BDNF overexpression increases dendrite complexity in hippocampal dentate gyrus

Neuroscience

Volumn 114, Issue 3, 2002, Pages 795-805

  Tolwani, R J ^a   Buckmaster, P S ^a   Varma, S ^a   Cosgaya, J M ^a   Wu, Y ^a   Suri, C ^b   Shooter, E M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

Brain derived neurotrophic factor; Dendrite structure; Dentate gyrus; Granule cells; Plasticity; TrkB receptor

Indexed keywords

BETA ACTIN; BRAIN DERIVED NEUROTROPHIC FACTOR; ISOPROTEIN; TYROSINE KINASE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL LEVEL; CONTROLLED STUDY; DENDRITE; DENTATE GYRUS; GENE OVEREXPRESSION; GRANULE CELL; HIPPOCAMPUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DENDRITES; DENTATE GYRUS; HIPPOCAMPUS; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; NEURONAL PLASTICITY;

EID: 0037063706     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00301-9     Document Type: Article

References (49)

1. Allendoerfer K.L., Cabelli R.J., Escandon E., Kaplan D.R., Nikolics K., Shatz C.J. Regulation of neurotrophin receptors during the maturation of the mammalian visual system. J. Neurosci. 14:1994;1795-1811.
2. Atwal J.K., Massie B., Miller F.D., Kaplan D.R. The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron. 27:2000;265-277.
3. Barbacid M. The Trk family of neurotrophin receptors. J. Neurobiol. 25:1994;1386-1403.
4. Bartlett S.E., Reynolds A.J., Weible M., Heydon K., Hendry I.A. In sympathetic but not sensory neurones, phosphoinositide-3 kinase is important for NGF-dependent survival and the retrograde transport of 125I-betaNGF. Brain Res. 761:1997;257-262.
5. Baxter G.T., Radeke M.J., Kuo R.C., Makrides V., Hinkle B., Hoang R., Medina-Selby A., Coit D., Valenzuela P., Feinstein S.C. Signal transduction mediated by the truncated trkB receptor isoforms, trkB.T1 and trkB.T2. J. Neurosci. 17:1997;2683-2690.
6. Biffo S., Offenhauser N., Carter B.D., Barde Y.A. Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development. Development. 121:1995;2461-2470.
7. Bishop A.L., Hall A. Rho GTPases and their effector proteins. Biochem. J. 348:(Pt. 2):2000;241-255.
8. Blochl A., Thoenen H. Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium-dependent regulated pathway. Eur. J. Neurosci. 7:1995;1220-1228.
9. Buckmaster P.S., Amaral D.G. Intracellular recording and labeling of mossy cells and proximal CA3 pyramidal cells in macaque monkeys. J. Comp. Neurol. 430:2001;264-281.
10. Cabelli R.J., Hohn A., Shatz C.J. Inhibition of ocular dominance column formation by infusion of NT-4/5 or BDNF. Science. 267:1995;1662-1666.
11. Claiborne B.J., Amaral D.G., Cowan W.M. Quantitative, three-dimensional analysis of granule cell dendrites in the rat dentate gyrus. J. Comp. Neurol. 302:1990;206-219.
12. Cohen-Cory S. BDNF modulates, but does not mediate, activity-dependent branching and remodeling of optic axon arbors in vivo. J. Neurosci. 19:1999;9996-10003.
13. Cohen-Cory S., Fraser S.E. BDNF in the development of the visual system of Xenopus. Neuron. 12:1994;747-761.
14. Croll S.D., Suri C., Compton D.L., Simmons M.V., Yancopoulos G.D., Lindsay R.M., Wiegand S.J., Rudge J.S., Scharfman H.E. Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience. 93:1999;1491-1506.
15. Crowder R.J., Freeman R.S. Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons. J. Neurosci. 18:1998;2933-2943.
16. DePrimo S.E., Stambrook P.J., Stringer J.R. Human placental alkaline phosphatase as a histochemical marker of gene expression in transgenic mice. Transgenic. Res. 5:1996;459-466.
17. Eide F.F., Vining E.R., Eide B.L., Zang K., Wang X.Y., Reichardt L.F. Naturally occurring truncated trkB receptors have dominant inhibitory effects on brain-derived neurotrophic factor signaling. J. Neurosci. 16:1996;3123-3129.
18. Escandon E., Soppet D., Rosenthal A., Mendoza-Ramirez J.L., Szonyi E., Burton L.E., Henderson C.E., Parada L.F., Nikolics K. Regulation of neurotrophin receptor expression during embryonic and postnatal development. J. Neurosci. 14:1994;2054-2068.
19. Frank L., Ventimiglia R., Anderson K., Lindsay R.M., Rudge J.S. BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons. Eur. J. Neurosci. 8:1996;1220-1230.
20. Fryer R.H., Kaplan D.R., Feinstein S.C., Radeke M.J., Grayson D.R., Kromer L.F. Developmental and mature expression of full-length and truncated TrkB receptors in the rat forebrain. J. Comp. Neurol. 374:1996;21-40.
21. Fryer R.H., Kaplan D.R., Kromer L.F. Truncated trkB receptors on nonneuronal cells inhibit BDNF-induced neurite outgrowth in vitro. Exp. Neurol. 148:1997;616-627.
22. Horch H.W., Kruttgen A., Portbury S.D., Katz L.C. Destabilization of cortical dendrites and spines by BDNF. Neuron. 23:1999;353-364.
23. Huang E.J., Reichardt L.F. Neurotrophins: roles in neuronal development and function. Annu. Rev. Neurosci. 24:2001;677-736.
24. Kang H., Schuman E.M. Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science. 267:1995;1658-1662.
25. Kang H.J., Schuman E.M. Neurotrophin-induced modulation of synaptic transmission in the adult hippocampus. J. Physiol. Paris. 89:1995;11-22.
26. Kaplan D.R., Miller F.D. Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10:2000;381-391.
27. Katz L.C., Shatz C.J. Synaptic activity and the construction of cortical circuits. Science. 274:1996;1133-1138.
28. Kempermann G., Kuhn H.G., Gage F.H. Genetic influence on neurogenesis in the dentate gyrus of adult mice. Proc. Natl. Acad. Sci. USA. 94:1997;10409-10414.
29. Knusel B., Gao H., Okazaki T., Yoshida T., Mori N., Hefti F., Kaplan D.R. Ligand-induced down-regulation of Trk messenger RNA, protein and tyrosine phosphorylation in rat cortical neurons. Neuroscience. 78:1997;851-862.
30. Korte M., Carroll P., Wolf E., Brem G., Thoenen H., Bonhoeffer T. Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc. Natl. Acad. Sci. USA. 92:1995;8856-8860.
31. Kuruvilla R., Ye H., Ginty D.D. Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons. Neuron. 27:2000;499-512.
32. Lewin G.R., Barde Y.A. Physiology of the neurotrophins. Annu. Rev. Neurosci. 19:1996;289-317.
33. Liu B.P., Burridge K. Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins. Mol. Cell. Biol. 20:2000;7160-7169.
34. Lom B., Cohen-Cory S. Brain-derived neurotrophic factor differentially regulates retinal ganglion cell dendritic and axonal arborization in vivo. J. Neurosci. 19:1999;9928-9938.
35. Maisonpierre P.C., Belluscio L., Friedman B., Alderson R.F., Wiegand S.J., Furth M.E., Lindsay R.M., Yancopoulos G.D. NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression. Neuron. 5:1990;501-509.
36. McAllister A.K., Katz L.C., Lo D.C. Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. Neuron. 18:1997;767-778.
37. McAllister A.K., Katz L.C., Lo D.C. Neurotrophins and synaptic plasticity. Annu. Rev. Neurosci. 22:1999;295-318.
38. McAllister A.K., Lo D.C., Katz L.C. Neurotrophins regulate dendritic growth in developing visual cortex. Neuron. 15:1995;791-803.
39. Merlio J.P., Ernfors P., Kokaia Z., Middlemas D.S., Bengzon J., Kokaia M., Smith M.L., Siesjo B.K., Hunter T., Lindvall O. Increased production of the TrkB protein tyrosine kinase receptor after brain insults. Neuron. 10:1993;151-164.
40. Moller J.C., Kruttgen A., Heymach J.V.J., Ghori N., Shooter E.M. Subcellular localization of epitope-tagged neurotrophins in neuroendocrine cells. J. Neurosci. Res. 51:1998;463-472.
41. Ninkina N., Adu J., Fischer A., Pinon L.G., Buchman V.L., Davies A.M. Expression and function of TrkB variants in developing sensory neurons. EMBO J. 15:1996;6385-6393.
42. Qiao X., Sury C., Knusel B., Noebels J.L. Absence of hippocampal mossy fiber sprouting in transgenic overexpressing brain-derived neurotrophic factor. J. Neurosci. Res. 64:2001;268-276.
43. Rihn L.L., Claiborne B.J. Dendritic growth and regression in rat dentate granule cells during late postnatal development. Brain Res. Dev. Brain Res. 54:1990;115-124.
44. Schlessinger A.R., Cowan W.M., Gottlieb D.I. An autoradiographic study of the time of origin and the pattern of granule cell migration in the dentate gyrus of the rat. J. Comp. Neurol. 159:1975;149-175.
45. Sholl D.A. Dendrite organization in the neurons of the visual cortices of the cat. J. Anat. 87:1953;387-406.
46. Sommerfeld M.T., Schweigreiter R., Barde Y.A., Hoppe E. Down-regulation of the neurotrophin receptor TrkB following ligand binding. Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB. J. Biol. Chem. 275:2000;8982-8990.
47. Xu B., Gottschalk W., Chow A., Wilson R.I., Schnell E., Zang K., Wang D., Nicoll R.A., Lu B., Reichardt L.F. The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB. J. Neurosci. 20:2000;6888-6897.
48. Xu B., Zang K., Ruff N.L., Zhang Y.A., McConnell S.K., Stryker M.P., Reichardt L.F. Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB. Neuron. 26:2000;233-245.
49. Yacoubian T.A., Lo D.C. Truncated and full-length TrkB receptors regulate distinct modes of dendritic growth. Nat. Neurosci. 3:2000;342-349.