DNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions

Nucleic Acids Research

Volumn 44, Issue 19, 2016, Pages 9096-9109

  Lambrughi, Matteo ^a,b   De Gioia, Luca ^c   Gervasio, Francesco Luigi ^d   Lindorff Larsen, Kresten ^b   Nussinov, Ruth ^e,f   Urani, Chiara ^c   Bruschi, Maurizio ^c   Papaleo, Elena ^a,b  

^a Bioinformatics and Registry ^*  (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^f TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA A KINASE; CASPASE 3; CHECKPOINT KINASE 1; CRK LIKE PROTEIN; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 7; IASPP PROTEIN; KU ANTIGEN; P53 BINDING PROTEIN 2; POLO LIKE KINASE 1; PROTEIN; PROTEIN P53; SERINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG; CARRIER PROTEIN; DNA; PROTEIN BINDING;

ARTICLE; BINDING SITE; DNA BINDING; DNA STRUCTURE; DNA TRANSCRIPTION; FREE ENERGY LANDSCAPE; GENE FUNCTION; GENETIC ANALYSIS; GENETIC LINKAGE; MOLECULAR DYNAMICS; POPULATION GENETICS; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROTECTION; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SIMULATION; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; CHEMISTRY; CONFORMATION; GENETIC TRANSCRIPTION; GENETICS; HYDROGEN BOND; METABOLISM; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

BINDING SITES; CARRIER PROTEINS; DNA; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84994624522     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw770     Document Type: Article

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