-
2
-
-
0037162714
-
Salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
-
Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber D, Hariharan IK. Salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell. 2002;110:467-478.
-
(2002)
Cell
, vol.110
, pp. 467-478
-
-
Tapon, N.1
Harvey, K.F.2
Bell, D.W.3
Wahrer, D.C.4
Schiripo, T.A.5
Haber, D.6
Hariharan, I.K.7
-
3
-
-
0028902594
-
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
-
Justice RW, Zilian O, Woods DF, Noll M, Bryant PJ. The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev.;9:534-546.
-
Genes Dev
, vol.9
, pp. 534-546
-
-
Justice, R.W.1
Zilian, O.2
Woods, D.F.3
Noll, M.4
Bryant, P.J.5
-
4
-
-
36549074631
-
YAP1 increases organ size and expands undifferentiated progenitor cells
-
Camargo FD, Gokhale S, Johnnidis JB, Fu D, Bell GW, Jaenisch R, Brummelkamp TR. YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol. 2007;17:2054-2060.
-
(2007)
Curr Biol
, vol.17
, pp. 2054-2060
-
-
Camargo, F.D.1
Gokhale, S.2
Johnnidis, J.B.3
Fu, D.4
Bell, G.W.5
Jaenisch, R.6
Brummelkamp, T.R.7
-
5
-
-
84891748709
-
The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment
-
Johnson R, Halder G. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment. Nat Rev Drug Discov. 2014;13:63-79.
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 63-79
-
-
Johnson, R.1
Halder, G.2
-
6
-
-
84904043132
-
YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
-
Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, Bresolin S, Frasson C, Basso G, Guzzardo V, Fassina A, Cordenonsi M, Piccolo S. YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response. Cell. 2014;158:157-170.
-
(2014)
Cell
, vol.158
, pp. 157-170
-
-
Azzolin, L.1
Panciera, T.2
Soligo, S.3
Enzo, E.4
Bicciato, S.5
Dupont, S.6
Bresolin, S.7
Frasson, C.8
Basso, G.9
Guzzardo, V.10
Fassina, A.11
Cordenonsi, M.12
Piccolo, S.13
-
7
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, et al. The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell. 2011;147:759-772.
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
Forcato, M.4
Rosato, A.5
Frasson, C.6
Inui, M.7
Montagner, M.8
Parenti, A.R.9
Poletti, A.10
Daidone, M.G.11
Dupont, S.12
Basso, G.13
-
8
-
-
84893721816
-
TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells
-
[Epub ahead of print] Feb 17
-
Bartucci M, Dattilo R, Moriconi C, Pagliuca A, Mottolese M, Federici G, Benedetto AD, Todaro M, Stassi G, Sperati F, Amabile MI, Pilozzi E, Patrizii M, et al. TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells. Oncogene. 2014 Feb 17. doi: 10.1038/onc.2014.5. [Epub ahead of print]
-
(2014)
Oncogene
-
-
Bartucci, M.1
Dattilo, R.2
Moriconi, C.3
Pagliuca, A.4
Mottolese, M.5
Federici, G.6
Benedetto, A.D.7
Todaro, M.8
Stassi, G.9
Sperati, F.10
Amabile, M.I.11
Pilozzi, E.12
Patrizii, M.13
-
10
-
-
84883477300
-
Patient-derived tumor xenografts: transforming clinical samples into mouse models
-
Siolas D, Hannon GJ. Patient-derived tumor xenografts: transforming clinical samples into mouse models. Cancer Res. 2013;73:5315-5319.
-
(2013)
Cancer Res
, vol.73
, pp. 5315-5319
-
-
Siolas, D.1
Hannon, G.J.2
-
11
-
-
77955268969
-
New models for cancer research: human cancer stem cell xenografts
-
Baiocchi M, Biffoni M, Ricci-Vitiani L, Pilozzi E, De Maria R. New models for cancer research: human cancer stem cell xenografts. Curr Opin Pharmacol. 2010;10:380-384.
-
(2010)
Curr Opin Pharmacol
, vol.10
, pp. 380-384
-
-
Baiocchi, M.1
Biffoni, M.2
Ricci-Vitiani, L.3
Pilozzi, E.4
De Maria, R.5
-
12
-
-
81555216077
-
Gene expression profiling in breast cancer: classification, prognostication, and prediction
-
Reis-Filho JS, Pusztai L. Gene expression profiling in breast cancer: classification, prognostication, and prediction. Lancet. 2011;378:1812-1823.
-
(2011)
Lancet
, vol.378
, pp. 1812-1823
-
-
Reis-Filho, J.S.1
Pusztai, L.2
-
13
-
-
85039889573
-
-
NCCN Clinical Practice Guidelines in Oncology: Breast Cancer, Version 3
-
NCCN Clinical Practice Guidelines in Oncology: Breast Cancer, Version 3.2014. Available at: http://www.nccn.org/professionals/physician_gls/f_guidelines.asp
-
(2014)
-
-
-
14
-
-
77957883342
-
The hippo signaling pathway in development and cancer
-
Pan D. The hippo signaling pathway in development and cancer. Dev Cell. 2010;19:491-505.
-
(2010)
Dev Cell
, vol.19
, pp. 491-505
-
-
Pan, D.1
-
15
-
-
84861553242
-
BIG-NABCG collaboration A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints
-
Fumagalli D, Bedard PL, Nahleh Z, Michiels S, Sotiriou C, Loi S, Sparano JA, Ellis M, Hylton N, Zujewski JA, Hudis C, Esserman L, Piccart M; BIG-NABCG collaboration. A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints. Lancet Oncol. 2012;13:e240-248.
-
(2012)
Lancet Oncol
, vol.13
, pp. e240-248
-
-
Fumagalli, D.1
Bedard, P.L.2
Nahleh, Z.3
Michiels, S.4
Sotiriou, C.5
Loi, S.6
Sparano, J.A.7
Ellis, M.8
Hylton, N.9
Zujewski, J.A.10
Hudis, C.11
Esserman, L.12
Piccart, M.13
-
16
-
-
84892776195
-
Research-based PAM50 subtype predictor identifies higher responses and improved survival outcomes in HER2-positive breast cancer in the NOAH study
-
Prat A, Bianchini G, Thomas M, Belousov A, Cheang MC, Koehler A, Gómez P, Semiglazov V, Eiermann W, Tjulandin S, Byakhow M, Bermejo B, Zambetti M, et al. Research-based PAM50 subtype predictor identifies higher responses and improved survival outcomes in HER2-positive breast cancer in the NOAH study. Clin Cancer Res. 2014;20:511-521.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 511-521
-
-
Prat, A.1
Bianchini, G.2
Thomas, M.3
Belousov, A.4
Cheang, M.C.5
Koehler, A.6
Gómez, P.7
Semiglazov, V.8
Eiermann, W.9
Tjulandin, S.10
Byakhow, M.11
Bermejo, B.12
Zambetti, M.13
-
17
-
-
84880230412
-
Somatic mutation profiling and associations with prognosis and trastuzumab benefit in early breast cancer
-
Loi S, Michiels S, Lambrechts D, Fumagalli D, Claes B, Kellokumpu-Lehtinen PL, Bono P, Kataja V, Piccart MJ, Joensuu H, Sotiriou C. Somatic mutation profiling and associations with prognosis and trastuzumab benefit in early breast cancer. J Natl Cancer Inst. 2013;105:960-967.
-
(2013)
J Natl Cancer Inst
, vol.105
, pp. 960-967
-
-
Loi, S.1
Michiels, S.2
Lambrechts, D.3
Fumagalli, D.4
Claes, B.5
Kellokumpu-Lehtinen, P.L.6
Bono, P.7
Kataja, V.8
Piccart, M.J.9
Joensuu, H.10
Sotiriou, C.11
-
18
-
-
84886408077
-
Impact of PTEN protein expression on benefit from adjuvant trastuzumab in early-stage human epidermal growth factor receptor 2-positive breast cancer in the North Central Cancer Treatment Group N9831 trial
-
Perez EA, Dueck AC, McCullough AE, Chen B, Geiger XJ, Jenkins RB, Lingle WL, Davidson NE, Martino S, Kaufman PA, Kutteh LA, Sledge GW, Harris LN, et al. Impact of PTEN protein expression on benefit from adjuvant trastuzumab in early-stage human epidermal growth factor receptor 2-positive breast cancer in the North Central Cancer Treatment Group N9831 trial. J Clin Oncol. 2013;31:2115-2122.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2115-2122
-
-
Perez, E.A.1
Dueck, A.C.2
McCullough, A.E.3
Chen, B.4
Geiger, X.J.5
Jenkins, R.B.6
Lingle, W.L.7
Davidson, N.E.8
Martino, S.9
Kaufman, P.A.10
Kutteh, L.A.11
Sledge, G.W.12
Harris, L.N.13
-
19
-
-
34247588567
-
Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer
-
Scaltriti M1, Rojo F, Ocaña A, Anido J, Guzman M, Cortes J, Di Cosimo S, Matias-Guiu X, Ramon y Cajal S, Arribas J, Baselga J. Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer. J Natl Cancer Inst. 2007;99:628-638.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 628-638
-
-
Scaltriti, M11
Rojo, F.2
Ocaña, A.3
Anido, J.4
Guzman, M.5
Cortes, J.6
Di Cosimo, S.7
Matias-Guiu, X.8
Ramon y Cajal, S.9
Arribas, J.10
Baselga, J.11
-
20
-
-
84857236823
-
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial
-
Baselga J1, Bradbury I, Eidtmann H, Di Cosimo S, de Azambuja E, Aura C, Gómez H, Dinh P, Fauria K, Van Dooren V, Aktan G, Goldhirsch A, Chang TW, et al. Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial. Lancet 2012;379:633-640.
-
(2012)
Lancet
, vol.379
, pp. 633-640
-
-
Baselga, J11
Bradbury, I.2
Eidtmann, H.3
Di Cosimo, S.4
de Azambuja, E.5
Aura, C.6
Gómez, H.7
Dinh, P.8
Fauria, K.9
Van Dooren, V.10
Aktan, G.11
Goldhirsch, A.12
Chang, T.W.13
-
21
-
-
84856444501
-
Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto GBG 44): a randomised phase 3 trial
-
Untch M1, Loibl S, Bischoff J, Eidtmann H, Kaufmann M, Blohmer JU, Hilfrich J, Strumberg D, Fasching PA, Kreienberg R, Tesch H, Hanusch C, Gerber B, et al. Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial. Lancet Oncol. 2012;13:135-144.
-
(2012)
Lancet Oncol
, vol.13
, pp. 135-144
-
-
Untch, M.1
Loibl, S.2
Bischoff, J.3
Eidtmann, H.4
Kaufmann, M.5
Blohmer, J.U.6
Hilfrich, J.7
Strumberg, D.8
Fasching, P.A.9
Kreienberg, R.10
Tesch, H.11
Hanusch, C.12
Gerber, B.13
-
22
-
-
84855297353
-
Staroslawska E, de la Haba-Rodriguez J, Im SA, Pedrini JL, Poirier B, Morandi P, et al. Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial
-
Gianni L, Pienkowski T, Im YH, Roman L, Tseng LM, Liu MC, Lluch A, Staroslawska E, de la Haba-Rodriguez J, Im SA, Pedrini JL, Poirier B, Morandi P, et al. Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncol. 2012;13:25-32.
-
(2012)
Lancet Oncol
, vol.13
, pp. 25-32
-
-
Gianni, L.1
Pienkowski, T.2
Im, Y.H.3
Roman, L.4
Tseng, L.M.5
Liu, M.C.6
Lluch, A.7
-
23
-
-
84890254448
-
Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
-
Wolff AC, Hammond ME, Hicks DG, Dowsett M, McShane LM, Allison KH, Allred DC, Barlett JM, Bilous M, Fitzgibbons P, Hanna W, Jenkins RB, Mangu PB, et al. Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update. J Clin Oncol. 2013; 31:3997-4013.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3997-4013
-
-
Wolff, A.C.1
Hammond, M.E.2
Hicks, D.G.3
Dowsett, M.4
McShane, L.M.5
Allison, K.H.6
Allred, D.C.7
Barlett, J.M.8
Bilous, M.9
Fitzgibbons, P.10
Hanna, W.11
Jenkins, R.B.12
Mangu, P.B.13
|