-
2
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou C.M. (2000) Molecular portraits of human breast tumours. Nature 406, 747-752
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
-
3
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas Network (2012) Comprehensive molecular portraits of human breast tumours. Nature 490, 61-70
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
Cancer Genome Atlas Network1
-
4
-
-
84891748709
-
The two faces of Hippo: Targeting the Hippo pathway for regenerative medicine and cancer treatment
-
Johnson R. and Halder G. (2014) The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment. Nature Reviews Drug Discovery13, 63-79
-
(2014)
Nature Reviews Drug Discovery
, vol.13
, pp. 63-79
-
-
Johnson, R.1
Halder, G.2
-
5
-
-
0028902594
-
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
-
Justice R.W. et al. (1995) The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes & Development 9, 534-546
-
(1995)
Genes & Development
, vol.9
, pp. 534-546
-
-
Justice, R.W.1
-
6
-
-
0028929414
-
Identifying tumor suppressors in genetic mosaics: The Drosophila lats gene encodes a putative protein kinase
-
Xu T. et al. (1995) Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development 121, 1053-1063
-
(1995)
Development
, vol.121
, pp. 1053-1063
-
-
Xu, T.1
-
7
-
-
0141505119
-
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
-
Pantalacci S. et al. (2003) The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila. Nature Cell Biology 5, 921-927
-
(2003)
Nature Cell Biology
, vol.5
, pp. 921-927
-
-
Pantalacci, S.1
-
8
-
-
0141616617
-
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
-
Udan R.S. et al. (2003) Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway. Nature Cell Biology 5, 914-920
-
(2003)
Nature Cell Biology
, vol.5
, pp. 914-920
-
-
Udan, R.S.1
-
9
-
-
0042232429
-
Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
-
Wu S. et al. (2003) Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 114, 445-456
-
(2003)
Cell
, vol.114
, pp. 445-456
-
-
Wu, S.1
-
10
-
-
0142123293
-
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
-
Jia J. et al. (2003) The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis. Genes & Development 17, 2514-2519
-
(2003)
Genes & Development
, vol.17
, pp. 2514-2519
-
-
Jia, J.1
-
11
-
-
0037162714
-
Salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
-
Tapon N. et al. (2002) Salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110, 467-478
-
(2002)
Cell
, vol.110
, pp. 467-478
-
-
Tapon, N.1
-
12
-
-
0042733354
-
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
-
Harvey K.F. (2003) The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 114, 457-467
-
(2003)
Cell
, vol.114
, pp. 457-467
-
-
Harvey, K.F.1
-
13
-
-
30344445706
-
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
-
Hamaratoglu F. et al. (2006) The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol 8, 27-36
-
(2006)
Nat Cell Biol
, vol.8
, pp. 27-36
-
-
Hamaratoglu, F.1
-
14
-
-
36549074631
-
YAP1 increases organ size and expands undifferentiated progenitor cells
-
Camargo F.D. et al. (2007) YAP1 increases organ size and expands undifferentiated progenitor cells. Current Biology 17, 2054-2060
-
(2007)
Current Biology
, vol.17
, pp. 2054-2060
-
-
Camargo, F.D.1
-
15
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
Zhao B. et al. (2007) Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes & Development 21, 2747-2761
-
(2007)
Genes & Development
, vol.21
, pp. 2747-2761
-
-
Zhao, B.1
-
16
-
-
42049116586
-
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
-
Wu S. et al. (2008) The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Developmental Cell 14, 388-398
-
(2008)
Developmental Cell
, vol.14
, pp. 388-398
-
-
Wu, S.1
-
17
-
-
42049120338
-
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
-
Zhang L. et al. (2008) The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Developmental Cell 14, 377-387
-
(2008)
Developmental Cell
, vol.14
, pp. 377-387
-
-
Zhang, L.1
-
18
-
-
70350502865
-
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
-
Zhou D. et al. (2009) Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 16, 425-438
-
(2009)
Cancer Cell
, vol.16
, pp. 425-438
-
-
Zhou, D.1
-
19
-
-
79956327002
-
Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
-
Fernández B.G. et al. (2011) Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila. Development 138, 2337-2346
-
(2011)
Development
, vol.138
, pp. 2337-2346
-
-
Fernández, B.G.1
-
20
-
-
79958851169
-
Modulating F-actin organization induces organ growth by affecting the Hippo pathway
-
Sansores-Garcia L. et al. (2011) Modulating F-actin organization induces organ growth by affecting the Hippo pathway. EMBO J 30, 2325-2335
-
(2011)
EMBO J
, vol.30
, pp. 2325-2335
-
-
Sansores-Garcia, L.1
-
22
-
-
34548636132
-
Elucidation of a universal size-control mechanism in Drosophila and mammals
-
Dong J. et al. (2007) Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 130, 1120-1133
-
(2007)
Cell
, vol.130
, pp. 1120-1133
-
-
Dong, J.1
-
23
-
-
23744458034
-
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP
-
Huang J. et al. (2005) The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP. Cell 122, 421-434
-
(2005)
Cell
, vol.122
, pp. 421-434
-
-
Huang, J.1
-
24
-
-
41149098966
-
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
-
Lei Q.Y. et al. (2008) TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Molecular and Cellular Biology 28, 2426-2436
-
(2008)
Molecular and Cellular Biology
, vol.28
, pp. 2426-2436
-
-
Lei, Q.Y.1
-
26
-
-
84866621687
-
The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway
-
Hong W. and Guan K.L. (2012) The YAP and TAZ transcription co-activators: key downstream effectors of the mammalian Hippo pathway. Seminars in Cell and Developmental Biology 23, 785-793
-
(2012)
Seminars in Cell and Developmental Biology
, vol.23
, pp. 785-793
-
-
Hong, W.1
Guan, K.L.2
-
27
-
-
78549275131
-
The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase
-
Liu C.Y. et al. (2010) The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase. Journal of Biological Chemistry 285, 37159-37169
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 37159-37169
-
-
Liu, C.Y.1
-
28
-
-
73549095761
-
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
-
Zhao B. et al. (2010) A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes & Development 24, 72-85
-
(2010)
Genes & Development
, vol.24
, pp. 72-85
-
-
Zhao, B.1
-
29
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
Dupont S. et al. (2011) Role of YAP/TAZ in mechanotransduction. Nature 474, 179-183
-
(2011)
Nature
, vol.474
, pp. 179-183
-
-
Dupont, S.1
-
30
-
-
84897579255
-
Metabolic control of YAP and TAZ by the mevalonate pathway
-
Sorrentino G. et al. (2014) Metabolic control of YAP and TAZ by the mevalonate pathway. Nature Cell Biology 16, 357-366
-
(2014)
Nature Cell Biology
, vol.16
, pp. 357-366
-
-
Sorrentino, G.1
-
31
-
-
84904043132
-
YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response
-
Azzolin L. et al. (2014) YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response. Cell 158, 157-170
-
(2014)
Cell
, vol.158
, pp. 157-170
-
-
Azzolin, L.1
-
32
-
-
84893721816
-
TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells
-
Bartucci M. et al. (2015) TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells. Oncogene 34, 681-690
-
(2015)
Oncogene
, vol.34
, pp. 681-690
-
-
Bartucci, M.1
-
33
-
-
84930440066
-
The Hippo transducer TAZ as a biomarker of pathological complete response in HER2-positive breast cancer patients treated with trastuzumab-based neoadjuvant therapy
-
Vici P. et al. (2014) The Hippo transducer TAZ as a biomarker of pathological complete response in HER2-positive breast cancer patients treated with trastuzumab-based neoadjuvant therapy. Oncotarget 5, 9619-9625
-
(2014)
Oncotarget
, vol.5
, pp. 9619-9625
-
-
Vici, P.1
-
34
-
-
84894668015
-
Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response
-
Lehn S. et al. (2014) Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response. BMC Cancer 14, 119
-
(2014)
BMC Cancer
, vol.14
, pp. 119
-
-
Lehn, S.1
-
35
-
-
84925538890
-
Metaplastic carcinoma show different expression pattern of YAP compared to triple-negative breast cancer
-
Min Kim H. et al. (2014) Metaplastic carcinoma show different expression pattern of YAP compared to triple-negative breast cancer. Tumor Biology 36, 1207-1212
-
(2014)
Tumor Biology
, vol.36
, pp. 1207-1212
-
-
Min Kim, H.1
-
36
-
-
84904356717
-
Yes-associated protein (YAP) is differentially expressed in tumor and stroma according to the molecular subtype of breast cancer
-
Kim S.K. et al. (2014) Yes-associated protein (YAP) is differentially expressed in tumor and stroma according to the molecular subtype of breast cancer. International Journal of Clinical and Experimental Pathology 7, 3224-3234
-
(2014)
International Journal of Clinical and Experimental Pathology
, vol.7
, pp. 3224-3234
-
-
Kim, S.K.1
-
37
-
-
84897104535
-
The Hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment
-
Skibinski A. et al. (2014) The Hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment. Cell Reports 6, 1059-1072
-
(2014)
Cell Reports
, vol.6
, pp. 1059-1072
-
-
Skibinski, A.1
-
38
-
-
42349088170
-
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells
-
Chan S.W. et al. (2008) A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. Cancer Research 68, 2592-2598
-
(2008)
Cancer Research
, vol.68
, pp. 2592-2598
-
-
Chan, S.W.1
-
39
-
-
67649770134
-
TEADs mediate nuclear retention of TAZ to promote oncogenic transformation
-
Chan S.W. et al. (2009) TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. The Journal of Biological Chemistry 284, 14347-14358
-
(2009)
The Journal of Biological Chemistry
, vol.284
, pp. 14347-14358
-
-
Chan, S.W.1
-
40
-
-
84855404337
-
TAZ antagonizes the WWP1-mediated KLF5 degradation and promotes breast cell proliferation and tumorigenesis
-
Zhao D., Zhi X., Zhou Z. and Chen C. (2012) TAZ antagonizes the WWP1-mediated KLF5 degradation and promotes breast cell proliferation and tumorigenesis. Carcinogenesis 33, 59-67
-
(2012)
Carcinogenesis
, vol.33
, pp. 59-67
-
-
Zhao, D.1
Zhi, X.2
Zhou, Z.3
Chen, C.4
-
41
-
-
79958182034
-
NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway
-
Habbig S. et al. (2011) NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway. The Journal of Cell Biology 193, 633-642
-
(2011)
The Journal of Cell Biology
, vol.193
, pp. 633-642
-
-
Habbig, S.1
-
42
-
-
84870831806
-
The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ
-
Habbig S. et al. (2012) The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. Human Molecular Genetics 21, 5528-5538
-
(2012)
Human Molecular Genetics
, vol.21
, pp. 5528-5538
-
-
Habbig, S.1
-
43
-
-
84900424727
-
The transcriptional regulators TAZ and YAP direct transforming growth factor β-induced tumorigenic phenotypes in breast cancer cells
-
Hiemer S.E., Szymaniak A.D. and Varelas X. (2014) The transcriptional regulators TAZ and YAP direct transforming growth factor β-induced tumorigenic phenotypes in breast cancer cells. Journal of Biological Chemistry 289, 13461-13474
-
(2014)
Journal of Biological Chemistry
, vol.289
, pp. 13461-13474
-
-
Hiemer, S.E.1
Szymaniak, A.D.2
Varelas, X.3
-
45
-
-
84860485144
-
Yes-associated protein promotes tumour development in luminal epithelial derived breast cancer
-
Wang X., Su L. and Ou Q. (2012) Yes-associated protein promotes tumour development in luminal epithelial derived breast cancer. European Journal of Cancer 48, 1227-1234
-
(2012)
European Journal of Cancer
, vol.48
, pp. 1227-1234
-
-
Wang, X.1
Su, L.2
Ou, Q.3
-
46
-
-
84896824055
-
A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis
-
Chen Q. et al. (2014) A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis. Genes & Development 28, 432-437
-
(2014)
Genes & Development
, vol.28
, pp. 432-437
-
-
Chen, Q.1
-
47
-
-
73349128777
-
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
-
Zhang J. et al. (2009) YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nature Cell Biology 11, 1444-1450
-
(2009)
Nature Cell Biology
, vol.11
, pp. 1444-1450
-
-
Zhang, J.1
-
48
-
-
84864541239
-
TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin
-
Yang N. et al. (2012) TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin. Cell Cycle 11, 2922-2930
-
(2012)
Cell Cycle
, vol.11
, pp. 2922-2930
-
-
Yang, N.1
-
49
-
-
84879298347
-
Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer
-
Bendinelli P. et al. (2013) Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer. European Journal of Cancer 49, 2608-2618
-
(2013)
European Journal of Cancer
, vol.49
, pp. 2608-2618
-
-
Bendinelli, P.1
-
51
-
-
84870261155
-
LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker
-
Chen D. et al. (2012) LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker. Nature Medicine 18, 1511-1517
-
(2012)
Nature Medicine
, vol.18
, pp. 1511-1517
-
-
Chen, D.1
-
53
-
-
84878615570
-
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
-
Calvo F. et al. (2013) Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts. Nature Cell Biology 15, 637-646
-
(2013)
Nature Cell Biology
, vol.15
, pp. 637-646
-
-
Calvo, F.1
-
54
-
-
84904024982
-
KRAS and YAP1 converge to regulate EMT and tumor survival
-
Shao D.D. et al. (2014) KRAS and YAP1 converge to regulate EMT and tumor survival. Cell 158, 171-184
-
(2014)
Cell
, vol.158
, pp. 171-184
-
-
Shao, D.D.1
-
55
-
-
84903984143
-
Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer
-
Kapoor A. et al. (2014) Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer. Cell 158, 185-197
-
(2014)
Cell
, vol.158
, pp. 185-197
-
-
Kapoor, A.1
-
56
-
-
0037249343
-
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis
-
Basu S. et al. (2003) Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. Molecular Cell 11, 11-23
-
(2003)
Molecular Cell
, vol.11
, pp. 11-23
-
-
Basu, S.1
-
57
-
-
34748812613
-
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein
-
Matallanas D. et al. (2007) RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein. Molecular Cell 27, 962-975
-
(2007)
Molecular Cell
, vol.27
, pp. 962-975
-
-
Matallanas, D.1
-
58
-
-
21044442524
-
The transcriptional coactivator Yesassociated protein drives p73 gene-target specificity in response to DNA Damage
-
Strano S. et al. (2005) The transcriptional coactivator Yesassociated protein drives p73 gene-target specificity in response to DNA Damage. Molecular Cell 18, 447-459
-
(2005)
Molecular Cell
, vol.18
, pp. 447-459
-
-
Strano, S.1
-
59
-
-
54049121368
-
Yes-associated protein (YAP) functions as a tumor suppressor in breast
-
Yuan M. et al. (2008) Yes-associated protein (YAP) functions as a tumor suppressor in breast. Cell Death & Differentiation 15, 1752-1759
-
(2008)
Cell Death & Differentiation
, vol.15
, pp. 1752-1759
-
-
Yuan, M.1
-
60
-
-
37349005990
-
Yes-associated protein (YAP) is a critical mediator of c-Jun-dependent apoptosis
-
Danovi S.A. et al. (2008) Yes-associated protein (YAP) is a critical mediator of c-Jun-dependent apoptosis. Cell Death & Differentiation 15, 217-219
-
(2008)
Cell Death & Differentiation
, vol.15
, pp. 217-219
-
-
Danovi, S.A.1
-
61
-
-
33947382284
-
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73
-
Levy D. et al. (2007) The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. Cell Death & Differentiation 14, 743-751
-
(2007)
Cell Death & Differentiation
, vol.14
, pp. 743-751
-
-
Levy, D.1
-
62
-
-
0035805487
-
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
-
Strano S. et al. (2001) Physical interaction with Yes-associated protein enhances p73 transcriptional activity. Journal of Biological Chemistry 276, 15164-15173
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 15164-15173
-
-
Strano, S.1
-
63
-
-
0027945323
-
Loss of heterozygosity at 11q22-q23 in breast cancer
-
Carter S.L. et al. (1994) Loss of heterozygosity at 11q22-q23 in breast cancer. Cancer Research 54, 6270-6274
-
(1994)
Cancer Research
, vol.54
, pp. 6270-6274
-
-
Carter, S.L.1
-
64
-
-
0029149274
-
Loss of heterozygosity at chromosome 11 in breast cancer: Association of prognostic factors with genetic alterations
-
Gudmundsson J. et al. (1995) Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations. British Journal of Cancer 72, 696-701
-
(1995)
British Journal of Cancer
, vol.72
, pp. 696-701
-
-
Gudmundsson, J.1
-
65
-
-
0028123002
-
Loss of heterozygosity in sporadic human breast carcinoma: A common region between 11q22 and 11q23.3
-
Hampton G.M. et al. (1994) Loss of heterozygosity in sporadic human breast carcinoma: a common region between 11q22 and 11q23.3. Cancer Research 54, 4586-4589
-
(1994)
Cancer Research
, vol.54
, pp. 4586-4589
-
-
Hampton, G.M.1
-
66
-
-
0029055009
-
Loss of heterozygosity for chromosome 11 in primary human breast tumors is associated with poor survival after metastasis
-
Winqvist R. et al. (1995) Loss of heterozygosity for chromosome 11 in primary human breast tumors is associated with poor survival after metastasis. Cancer Research 55, 2660-2664
-
(1995)
Cancer Research
, vol.55
, pp. 2660-2664
-
-
Winqvist, R.1
-
67
-
-
84875129380
-
MicroRNA-200a promotes anoikis resistance and metastasis by targeting YAP1 in human breast cancer
-
Yu S.J. et al. (2013) MicroRNA-200a promotes anoikis resistance and metastasis by targeting YAP1 in human breast cancer. Clinical Cancer Research 19, 1389-1399
-
(2013)
Clinical Cancer Research
, vol.19
, pp. 1389-1399
-
-
Yu, S.J.1
-
68
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D. and Dick J.E. (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature Medicine 3, 730-737
-
(1997)
Nature Medicine
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
70
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L. et al. (2007) Identification and expansion of human colon-cancer-initiating cells. Nature 445, 111-115
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
-
71
-
-
39449088496
-
Identification and expansion of the tumorigenic lung cancer stem cell population
-
Eramo A. et al. (2008) Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death & Differentiation 15, 504-514
-
(2008)
Cell Death & Differentiation
, vol.15
, pp. 504-514
-
-
Eramo, A.1
-
72
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh S.K. et al. (2004) Identification of human brain tumour initiating cells. Nature 432, 396-401
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
-
73
-
-
78449281896
-
Tumorigenic and metastatic activity of human thyroid cancer stem cells
-
TodaroM. et al. (2010) Tumorigenic and metastatic activity of human thyroid cancer stem cells. Cancer Research 70, 8874-8885
-
(2010)
Cancer Research
, vol.70
, pp. 8874-8885
-
-
Todaro, M.1
-
74
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties inhead and neck squamous cell carcinoma
-
Prince M.E. et al. (2007) Identification of a subpopulation of cells with cancer stem cell properties inhead and neck squamous cell carcinoma. Proceedings of the National Academy of Sciences of the United States of America 104, 973-978
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 973-978
-
-
Prince, M.E.1
-
75
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C. et al. (2007) Identification of pancreatic cancer stem cells. Cancer Research 67, 1030-1037
-
(2007)
Cancer Research
, vol.67
, pp. 1030-1037
-
-
Li, C.1
-
76
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
Collins A.T. et al. (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer Research 65, 10946-10951
-
(2005)
Cancer Research
, vol.65
, pp. 10946-10951
-
-
Collins, A.T.1
-
77
-
-
77952240931
-
CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells
-
Gao M.Q. et al. (2010) CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells. Oncogene 29, 2672-2680
-
(2010)
Oncogene
, vol.29
, pp. 2672-2680
-
-
Gao, M.Q.1
-
78
-
-
84856013431
-
Clonal evolution in cancer
-
GreavesM. and Maley C.C. (2012) Clonal evolution in cancer. Nature 481, 306-313
-
(2012)
Nature
, vol.481
, pp. 306-313
-
-
Greaves, M.1
Maley, C.C.2
-
79
-
-
80053904142
-
Distinct types of tumor-initiating cells form human colon cancer tumors and metastases
-
Dieter S.M. et al. (2011) Distinct types of tumor-initiating cells form human colon cancer tumors and metastases. Cell Stem Cell 9, 357-365
-
(2011)
Cell Stem Cell
, vol.9
, pp. 357-365
-
-
Dieter, S.M.1
-
80
-
-
65049084510
-
Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution
-
Piccirillo S.G. et al. (2009) Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution. Oncogene 28, 1807-1811
-
(2009)
Oncogene
, vol.28
, pp. 1807-1811
-
-
Piccirillo, S.G.1
-
81
-
-
78751644099
-
Genetic variegation of clonal architecture and propagating cells in leukaemia
-
Anderson K. et al. (2011) Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 469, 356-361
-
(2011)
Nature
, vol.469
, pp. 356-361
-
-
Anderson, K.1
-
82
-
-
78751661556
-
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
-
Notta F. et al. (2011) Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature 469, 362-367
-
(2011)
Nature
, vol.469
, pp. 362-367
-
-
Notta, F.1
-
83
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani S.A. et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133, 704-715
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
-
84
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
Li Z. et al. (2009) Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 15, 501-513
-
(2009)
Cancer Cell
, vol.15
, pp. 501-513
-
-
Li, Z.1
-
85
-
-
79954423356
-
Acidic stress promotes a glioma stem cell phenotype
-
Hjelmeland A.B. et al. (2011) Acidic stress promotes a glioma stem cell phenotype. Cell Death & Differentiation 18, 829-840
-
(2011)
Cell Death & Differentiation
, vol.18
, pp. 829-840
-
-
Hjelmeland, A.B.1
-
86
-
-
84896115102
-
CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis
-
Todaro M. et al. (2014) CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis. Cell Stem Cell 14, 342-356
-
(2014)
Cell Stem Cell
, vol.14
, pp. 342-356
-
-
Todaro, M.1
-
87
-
-
84901774050
-
The Hippo signaling pathway in stem cell biology and cancer
-
Mo J.S., Park H.W. and Guan K.L. (2014) The Hippo signaling pathway in stem cell biology and cancer. EMBO Reports 15, 642-656
-
(2014)
EMBO Reports
, vol.15
, pp. 642-656
-
-
Mo, J.S.1
Park, H.W.2
Guan, K.L.3
-
88
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi M. et al. (2011) The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell 147, 759-772
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
-
90
-
-
79953310106
-
Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF
-
Lai D., Ho K.C., Hao Y. and Yang X. (2011) Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Research 71, 2728-2738
-
(2011)
Cancer Research
, vol.71
, pp. 2728-2738
-
-
Lai, D.1
Ho, K.C.2
Hao, Y.3
Yang, X.4
-
91
-
-
84929454867
-
Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis
-
Li Y.W. et al. (2015) Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis. Cell Cycle 14, 146-156
-
(2015)
Cell Cycle
, vol.14
, pp. 146-156
-
-
Li, Y.W.1
-
92
-
-
84921374070
-
Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype
-
Xiang L. et al. (2014) Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype. Oncotarget 5, 12509-12527
-
(2014)
Oncotarget
, vol.5
, pp. 12509-12527
-
-
Xiang, L.1
-
93
-
-
84920450458
-
A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6Bβ1 integrin to sustain breast cancer stem cells
-
Chang C. et al. (2015) A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6Bβ1 integrin to sustain breast cancer stem cells. Genes & Development 29, 1-6
-
(2015)
Genes & Development
, vol.29
, pp. 1-6
-
-
Chang, C.1
-
94
-
-
84920031404
-
Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets
-
Frangou C. et al. (2014) Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets. Oncotarget 5, 12166-12176
-
(2014)
Oncotarget
, vol.5
, pp. 12166-12176
-
-
Frangou, C.1
-
97
-
-
81555216077
-
Gene expression profiling in breast cancer: Classification, prognostication, and prediction
-
Reis-Filho J.S. and Pusztai L. (2011) Gene expression profiling in breast cancer: classification, prognostication, and prediction. Lancet 378, 1812-1823
-
(2011)
Lancet
, vol.378
, pp. 1812-1823
-
-
Reis-Filho, J.S.1
Pusztai, L.2
-
98
-
-
84890916735
-
Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase
-
Serrano I. et al. (2013) Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. Nature Communications 4, 2976
-
(2013)
Nature Communications
, vol.4
, pp. 2976
-
-
Serrano, I.1
-
99
-
-
84871425210
-
Bone metastatic process of breast cancer involves methylation state affecting E-cadherin expression through TAZ and WWOX nuclear effectors
-
Matteucci E. et al. (2013) Bone metastatic process of breast cancer involves methylation state affecting E-cadherin expression through TAZ and WWOX nuclear effectors. European Journal of Cancer 49, 231-244
-
(2013)
European Journal of Cancer
, vol.49
, pp. 231-244
-
-
Matteucci, E.1
-
100
-
-
84857236823
-
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): A randomised, open-label, multicentre, phase 3 trial
-
Baselga J. et al. (2012) Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial. Lancet 379, 633-640
-
(2012)
Lancet
, vol.379
, pp. 633-640
-
-
Baselga, J.1
-
101
-
-
84856444501
-
Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): A randomised phase 3 trial
-
Untch M. et al. (2012) Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial. The Lancet Oncology 13, 135-144
-
(2012)
The Lancet Oncology
, vol.13
, pp. 135-144
-
-
Untch, M.1
-
102
-
-
84855297353
-
Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): A randomised multicentre, open-label, phase 2 trial
-
Gianni L. et al. (2012) Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. The Lancet Oncology 13, 25-32
-
(2012)
The Lancet Oncology
, vol.13
, pp. 25-32
-
-
Gianni, L.1
-
103
-
-
84861553242
-
BIG-NABCG collaboration. A common language in neoadjuvant breast cancer clinical trials: Proposals for standard definitions and endpoints
-
Fumagalli D. (2012) BIG-NABCG collaboration. A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints. The Lancet Oncology 13, e240-248
-
(2012)
The Lancet Oncology
, vol.13
, pp. e240-248
-
-
Fumagalli, D.1
-
104
-
-
84862605178
-
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
-
Liu-Chittenden Y. et al. (2012) Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes & Development 26, 1300-1305
-
(2012)
Genes & Development
, vol.26
, pp. 1300-1305
-
-
Liu-Chittenden, Y.1
-
105
-
-
84902515862
-
Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP
-
Yu F.X. et al. (2014) Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP. Cancer Cell 25, 822-830
-
(2014)
Cancer Cell
, vol.25
, pp. 822-830
-
-
Yu, F.X.1
-
106
-
-
79961063553
-
A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription
-
Bao Y. et al. (2011) A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription. The Journal of Biochemistry 150, 199-208
-
(2011)
The Journal of Biochemistry
, vol.150
, pp. 199-208
-
-
Bao, Y.1
-
107
-
-
84871576111
-
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis
-
Rosenbluh J. et al. (2012) β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell 151, 1457-1473
-
(2012)
Cell
, vol.151
, pp. 1457-1473
-
-
Rosenbluh, J.1
-
108
-
-
84891940884
-
Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility
-
Wang Z. et al. (2014) Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility. Proceedings of the National Academy of Sciences of the United States of America 111, E89-E98
-
(2014)
Proceedings of the National Academy of Sciences of the United States of America
, vol.111
, pp. E89-E98
-
-
Wang, Z.1
|