RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4

Immunity

Volumn 45, Issue 1, 2016, Pages 46-59

  Najjar, Malek ^a   Saleh, Danish ^a   Zelic, Matija ^b   Nogusa, Shoko ^c   Shah, Saumil ^d   Tai, Albert ^d   Finger, Joshua N ^e   Polykratis, Apostolos ^f   Gough, Peter J ^e   Bertin, John ^e   Whalen, Michael J ^g   Pasparakis, Manolis ^f   Balachandran, Siddharth ^c   Kelliher, Michelle ^b   Poltorak, Alexander ^d   Degterev, Alexei ^a,d  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c FOX CHASE CANCER CENTER   (United States)

^d TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e GLAXOSMITHKLINE   (United States)

^f UNIVERSITY OF COLOGNE   (Germany)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CASPASE 8; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN C FOS; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE 1; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE 3; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; RIPK1 PROTEIN, MOUSE; RIPK3 PROTEIN, MOUSE; TICAM-1 PROTEIN, MOUSE; TRANSCRIPTOME; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; BONE MARROW CELL; BONE MARROW DERIVED MACROPHAGE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MESSENGER RNA SYNTHESIS; MOUSE; MYELOID PROGENITOR CELL; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL CULTURE; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; NECROSIS; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CASPASE 8; CELLS, CULTURED; FEMALE; IMMUNITY, INNATE; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NECROSIS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTOME;

EID: 84990858942     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.06.007     Document Type: Article

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