Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  McNamara, Colleen R ^a   Ahuja, Ruchita ^a   Osafo Addo, Awo D ^a   Barrows, Douglas ^a,d   Kettenbach, Arminja ^b   Skidan, Igor ^a   Teng, Xin ^c,e   Cuny, Gregory D ^c   Gerber, Scott ^b   Degterev, Alexei ^a  

^a TUFTS UNIVERSITY   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

^e UNIVERSITY OF HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; JANUS KINASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN KINASE; PROTEIN KINASE B; RECEPTOR INTERACTING PROTEIN 1 KINASE; THREONINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CELL DEATH; CELL STRAIN L 929; CELL TYPE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; INFLAMMATION; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROBLAST; NECROPTOSIS; NONHUMAN; PROTEIN SYNTHESIS; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELL LINE; ENZYME ACTIVATION; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NECROSIS; PHOSPHORYLATION; PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; THREONINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84874559930     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056576     Document Type: Article

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