins RA, Besheer J (2006) Object recognition in rats and mice: A one-Trial non-matching-To-sample learning task to study ?recognition memory?. Nat Protoc 1, 1306-1311.
    • (2006) Nat Protoc , vol.1 , pp. 1306-1311
    • Bevins, R.A.1    Besheer, J.2
  • 57
    • 77957933189 scopus 로고    scopus 로고
    • Quercetin activates AMP-Activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity
    • Lu J, Wu D-M, Zheng Y-L, Hu B, Zhang Z-F, Shan Q, Zheng Z-H, Liu C-M, Wang Y-J (2010) Quercetin activates AMP-Activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity. J Pathol 222, 199-212.
    • (2010) J Pathol , vol.222 , pp. 199-212
    • Lu, J.1    Wu, D.-M.2    Zheng, Y.-L.3    Hu, B.4    Zhang, Z.-F.5    Shan, Q.6    Zheng, Z.-H.7    Liu, C.-M.8    Wang, Y.-J.9
  • 60
    • 84872746217 scopus 로고    scopus 로고
    • Long-Term dietary extra-virgin olive oil rich in polyphenols reverses age-related dysfunctions in motor coordination and contextual memory in mice: Role of oxidative stress
    • Pitozzi V, Jacomelli M, Catelan D, Servili M, Taticchi A, Biggeri A, Dolara P, Giovannelli L (2012) Long-Term dietary extra-virgin olive oil rich in polyphenols reverses age-related dysfunctions in motor coordination and contextual memory in mice: Role of oxidative stress. Rejuvenation Res 15, 601-612.
    • (2012) Rejuvenation Res , vol.15 , pp. 601-612
    • Pitozzi, V.1    Jacomelli, M.2    Catelan, D.3    Servili, M.4    Taticchi, A.5    Biggeri, A.6    Dolara, P.7    Giovannelli, L.8
  • 62
    • 46749094132 scopus 로고    scopus 로고
    • Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels
    • Williams CM, El Mohsen MA, Vauzour D, Rendeiro C, Butler LT, Ellis JA, Whiteman M, Spencer JPE (2008) Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels. Free Radic Biol Med 45, 295-305.
    • (2008) Free Radic Biol Med , vol.45 , pp. 295-305
    • Williams, C.M.1    El Mohsen, M.A.2    Vauzour, D.3    Rendeiro, C.4    Butler, L.T.5    Ellis, J.A.6    Whiteman, M.7    Spencer, J.P.E.8
  • 70
    • 77953704732 scopus 로고    scopus 로고
    • Role of drebrin A in dendritic spine plasticity and synaptic function: Implications in neurological disorders
    • Ivanov A, Esclapez M, Ferhat L (2009) Role of drebrin A in dendritic spine plasticity and synaptic function: Implications in neurological disorders. Commun Integr Biol 2, 268-270.
    • (2009) Commun Integr Biol , vol.2 , pp. 268-270
    • Ivanov, A.1    Esclapez, M.2    Ferhat, L.3
  • 71
    • 84892715064 scopus 로고    scopus 로고
    • Resveratrol increases cerebral glycogen synthase kinase phosphorylation as well as protein levels of drebrin and transthyretin in mice: An exploratory study
    • Varamini B, Sikalidis AK, Bradford KL (2014) Resveratrol increases cerebral glycogen synthase kinase phosphorylation as well as protein levels of drebrin and transthyretin in mice: An exploratory study. Int J Food Sci Nutr 65, 89-96.
    • (2014) Int J Food Sci Nutr , vol.65 , pp. 89-96
    • Varamini, B.1    Sikalidis, A.K.2    Bradford, K.L.3
  • 73
    • 84911007828 scopus 로고    scopus 로고
    • Neural stem cell transplants improve cognitive function without altering amyloid pathology in an APP/PS1 double transgenic model of Alzheimer?s disease
    • Zhang W, Wang P-J, Sha H-Y, Ni J, Li M-H, Gu G-J (2014) Neural stem cell transplants improve cognitive function without altering amyloid pathology in an APP/PS1 double transgenic model of Alzheimer?s disease. Mol Neurobiol 50, 423-437.
    • (2014) Mol Neurobiol , vol.50 , pp. 423-437
    • Zhang, W.1    Wang, P.-J.2    Sha, H.-Y.3    Ni, J.4    Li, M.-H.5    Gu, G.-J.6
  • 77
    • 84906561770 scopus 로고    scopus 로고
    • Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer?s disease
    • Kazim SF, Blanchard J, Dai C-L, Tung Y-C, LaFerla FM, Iqbal I-G, Iqbal K (2014) Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer?s disease. Neurobiol Dis 71, 110-130.
    • (2014) Neurobiol Dis , vol.71 , pp. 110-130
    • Kazim, S.F.1    Blanchard, J.2    Dai, C.-L.3    Tung, Y.-C.4    LaFerla, F.M.5    Iqbal, I.-G.6    Iqbal, K.7
  • 79
    • 0036742611 scopus 로고    scopus 로고
    • From acquisition to consolidation: On the role of brain-derived neurotrophic factor signaling in hippocampaldependent learning
    • Tyler WJ, Alonso M, Bramham CR, Pozzo-Miller LD (2002) From acquisition to consolidation: On the role of brain-derived neurotrophic factor signaling in hippocampaldependent learning. Learn Mem 9, 224-237.
    • (2002) Learn Mem , vol.9 , pp. 224-237
    • Tyler, W.J.1    Alonso, M.2    Bramham, C.R.3    Pozzo-Miller, L.D.4
  • 82
    • 84864533900 scopus 로고    scopus 로고
    • Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Abeta or tau pathology
    • Castello NA, Green KN, LaFerla FM (2012) Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Abeta or tau pathology. PLoS One 7, e39566.
    • (2012) PLoS One , vol.7 , pp. e39566
    • Castello, N.A.1    Green, K.N.2    LaFerla, F.M.3
  • 83
    • 84893723488 scopus 로고    scopus 로고
    • Neuropep-1 ameliorates learning and memory deficits in an Alzheimer?s disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques
    • Shin M-K, Kim H-G, Baek S-H, Jung W-R, Park D-I, Park J-S, Jo D-G, Kim K-L (2014) Neuropep-1 ameliorates learning and memory deficits in an Alzheimer?s disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques. Neurobiol Aging 35, 990-1001.
    • (2014) Neurobiol Aging , vol.35 , pp. 990-1001
    • Shin, M.-K.1    Kim, H.-G.2    Baek, S.-H.3    Jung, W.-R.4    Park, D.-I.5    Park, J.-S.6    Jo, D.-G.7    Kim, K.-L.8
  • 85
    • 0037163110 scopus 로고    scopus 로고
    • Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action
    • Levites Y, Amit T, Youdim MBH, Mandel S (2002) Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action. J Biol Chem 277, 30574-30580.
    • (2002) J Biol Chem , vol.277 , pp. 30574-30580
    • Levites, Y.1    Amit, T.2    Youdim, M.B.H.3    Mandel, S.4
  • 86
    • 41549100684 scopus 로고    scopus 로고
    • Chlorogenic acid and its metabolite m-coumaric acid evoke neurite outgrowth in hippocampal neuronal cells
    • Ito H, Sun X-L, Watanabe M, Okamoto M, Hatano T (2008) Chlorogenic acid and its metabolite m-coumaric acid evoke neurite outgrowth in hippocampal neuronal cells. Biosci Biotechnol Biochem 72, 885-888.
    • (2008) Biosci Biotechnol Biochem , vol.72 , pp. 885-888
    • Ito, H.1    Sun, X.-L.2    Watanabe, M.3    Okamoto, M.4    Hatano, T.5
  • 87
    • 20144371838 scopus 로고    scopus 로고
    • Green tea polyphenol (-)-epigallocatechin-3-gallate induces neurorescue of long-Term serum-deprived PC12 cells and promotes neurite outgrowth
    • Reznichenko L, Amit T, Youdim MBH, Mandel S (2005) Green tea polyphenol (-)-epigallocatechin-3-gallate induces neurorescue of long-Term serum-deprived PC12 cells and promotes neurite outgrowth. J Neurochem 93, 1157-1167.
    • (2005) J Neurochem , vol.93 , pp. 1157-1167
    • Reznichenko, L.1    Amit, T.2    Youdim, M.B.H.3    Mandel, S.4
  • 88
    • 33645519220 scopus 로고    scopus 로고
    • Long-Term administration of green tea catechins improves spatial cognition learning ability in rats
    • Haque AM, Hashimoto M, Katakura M, Tanabe Y, Hara Y, Shido O (2006) Long-Term administration of green tea catechins improves spatial cognition learning ability in rats. J Nutr 136, 1043-1047.
    • (2006) J Nutr , vol.136 , pp. 1043-1047
    • Haque, A.M.1    Hashimoto, M.2    Katakura, M.3    Tanabe, Y.4    Hara, Y.5    Shido, O.6
  • 90
    • 33750832268 scopus 로고    scopus 로고
    • Flavonoid fisetin promotes ERK-dependent long-Term potentiation and enhances memory
    • Maher P, Akaishi T, Abe K (2006) Flavonoid fisetin promotes ERK-dependent long-Term potentiation and enhances memory. Proc Natl Acad Sci U S A 103, 16568-16573.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 16568-16573
    • Maher, P.1    Akaishi, T.2    Abe, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.