-
1
-
-
67749133873
-
TDP-43 is intrinsically aggregationprone and ALS-linked mutations accelerate aggregation and increase toxicity
-
Johnson BS, Snead D, Lee JJ, et al. TDP-43 is intrinsically aggregationprone and ALS-linked mutations accelerate aggregation and increase toxicity. J Biol Chem 2009;284:20329-39
-
(2009)
J Biol Chem
, vol.284
, pp. 20329-39
-
-
Johnson, B.S.1
Snead, D.2
Lee, J.J.3
-
2
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
DOI 10.1126/science.1154584
-
Sreedharan J, Blair IP, Tripathi VB, et al. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science 2008;319:1668-72 (Pubitemid 351432505)
-
(2008)
Science
, vol.319
, Issue.5870
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
Hu, X.4
Vance, C.5
Rogelj, B.6
Ackerley, S.7
Durnall, J.C.8
Williams, K.L.9
Buratti, E.10
Baralle, F.11
De Belleroche, J.12
Mitchell, J.D.13
Leigh, P.N.14
Al-Chalabi, A.15
Miller, C.C.16
Nicholson, G.17
Shaw, C.E.18
-
3
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
DOI 10.1126/science.1134108
-
Neumann M, Sampathu DM, Kwong LK, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006;314:130-33 (Pubitemid 44547757)
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.-Y.19
-
4
-
-
34249946466
-
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
-
DOI 10.1002/ana.21147
-
Mackenzie IRA, Bigio EH, Ince PG, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann Neurol 2007;61:427-34 (Pubitemid 46878770)
-
(2007)
Annals of Neurology
, vol.61
, Issue.5
, pp. 427-434
-
-
Mackenzie, I.R.A.1
Bigio, E.H.2
Ince, P.G.3
Geser, F.4
Neumann, M.5
Cairns, N.J.6
Kwong, L.K.7
Forman, M.S.8
Ravits, J.9
Stewart, H.10
Eisen, A.11
McClusky, L.12
Kretzschmar, H.A.13
Monoranu, C.M.14
Highley, J.R.15
Kirby, J.16
Siddique, T.17
Shaw, P.J.18
Lee, V.M.-Y.19
Trojanowski, J.Q.20
more..
-
5
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
DOI 10.1016/j.bbrc.2006.10.093, PII S0006291X06023187
-
Arai T, Hasegawa M, Akiyama H, et al. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 2006;351:602-11 (Pubitemid 44708852)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.351
, Issue.3
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
6
-
-
77649187519
-
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: An update
-
Mackenzie IR, Neumann M, Bigio EH, et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: An update. Acta Neuropathol 2010;119:1-4
-
(2010)
Acta Neuropathol
, vol.119
, pp. 1-4
-
-
MacKenzie, I.R.1
Neumann, M.2
Bigio, E.H.3
-
7
-
-
77649252528
-
Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis
-
Pesiridis GS, Lee VMY, Trojanowski JQ. Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis. Hum Mol Genet 2009;18:R156-62
-
(2009)
Hum Mol Genet
, vol.18
-
-
Pesiridis, G.S.1
Vmy, L.2
Trojanowski, J.Q.3
-
9
-
-
59649086176
-
Molecular neuropathology of TDP-43 proteinopathies
-
Neumann M. Molecular neuropathology of TDP-43 proteinopathies. Int J Mol Sci 2009;10:232-46
-
(2009)
Int J Mol Sci
, vol.10
, pp. 232-246
-
-
Neumann, M.1
-
10
-
-
60549117972
-
Clinical and pathological continuum of multisystem TDP-43 proteinopathies
-
Geser F, Martinez-Lage M, Robinson J, et al. Clinical and pathological continuum of multisystem TDP-43 proteinopathies. Arch Neurol 2009; 66:180-89
-
(2009)
Arch Neurol
, vol.66
, pp. 180-189
-
-
Geser, F.1
Martinez-Lage, M.2
Robinson, J.3
-
11
-
-
69549114542
-
The molecular links between TDP-43 dysfunction and neurodegeneration
-
Buratti E, Baralle FE. The molecular links between TDP-43 dysfunction and neurodegeneration. Adv Genet 2009;66:1-34
-
(2009)
Adv Genet
, vol.66
, pp. 1-34
-
-
Buratti, E.1
Baralle, F.E.2
-
12
-
-
68349125007
-
Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: The TDP-43 diseases
-
Geser F, Martinez-Lage M, Kwong LK, et al. Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: The TDP-43 diseases. J Neurol 2009;256:1205-14
-
(2009)
J Neurol
, vol.256
, pp. 1205-1214
-
-
Geser, F.1
Martinez-Lage, M.2
Kwong, L.K.3
-
13
-
-
77951700391
-
Nuclear factor TDP-43 can affect selected microRNA levels
-
Buratti E, De Conti L, Stuani C, et al. Nuclear factor TDP-43 can affect selected microRNA levels. FEBS J 2010;277:2268-81
-
(2010)
FEBS J
, vol.277
, pp. 2268-2281
-
-
Buratti, E.1
De Conti, L.2
Stuani, C.3
-
14
-
-
67649797399
-
Expression of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 poteinopathies
-
Igaz LM, Kwong LK, Chen-Plotkin A, et al. Expression of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 poteinopathies. J Biol Chem 2009;284:8516-24
-
(2009)
J Biol Chem
, vol.284
, pp. 8516-8524
-
-
Igaz, L.M.1
Kwong, L.K.2
Chen-Plotkin, A.3
-
15
-
-
60849093466
-
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
-
Rothstein JD. Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann Neurol 2009;65(Suppl 1):S3-9
-
(2009)
Ann Neurol
, vol.65
, Issue.SUPPL.1
-
-
Rothstein, J.D.1
-
16
-
-
34547663747
-
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions
-
DOI 10.2353/ajpath.2007.070182
-
Cairns NJ, Neumann M, Bigio EH, et al. TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am J Pathol 2007;171:227-40 (Pubitemid 47342406)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.1
, pp. 227-240
-
-
Cairns, N.J.1
Neumann, M.2
Bigio, E.H.3
Holm, I.E.4
Troost, D.5
Hatanpaa, K.J.6
Foong, C.7
White III, C.L.8
Schneider, J.A.9
Kretzschmar, H.A.10
Carter, D.11
Taylor-Reinwald, L.12
Paulsmeyer, K.13
Strider, J.14
Gitcho, M.15
Goate, A.M.16
Morris, J.C.17
Mishra, M.18
Kwong, L.K.19
Stieber, A.20
Xu, Y.21
Forman, M.S.22
Trojanowski, J.Q.23
Lee, V.M.-Y.24
Mackenzie, I.R.A.25
more..
-
17
-
-
66149114101
-
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
-
Zhang YJ, Xu YF, Cook C, et al. Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc Natl Acad Sci USA 2009;106: 7607-12
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7607-7612
-
-
Zhang, Y.J.1
Xu, Y.F.2
Cook, C.3
-
18
-
-
47949086625
-
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Hasegawa M, Arai T, Nonaka T, et al. Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann Neurol 2008;64:60-70
-
(2008)
Ann Neurol
, vol.64
, pp. 60-70
-
-
Hasegawa, M.1
Arai, T.2
Nonaka, T.3
-
19
-
-
47949084000
-
Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer disease
-
Hu WT, Josephs KA, Knopman DS, et al. Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer disease. Acta Neuropathol 2008;116:215-20
-
(2008)
Acta Neuropathol
, vol.116
, pp. 215-220
-
-
Hu, W.T.1
Josephs, K.A.2
Knopman, D.S.3
-
20
-
-
70349308579
-
Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: Their relation to AD common pathology
-
Kadokura A, Yamazaki T, Lemere CA, et al. Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: Their relation to AD common pathology. Neuropathology 2009;29:566-73
-
(2009)
Neuropathology
, vol.29
, pp. 566-573
-
-
Kadokura, A.1
Yamazaki, T.2
Lemere, C.A.3
-
21
-
-
44649137415
-
Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies
-
DOI 10.1097/NEN.0b013e31817713b5, PII 0000507220080600000004
-
Uryu K, Nakashima-Yasuda H, Forman MS, et al. Concomitant TARDNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies. J Neuropathol Exp Neurol 2008;67:555-64 (Pubitemid 351787082)
-
(2008)
Journal of Neuropathology and Experimental Neurology
, vol.67
, Issue.6
, pp. 555-564
-
-
Uryu, K.1
Nakashima-Yasuda, H.2
Forman, M.S.3
Kwong, L.K.4
Clark, C.M.5
Grossman, M.6
Miller, B.L.7
Kretzschmar, H.A.8
Lee, V.M.-Y.9
Trojanowski, J.Q.10
Neumann, M.11
-
22
-
-
59249097160
-
Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies
-
Arai T, Mackenzie IRA, Hasegawa M, et al. Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies. Acta Neuropathol 2009;117:125-36
-
(2009)
Acta Neuropathol
, vol.117
, pp. 125-136
-
-
Arai, T.1
Ira, M.2
Hasegawa, M.3
-
23
-
-
34249949338
-
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
-
DOI 10.1002/ana.21154
-
Amador-Ortiz C, Lin WL, Ahmed Z, et al. TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann Neurol 2007;61: 435-45 (Pubitemid 46878771)
-
(2007)
Annals of Neurology
, vol.61
, Issue.5
, pp. 435-445
-
-
Amador-Ortiz, C.1
Lin, W.-L.2
Ahmed, Z.3
Personett, D.4
Davies, P.5
Duara, R.6
Graff-Radford, N.R.7
Hutton, M.L.8
Dickson, D.W.9
-
24
-
-
36348972414
-
Concurrence of TDP-43, tau and α-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies
-
DOI 10.1016/j.brainres.2007.09.048, PII S000689930702224X
-
Higashi S, Iseki E, Yamamoto R, et al. Concurrence of TDP-43, tau and [alpha]-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies. Brain Res 2007;1184:284-94 (Pubitemid 350160566)
-
(2007)
Brain Research
, vol.1184
, Issue.1
, pp. 284-294
-
-
Higashi, S.1
Iseki, E.2
Yamamoto, R.3
Minegishi, M.4
Hino, H.5
Fujisawa, K.6
Togo, T.7
Katsuse, O.8
Uchikado, H.9
Furukawa, Y.10
Kosaka, K.11
Arai, H.12
-
25
-
-
43249094487
-
Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype
-
Josephs KA, Whitwell JL, Knopman DS, et al. Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype. Neurology 2008;70:1850
-
(2008)
Neurology
, vol.70
, pp. 1850
-
-
Josephs, K.A.1
Whitwell, J.L.2
Knopman, D.S.3
-
26
-
-
79956214776
-
TAR-DNA binding protein-43 and alterations in the hippocampus
-
Rauramaa T, Pikkarainen M, Englund E, et al. TAR-DNA binding protein-43 and alterations in the hippocampus. J Neural Transm 2011; 118:683-89
-
(2011)
J Neural Transm
, vol.118
, pp. 683-689
-
-
Rauramaa, T.1
Pikkarainen, M.2
Englund, E.3
-
27
-
-
77954149731
-
Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease
-
King A, Sweeney F, Bodi I, et al. Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease. Neuropathology 2010;30:408-19
-
(2010)
Neuropathology
, vol.30
, pp. 408-419
-
-
King, A.1
Sweeney, F.2
Bodi, I.3
-
28
-
-
77953870289
-
TDP-43 pathology in primary progressive aphasia and frontotemporal dementia with pathologic Alzheimer disease
-
Bigio EH, Mishra M, Hatanpaa KJ, et al. TDP-43 pathology in primary progressive aphasia and frontotemporal dementia with pathologic Alzheimer disease. Acta Neuropathol 2010;120:43-54
-
(2010)
Acta Neuropathol
, vol.120
, pp. 43-54
-
-
Bigio, E.H.1
Mishra, M.2
Hatanpaa, K.J.3
-
29
-
-
49349104833
-
Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease
-
Rohn TT. Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease. Brain Res 2008;1228:189-98
-
(2008)
Brain Res
, vol.1228
, pp. 189-198
-
-
Rohn, T.T.1
-
30
-
-
73549109864
-
Transactive response DNAbinding protein 43 burden in familial Alzheimer disease and Down syndrome
-
Lippa CF, Rosso AL, Stutzbach LD, et al. Transactive response DNAbinding protein 43 burden in familial Alzheimer disease and Down syndrome. Arch Neurol 2009;66:1483-88
-
(2009)
Arch Neurol
, vol.66
, pp. 1483-1488
-
-
Lippa, C.F.1
Rosso, A.L.2
Stutzbach, L.D.3
-
32
-
-
38049018185
-
Biochemical characterization of AA and tau pathologies in mild cognitive impairment and Alzheimer's disease
-
Tremblay C, Pilote M, Phivilay A, et al. Biochemical characterization of AA and tau pathologies in mild cognitive impairment and Alzheimer's disease. J Alzheimers Dis 2007;12:377-90
-
(2007)
J Alzheimers Dis
, vol.12
, pp. 377-390
-
-
Tremblay, C.1
Pilote, M.2
Phivilay, A.3
-
33
-
-
14644416500
-
Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions
-
Bennett DA, Schneider JA, Bienias JL, et al. Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions. Neurology 2005;64:834-41 (Pubitemid 40316322)
-
(2005)
Neurology
, vol.64
, Issue.5
, pp. 834-841
-
-
Bennett, D.A.1
Schneider, J.A.2
Bienias, J.L.3
Evans, D.A.4
Wilson, R.S.5
-
34
-
-
75149192348
-
Neuropathologic alterations in mild cognitive impairment: A review
-
Markesbery WR. Neuropathologic alterations in mild cognitive impairment: A review. J Alzheimers Dis 2010;19:221-28
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 221-228
-
-
Markesbery, W.R.1
-
35
-
-
34247875825
-
Morphological substrates of cognitive decline in nonagenarians and centenarians: A new paradigm?
-
DOI 10.1016/j.jns.2007.01.025, PII S0022510X07000512, Vascular Dementia Proceedings of the Fourth International Congress on Vascular Dementia
-
Imhof A, Kovari E, von Gunten A, et al. Morphological substrates of cognitive decline in nonagenarians and centenarians: A new paradigm? J Neurol Sci 2007;257:72-79 (Pubitemid 46876646)
-
(2007)
Journal of the Neurological Sciences
, vol.257
, Issue.1-2
, pp. 72-79
-
-
Imhof, A.1
Kovari, E.2
Von Gunten, A.3
Gold, G.4
Rivara, C.-B.5
Herrmann, F.R.6
Hof, P.R.7
Bouras, C.8
Giannakopoulos, P.9
-
36
-
-
68949099364
-
Neuropathology-based risk scoring for dementia diagnosis in the elderly
-
Haneuse S, Larson E, Walker R, et al. Neuropathology-based risk scoring for dementia diagnosis in the elderly. J Alzheimers Dis 2009;17:875-85
-
(2009)
J Alzheimers Dis
, vol.17
, pp. 875-885
-
-
Haneuse, S.1
Larson, E.2
Walker, R.3
-
37
-
-
59349092999
-
Criteria for the neuropathological diagnosis of dementing disorders: Routes out of the swamp?
-
Jellinger KA. Criteria for the neuropathological diagnosis of dementing disorders: Routes out of the swamp? Acta Neuropathol 2009;117:101-10
-
(2009)
Acta Neuropathol
, vol.117
, pp. 101-110
-
-
Jellinger, K.A.1
-
38
-
-
64049098761
-
Neuropathology and cognitive impairment in Alzheimer disease: A complex but coherent relationship
-
Nelson PT, Braak H, Markesbery WR. Neuropathology and cognitive impairment in Alzheimer disease: A complex but coherent relationship. J Neuropathol Exp Neurol 2009;68:1-14
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 1-14
-
-
Nelson, P.T.1
Braak, H.2
Markesbery, W.R.3
-
39
-
-
40849101426
-
Epitope mapping of 2E2-D3, a monoclonal antibody directed against human TDP-43
-
Zhang HX, Tanji K, Mori F, et al. Epitope mapping of 2E2-D3, a monoclonal antibody directed against human TDP-43. Neurosci Lett 2008;434: 170-74
-
(2008)
Neurosci Lett
, vol.434
, pp. 170-174
-
-
Zhang, H.X.1
Tanji, K.2
Mori, F.3
-
40
-
-
33747613756
-
Postmortem indices linking risk factors to cognition: Results from the Religious Order Study and the Memory and Aging Project
-
DOI 10.1097/00002093-200607001-00009, PII 0000209320060700100009
-
Bennett DA. Postmortem indices linking risk factors to cognition: Results from the Religious Order Study and the Memory and Aging Project. Alzheimer Dis Assoc Disord 2006;20:S63-68 (Pubitemid 44265853)
-
(2006)
Alzheimer Disease and Associated Disorders
, vol.20
, Issue.SUPPL. 2
-
-
Bennett, D.A.1
-
41
-
-
0037162382
-
Natural history of mild cognitive impairment in older persons
-
Bennett DA, Wilson RS, Schneider JA, et al. Natural history of mild cognitive impairment in older persons. Neurology 2002;59:198-205 (Pubitemid 34779177)
-
(2002)
Neurology
, vol.59
, Issue.2
, pp. 198-205
-
-
Bennett, D.A.1
Wilson, R.S.2
Schneider, J.A.3
Evans, D.A.4
Beckett, L.A.5
Aggarwal, N.T.6
Barnes, L.L.7
Fox, J.H.8
Bach, J.9
-
42
-
-
27544507775
-
The rush memory and aging project: Study design and baseline characteristics of the study cohort
-
DOI 10.1159/000087446
-
Bennett DA, Schneider JA, Buchman AS, et al. The Rush Memory and Aging Project: Study design and baseline characteristics of the study cohort. Neuroepidemiology 2005;25:163-75 (Pubitemid 41540657)
-
(2005)
Neuroepidemiology
, vol.25
, Issue.4
, pp. 163-175
-
-
Bennett, D.A.1
Schneider, J.A.2
Buchman, A.S.3
De Leon, C.M.4
Bienias, J.L.5
Wilson, R.S.6
-
43
-
-
79952590449
-
Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment
-
Wilson RS, Leurgans SE, Boyle PA, et al. Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment. Arch Neurol 2011;68: 351-56
-
(2011)
Arch Neurol
, vol.68
, pp. 351-356
-
-
Wilson, R.S.1
Leurgans, S.E.2
Boyle, P.A.3
-
44
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991;82:239-59
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
45
-
-
0037469076
-
Apolipoprotein E ε4 allele, AD pathology, and the clinical expression of Alzheimer's disease
-
Bennett DA, Wilson RS, Schneider JA, et al. Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease. Neurology 2003;60:246-52 (Pubitemid 36152017)
-
(2003)
Neurology
, vol.60
, Issue.2
, pp. 246-252
-
-
Bennett, D.A.1
Wilson, R.S.2
Schneider, J.A.3
Evans, D.A.4
Aggarwal, N.T.5
Arnold, S.E.6
Cochran, E.J.7
Berry-Kravis, E.8
Bienias, J.L.9
-
46
-
-
0036015012
-
Individual differences in rates of change in cognitive abilities of older persons
-
DOI 10.1037
-
Wilson RS, Beckett LA, Barnes LL, et al. Individual differences in rates of change in cognitive abilities of older persons. Psychol Aging 2002;17: 179-93 (Pubitemid 34568635)
-
(2002)
Psychology and Aging
, vol.17
, Issue.2
, pp. 179-193
-
-
Wilson, R.S.1
Beckett, L.A.2
Barnes, L.L.3
Schneider, J.A.4
Bach, J.5
Evans, D.A.6
Bennett, D.A.7
-
47
-
-
60349096101
-
Reduction of the cerebrovascular volume in a transgenic mouse model of Alzheimer's disease
-
Bourasset F, Ouellet M, Tremblay C, et al. Reduction of the cerebrovascular volume in a transgenic mouse model of Alzheimer's disease. Neuropharmacology 2009;56:808-13
-
(2009)
Neuropharmacology
, vol.56
, pp. 808-813
-
-
Bourasset, F.1
Ouellet, M.2
Tremblay, C.3
-
48
-
-
85040709233
-
Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments
-
Zhang YJ, Gendron TF, Xu YF, et al. Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments. Mol Neurodegener 2010;5:33
-
(2010)
Mol Neurodegener
, vol.5
, pp. 33
-
-
Zhang, Y.J.1
Gendron, T.F.2
Xu, Y.F.3
-
49
-
-
33947503437
-
Cortical biochemistry in MCI and Alzheimer disease: Lack of correlation with clinical diagnosis
-
DOI 10.1212/01.wnl.0000256373.39415.b1, PII 0000611420070306000012
-
Forman MS, Mufson EJ, Leurgans S, et al. Cortical biochemistry in MCI and Alzheimer disease: Lack of correlation with clinical diagnosis. Neurology 2007;68:757-63 (Pubitemid 46667901)
-
(2007)
Neurology
, vol.68
, Issue.10
, pp. 757-763
-
-
Forman, M.S.1
Mufson, E.J.2
Leurgans, S.3
Pratico, D.4
Joyce, S.5
Leight, S.6
Lee, V.M.-Y.7
Trojanowski, J.Q.8
-
50
-
-
77953024802
-
Prevalence of dementia disorders in the oldestold: An autopsy study
-
Jellinger KA, Attems J. Prevalence of dementia disorders in the oldestold: An autopsy study. Acta Neuropathol 2010;119:421-33
-
(2010)
Acta Neuropathol
, vol.119
, pp. 421-433
-
-
Jellinger, K.A.1
Attems, J.2
-
51
-
-
77951879099
-
Thinking outside the box: Alzheimertype neuropathology that does not map directly onto current consensus recommendations
-
Nelson PT, Kukull WA, Frosch MP. Thinking outside the box: Alzheimertype neuropathology that does not map directly onto current consensus recommendations. J Neuropathol Exp Neurol 2010;69:449-54
-
(2010)
J Neuropathol Exp Neurol
, vol.69
, pp. 449-454
-
-
Nelson, P.T.1
Kukull, W.A.2
Frosch, M.P.3
-
52
-
-
48249111377
-
Decreased drebrin mRNA expression in Alzheimer disease: Correlation with tau pathology
-
Julien C, Tremblay C, Bendjelloul F, et al. Decreased drebrin mRNA expression in Alzheimer disease: Correlation with tau pathology. J Neurosci Res 2008;86:2292-302
-
(2008)
J Neurosci Res
, vol.86
, pp. 2292-302
-
-
Julien, C.1
Tremblay, C.2
Bendjelloul, F.3
-
53
-
-
1542268242
-
Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function
-
DOI 10.1001/archneur.61.3.378
-
Bennett DA, Schneider JA, Wilson RS, et al. Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. Arch Neurol 2004;61:378-84 (Pubitemid 38327357)
-
(2004)
Archives of Neurology
, vol.61
, Issue.3
, pp. 378-384
-
-
Bennett, D.A.1
Schneider, J.A.2
Wilson, R.S.3
Bienias, J.L.4
Arnold, S.E.5
-
54
-
-
0038117796
-
Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline
-
Naslund J, Haroutunian V, Mohs R, et al. Correlation between elevated levels of amyloid {beta}-peptide in the brain and cognitive decline. JAMA 2000;283:1571-77 (Pubitemid 30161512)
-
(2000)
Journal of the American Medical Association
, vol.283
, Issue.12
, pp. 1571-1577
-
-
Naslund, J.1
Haroutunian, V.2
Mohs, R.3
Davis, K.L.4
Davies, P.5
Greengard, P.6
Buxbaum, J.D.7
-
55
-
-
52949094629
-
Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis
-
Rutherford NJ, Zhang YJ, Baker M, et al. Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. PLoS Genet 2008;4:e1000193
-
(2008)
PLoS Genet
, vol.4
-
-
Rutherford, N.J.1
Zhang, Y.J.2
Baker, M.3
-
56
-
-
48749088629
-
Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS
-
Inukai Y, Nonaka T, Arai T, et al. Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS. FEBS Lett 2008;582:2899-904
-
(2008)
FEBS Lett
, vol.582
, pp. 2899-904
-
-
Inukai, Y.1
Nonaka, T.2
Arai, T.3
-
57
-
-
77949908515
-
Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy
-
Arai T, Hasegawa M, Nonoka T, et al. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy. Neuropathology 2010;30:170-81
-
(2010)
Neuropathology
, vol.30
, pp. 170-181
-
-
Arai, T.1
Hasegawa, M.2
Nonoka, T.3
-
58
-
-
59249085091
-
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
-
Neumann M, Kwong LK, Lee EB, et al. Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathol 2009;117:137-49
-
(2009)
Acta Neuropathol
, vol.117
, pp. 137-149
-
-
Neumann, M.1
Kwong, L.K.2
Lee, E.B.3
-
59
-
-
0041689948
-
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
DOI 10.1073/pnas.1630428100
-
Gamblin TC, Chen F, Zambrano A, et al. Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proc Natl Acad Sci USA 2003;100:10032-37 (Pubitemid 37087063)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.17
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
LaPointe, N.10
Miller, R.11
Berry, R.W.12
Binder, L.I.13
Cryns, V.L.14
-
60
-
-
0033617402
-
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-[beta] precursor protein and amyloidogenic A [beta] peptide formation
-
Gervais FG, Xu D, Robertson GS, et al. Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-[beta] precursor protein and amyloidogenic A [beta] peptide formation. Cell 1999;97:395-406
-
(1999)
Cell
, vol.97
, pp. 395-406
-
-
Gervais, F.G.1
Xu, D.2
Robertson, G.S.3
-
61
-
-
3242749074
-
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology
-
DOI 10.1172/JCI200420640
-
Rissman RA, Poon WW, Blurton-Jones M, et al. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. J Clin Invest 2004;114:121-30 (Pubitemid 39071651)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.1
, pp. 121-130
-
-
Rissman, R.A.1
Poon, W.W.2
Blurton-Jones, M.3
Oddo, S.4
Torp, R.5
Vitek, M.P.6
LaFerla, F.M.7
Rohn, T.T.8
Cotman, C.W.9
-
62
-
-
0035141757
-
Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease
-
Rohn TT, Head E, Su JH, et al. Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease. Am J Pathol 2001;158:189-98 (Pubitemid 32096484)
-
(2001)
American Journal of Pathology
, vol.158
, Issue.1
, pp. 189-198
-
-
Rohn, T.T.1
Head, E.2
Su, J.H.3
Anderson, A.J.4
Bahr, B.A.5
Cotman, C.W.6
Cribbs, D.H.7
-
63
-
-
0031930313
-
Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease
-
Yang F, Sun X, Beech W, et al. Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease. Am J Pathol 1998;152:379-89 (Pubitemid 28106384)
-
(1998)
American Journal of Pathology
, vol.152
, Issue.2
, pp. 379-389
-
-
Yang, F.1
Sun, X.2
Beech, W.3
Teter, B.4
Wu, S.5
Sigel, J.6
Vinters, H.V.7
Frautschy, S.A.8
Cole, G.M.9
-
64
-
-
24644453571
-
The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death
-
LeBlanc AC. The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death. Curr Alzheimer Res 2005;2:389-402
-
(2005)
Curr Alzheimer Res
, vol.2
, pp. 389-402
-
-
Leblanc, A.C.1
-
65
-
-
67650432367
-
Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin
-
Dormann D, Capell A, Carlson AM, et al. Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin. J Neurochem 2009;110:1082-94
-
(2009)
J Neurochem
, vol.110
, pp. 1082-1094
-
-
Dormann, D.1
Capell, A.2
Carlson, A.M.3
-
66
-
-
78651408754
-
Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes
-
Sephton CF, Cenik C, Kucukural A, et al. Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes. J Biol Chem 2011;286:1204-15
-
(2011)
J Biol Chem
, vol.286
, pp. 1204-1215
-
-
Sephton, C.F.1
Cenik, C.2
Kucukural, A.3
|