메뉴 건너뛰기




Volumn 94, Issue , 2016, Pages 736-757

Antibiotics in the aquatic environments: A review of the European scenario

Author keywords

Antibiotic resistance; Antibiotics; Aquatic ecotoxicity; Aquatic environment; European scenario; Multiresidue analysis

Indexed keywords

BIOCHEMISTRY; VETERINARY MEDICINE; WATER QUALITY;

EID: 84989350606     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2016.06.025     Document Type: Review
Times cited : (1010)

References (301)
  • 1
    • 84930624495 scopus 로고    scopus 로고
    • Adsorptive removal of antibiotics from water and wastewater: progress and challenges
    • Ahmed, M.B., Zhou, J.L., Ngo, H.H., Guo, W., Adsorptive removal of antibiotics from water and wastewater: progress and challenges. Sci. Total Environ. 532 (2015), 112–126, 10.1016/j.scitotenv.2015.05.130.
    • (2015) Sci. Total Environ. , vol.532 , pp. 112-126
    • Ahmed, M.B.1    Zhou, J.L.2    Ngo, H.H.3    Guo, W.4
  • 2
    • 84865828847 scopus 로고    scopus 로고
    • Monitoring release of pharmaceutical compounds: occurrence and environmental risk assessment of two WWTP effluents and their receiving bodies in the Po Valley, Italy
    • Al Aukidy, M., Verlicchi, P., Jelic, A., et al. Monitoring release of pharmaceutical compounds: occurrence and environmental risk assessment of two WWTP effluents and their receiving bodies in the Po Valley, Italy. Sci. Total Environ. 438 (2012), 15–25, 10.1016/j.scitotenv.2012.08.061.
    • (2012) Sci. Total Environ. , vol.438 , pp. 15-25
    • Al Aukidy, M.1    Verlicchi, P.2    Jelic, A.3
  • 3
    • 26444491047 scopus 로고    scopus 로고
    • Resistance to antibiotics: Are we in the post-antibiotic era?
    • Alanis, A.J., Resistance to antibiotics: Are we in the post-antibiotic era?. Arch. Med. Res. 36 (2005), 697–705, 10.1016/j.arcmed.2005.06.009.
    • (2005) Arch. Med. Res. , vol.36 , pp. 697-705
    • Alanis, A.J.1
  • 4
    • 84941260912 scopus 로고    scopus 로고
    • Ultrasound-assisted extraction of emerging contaminants from environmental samples
    • Albero, B., Sánchez-Brunete, C., García-Valcárcel, A.I., et al. Ultrasound-assisted extraction of emerging contaminants from environmental samples. TrAC Trends Anal. Chem. 71 (2015), 110–118, 10.1016/j.trac.2015.03.015.
    • (2015) TrAC Trends Anal. Chem. , vol.71 , pp. 110-118
    • Albero, B.1    Sánchez-Brunete, C.2    García-Valcárcel, A.I.3
  • 5
    • 84944128272 scopus 로고    scopus 로고
    • Occurrence and spatial distribution of 158 pharmaceuticals, drugs of abuse and related metabolites in offshore seawater
    • Alygizakis, N.A., Ferrero, P.G., Borova, V.L., et al. Occurrence and spatial distribution of 158 pharmaceuticals, drugs of abuse and related metabolites in offshore seawater. Sci. Total Environ. 541 (2016), 1097–1105, 10.1016/j.scitotenv.2015.09.145.
    • (2016) Sci. Total Environ. , vol.541 , pp. 1097-1105
    • Alygizakis, N.A.1    Ferrero, P.G.2    Borova, V.L.3
  • 6
    • 0035054726 scopus 로고    scopus 로고
    • Comparative pharmacokinetics and pharmacodynamics of the newer fluoroquinolone antibacterials
    • Aminimanizani, A., Beringer, P., Jelliffe, R., Comparative pharmacokinetics and pharmacodynamics of the newer fluoroquinolone antibacterials. Clin. Pharmacokinet. 40 (2001), 169–187, 10.2165/00003088-200140030-00003.
    • (2001) Clin. Pharmacokinet. , vol.40 , pp. 169-187
    • Aminimanizani, A.1    Beringer, P.2    Jelliffe, R.3
  • 7
    • 79960399031 scopus 로고    scopus 로고
    • A brief history of the antibiotic era: lessons learned and challenges for the future
    • Aminov, R.I., A brief history of the antibiotic era: lessons learned and challenges for the future. Front. Microbiol. 1 (2010), 1–7, 10.3389/fmicb.2010.00134.
    • (2010) Front. Microbiol. , vol.1 , pp. 1-7
    • Aminov, R.I.1
  • 8
    • 0037369490 scopus 로고    scopus 로고
    • Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment
    • Andreozzi, R., Raffaele, M., Nicklas, P., Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment. Chemosphere 50 (2003), 1319–1330, 10.1016/S0045-6535(02)00769-5.
    • (2003) Chemosphere , vol.50 , pp. 1319-1330
    • Andreozzi, R.1    Raffaele, M.2    Nicklas, P.3
  • 9
    • 10644265358 scopus 로고    scopus 로고
    • Antibiotics in the environment: occurrence in Italian STPs, fate, and preliminary assessment on algal toxicity of amoxicillin
    • Andreozzi, R., Caprio, V., Ciniglia, C., et al. Antibiotics in the environment: occurrence in Italian STPs, fate, and preliminary assessment on algal toxicity of amoxicillin. Environ. Sci. Technol. 38 (2004), 6832–6838, 10.1021/es049509a.
    • (2004) Environ. Sci. Technol. , vol.38 , pp. 6832-6838
    • Andreozzi, R.1    Caprio, V.2    Ciniglia, C.3
  • 10
    • 84989305305 scopus 로고    scopus 로고
    • Antibiotic resistance: a concern to veterinary and human medicine
    • Aryal, S., Antibiotic resistance: a concern to veterinary and human medicine. Nepal Agric. Res. J. 4&5 (2001), 66–70, 10.3126/narj.v4i0.487.
    • (2001) Nepal Agric. Res. J. , vol.4&5 , pp. 66-70
    • Aryal, S.1
  • 11
    • 33748977276 scopus 로고    scopus 로고
    • Solid phase extraction and HPLC determination of veterinary pharmaceuticals in wastewater
    • Babić, S., Asperger, D., Mutavdzić, D., et al. Solid phase extraction and HPLC determination of veterinary pharmaceuticals in wastewater. Talanta 70 (2006), 732–738, 10.1016/j.talanta.2006.07.003.
    • (2006) Talanta , vol.70 , pp. 732-738
    • Babić, S.1    Asperger, D.2    Mutavdzić, D.3
  • 12
    • 27744494137 scopus 로고    scopus 로고
    • Antibiotic resistance in Staphylococcus aureus and its relevance in therapy
    • Bal, A.M., Gould, I.M., Antibiotic resistance in Staphylococcus aureus and its relevance in therapy. Expert. Opin. Pharmacother. 6 (2005), 2257–2269, 10.1517/14656566.6.13.2257.
    • (2005) Expert. Opin. Pharmacother. , vol.6 , pp. 2257-2269
    • Bal, A.M.1    Gould, I.M.2
  • 13
    • 46549084570 scopus 로고    scopus 로고
    • Antibiotics and antibiotic resistance in water environments
    • Baquero, F., Martínez, J.L., Cantón, R., Antibiotics and antibiotic resistance in water environments. Curr. Opin. Biotechnol. 19 (2008), 260–265, 10.1016/j.copbio.2008.05.006.
    • (2008) Curr. Opin. Biotechnol. , vol.19 , pp. 260-265
    • Baquero, F.1    Martínez, J.L.2    Cantón, R.3
  • 14
    • 0033653688 scopus 로고    scopus 로고
    • The impact of antibiotic use on resistance development and persistence
    • Barbosa, T.M., Levy, S.B., The impact of antibiotic use on resistance development and persistence. Drug Resist. Updat. 3 (2000), 303–311, 10.1054/drup.2000.0167.
    • (2000) Drug Resist. Updat. , vol.3 , pp. 303-311
    • Barbosa, T.M.1    Levy, S.B.2
  • 15
    • 0021154432 scopus 로고
    • The structure and mode of action of glycopeptide antibiotics of the vancomycin group
    • Barna, J.C., Williams, D.H., The structure and mode of action of glycopeptide antibiotics of the vancomycin group. Annu. Rev. Microbiol. 38 (1984), 339–357, 10.1146/annurev.mi.38.100184.002011.
    • (1984) Annu. Rev. Microbiol. , vol.38 , pp. 339-357
    • Barna, J.C.1    Williams, D.H.2
  • 16
    • 48649089621 scopus 로고    scopus 로고
    • A national reconnaissance of pharmaceuticals and other organic wastewater contaminants in the United States-I) groundwater
    • Barnes, K.K., Kolpin, D.W., Furlong, E.T., et al. A national reconnaissance of pharmaceuticals and other organic wastewater contaminants in the United States-I) groundwater. Sci. Total Environ. 402 (2008), 192–200, 10.1016/j.scitotenv.2008.04.028.
    • (2008) Sci. Total Environ. , vol.402 , pp. 192-200
    • Barnes, K.K.1    Kolpin, D.W.2    Furlong, E.T.3
  • 17
    • 84877294743 scopus 로고    scopus 로고
    • Seven ways to preserve the miracle of antibiotics
    • Bartlett, J.G., Gilbert, D.N., Spellberg, B., Seven ways to preserve the miracle of antibiotics. Clin. Infect. Dis. 56 (2013), 1445–1450, 10.1093/cid/cit070.
    • (2013) Clin. Infect. Dis. , vol.56 , pp. 1445-1450
    • Bartlett, J.G.1    Gilbert, D.N.2    Spellberg, B.3
  • 18
    • 84912118650 scopus 로고    scopus 로고
    • Aquatic toxicity of the macrolide antibiotic clarithromycin and its metabolites
    • Baumann, M., Weiss, K., Maletzki, D., et al. Aquatic toxicity of the macrolide antibiotic clarithromycin and its metabolites. Chemosphere 120 (2015), 192–198, 10.1016/j.chemosphere.2014.05.089.
    • (2015) Chemosphere , vol.120 , pp. 192-198
    • Baumann, M.1    Weiss, K.2    Maletzki, D.3
  • 19
    • 84922054045 scopus 로고    scopus 로고
    • Antibiotics/antibacterial drug use, their marketing and promotion during the post-antibiotic golden age and their role in emergence of bacterial resistance
    • Bbosa, G.S., Mwebaza, N., Odda, J., et al. Antibiotics/antibacterial drug use, their marketing and promotion during the post-antibiotic golden age and their role in emergence of bacterial resistance. Health (Irvine Calif) 6 (2014), 410–425, 10.4236/health.2014.65059.
    • (2014) Health (Irvine Calif) , vol.6 , pp. 410-425
    • Bbosa, G.S.1    Mwebaza, N.2    Odda, J.3
  • 20
    • 84927610352 scopus 로고    scopus 로고
    • Antibiotic use and emerging resistance: how can resource-limited countries turn the tide?
    • Bebell, L.M., Muiru, A.N., Antibiotic use and emerging resistance: how can resource-limited countries turn the tide?. Glob. Heart 9 (2014), 347–358, 10.1016/j.gheart.2014.08.009.
    • (2014) Glob. Heart , vol.9 , pp. 347-358
    • Bebell, L.M.1    Muiru, A.N.2
  • 21
    • 84900561481 scopus 로고    scopus 로고
    • Emerging contaminants: a scientific challenge without borders
    • Bellenger, J.P., Cabana, H., Emerging contaminants: a scientific challenge without borders. Sci. Total Environ., 487, 2014, 747, 10.1016/j.scitotenv.2014.05.031.
    • (2014) Sci. Total Environ. , vol.487 , pp. 747
    • Bellenger, J.P.1    Cabana, H.2
  • 22
    • 20444435797 scopus 로고    scopus 로고
    • Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Höje River in Sweden
    • Bendz, D., Paxéus, N.A., Ginn, T.R., Loge, F.J., Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Höje River in Sweden. J. Hazard. Mater. 122 (2005), 195–204, 10.1016/j.jhazmat.2005.03.012.
    • (2005) J. Hazard. Mater. , vol.122 , pp. 195-204
    • Bendz, D.1    Paxéus, N.A.2    Ginn, T.R.3    Loge, F.J.4
  • 23
    • 84979847575 scopus 로고    scopus 로고
    • Old and new glycopeptide antibiotics: action and resistance
    • Binda, E., Marinelli, F., Marcone, G., Old and new glycopeptide antibiotics: action and resistance. Antibiotics 3 (2014), 572–594, 10.3390/antibiotics3040572.
    • (2014) Antibiotics , vol.3 , pp. 572-594
    • Binda, E.1    Marinelli, F.2    Marcone, G.3
  • 24
    • 84901315042 scopus 로고    scopus 로고
    • Pilot study of seasonal occurrence and distribution of antibiotics and drug resistant bacteria in wastewater treatment plants in Slovakia
    • Birošová, L., Mackulak, T., Bodík, I., et al. Pilot study of seasonal occurrence and distribution of antibiotics and drug resistant bacteria in wastewater treatment plants in Slovakia. Sci. Total Environ. 490 (2014), 440–444, 10.1016/j.scitotenv.2014.05.030.
    • (2014) Sci. Total Environ. , vol.490 , pp. 440-444
    • Birošová, L.1    Mackulak, T.2    Bodík, I.3
  • 25
    • 3843063283 scopus 로고    scopus 로고
    • Fast and robust simultaneous determination of three veterinary antibiotics in groundwater and surface water using a tandem solid-phase extraction with high-performance liquid chromatography–UV detection
    • Blackwell, P.A., Lützhøft, H.C.H., Ma, H.P., et al. Fast and robust simultaneous determination of three veterinary antibiotics in groundwater and surface water using a tandem solid-phase extraction with high-performance liquid chromatography–UV detection. J. Chromatogr. A 1045 (2004), 111–117, 10.1016/j.chroma.2004.05.063.
    • (2004) J. Chromatogr. A , vol.1045 , pp. 111-117
    • Blackwell, P.A.1    Lützhøft, H.C.H.2    Ma, H.P.3
  • 26
    • 61849120257 scopus 로고    scopus 로고
    • Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils
    • Blackwell, P.A., Kay, P., Ashauer, R., Boxall, A.B.A., Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. Chemosphere 75 (2009), 13–19, 10.1016/j.chemosphere.2008.11.070.
    • (2009) Chemosphere , vol.75 , pp. 13-19
    • Blackwell, P.A.1    Kay, P.2    Ashauer, R.3    Boxall, A.B.A.4
  • 27
    • 84944231389 scopus 로고    scopus 로고
    • Biotransformation of pharmaceuticals in surface water and during waste water treatment: identification and occurrence of transformation products
    • Boix, C., Ibáñez, M., Sancho, J.V., et al. Biotransformation of pharmaceuticals in surface water and during waste water treatment: identification and occurrence of transformation products. J. Hazard. Mater. 302 (2015), 175–187, 10.1016/j.jhazmat.2015.09.053.
    • (2015) J. Hazard. Mater. , vol.302 , pp. 175-187
    • Boix, C.1    Ibáñez, M.2    Sancho, J.V.3
  • 28
    • 84908424361 scopus 로고    scopus 로고
    • Fast determination of 40 drugs in water using large volume direct injection liquid chromatography–tandem mass spectrometry
    • Boix, C., Ibáñez, M., Sancho, J.V., et al. Fast determination of 40 drugs in water using large volume direct injection liquid chromatography–tandem mass spectrometry. Talanta 131 (2015), 719–727, 10.1016/j.talanta.2014.08.005.
    • (2015) Talanta , vol.131 , pp. 719-727
    • Boix, C.1    Ibáñez, M.2    Sancho, J.V.3
  • 29
    • 84875524975 scopus 로고    scopus 로고
    • Validation and uncertainty estimation of a multiresidue method for pharmaceuticals in surface and treated waters by liquid chromatography–tandem mass spectrometry
    • Boleda, M.R., Galceran, M.T., Ventura, F., Validation and uncertainty estimation of a multiresidue method for pharmaceuticals in surface and treated waters by liquid chromatography–tandem mass spectrometry. J. Chromatogr. A 1286 (2013), 146–158, 10.1016/j.chroma.2013.02.077.
    • (2013) J. Chromatogr. A , vol.1286 , pp. 146-158
    • Boleda, M.R.1    Galceran, M.T.2    Ventura, F.3
  • 30
    • 70349759361 scopus 로고    scopus 로고
    • An overview of sample preparation procedures for LC–MS multiclass antibiotic determination in environmental and food samples
    • Bondi, M.C.M., Marazuela, M.D., Herranz, S., Rodriguez, E., An overview of sample preparation procedures for LC–MS multiclass antibiotic determination in environmental and food samples. Anal. Bioanal. Chem. 395 (2009), 921–946.
    • (2009) Anal. Bioanal. Chem. , vol.395 , pp. 921-946
    • Bondi, M.C.M.1    Marazuela, M.D.2    Herranz, S.3    Rodriguez, E.4
  • 31
    • 84881028889 scopus 로고    scopus 로고
    • A new approach for the estimation of expanded uncertainty of results of an analytical method developed for determining antibiotics in seawater using solid-phase extraction disks and liquid chromatography coupled with tandem mass spectrometry technique
    • Borecka, M., Bielińska, A.B., Siedlewicz, G., et al. A new approach for the estimation of expanded uncertainty of results of an analytical method developed for determining antibiotics in seawater using solid-phase extraction disks and liquid chromatography coupled with tandem mass spectrometry technique. J. Chromatogr. A 1304 (2013), 138–146, 10.1016/j.chroma.2013.07.018.
    • (2013) J. Chromatogr. A , vol.1304 , pp. 138-146
    • Borecka, M.1    Bielińska, A.B.2    Siedlewicz, G.3
  • 32
    • 84923368675 scopus 로고    scopus 로고
    • Detection and quantification of residues and metabolites of medicinal products in environmental compartments, food commodities and workplaces: a review
    • Bottoni, P., Caroli, S., Detection and quantification of residues and metabolites of medicinal products in environmental compartments, food commodities and workplaces: a review. J. Pharm. Biomed. Anal. 106 (2014), 3–24, 10.1016/j.jpba.2014.12.019.
    • (2014) J. Pharm. Biomed. Anal. , vol.106 , pp. 3-24
    • Bottoni, P.1    Caroli, S.2
  • 33
    • 0141924469 scopus 로고    scopus 로고
    • Pharmaceutical antibiotic compounds in soils: A review
    • Bruhn, S.T., Pharmaceutical antibiotic compounds in soils: A review. J. Plant Nutr. Soil Sci. 166 (2003), 145–167, 10.1002/jpln.200390023.
    • (2003) J. Plant Nutr. Soil Sci. , vol.166 , pp. 145-167
    • Bruhn, S.T.1
  • 34
    • 84883794092 scopus 로고    scopus 로고
    • Pharmaceuticals and personal care products in the aquatic environment in China: a review
    • Bu, Q., Wang, B., Huang, J., et al. Pharmaceuticals and personal care products in the aquatic environment in China: a review. J. Hazard. Mater. 262 (2013), 189–211, 10.1016/j.jhazmat.2013.08.040.
    • (2013) J. Hazard. Mater. , vol.262 , pp. 189-211
    • Bu, Q.1    Wang, B.2    Huang, J.3
  • 35
    • 34249288312 scopus 로고    scopus 로고
    • Novel analytical procedures for screening of drug residues in water, waste water, sediment and sludge
    • Buchberger, W.W., Novel analytical procedures for screening of drug residues in water, waste water, sediment and sludge. Anal. Chim. Acta 593 (2007), 129–139, 10.1016/j.aca.2007.05.006.
    • (2007) Anal. Chim. Acta , vol.593 , pp. 129-139
    • Buchberger, W.W.1
  • 36
    • 78650791934 scopus 로고    scopus 로고
    • Current approaches to trace analysis of pharmaceuticals and personal care products in the environment
    • Buchberger, W.W., Current approaches to trace analysis of pharmaceuticals and personal care products in the environment. J. Chromatogr. A 1218 (2011), 603–618, 10.1016/j.chroma.2010.10.040.
    • (2011) J. Chromatogr. A , vol.1218 , pp. 603-618
    • Buchberger, W.W.1
  • 37
    • 84867720022 scopus 로고    scopus 로고
    • Monitoring the occurrence of emerging contaminants in treated wastewater and groundwater between 2008 and 2010. The Baix Llobregat (Barcelona, Spain)
    • Cabeza, Y., Candela, L., Ronen, D., Teijon, G., Monitoring the occurrence of emerging contaminants in treated wastewater and groundwater between 2008 and 2010. The Baix Llobregat (Barcelona, Spain). J. Hazard. Mater. 239-240 (2012), 32–39, 10.1016/j.jhazmat.2012.07.032.
    • (2012) J. Hazard. Mater. , vol.239-240 , pp. 32-39
    • Cabeza, Y.1    Candela, L.2    Ronen, D.3    Teijon, G.4
  • 38
    • 25844491008 scopus 로고    scopus 로고
    • A multiresidue analytical method using solid-phase extraction and high-pressure liquid chromatography tandem mass spectrometry to measure pharmaceuticals of different therapeutic classes in urban wastewaters
    • Castiglioni, S., Bagnati, R., Calamari, D., et al. A multiresidue analytical method using solid-phase extraction and high-pressure liquid chromatography tandem mass spectrometry to measure pharmaceuticals of different therapeutic classes in urban wastewaters. J. Chromatogr. A 1092 (2005), 206–215, 10.1016/j.chroma.2005.07.012.
    • (2005) J. Chromatogr. A , vol.1092 , pp. 206-215
    • Castiglioni, S.1    Bagnati, R.2    Calamari, D.3
  • 39
    • 84884597711 scopus 로고    scopus 로고
    • Antibiotic resistance threats in the United States
    • (Georgia)
    • CDC, Antibiotic resistance threats in the United States. 2013 (Georgia).
    • (2013)
    • CDC1
  • 40
    • 84989348477 scopus 로고    scopus 로고
    • Transatlantic task force on antimicrobial resistance
    • (Accessed 22 Oct 2015)
    • CDC, Transatlantic task force on antimicrobial resistance. http://www.cdc.gov/drugresistance/tatfar/press_releases.html, 2015 (Accessed 22 Oct 2015).
    • (2015)
    • CDC1
  • 41
    • 84904328214 scopus 로고    scopus 로고
    • Ultra-preconcentration and determination of selected pharmaceutical and personal care products in different water matrices by solid-phase extraction combined with dispersive liquid–liquid microextraction prior to ultra high pressure liquid chromatography
    • Celano, R., Piccinelli, A.L., Campone, L., Rastrelli, L., Ultra-preconcentration and determination of selected pharmaceutical and personal care products in different water matrices by solid-phase extraction combined with dispersive liquid–liquid microextraction prior to ultra high pressure liquid chromatography. J. Chromatogr. A 1355 (2014), 26–35, 10.1016/j.chroma.2014.06.009.
    • (2014) J. Chromatogr. A , vol.1355 , pp. 26-35
    • Celano, R.1    Piccinelli, A.L.2    Campone, L.3    Rastrelli, L.4
  • 42
    • 84937250978 scopus 로고    scopus 로고
    • Preliminary survey of pharmaceutical residues in some important Romanian rivers
    • Chițescu, C.L., Nicolau, A.I., Preliminary survey of pharmaceutical residues in some important Romanian rivers. Toxicol. Environ. Chem. 96 (2014), 1333–1345, 10.1080/02772248.2015.1005092.
    • (2014) Toxicol. Environ. Chem. , vol.96 , pp. 1333-1345
    • Chițescu, C.L.1    Nicolau, A.I.2
  • 43
    • 84863751070 scopus 로고    scopus 로고
    • Accurate mass screening of pharmaceuticals and fungicides in water by U-HPLC-Exactive Orbitrap MS
    • Chitescu, C.L., Oosterink, E., Jong, J., Stolker, A.A.M.L., Accurate mass screening of pharmaceuticals and fungicides in water by U-HPLC-Exactive Orbitrap MS. Anal. Bioanal. Chem. 403 (2012), 2997–3011, 10.1007/s00216-012-5888-8.
    • (2012) Anal. Bioanal. Chem. , vol.403 , pp. 2997-3011
    • Chitescu, C.L.1    Oosterink, E.2    Jong, J.3    Stolker, A.A.M.L.4
  • 44
    • 84935011486 scopus 로고    scopus 로고
    • High sensitive multiresidue analysis of pharmaceuticals and antifungals in surface water using U-HPLC-Q-Exactive Orbitrap HRMS. Application to the Danube river basin on the Romanian territory
    • Chitescu, C.L., Kaklamanos, G., Nicolau, A.I., Stolker, A.A.M.L., High sensitive multiresidue analysis of pharmaceuticals and antifungals in surface water using U-HPLC-Q-Exactive Orbitrap HRMS. Application to the Danube river basin on the Romanian territory. Sci. Total Environ. 532 (2015), 501–511, 10.1016/j.scitotenv.2015.06.010.
    • (2015) Sci. Total Environ. , vol.532 , pp. 501-511
    • Chitescu, C.L.1    Kaklamanos, G.2    Nicolau, A.I.3    Stolker, A.A.M.L.4
  • 45
    • 0041823405 scopus 로고    scopus 로고
    • Determination of antibiotic residues in manure, soil, and surface waters
    • Christian, T., Schneider, R.J., Färber, H.A., et al. Determination of antibiotic residues in manure, soil, and surface waters. Acta Hydrochim. Hydrobiol. 31 (2003), 36–44, 10.1002/aheh.200390014.
    • (2003) Acta Hydrochim. Hydrobiol. , vol.31 , pp. 36-44
    • Christian, T.1    Schneider, R.J.2    Färber, H.A.3
  • 46
    • 27744498927 scopus 로고    scopus 로고
    • Removal of selected pharmaceuticals, fragrances and endocrine disrupting compounds in a membrane bioreactor and conventional wastewater treatment plants
    • Clara, M., Strenn, B., Gans, O., et al. Removal of selected pharmaceuticals, fragrances and endocrine disrupting compounds in a membrane bioreactor and conventional wastewater treatment plants. Water Res. 39 (2005), 4797–4807, 10.1016/j.watres.2005.09.015.
    • (2005) Water Res. , vol.39 , pp. 4797-4807
    • Clara, M.1    Strenn, B.2    Gans, O.3
  • 47
    • 84904883483 scopus 로고    scopus 로고
    • Incidence of anticancer drugs in an aquatic urban system: from hospital effluents through urban wastewater to natural environment
    • Climent, L.F., Mozaz, S.R., Barceló, D., Incidence of anticancer drugs in an aquatic urban system: from hospital effluents through urban wastewater to natural environment. Environ. Pollut. 193 (2014), 216–223, 10.1016/j.envpol.2014.07.002.
    • (2014) Environ. Pollut. , vol.193 , pp. 216-223
    • Climent, L.F.1    Mozaz, S.R.2    Barceló, D.3
  • 48
    • 79953710021 scopus 로고    scopus 로고
    • Novel classes of antibiotics or more of the same?
    • Coates, A.R.M., Halls, G., Hu, Y., Novel classes of antibiotics or more of the same?. Br. J. Pharmacol. 163 (2011), 184–194, 10.1111/j.1476-5381.2011.01250.x.
    • (2011) Br. J. Pharmacol. , vol.163 , pp. 184-194
    • Coates, A.R.M.1    Halls, G.2    Hu, Y.3
  • 49
    • 84888619732 scopus 로고    scopus 로고
    • Pharmaceuticals occurrence in a WWTP with significant industrial contribution and its input into the river system
    • Collado, N., Mozaz, S.R., Gros, M., et al. Pharmaceuticals occurrence in a WWTP with significant industrial contribution and its input into the river system. Environ. Pollut. 185 (2014), 202–212, 10.1016/j.envpol.2013.10.040.
    • (2014) Environ. Pollut. , vol.185 , pp. 202-212
    • Collado, N.1    Mozaz, S.R.2    Gros, M.3
  • 50
    • 84877128702 scopus 로고    scopus 로고
    • Temporal dynamics of antibiotics in wastewater treatment plant influent
    • Coutu, S., Wyrsch, V., Wynn, H.K., et al. Temporal dynamics of antibiotics in wastewater treatment plant influent. Sci. Total Environ. 458-460 (2013), 20–26, 10.1016/j.scitotenv.2013.04.017.
    • (2013) Sci. Total Environ. , vol.458-460 , pp. 20-26
    • Coutu, S.1    Wyrsch, V.2    Wynn, H.K.3
  • 51
    • 84893147032 scopus 로고    scopus 로고
    • Taking action to preserve the miracle of antibiotics
    • Cruickshank, M., Duguid, M., Gotterson, F., Carter, D., Taking action to preserve the miracle of antibiotics. Aust. Vet. J. 92 (2014), 3–7, 10.1111/avj.12144.
    • (2014) Aust. Vet. J. , vol.92 , pp. 3-7
    • Cruickshank, M.1    Duguid, M.2    Gotterson, F.3    Carter, D.4
  • 52
    • 43449136442 scopus 로고    scopus 로고
    • Highly sensitive simultaneous determination of sulfonamide antibiotics and one metabolite in environmental waters by liquid chromatography–quadrupole linear ion trap–mass spectrometry
    • Cruz, M.S.D., Galán, M.J.G., Barceló, D., Highly sensitive simultaneous determination of sulfonamide antibiotics and one metabolite in environmental waters by liquid chromatography–quadrupole linear ion trap–mass spectrometry. J. Chromatogr. A 1193 (2008), 50–59, 10.1016/j.chroma.2008.03.029.
    • (2008) J. Chromatogr. A , vol.1193 , pp. 50-59
    • Cruz, M.S.D.1    Galán, M.J.G.2    Barceló, D.3
  • 53
  • 54
    • 77957980707 scopus 로고    scopus 로고
    • Origins and evolution of antibiotic resistance
    • Davies, J., Davies, D., Origins and evolution of antibiotic resistance. Microbiol. Mol. Biol. Rev. 74 (2010), 417–433, 10.1128/MMBR.00016-10.
    • (2010) Microbiol. Mol. Biol. Rev. , vol.74 , pp. 417-433
    • Davies, J.1    Davies, D.2
  • 56
    • 84870653348 scopus 로고    scopus 로고
    • Ultra-trace analysis of hormones, pharmaceutical substances, alkylphenols and phthalates in two French natural mineral waters
    • Dévier, M.H., Le Menach, K., Viglino, L., et al. Ultra-trace analysis of hormones, pharmaceutical substances, alkylphenols and phthalates in two French natural mineral waters. Sci. Total Environ. 443 (2013), 621–632, 10.1016/j.scitotenv.2012.10.015.
    • (2013) Sci. Total Environ. , vol.443 , pp. 621-632
    • Dévier, M.H.1    Le Menach, K.2    Viglino, L.3
  • 57
    • 34250005555 scopus 로고    scopus 로고
    • Determination of antimicrobial residues and metabolites in the aquatic environment by liquid chromatography tandem mass spectrometry
    • Díaz-Cruz, M.S., Barceló, D., Determination of antimicrobial residues and metabolites in the aquatic environment by liquid chromatography tandem mass spectrometry. Anal. Bioanal. Chem. 386 (2006), 973–985, 10.1007/s00216-006-0444-z.
    • (2006) Anal. Bioanal. Chem. , vol.386 , pp. 973-985
    • Díaz-Cruz, M.S.1    Barceló, D.2
  • 58
    • 79961128242 scopus 로고    scopus 로고
    • Measurement of trace levels of antibiotics in river water using on-line enrichment and triple–quadrupole LC–MS/MS
    • Dinh, Q.T., Alliot, F., Guigon, E.M., et al. Measurement of trace levels of antibiotics in river water using on-line enrichment and triple–quadrupole LC–MS/MS. Talanta 85 (2011), 1238–1245, 10.1016/j.talanta.2011.05.013.
    • (2011) Talanta , vol.85 , pp. 1238-1245
    • Dinh, Q.T.1    Alliot, F.2    Guigon, E.M.3
  • 59
    • 81155125070 scopus 로고    scopus 로고
    • Toxicity of the fluoroquinolone antibiotics enrofloxacin and ciprofloxacin to photoautotrophic aquatic organisms
    • Ebert, I., Bachmann, J., Kühnen, U., et al. Toxicity of the fluoroquinolone antibiotics enrofloxacin and ciprofloxacin to photoautotrophic aquatic organisms. Environ. Toxicol. Chem. 30 (2011), 2786–2792, 10.1002/etc.678.
    • (2011) Environ. Toxicol. Chem. , vol.30 , pp. 2786-2792
    • Ebert, I.1    Bachmann, J.2    Kühnen, U.3
  • 60
    • 84989326234 scopus 로고
    • Council Regulation (EEC) No 2377/90 of 26 June 1990 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin. Off. J. Eur. Communities L224:1–8. \n
    • EC (1990) Council Regulation (EEC) No 2377/90 of 26 June 1990 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin. Off. J. Eur. Communities L224:1–8. \nhttp://ec.europa.eu/health/files/eudralex/vol-5/reg_1990_2377/reg_1990_2377_en.pdf.
    • (1990)
  • 61
    • 80054022420 scopus 로고    scopus 로고
    • Commission Directive 98/15/EC of 27 February 1998 amending Council Directive 91/271/EEC with respect to certain requirements established in Annex I thereof
    • EC, Commission Directive 98/15/EC of 27 February 1998 amending Council Directive 91/271/EEC with respect to certain requirements established in Annex I thereof. Off J. Eur. Union L 67 (1998), 29–30.
    • (1998) Off J. Eur. Union L , vol.67 , pp. 29-30
    • EC1
  • 62
    • 84989799882 scopus 로고    scopus 로고
    • Directive 2000/60/EC of the European Parliament and of the Council of 23 October 2000 establishing a framework for Community action in the field of water policy
    • EC, Directive 2000/60/EC of the European Parliament and of the Council of 23 October 2000 establishing a framework for Community action in the field of water policy. Off J. Eur. Parliam. L 327 (2000), 1–82.
    • (2000) Off J. Eur. Parliam. L , vol.327 , pp. 1-82
    • EC1
  • 63
    • 0043264411 scopus 로고    scopus 로고
    • Decision No 2455/2001/EC of the European Parliament and of the Council of 20 November 2001 establishing the list of priority substances in the field of water policy and amending Directive 2000/60/EC
    • EC, Decision No 2455/2001/EC of the European Parliament and of the Council of 20 November 2001 establishing the list of priority substances in the field of water policy and amending Directive 2000/60/EC. Off J. Eur. Commun. L 331 (2001), 1–5.
    • (2001) Off J. Eur. Commun. L , vol.331 , pp. 1-5
    • EC1
  • 64
    • 12844283422 scopus 로고    scopus 로고
    • Regulation (EC) No. 1831/2003 of the European Parliament and of the Council of 22 September 2003 on additives for use in animal nutrition
    • EC, Regulation (EC) No. 1831/2003 of the European Parliament and of the Council of 22 September 2003 on additives for use in animal nutrition. Off. J. Eur. Union L268 (2003), 29–42.
    • (2003) Off. J. Eur. Union , vol.L268 , pp. 29-42
    • EC1
  • 65
    • 84989312460 scopus 로고    scopus 로고
    • Council and parliament prohibit antibiotics as growth promoters: Commissioner Byrne welcomes adoption of Regulation on feed additives
    • (. Accessed 16 Nov 2015)
    • EC, Council and parliament prohibit antibiotics as growth promoters: Commissioner Byrne welcomes adoption of Regulation on feed additives. IP/03/1058, 2003 (http://europa.eu/rapid/press-release_IP-03-1058_en.htm?locale=en. Accessed 16 Nov 2015).
    • (2003) IP/03/1058
    • EC1
  • 66
    • 35448954076 scopus 로고    scopus 로고
    • Directive 2006/118/EC of the European parliamand and of the council on the protection of groundwater against pollution and deterioration
    • EC, Directive 2006/118/EC of the European parliamand and of the council on the protection of groundwater against pollution and deterioration. Off J. Eur. Union L 372 (2006), 19–31.
    • (2006) Off J. Eur. Union L , vol.372 , pp. 19-31
    • EC1
  • 67
    • 63149099986 scopus 로고    scopus 로고
    • Directive 2008/105/EC of the European Parliament and of the Council of 16 December 2008 on environmental quality standards in the field of water policy, amending and subsequently repealing Council Directives 82/176/EEC, 83/513/EEC, 84/156/EEC, 84/491/EEC
    • EC, Directive 2008/105/EC of the European Parliament and of the Council of 16 December 2008 on environmental quality standards in the field of water policy, amending and subsequently repealing Council Directives 82/176/EEC, 83/513/EEC, 84/156/EEC, 84/491/EEC. Off J. Eur. Union L 348 (2008), 84–97.
    • (2008) Off J. Eur. Union L , vol.348 , pp. 84-97
    • EC1
  • 68
    • 84865362301 scopus 로고    scopus 로고
    • Communication from the Commission to the European Parliament and the Council: Action plan against the rising threats from Antimicrobial Resistance
    • (Brussels)
    • EC, Communication from the Commission to the European Parliament and the Council: Action plan against the rising threats from Antimicrobial Resistance. 2011 (Brussels).
    • (2011)
    • EC1
  • 69
    • 84887758035 scopus 로고    scopus 로고
    • Directive 2013/39/EU of the European Parliament and of the Council of 12 August 2013 amending Directives 2000/60/EC and 2008/105/EC as regards priority substances in the field of water policy
    • EC, Directive 2013/39/EU of the European Parliament and of the Council of 12 August 2013 amending Directives 2000/60/EC and 2008/105/EC as regards priority substances in the field of water policy. Off J. Eur. Union L 226 (2013), 1–17.
    • (2013) Off J. Eur. Union L , vol.226 , pp. 1-17
    • EC1
  • 70
    • 84989308427 scopus 로고    scopus 로고
    • Commission Adopts Proposals To Improve Animal And Human Health
    • (. Accessed 16 Nov 2015)
    • EC, Commission Adopts Proposals To Improve Animal And Human Health. IP/14/987, 2014 (http://europa.eu/rapid/press-release_IP-14-987_en.htm. Accessed 16 Nov 2015).
    • (2014) IP/14/987
    • EC1
  • 71
    • 84937958432 scopus 로고    scopus 로고
    • Decision (EU) 2015/495 of 20 March 2015 establishing a watch list of substances for Union-wide monitoring in the field of water policy pursuant to Directive 2008/105/EC of the European Parliament and of the Council
    • EC, Decision (EU) 2015/495 of 20 March 2015 establishing a watch list of substances for Union-wide monitoring in the field of water policy pursuant to Directive 2008/105/EC of the European Parliament and of the Council. Off J. Eur. Parliam. L 78 (2015), 40–42.
    • (2015) Off J. Eur. Parliam. L , vol.78 , pp. 40-42
    • EC1
  • 72
    • 84937893066 scopus 로고    scopus 로고
    • Action plan against antimicrobial resistance
    • (Accessed 7 Sep 2015)
    • EC, Action plan against antimicrobial resistance. http://ec.europa.eu/health/antimicrobial_resistance/policy/index_en.htm, 2015 (Accessed 7 Sep 2015).
    • (2015)
    • EC1
  • 73
    • 84989327003 scopus 로고    scopus 로고
    • Antimicrobial resistance projects
    • (Accessed 7 Sep 2015)
    • EC, Antimicrobial resistance projects. http://ec.europa.eu/health/antimicrobial_resistance/projects/index_en.htm, 2015 (Accessed 7 Sep 2015).
    • (2015)
    • EC1
  • 74
    • 84881601561 scopus 로고    scopus 로고
    • Surveillance Of Antimicrobial Consumption In Europe: 2010
    • (Stockholm)
    • ECDC, Surveillance Of Antimicrobial Consumption In Europe: 2010. 2013 (Stockholm).
    • (2013)
    • ECDC1
  • 75
    • 84881601561 scopus 로고    scopus 로고
    • Surveillance Of Antimicrobial Consumption In Europe: 2012
    • (Stockholm)
    • ECDC, Surveillance Of Antimicrobial Consumption In Europe: 2012. 2014 (Stockholm).
    • (2014)
    • ECDC1
  • 76
    • 84881601561 scopus 로고    scopus 로고
    • Surveillance Of Antimicrobial Consumption In Europe: 2011
    • (Stockholm)
    • ECDC, Surveillance Of Antimicrobial Consumption In Europe: 2011. 2014 (Stockholm).
    • (2014)
    • ECDC1
  • 77
    • 84901809320 scopus 로고    scopus 로고
    • Antimicrobial resistance
    • (Accessed 7 Sep 2015)
    • ECDC, Antimicrobial resistance. http://ecdc.europa.eu/en/activities/surveillance/ESAC-Net/Pages/index.aspx, 2015 (Accessed 7 Sep 2015).
    • (2015)
    • ECDC1
  • 78
    • 84901809320 scopus 로고    scopus 로고
    • Antimicrobial resistance
    • (Accessed 16 Nov 2015)
    • ECDC, Antimicrobial resistance. http://ecdc.europa.eu/en/healthtopics/antimicrobial_resistance/Pages/index.aspx, 2015 (Accessed 16 Nov 2015).
    • (2015)
    • ECDC1
  • 79
    • 84989294568 scopus 로고    scopus 로고
    • Antimicrobial consumption interactive database (ESAC-Net)
    • (Accessed 16 Nov 2015)
    • ECDC, Antimicrobial consumption interactive database (ESAC-Net). http://ecdc.europa.eu/en/healthtopics/antimicrobial_resistance/esac-net-database/Pages/database.aspx, 2015 (Accessed 16 Nov 2015).
    • (2015)
    • ECDC1
  • 80
    • 77951132271 scopus 로고    scopus 로고
    • The Bacterial Challenge: Time to React
    • (Stockholm)
    • ECDC, EMA, The Bacterial Challenge: Time to React. 2009 (Stockholm).
    • (2009)
    • ECDC, EMA,1
  • 81
    • 0003176801 scopus 로고
    • Council Directive of 21 May 1991 concerning urban waste water treatment (91/271/EEC)
    • EEC Council, Council Directive of 21 May 1991 concerning urban waste water treatment (91/271/EEC). Off J. Eur. Commun. L 135 (1991), 40–52.
    • (1991) Off J. Eur. Commun. L , vol.135 , pp. 40-52
    • EEC Council1
  • 82
    • 84901809320 scopus 로고    scopus 로고
    • Antimicrobial Resistance
    • (Accessed 7 Sep 2015)
    • EFSA, Antimicrobial Resistance. http://www.efsa.europa.eu/en/topics/topic/amr, 2015 (Accessed 7 Sep 2015).
    • (2015)
    • EFSA1
  • 83
    • 84989297375 scopus 로고    scopus 로고
    • Trends In The Sales Of Veterinary Antimicrobial Agents In Nine European Countries: Reporting Period 2005–2009
    • (London)
    • EMA, Trends In The Sales Of Veterinary Antimicrobial Agents In Nine European Countries: Reporting Period 2005–2009. 2011 (London).
    • (2011)
    • EMA1
  • 84
    • 84892536163 scopus 로고    scopus 로고
    • Sales of Veterinary Antimicrobial Agents in 19 EU/EEA Countries in 2010: Second ESVAC Report
    • (London)
    • EMA, Sales of Veterinary Antimicrobial Agents in 19 EU/EEA Countries in 2010: Second ESVAC Report. 2012 (London).
    • (2012)
    • EMA1
  • 85
    • 84892536163 scopus 로고    scopus 로고
    • Sales of Veterinary Antimicrobial agEnts in 25 EU/EEA Countries in 2011: Third ESVAC Report
    • (London)
    • EMA, Sales of Veterinary Antimicrobial agEnts in 25 EU/EEA Countries in 2011: Third ESVAC Report. 2013 (London).
    • (2013)
    • EMA1
  • 86
    • 84908498510 scopus 로고    scopus 로고
    • Revised ESVAC Reflection Paper On Collecting Data On Consumption Of Antimicrobial Agents Per Animal Species, On Technical Units Of Measurement And Indicators For Reporting Consumption Of Antimicrobial Agents In Animals
    • (London)
    • EMA, Revised ESVAC Reflection Paper On Collecting Data On Consumption Of Antimicrobial Agents Per Animal Species, On Technical Units Of Measurement And Indicators For Reporting Consumption Of Antimicrobial Agents In Animals. 2013 (London).
    • (2013)
    • EMA1
  • 87
    • 84892536163 scopus 로고    scopus 로고
    • Sales of Veterinary Antimicrobial Agents in 26 EU/EEA coUntries in 2012: Fourth ESVAC Report
    • (London)
    • EMA, Sales of Veterinary Antimicrobial Agents in 26 EU/EEA coUntries in 2012: Fourth ESVAC Report. 2014 (London).
    • (2014)
    • EMA1
  • 88
    • 84989294814 scopus 로고    scopus 로고
    • European Surveillance of Veterinary Antimicrobial Consumption (ESVAC)
    • (Accessed 7 Sep 2015)
    • EMA, European Surveillance of Veterinary Antimicrobial Consumption (ESVAC). http://www.ema.europa.eu/ema/index.jsp?curl=pages/regulation/document_listing/document_listing_000302.jsp&mid=WC0b01ac0580153a00, 2015 (Accessed 7 Sep 2015).
    • (2015)
    • EMA1
  • 89
    • 84892536163 scopus 로고    scopus 로고
    • Sales of Veterinary Antimicrobial Agents in 25 EU/EEA Countries in 2013: Fifth ESVAC Report
    • (London)
    • EMA, Sales of Veterinary Antimicrobial Agents in 25 EU/EEA Countries in 2013: Fifth ESVAC Report. 2015 (London).
    • (2015)
    • EMA1
  • 90
    • 85030418100 scopus 로고    scopus 로고
    • Principles On Assignment Of Defined Daily Dose For Animals (DDDvet) And Defined Course Dose For Animals (DCDvet)
    • (London)
    • EMA, Principles On Assignment Of Defined Daily Dose For Animals (DDDvet) And Defined Course Dose For Animals (DCDvet). 2015 (London).
    • (2015)
    • EMA1
  • 91
    • 84909953526 scopus 로고    scopus 로고
    • Occurrence and removal of transformation products of PPCPs and illicit drugs in wastewaters: a review
    • Evgenidou, E.N., Konstantinou, I.K., Lambropoulou, D.A., Occurrence and removal of transformation products of PPCPs and illicit drugs in wastewaters: a review. Sci. Total Environ. 505 (2015), 905–926, 10.1016/j.scitotenv.2014.10.021.
    • (2015) Sci. Total Environ. , vol.505 , pp. 905-926
    • Evgenidou, E.N.1    Konstantinou, I.K.2    Lambropoulou, D.A.3
  • 92
    • 56449083885 scopus 로고    scopus 로고
    • Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment
    • Farré, M., Pérez, S., Kantiani, L., Barceló, D., Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment. Trends Anal. Chem. 27 (2008), 991–1007, 10.1016/j.trac.2008.09.010.
    • (2008) Trends Anal. Chem. , vol.27 , pp. 991-1007
    • Farré, M.1    Pérez, S.2    Kantiani, L.3    Barceló, D.4
  • 93
    • 84866325397 scopus 로고    scopus 로고
    • Achievements and future trends in the analysis of emerging organic contaminants in environmental samples by mass spectrometry and bioanalytical techniques
    • Farré, M., Kantiani, L., Petrovic, M., et al. Achievements and future trends in the analysis of emerging organic contaminants in environmental samples by mass spectrometry and bioanalytical techniques. J. Chromatogr. A 1259 (2012), 86–99, 10.1016/j.chroma.2012.07.024.
    • (2012) J. Chromatogr. A , vol.1259 , pp. 86-99
    • Farré, M.1    Kantiani, L.2    Petrovic, M.3
  • 94
    • 34250001661 scopus 로고    scopus 로고
    • Analytical methods for tracing pharmaceutical residues in water and wastewater
    • Fatta, D., Achilleos, A., Nikolaou, A., Meriç, S., Analytical methods for tracing pharmaceutical residues in water and wastewater. Trends Anal. Chem. 26 (2007), 515–533, 10.1016/j.trac.2007.02.001.
    • (2007) Trends Anal. Chem. , vol.26 , pp. 515-533
    • Fatta, D.1    Achilleos, A.2    Nikolaou, A.3    Meriç, S.4
  • 95
    • 57649210967 scopus 로고    scopus 로고
    • Occurrence and distribution of selected antibiotics in a small Mediterranean stream (Arc River, Southern France)
    • Felizzola, J.F., Chiron, S., Occurrence and distribution of selected antibiotics in a small Mediterranean stream (Arc River, Southern France). J. Hydrol. 364 (2009), 50–57, 10.1016/j.jhydrol.2008.10.006.
    • (2009) J. Hydrol. , vol.364 , pp. 50-57
    • Felizzola, J.F.1    Chiron, S.2
  • 96
    • 84858446677 scopus 로고    scopus 로고
    • New developments in the trace analysis of organic water pollutants
    • Fischer, K., Fries, E., Körner, W., et al. New developments in the trace analysis of organic water pollutants. Appl. Microbiol. Botechnol. 94 (2012), 11–28, 10.1007/s00253-012-3929-z.
    • (2012) Appl. Microbiol. Botechnol. , vol.94 , pp. 11-28
    • Fischer, K.1    Fries, E.2    Körner, W.3
  • 97
    • 0026563389 scopus 로고
    • The quinolones: An overview of their pharmacology
    • Fitton, A., The quinolones: An overview of their pharmacology. Clin. Pharmacokinet. 22:Suppl. 1 (1992), 1–11.
    • (1992) Clin. Pharmacokinet. , vol.22 , pp. 1-11
    • Fitton, A.1
  • 98
    • 48649092025 scopus 로고    scopus 로고
    • A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States-II) untreated drinking water sources
    • Focazio, M.J., Kolpin, D.W., Barnes, K.K., et al. A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States-II) untreated drinking water sources. Sci. Total Environ. 402 (2008), 201–216, 10.1016/j.scitotenv.2008.02.021.
    • (2008) Sci. Total Environ. , vol.402 , pp. 201-216
    • Focazio, M.J.1    Kolpin, D.W.2    Barnes, K.K.3
  • 99
    • 78649712445 scopus 로고    scopus 로고
    • The continuing crisis in antibiotic resistance
    • French, G.L., The continuing crisis in antibiotic resistance. Int. J. Antimicrob. Agents 36 (2010), S3–S7, 10.1016/S0924-8579(10)70003-0.
    • (2010) Int. J. Antimicrob. Agents , vol.36 , pp. S3-S7
    • French, G.L.1
  • 100
    • 84930622465 scopus 로고    scopus 로고
    • Occurrence of pharmaceuticals in a water supply system and related human health risk assessment
    • Gaffney, V.J., Almeida, C.M.M., Rodrigues, A., et al. Occurrence of pharmaceuticals in a water supply system and related human health risk assessment. Water Res. 72 (2015), 199–208, 10.1016/j.watres.2014.10.027.
    • (2015) Water Res. , vol.72 , pp. 199-208
    • Gaffney, V.J.1    Almeida, C.M.M.2    Rodrigues, A.3
  • 101
    • 56449112876 scopus 로고    scopus 로고
    • Identification and determination of metabolites and degradation products of sulfonamide antibiotics
    • Galán, M.J.G., Cruz, M.S.D., Barceló, D., Identification and determination of metabolites and degradation products of sulfonamide antibiotics. Trends Anal. Chem. 27 (2008), 1008–1022, 10.1016/j.trac.2008.10.001.
    • (2008) Trends Anal. Chem. , vol.27 , pp. 1008-1022
    • Galán, M.J.G.1    Cruz, M.S.D.2    Barceló, D.3
  • 102
    • 77249156714 scopus 로고    scopus 로고
    • Determination of 19 sulfonamides in environmental water samples by automated on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry (SPE-LC-MS/MS)
    • Galán, M.J.G., Cruz, M.S.D., Barceló, D., Determination of 19 sulfonamides in environmental water samples by automated on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry (SPE-LC-MS/MS). Talanta 81 (2010), 355–366, 10.1016/j.talanta.2009.12.009.
    • (2010) Talanta , vol.81 , pp. 355-366
    • Galán, M.J.G.1    Cruz, M.S.D.2    Barceló, D.3
  • 103
    • 76749171113 scopus 로고    scopus 로고
    • Simultaneous occurrence of nitrates and sulfonamide antibiotics in two ground water bodies of Catalonia (Spain)
    • Galán, M.J.G., Garrido, T., Fraile, J., et al. Simultaneous occurrence of nitrates and sulfonamide antibiotics in two ground water bodies of Catalonia (Spain). J. Hydrol. 383 (2010), 93–101, 10.1016/j.jhydrol.2009.06.042.
    • (2010) J. Hydrol. , vol.383 , pp. 93-101
    • Galán, M.J.G.1    Garrido, T.2    Fraile, J.3
  • 104
    • 77953479496 scopus 로고    scopus 로고
    • LC-QqLIT MS analysis of nine sulfonamides and one of their acetylated metabolites in the Llobregat River basin. Quantitative determination and qualitative evaluation by IDA experiments
    • Galán, M.J.G., Villagrasa, M., Cruz, M.S.D., Barceló, D., LC-QqLIT MS analysis of nine sulfonamides and one of their acetylated metabolites in the Llobregat River basin. Quantitative determination and qualitative evaluation by IDA experiments. Anal. Bioanal. Chem. 397 (2010), 1325–1334, 10.1007/s00216-010-3630-y.
    • (2010) Anal. Bioanal. Chem. , vol.397 , pp. 1325-1334
    • Galán, M.J.G.1    Villagrasa, M.2    Cruz, M.S.D.3    Barceló, D.4
  • 105
    • 78751617371 scopus 로고    scopus 로고
    • Occurrence of sulfonamide residues along the Ebro River basin: removal in wastewater treatment plants and environmental impact assessment
    • Galán, M.J.G., Cruz, M.S.D., Barceló, D., Occurrence of sulfonamide residues along the Ebro River basin: removal in wastewater treatment plants and environmental impact assessment. Environ. Int. 37 (2011), 462–473, 10.1016/j.envint.2010.11.011.
    • (2011) Environ. Int. , vol.37 , pp. 462-473
    • Galán, M.J.G.1    Cruz, M.S.D.2    Barceló, D.3
  • 106
    • 84865832314 scopus 로고    scopus 로고
    • Ecotoxicity evaluation and removal of sulfonamides and their acetylated metabolites during conventional wastewater treatment
    • Galán, M.J.G., Blanco, S.G., Roldán, R.L., et al. Ecotoxicity evaluation and removal of sulfonamides and their acetylated metabolites during conventional wastewater treatment. Sci. Total Environ. 437 (2012), 403–412, 10.1016/j.scitotenv.2012.08.038.
    • (2012) Sci. Total Environ. , vol.437 , pp. 403-412
    • Galán, M.J.G.1    Blanco, S.G.2    Roldán, R.L.3
  • 107
    • 84957809775 scopus 로고    scopus 로고
    • Advanced oxidation of the antibiotic sulfapyridine by UV/H2O2: Characterization of its transformation products and ecotoxicological implications
    • Galán, M.J.G., Anfruns, A., Olmos, R.G., et al. Advanced oxidation of the antibiotic sulfapyridine by UV/H2O2: Characterization of its transformation products and ecotoxicological implications. Chemosphere 147 (2016), 451–459, 10.1016/j.chemosphere.2015.12.108.
    • (2016) Chemosphere , vol.147 , pp. 451-459
    • Galán, M.J.G.1    Anfruns, A.2    Olmos, R.G.3
  • 108
    • 84865596125 scopus 로고    scopus 로고
    • The significance of hazardous chemicals in wastewater treatment works effluents
    • Gardner, M., Comber, S., Scrimshaw, M.D., et al. The significance of hazardous chemicals in wastewater treatment works effluents. Sci. Total Environ. 437 (2012), 363–372, 10.1016/j.scitotenv.2012.07.086.
    • (2012) Sci. Total Environ. , vol.437 , pp. 363-372
    • Gardner, M.1    Comber, S.2    Scrimshaw, M.D.3
  • 109
    • 4043059187 scopus 로고    scopus 로고
    • Trace determination of macrolide and sulfonamide antimicrobials, a human sulfonamide metabolite, and trimethoprim in wastewater using liquid chromatography coupled to electrospray tandem mass spectrometry
    • Göbel, A., McArdell, C.S., Suter, M.J.F., Giger, W., Trace determination of macrolide and sulfonamide antimicrobials, a human sulfonamide metabolite, and trimethoprim in wastewater using liquid chromatography coupled to electrospray tandem mass spectrometry. Anal. Chem. 76 (2004), 4756–4764, 10.1021/ac0496603.
    • (2004) Anal. Chem. , vol.76 , pp. 4756-4764
    • Göbel, A.1    McArdell, C.S.2    Suter, M.J.F.3    Giger, W.4
  • 110
    • 0035417208 scopus 로고    scopus 로고
    • Trace Determination of Fluoroquinolone Antibacterial Agents in Urban Wastewater by Solid-Phase Extraction and Liquid Chromatography with Fluorescence Detection
    • Golet, E.M., Alder, A.C., Hartmann, A., et al. Trace Determination of Fluoroquinolone Antibacterial Agents in Urban Wastewater by Solid-Phase Extraction and Liquid Chromatography with Fluorescence Detection. Anal. Chem. 73 (2001), 3632–3638, 10.1021/ac0015265.
    • (2001) Anal. Chem. , vol.73 , pp. 3632-3638
    • Golet, E.M.1    Alder, A.C.2    Hartmann, A.3
  • 111
    • 0036711595 scopus 로고    scopus 로고
    • Environmental exposure and risk assessment of fluoroquinolone antibacterial agents in wastewater and river water of the Glatt Valley Watershed, Switzerland
    • Golet, E.M., Alder, A.C., Giger, W., Environmental exposure and risk assessment of fluoroquinolone antibacterial agents in wastewater and river water of the Glatt Valley Watershed, Switzerland. Environ. Sci. Technol. 36 (2002), 3645–3651, 10.1021/es0256212.
    • (2002) Environ. Sci. Technol. , vol.36 , pp. 3645-3651
    • Golet, E.M.1    Alder, A.C.2    Giger, W.3
  • 112
    • 84903585487 scopus 로고    scopus 로고
    • Seasonal changes in antibiotics, antidepressants/psychiatric drugs, antihistamines and lipid regulators in a wastewater treatment plant
    • Golovko, O., Kumar, V., Fedorova, G., et al. Seasonal changes in antibiotics, antidepressants/psychiatric drugs, antihistamines and lipid regulators in a wastewater treatment plant. Chemosphere 111 (2014), 418–426, 10.1016/j.chemosphere.2014.03.132.
    • (2014) Chemosphere , vol.111 , pp. 418-426
    • Golovko, O.1    Kumar, V.2    Fedorova, G.3
  • 113
    • 33646075711 scopus 로고    scopus 로고
    • Determination of pharmaceuticals of various therapeutic classes by solid-phase extraction and liquid chromatography-tandem mass spectrometry analysis in hospital effluent wastewaters
    • Gómez, M.J., Petrović, M., Alba, A.R.F., Barceló, D., Determination of pharmaceuticals of various therapeutic classes by solid-phase extraction and liquid chromatography-tandem mass spectrometry analysis in hospital effluent wastewaters. J. Chromatogr. A 1114 (2006), 224–233, 10.1016/j.chroma.2006.02.038.
    • (2006) J. Chromatogr. A , vol.1114 , pp. 224-233
    • Gómez, M.J.1    Petrović, M.2    Alba, A.R.F.3    Barceló, D.4
  • 114
    • 80055048524 scopus 로고    scopus 로고
    • Presence and biological effects of emerging contaminants in Llobregat River basin: A review
    • González, S., López-Roldán, R., Cortina, J.L., Presence and biological effects of emerging contaminants in Llobregat River basin: A review. Environ. Pollut. 161 (2012), 83–92, 10.1016/j.envpol.2011.10.002.
    • (2012) Environ. Pollut. , vol.161 , pp. 83-92
    • González, S.1    López-Roldán, R.2    Cortina, J.L.3
  • 115
    • 84900531005 scopus 로고    scopus 로고
    • Input of pharmaceuticals through coastal surface watercourses into a Mediterranean Lagoon (Mar Menor, SE Spain): Sources and seasonal variations
    • González, R.M., Mozaz, S.R., Gros, M., et al. Input of pharmaceuticals through coastal surface watercourses into a Mediterranean Lagoon (Mar Menor, SE Spain): Sources and seasonal variations. Sci. Total Environ. 490 (2014), 59–72, 10.1016/j.scitotenv.2014.04.097.
    • (2014) Sci. Total Environ. , vol.490 , pp. 59-72
    • González, R.M.1    Mozaz, S.R.2    Gros, M.3
  • 116
    • 84924327774 scopus 로고    scopus 로고
    • Seasonal distribution of pharmaceuticals in marine water and sediment from a Mediterranean coastal lagoon (SE Spain)
    • González, R.M., Mozaz, S.R., Gros, M., et al. Seasonal distribution of pharmaceuticals in marine water and sediment from a Mediterranean coastal lagoon (SE Spain). Environ. Res. 138 (2015), 326–344, 10.1016/j.envres.2015.02.016.
    • (2015) Environ. Res. , vol.138 , pp. 326-344
    • González, R.M.1    Mozaz, S.R.2    Gros, M.3
  • 117
    • 84928108139 scopus 로고    scopus 로고
    • Antibiotic pollution in the environment: A review
    • Gothwal, R., Shashidhar, T., Antibiotic pollution in the environment: A review. Clean Soil, Air, Water 43 (2015), 479–489, 10.1002/clen.201300989.
    • (2015) Clean Soil, Air, Water , vol.43 , pp. 479-489
    • Gothwal, R.1    Shashidhar, T.2
  • 118
    • 78649709002 scopus 로고    scopus 로고
    • Coping with antibiotic resistance: The impending crisis
    • Gould, I.M., Coping with antibiotic resistance: The impending crisis. Int. J. Antimicrob. Agents 36 (2010), S1–S2, 10.1016/S0924-8579(10)00497-8.
    • (2010) Int. J. Antimicrob. Agents , vol.36 , pp. S1-S2
    • Gould, I.M.1
  • 119
    • 84869008537 scopus 로고    scopus 로고
    • Multi-residue method for trace level determination of pharmaceuticals in environmental samples using liquid chromatography coupled to triple quadrupole mass spectrometry
    • Grabic, R., Fick, J., Lindberg, R.H., et al. Multi-residue method for trace level determination of pharmaceuticals in environmental samples using liquid chromatography coupled to triple quadrupole mass spectrometry. Talanta 100 (2012), 183–195, 10.1016/j.talanta.2012.08.032.
    • (2012) Talanta , vol.100 , pp. 183-195
    • Grabic, R.1    Fick, J.2    Lindberg, R.H.3
  • 120
    • 84858787600 scopus 로고    scopus 로고
    • Magic bullets and moving targets: Antibiotic resistance and experimental chemotherapy, 1900-1940
    • Gradmann, C., Magic bullets and moving targets: Antibiotic resistance and experimental chemotherapy, 1900-1940. Dynamis 31 (2011), 305–321.
    • (2011) Dynamis , vol.31 , pp. 305-321
    • Gradmann, C.1
  • 121
    • 77952670204 scopus 로고    scopus 로고
    • Comparing the sensitivity of algal, cyanobacterial and bacterial bioassays to different groups of antibiotics
    • Grinten, E.V., Pikkemaat, M.G., Brandhof, E.J.V., et al. Comparing the sensitivity of algal, cyanobacterial and bacterial bioassays to different groups of antibiotics. Chemosphere 80 (2010), 1–6, 10.1016/j.chemosphere.2010.04.011.
    • (2010) Chemosphere , vol.80 , pp. 1-6
    • Grinten, E.V.1    Pikkemaat, M.G.2    Brandhof, E.J.V.3
  • 122
    • 33846888256 scopus 로고    scopus 로고
    • Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: A review
    • Gros, M., Petrović, M., Barceló, D., Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: A review. Anal. Bioanal. Chem. 386 (2006), 941–952, 10.1007/s00216-006-0586-z.
    • (2006) Anal. Bioanal. Chem. , vol.386 , pp. 941-952
    • Gros, M.1    Petrović, M.2    Barceló, D.3
  • 123
    • 33748952649 scopus 로고    scopus 로고
    • Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and wastewaters
    • Gros, M., Petrović, M., Barceló, D., Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and wastewaters. Talanta 70 (2006), 678–690, 10.1016/j.talanta.2006.05.024.
    • (2006) Talanta , vol.70 , pp. 678-690
    • Gros, M.1    Petrović, M.2    Barceló, D.3
  • 124
    • 34547945842 scopus 로고    scopus 로고
    • Wastewater treatment plants as a pathway for aquatic contamination by pharmaceuticals in the Ebro River Basin (Northeast Spain)
    • Gros, M., Petrović, M., Barceló, D., Wastewater treatment plants as a pathway for aquatic contamination by pharmaceuticals in the Ebro River Basin (Northeast Spain). Environ. Toxicol. Chem. 26 (2007), 1553–1562, 10.1897/06-495R.1.
    • (2007) Environ. Toxicol. Chem. , vol.26 , pp. 1553-1562
    • Gros, M.1    Petrović, M.2    Barceló, D.3
  • 125
    • 84863110519 scopus 로고    scopus 로고
    • Fast and comprehensive multi-residue analysis of a broad range of human and veterinary pharmaceuticals and some of their metabolites in surface and treated waters by ultra-high-performance liquid chromatography coupled to quadrupole-linear ion trap tandem
    • Gros, M., Mozaz, S.R., Barceló, D., Fast and comprehensive multi-residue analysis of a broad range of human and veterinary pharmaceuticals and some of their metabolites in surface and treated waters by ultra-high-performance liquid chromatography coupled to quadrupole-linear ion trap tandem. J. Chromatogr. A 1248 (2012), 104–121, 10.1016/j.chroma.2012.05.084.
    • (2012) J. Chromatogr. A , vol.1248 , pp. 104-121
    • Gros, M.1    Mozaz, S.R.2    Barceló, D.3
  • 126
    • 84877147628 scopus 로고    scopus 로고
    • Rapid analysis of multiclass antibiotic residues and some of their metabolites in hospital, urban wastewater and river water by ultra-high performance liquid chromatography coupled to quadrupole-linear ion trap tandem mass spectrometry
    • Gros, M., Mozaz, S.R., Barceló, D., Rapid analysis of multiclass antibiotic residues and some of their metabolites in hospital, urban wastewater and river water by ultra-high performance liquid chromatography coupled to quadrupole-linear ion trap tandem mass spectrometry. J. Chromatogr. A 1292 (2013), 173–188, 10.1016/j.chroma.2012.12.072.
    • (2013) J. Chromatogr. A , vol.1292 , pp. 173-188
    • Gros, M.1    Mozaz, S.R.2    Barceló, D.3
  • 127
    • 84890695461 scopus 로고    scopus 로고
    • Antibiotics in crisis
    • Gross, M., Antibiotics in crisis. Curr. Biol. 23 (2013), R1063–R1065, 10.1016/j.cub.2013.11.057.
    • (2013) Curr. Biol. , vol.23 , pp. R1063-R1065
    • Gross, M.1
  • 128
    • 0032487090 scopus 로고    scopus 로고
    • Antimicrobial resistance in developing countries
    • Hart, C.A., Kariuki, S., Antimicrobial resistance in developing countries. Br. Med. J. 317 (1998), 647–650.
    • (1998) Br. Med. J. , vol.317 , pp. 647-650
    • Hart, C.A.1    Kariuki, S.2
  • 129
    • 33847411873 scopus 로고    scopus 로고
    • Application of molecularly imprinted polymers to solid-phase extraction of analytes from real samples
    • He, C., Long, Y., Pan, J., et al. Application of molecularly imprinted polymers to solid-phase extraction of analytes from real samples. J. Biochem. Biophys. Methods 70 (2007), 133–150, 10.1016/j.trac.2005.05.008.
    • (2007) J. Biochem. Biophys. Methods , vol.70 , pp. 133-150
    • He, C.1    Long, Y.2    Pan, J.3
  • 130
    • 84923591839 scopus 로고    scopus 로고
    • Detection of a wide variety of human and veterinary fluoroquinolone antibiotics in municipal wastewater and wastewater-impacted surface water
    • He, K., Soares, A.D., Adejumo, H., et al. Detection of a wide variety of human and veterinary fluoroquinolone antibiotics in municipal wastewater and wastewater-impacted surface water. J. Pharm. Biomed. Anal. 106 (2015), 136–143, 10.1016/j.jpba.2014.11.020.
    • (2015) J. Pharm. Biomed. Anal. , vol.106 , pp. 136-143
    • He, K.1    Soares, A.D.2    Adejumo, H.3
  • 131
    • 0037052865 scopus 로고    scopus 로고
    • Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: A review of recent research data
    • Heberer, T., Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: A review of recent research data. Toxicol. Lett. 131 (2002), 5–17, 10.1016/S0378-4274(02)00041-3.
    • (2002) Toxicol. Lett. , vol.131 , pp. 5-17
    • Heberer, T.1
  • 132
    • 36348972173 scopus 로고
    • The mode of action of sulfonamides
    • Henry, R.J., The mode of action of sulfonamides. Bacteriol. Rev. 7 (1943), 175–262.
    • (1943) Bacteriol. Rev. , vol.7 , pp. 175-262
    • Henry, R.J.1
  • 133
    • 34250026940 scopus 로고    scopus 로고
    • Antibiotic residue determination in environmental waters by LC-MS
    • Hernández, F., Sancho, J.V., Ibáñez, M., Guerrero, C., Antibiotic residue determination in environmental waters by LC-MS. Trends Anal. Chem. 26 (2007), 466–485, 10.1016/j.trac.2007.01.012.
    • (2007) Trends Anal. Chem. , vol.26 , pp. 466-485
    • Hernández, F.1    Sancho, J.V.2    Ibáñez, M.3    Guerrero, C.4
  • 134
    • 31944449816 scopus 로고    scopus 로고
    • Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments
    • Hernando, M.D., Mezcua, M., Fernández-Alba, A.R., Barceló, D., Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments. Talanta 69 (2006), 334–342, 10.1016/j.talanta.2005.09.037.
    • (2006) Talanta , vol.69 , pp. 334-342
    • Hernando, M.D.1    Mezcua, M.2    Fernández-Alba, A.R.3    Barceló, D.4
  • 135
    • 0141792748 scopus 로고    scopus 로고
    • Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography–electrospray tandem mass spectrometry
    • Hilton, M.J., Thomas, K.V., Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography–electrospray tandem mass spectrometry. J. Chromatogr. A 1015 (2003), 129–141, 10.1016/S0021-9673(03)01213-5.
    • (2003) J. Chromatogr. A , vol.1015 , pp. 129-141
    • Hilton, M.J.1    Thomas, K.V.2
  • 136
    • 0033011062 scopus 로고    scopus 로고
    • Occurrence of antibiotics in the aquatic environment
    • Hirsch, R., Ternes, T., Haberer, K., Kratz, K.L., Occurrence of antibiotics in the aquatic environment. Sci. Total Environ. 225 (1999), 109–118, 10.1016/S0048-9697(98)00337-4.
    • (1999) Sci. Total Environ. , vol.225 , pp. 109-118
    • Hirsch, R.1    Ternes, T.2    Haberer, K.3    Kratz, K.L.4
  • 137
    • 57849119195 scopus 로고    scopus 로고
    • Accurate mass screening and identification of emerging contaminants in environmental samples by liquid chromatography-hybrid linear ion trap Orbitrap mass spectrometry
    • Hogenboom, A.C., van Leerdam, J.A., Voogt, P., Accurate mass screening and identification of emerging contaminants in environmental samples by liquid chromatography-hybrid linear ion trap Orbitrap mass spectrometry. J. Chromatogr. A 1216 (2009), 510–519, 10.1016/j.chroma.2008.08.053.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 510-519
    • Hogenboom, A.C.1    van Leerdam, J.A.2    Voogt, P.3
  • 138
    • 79960836675 scopus 로고    scopus 로고
    • Degradation and removal methods of antibiotics from aqueous matrices: A review
    • Homem, V., Santos, L., Degradation and removal methods of antibiotics from aqueous matrices: A review. J. Environ. Manag. 92 (2011), 2304–2347, 10.1016/j.jenvman.2011.05.023.
    • (2011) J. Environ. Manag. , vol.92 , pp. 2304-2347
    • Homem, V.1    Santos, L.2
  • 139
    • 84922422847 scopus 로고    scopus 로고
    • Development and validation of a fast procedure to analyze amoxicillin in river waters by direct-injection LC-MS/MS
    • Homem, V., Alves, A., Santos, L., Development and validation of a fast procedure to analyze amoxicillin in river waters by direct-injection LC-MS/MS. J. Chem. Educ. 91 (2014), 1961–1965, 10.1021/ed500482j.
    • (2014) J. Chem. Educ. , vol.91 , pp. 1961-1965
    • Homem, V.1    Alves, A.2    Santos, L.3
  • 140
    • 34447626604 scopus 로고    scopus 로고
    • Multiresidue method for the determination of basic/neutral pharmaceuticals and illicit drugs in surface water by solid-phase extraction and ultra performance liquid chromatography-positive electrospray ionisation tandem mass spectrometry
    • Hordern, B.K., Dinsdale, R.M., Guwy, A.J., Multiresidue method for the determination of basic/neutral pharmaceuticals and illicit drugs in surface water by solid-phase extraction and ultra performance liquid chromatography-positive electrospray ionisation tandem mass spectrometry. J. Chromatogr. A 1161 (2007), 132–145, 10.1016/j.chroma.2007.05.074.
    • (2007) J. Chromatogr. A , vol.1161 , pp. 132-145
    • Hordern, B.K.1    Dinsdale, R.M.2    Guwy, A.J.3
  • 141
    • 44349136273 scopus 로고    scopus 로고
    • Multiresidue methods for the analysis of pharmaceuticals, personal care products and illicit drugs in surface water and wastewater by solid-phase extraction and ultra performance liquid chromatography-electrospray tandem mass spectrometry
    • Hordern, B.K., Dinsdale, R.M., Guwy, A.J., Multiresidue methods for the analysis of pharmaceuticals, personal care products and illicit drugs in surface water and wastewater by solid-phase extraction and ultra performance liquid chromatography-electrospray tandem mass spectrometry. Anal. Bioanal. Chem. 391 (2008), 1293–1308, 10.1007/s00216-008-1854-x.
    • (2008) Anal. Bioanal. Chem. , vol.391 , pp. 1293-1308
    • Hordern, B.K.1    Dinsdale, R.M.2    Guwy, A.J.3
  • 142
    • 38149076374 scopus 로고    scopus 로고
    • The effect of signal suppression and mobile phase composition on the simultaneous analysis of multiple classes of acidic/neutral pharmaceuticals and personal care products in surface water by solid-phase extraction and ultra performance liquid chromatogra
    • Hordern, B.K., Dinsdale, R.M., Guwy, A.J., The effect of signal suppression and mobile phase composition on the simultaneous analysis of multiple classes of acidic/neutral pharmaceuticals and personal care products in surface water by solid-phase extraction and ultra performance liquid chromatogra. Talanta 74 (2008), 1299–1312, 10.1016/j.talanta.2007.08.037.
    • (2008) Talanta , vol.74 , pp. 1299-1312
    • Hordern, B.K.1    Dinsdale, R.M.2    Guwy, A.J.3
  • 143
    • 53649084556 scopus 로고    scopus 로고
    • The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK
    • Hordern, B.K., Dinsdale, R.M., Guwy, A.J., The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK. Water Res. 42 (2008), 3498–3518, 10.1016/j.watres.2008.04.026.
    • (2008) Water Res. , vol.42 , pp. 3498-3518
    • Hordern, B.K.1    Dinsdale, R.M.2    Guwy, A.J.3
  • 144
    • 58549120162 scopus 로고    scopus 로고
    • The removal of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs during wastewater treatment and its impact on the quality of receiving waters
    • Hordern, B.K., Dinsdale, R.M., Guwy, A.J., The removal of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs during wastewater treatment and its impact on the quality of receiving waters. Water Res. 43 (2009), 363–380, 10.1016/j.watres.2008.10.047.
    • (2009) Water Res. , vol.43 , pp. 363-380
    • Hordern, B.K.1    Dinsdale, R.M.2    Guwy, A.J.3
  • 145
    • 84869865802 scopus 로고    scopus 로고
    • Multiresidue analysis of 88 polar organic micropollutants in ground, surface and wastewater using online mixed-bed multilayer solid-phase extraction coupled to high performance liquid chromatography–tandem mass spectrometry
    • Huntscha, S., Singer, H.P., McArdell, C.S., et al. Multiresidue analysis of 88 polar organic micropollutants in ground, surface and wastewater using online mixed-bed multilayer solid-phase extraction coupled to high performance liquid chromatography–tandem mass spectrometry. J. Chromatogr. A 1268 (2012), 74–83, 10.1016/j.chroma.2012.10.032.
    • (2012) J. Chromatogr. A , vol.1268 , pp. 74-83
    • Huntscha, S.1    Singer, H.P.2    McArdell, C.S.3
  • 146
    • 84886086435 scopus 로고    scopus 로고
    • Determination of the presence of three antimicrobials in surface water collected from urban and rural areas
    • Iglesias, A., Nebot, C., Miranda, J.M., et al. Determination of the presence of three antimicrobials in surface water collected from urban and rural areas. Antibiotics 2 (2013), 46–57, 10.3390/antibiotics2010046.
    • (2013) Antibiotics , vol.2 , pp. 46-57
    • Iglesias, A.1    Nebot, C.2    Miranda, J.M.3
  • 147
    • 84904914652 scopus 로고    scopus 로고
    • Evaluation of pharmaceuticals in surface water: reliability of PECs compared to MECs
    • Jeanton, H.C., Schemberg, D., Mohammed, N., et al. Evaluation of pharmaceuticals in surface water: reliability of PECs compared to MECs. Environ. Int. 73 (2014), 10–21, 10.1016/j.envint.2014.06.015.
    • (2014) Environ. Int. , vol.73 , pp. 10-21
    • Jeanton, H.C.1    Schemberg, D.2    Mohammed, N.3
  • 148
    • 78650917499 scopus 로고    scopus 로고
    • Occurrence, distribution and seasonal variation of antibiotics in the Huangpu River, Shanghai, China
    • Jiang, L., Hu, X., Yin, D., et al. Occurrence, distribution and seasonal variation of antibiotics in the Huangpu River, Shanghai, China. Chemosphere 82 (2011), 822–828, 10.1016/j.chemosphere.2010.11.028.
    • (2011) Chemosphere , vol.82 , pp. 822-828
    • Jiang, L.1    Hu, X.2    Yin, D.3
  • 149
    • 84861186616 scopus 로고    scopus 로고
    • Screening and human health risk assessment of pharmaceuticals and their transformation products in Dutch surface waters and drinking water
    • Jongh, C.M., Kooij, P.J.F., de Voogt, P., et al. Screening and human health risk assessment of pharmaceuticals and their transformation products in Dutch surface waters and drinking water. Sci. Total Environ. 427-428 (2012), 70–77, 10.1016/j.scitotenv.2012.04.010.
    • (2012) Sci. Total Environ. , vol.427-428 , pp. 70-77
    • Jongh, C.M.1    Kooij, P.J.F.2    de Voogt, P.3
  • 150
    • 23744512414 scopus 로고    scopus 로고
    • Removal of pharmaceuticals and fragrances in biological wastewater treatment
    • Joss, A., Keller, E., Alder, A.C., et al. Removal of pharmaceuticals and fragrances in biological wastewater treatment. Water Res. 39 (2005), 3139–3152, 10.1016/j.watres.2005.05.031.
    • (2005) Water Res. , vol.39 , pp. 3139-3152
    • Joss, A.1    Keller, E.2    Alder, A.C.3
  • 151
    • 84868699229 scopus 로고    scopus 로고
    • Emerging organic contaminants in groundwater in Spain: A review of sources, recent occurrence and fate in a European context
    • Jurado, A., Vàzquez-Suñé, E., Carrera, J., et al. Emerging organic contaminants in groundwater in Spain: A review of sources, recent occurrence and fate in a European context. Sci. Total Environ. 440 (2012), 82–94, 10.1016/j.scitotenv.2012.08.029.
    • (2012) Sci. Total Environ. , vol.440 , pp. 82-94
    • Jurado, A.1    Vàzquez-Suñé, E.2    Carrera, J.3
  • 152
    • 80555126765 scopus 로고    scopus 로고
    • Transformation products of pharmaceuticals in surface waters and wastewater formed during photolysis and advanced oxidation processes - degradation, elucidation of byproducts and assessment of their biological potency
    • Kassinos, D.F., Vasquez, M.I., Kümmerer, K., Transformation products of pharmaceuticals in surface waters and wastewater formed during photolysis and advanced oxidation processes - degradation, elucidation of byproducts and assessment of their biological potency. Chemosphere 85 (2011), 693–709, 10.1016/j.chemosphere.2011.06.082.
    • (2011) Chemosphere , vol.85 , pp. 693-709
    • Kassinos, D.F.1    Vasquez, M.I.2    Kümmerer, K.3
  • 153
    • 35148833587 scopus 로고    scopus 로고
    • Veterinary antibiotics in the aquatic and terrestrial environment
    • Kemper, N., Veterinary antibiotics in the aquatic and terrestrial environment. Ecol. Indic. 8 (2008), 1–13, 10.1016/j.ecolind.2007.06.002.
    • (2008) Ecol. Indic. , vol.8 , pp. 1-13
    • Kemper, N.1
  • 154
    • 84884373638 scopus 로고    scopus 로고
    • Sulfonamides and tetracyclines in livestock wastewater
    • Kim, H., Hong, Y., Park, J., et al. Sulfonamides and tetracyclines in livestock wastewater. Chemosphere 91 (2013), 888–894, 10.1016/j.chemosphere.2013.02.027.
    • (2013) Chemosphere , vol.91 , pp. 888-894
    • Kim, H.1    Hong, Y.2    Park, J.3
  • 155
    • 18144425511 scopus 로고    scopus 로고
    • Azithromycin extraction from municipal wastewater and quantitation using liquid chromatography/mass spectrometry
    • Koch, D.E., Bhandari, A., Close, L., Hunter, R.P., Azithromycin extraction from municipal wastewater and quantitation using liquid chromatography/mass spectrometry. J. Chromatogr. A 1074 (2005), 17–22, 10.1016/j.chroma.2005.03.052.
    • (2005) J. Chromatogr. A , vol.1074 , pp. 17-22
    • Koch, D.E.1    Bhandari, A.2    Close, L.3    Hunter, R.P.4
  • 156
    • 84881491541 scopus 로고    scopus 로고
    • Investigation of PPCPs in wastewater treatment plants in Greece: occurrence, removal and environmental risk assessment
    • Kosma, C.I., Lambropoulou, D.A., Albanis, T.A., Investigation of PPCPs in wastewater treatment plants in Greece: occurrence, removal and environmental risk assessment. Sci. Total Environ. 466-467 (2014), 421–438, 10.1016/j.scitotenv.2013.07.044.
    • (2014) Sci. Total Environ. , vol.466-467 , pp. 421-438
    • Kosma, C.I.1    Lambropoulou, D.A.2    Albanis, T.A.3
  • 157
    • 56449124646 scopus 로고    scopus 로고
    • Analytical problems and the need for sample preparation in the determination of pharmaceuticals and their metabolites in aqueous environmental matrices
    • Kostopoulou, M., Nikolaou, A., Analytical problems and the need for sample preparation in the determination of pharmaceuticals and their metabolites in aqueous environmental matrices. Trends Anal. Chem. 27 (2008), 1023–1035, 10.1016/j.trac.2008.09.011.
    • (2008) Trends Anal. Chem. , vol.27 , pp. 1023-1035
    • Kostopoulou, M.1    Nikolaou, A.2
  • 158
    • 0038601519 scopus 로고    scopus 로고
    • Significance of antibiotics in the environment
    • Kümmerer, K., Significance of antibiotics in the environment. J. Antimicrob. Chemother. 52 (2003), 5–7, 10.1093/jac/dkg293.
    • (2003) J. Antimicrob. Chemother. , vol.52 , pp. 5-7
    • Kümmerer, K.1
  • 159
    • 67349114112 scopus 로고    scopus 로고
    • The presence of pharmaceuticals in the environment due to human use: Present knowledge and future challenges
    • Kümmerer, K., The presence of pharmaceuticals in the environment due to human use: Present knowledge and future challenges. J. Environ. Manag. 90 (2009), 2354–2366, 10.1016/j.jenvman.2009.01.023.
    • (2009) J. Environ. Manag. , vol.90 , pp. 2354-2366
    • Kümmerer, K.1
  • 160
    • 63449084512 scopus 로고    scopus 로고
    • Antibiotics in the aquatic environment: A review - Part I
    • Kümmerer, K., Antibiotics in the aquatic environment: A review - Part I. Chemosphere 75 (2009), 417–434, 10.1016/j.chemosphere.2008.11.086.
    • (2009) Chemosphere , vol.75 , pp. 417-434
    • Kümmerer, K.1
  • 161
    • 63449089595 scopus 로고    scopus 로고
    • Antibiotics in the aquatic environment: A review - Part II
    • Kümmerer, K., Antibiotics in the aquatic environment: A review - Part II. Chemosphere 75 (2009), 435–441, 10.1016/j.chemosphere.2008.12.006.
    • (2009) Chemosphere , vol.75 , pp. 435-441
    • Kümmerer, K.1
  • 162
    • 77953356047 scopus 로고    scopus 로고
    • Relating environmental concentrations of pharmaceuticals to consumption: A mass balance approach for the River Rhine
    • Laak, T.L., Aa, M., Houtman, C.J., et al. Relating environmental concentrations of pharmaceuticals to consumption: A mass balance approach for the River Rhine. Environ. Int. 36 (2010), 403–409, 10.1016/j.envint.2010.02.009.
    • (2010) Environ. Int. , vol.36 , pp. 403-409
    • Laak, T.L.1    Aa, M.2    Houtman, C.J.3
  • 163
    • 0032977537 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of the nitroimidazole antimicrobials
    • Lamp, K.C., Freeman, C.D., Klutman, N.E., Lacy, M.K., Pharmacokinetics and pharmacodynamics of the nitroimidazole antimicrobials. Clin. Pharmacokinet. 36 (1999), 353–373, 10.2165/00003088-199936050-00004.
    • (1999) Clin. Pharmacokinet. , vol.36 , pp. 353-373
    • Lamp, K.C.1    Freeman, C.D.2    Klutman, N.E.3    Lacy, M.K.4
  • 164
    • 63049132466 scopus 로고    scopus 로고
    • Deactivation and transformation products in biodegradability testing of beta-lactams amoxicillin and piperacillin
    • Längin, A., Alexy, R., König, A., Kümmerer, K., Deactivation and transformation products in biodegradability testing of beta-lactams amoxicillin and piperacillin. Chemosphere 75 (2009), 347–354, 10.1016/j.chemosphere.2008.12.032.
    • (2009) Chemosphere , vol.75 , pp. 347-354
    • Längin, A.1    Alexy, R.2    König, A.3    Kümmerer, K.4
  • 165
    • 84856446159 scopus 로고    scopus 로고
    • Emerging organic contaminants in groundwater: A review of sources, fate and occurrence
    • Lapworth, D.J., Baran, N., Stuart, M.E., Ward, R.S., Emerging organic contaminants in groundwater: A review of sources, fate and occurrence. Environ. Pollut. 163 (2012), 287–303, 10.1016/j.envpol.2011.12.034.
    • (2012) Environ. Pollut. , vol.163 , pp. 287-303
    • Lapworth, D.J.1    Baran, N.2    Stuart, M.E.3    Ward, R.S.4
  • 166
    • 0026666065 scopus 로고
    • Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives
    • Lau, A.H., Lam, N.P., Piscitelli, S.C., et al. Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives. Clin. Pharmacokinet. 23 (1992), 328–364, 10.2165/00003088-199223050-00002.
    • (1992) Clin. Pharmacokinet. , vol.23 , pp. 328-364
    • Lau, A.H.1    Lam, N.P.2    Piscitelli, S.C.3
  • 167
    • 77955267759 scopus 로고    scopus 로고
    • Fate of antibiotics during municipal water recycling treatment processes
    • Le-Minh, N., Khan, S.J., Drewes, J.E., Stuetz, R.M., Fate of antibiotics during municipal water recycling treatment processes. Water Res. 44 (2010), 4295–4323, 10.1016/j.watres.2010.06.020.
    • (2010) Water Res. , vol.44 , pp. 4295-4323
    • Le-Minh, N.1    Khan, S.J.2    Drewes, J.E.3    Stuetz, R.M.4
  • 168
    • 58049203865 scopus 로고    scopus 로고
    • Needs for reliable analytical methods for monitoring chemical pollutants in surface water under the European Water Framework Directive
    • Lepom, P., Brown, B., Hanke, G., et al. Needs for reliable analytical methods for monitoring chemical pollutants in surface water under the European Water Framework Directive. J. Chromatogr. A 1216 (2009), 302–315, 10.1016/j.chroma.2008.06.017.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 302-315
    • Lepom, P.1    Brown, B.2    Hanke, G.3
  • 169
    • 84858448162 scopus 로고    scopus 로고
    • Distribution, fate and risk assessment of antibiotics in sewage treatment plants in Hong Kong, South China
    • Leung, H.W., Minh, T.B., Murphy, M.B., et al. Distribution, fate and risk assessment of antibiotics in sewage treatment plants in Hong Kong, South China. Environ. Int. 42 (2012), 1–9, 10.1016/j.envint.2011.03.004.
    • (2012) Environ. Int. , vol.42 , pp. 1-9
    • Leung, H.W.1    Minh, T.B.2    Murphy, M.B.3
  • 170
    • 0030624532 scopus 로고    scopus 로고
    • Antibiotic resistance: An ecological imbalance
    • Levy, S.B., Antibiotic resistance: An ecological imbalance. CIBA Found. Symp. 207 (1997), 1–9.
    • (1997) CIBA Found. Symp. , vol.207 , pp. 1-9
    • Levy, S.B.1
  • 171
    • 0036151784 scopus 로고    scopus 로고
    • Factors impacting on the problem of antibiotic resistance
    • Levy, S.B., Factors impacting on the problem of antibiotic resistance. J. Antimicrob. Chemother. 49 (2002), 25–30, 10.1093/jac/49.1.25.
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 25-30
    • Levy, S.B.1
  • 172
    • 84896739148 scopus 로고    scopus 로고
    • Occurrence, sources, and fate of pharmaceuticals in aquatic environment and soil
    • Li, W.C., Occurrence, sources, and fate of pharmaceuticals in aquatic environment and soil. Environ. Pollut. 187 (2014), 193–201, 10.1016/j.envpol.2014.01.015.
    • (2014) Environ. Pollut. , vol.187 , pp. 193-201
    • Li, W.C.1
  • 173
    • 84906943205 scopus 로고    scopus 로고
    • Acute toxicity evaluation for quinolone antibiotics and their chlorination disinfection processes
    • Li, M., Wei, D., Du, Y., Acute toxicity evaluation for quinolone antibiotics and their chlorination disinfection processes. J. Environ. Sci. 26 (2014), 1837–1842, 10.1016/j.jes.2014.06.023.
    • (2014) J. Environ. Sci. , vol.26 , pp. 1837-1842
    • Li, M.1    Wei, D.2    Du, Y.3
  • 174
    • 0346120094 scopus 로고    scopus 로고
    • Appropriate antibiotic use and why it is important: The challenges of bacterial resistance
    • Lieberman, J.M., Appropriate antibiotic use and why it is important: The challenges of bacterial resistance. Pediatr. Infect. Dis. J. 22 (2003), 1143–1151, 10.1097/01.inf.0000101851.57263.63.
    • (2003) Pediatr. Infect. Dis. J. , vol.22 , pp. 1143-1151
    • Lieberman, J.M.1
  • 175
    • 7044224486 scopus 로고    scopus 로고
    • Determination of antibiotic substances in hospital sewage water using solid phase extraction and liquid chromatography/mass spectrometry and group analogue internal standards
    • Lindberg, R., Jarnheimer, P.A., Olsen, B., et al. Determination of antibiotic substances in hospital sewage water using solid phase extraction and liquid chromatography/mass spectrometry and group analogue internal standards. Chemosphere 57 (2004), 1479–1488, 10.1016/j.chemosphere.2004.09.015.
    • (2004) Chemosphere , vol.57 , pp. 1479-1488
    • Lindberg, R.1    Jarnheimer, P.A.2    Olsen, B.3
  • 176
    • 19044394460 scopus 로고    scopus 로고
    • Screening of human antibiotic substances and determination of weekly mass flows in five sewage treatment plants in Sweden
    • Lindberg, R.H., Wennberg, P., Johansson, M.I., et al. Screening of human antibiotic substances and determination of weekly mass flows in five sewage treatment plants in Sweden. Environ. Sci. Technol. 39 (2005), 3421–3429, 10.1021/es048143z.
    • (2005) Environ. Sci. Technol. , vol.39 , pp. 3421-3429
    • Lindberg, R.H.1    Wennberg, P.2    Johansson, M.I.3
  • 177
    • 84919725056 scopus 로고    scopus 로고
    • Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap
    • Llorca, M., Mozaz, S.R., Couillerot, O., et al. Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. Chemosphere 119 (2015), 90–98, 10.1016/j.chemosphere.2014.05.072.
    • (2015) Chemosphere , vol.119 , pp. 90-98
    • Llorca, M.1    Mozaz, S.R.2    Couillerot, O.3
  • 178
    • 77954219742 scopus 로고    scopus 로고
    • Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water
    • Loos, R., Locoro, G., Comero, S., et al. Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water. Water Res. 44 (2010), 4115–4126, 10.1016/j.watres.2010.05.032.
    • (2010) Water Res. , vol.44 , pp. 4115-4126
    • Loos, R.1    Locoro, G.2    Comero, S.3
  • 179
    • 84886281750 scopus 로고    scopus 로고
    • EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents
    • Loos, R., Carvalho, R., António, D.C., et al. EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents. Water Res. 47 (2013), 6475–6487, 10.1016/j.watres.2013.08.024.
    • (2013) Water Res. , vol.47 , pp. 6475-6487
    • Loos, R.1    Carvalho, R.2    António, D.C.3
  • 180
    • 79953107369 scopus 로고    scopus 로고
    • Multi-class determination of around 50 pharmaceuticals, including 26 antibiotics, in environmental and wastewater samples by ultra-high performance liquid chromatography-tandem mass spectrometry
    • Lor, E.G., Sancho, J.V., Hernández, F., Multi-class determination of around 50 pharmaceuticals, including 26 antibiotics, in environmental and wastewater samples by ultra-high performance liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 1218 (2011), 2264–2275, 10.1016/j.chroma.2011.02.026.
    • (2011) J. Chromatogr. A , vol.1218 , pp. 2264-2275
    • Lor, E.G.1    Sancho, J.V.2    Hernández, F.3
  • 181
    • 84857801484 scopus 로고    scopus 로고
    • Occurrence and removal of pharmaceuticals in wastewater treatment plants at the Spanish Mediterranean area of Valencia
    • Lor, E.G., Sancho, J.V., Serrano, R., Hernández, F., Occurrence and removal of pharmaceuticals in wastewater treatment plants at the Spanish Mediterranean area of Valencia. Chemosphere 87 (2012), 453–462, 10.1016/j.chemosphere.2011.12.025.
    • (2012) Chemosphere , vol.87 , pp. 453-462
    • Lor, E.G.1    Sancho, J.V.2    Serrano, R.3    Hernández, F.4
  • 182
    • 0038665502 scopus 로고    scopus 로고
    • Antimicrobial resistance: the example of Staphylococcus aureus
    • Lowy, F.D., Antimicrobial resistance: the example of Staphylococcus aureus. J. Clin. Invest. 111 (2003), 1265–1273, 10.1172/JCI18535.
    • (2003) J. Clin. Invest. , vol.111 , pp. 1265-1273
    • Lowy, F.D.1
  • 183
    • 84891689980 scopus 로고    scopus 로고
    • A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment
    • Luo, Y., Guo, W., Ngo, H.H., et al. A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment. Sci. Total Environ. 473-474 (2014), 619–641, 10.1016/j.scitotenv.2013.12.065.
    • (2014) Sci. Total Environ. , vol.473-474 , pp. 619-641
    • Luo, Y.1    Guo, W.2    Ngo, H.H.3
  • 184
    • 70349248193 scopus 로고    scopus 로고
    • Pharmaceutical trace analysis in aqueous environmental matrices by liquid chromatography-ion trap tandem mass spectrometry
    • Madureira, T.V., Barreiro, J.C., Rocha, M.J., et al. Pharmaceutical trace analysis in aqueous environmental matrices by liquid chromatography-ion trap tandem mass spectrometry. J. Chromatogr. A 1216 (2009), 7033–7042, 10.1016/j.chroma.2009.08.060.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 7033-7042
    • Madureira, T.V.1    Barreiro, J.C.2    Rocha, M.J.3
  • 185
    • 84939954461 scopus 로고    scopus 로고
    • Biological plausibility as a tool to associate analytical data for micropollutants and effect potentials in wastewater, surface water, and sediments with effects in fishes
    • Maier, D., Blaha, L., Giesy, J.P., et al. Biological plausibility as a tool to associate analytical data for micropollutants and effect potentials in wastewater, surface water, and sediments with effects in fishes. Water Res. 72 (2015), 127–144, 10.1016/j.watres.2014.08.050.
    • (2015) Water Res. , vol.72 , pp. 127-144
    • Maier, D.1    Blaha, L.2    Giesy, J.P.3
  • 186
    • 84908063184 scopus 로고    scopus 로고
    • Antibacterial activity of sulfamethoxazole transformation products (TPs): General relevance for sulfonamide TPs modified at the para position
    • Majewsky, M., Wagner, D., Delay, M., et al. Antibacterial activity of sulfamethoxazole transformation products (TPs): General relevance for sulfonamide TPs modified at the para position. Chem. Res. Toxicol. 27 (2014), 1821–1828, 10.1021/tx500267x.
    • (2014) Chem. Res. Toxicol. , vol.27 , pp. 1821-1828
    • Majewsky, M.1    Wagner, D.2    Delay, M.3
  • 187
    • 84893859762 scopus 로고    scopus 로고
    • The environmental release and fate of antibiotics
    • Manzetti, S., Ghisi, R., The environmental release and fate of antibiotics. Mar. Pollut. Bull. 79 (2014), 7–15, 10.1016/j.marpolbul.2014.01.005.
    • (2014) Mar. Pollut. Bull. , vol.79 , pp. 7-15
    • Manzetti, S.1    Ghisi, R.2
  • 188
    • 69249205465 scopus 로고    scopus 로고
    • Environmental pollution by antibiotics and by antibiotic resistance determinants
    • Martinez, J.L., Environmental pollution by antibiotics and by antibiotic resistance determinants. Environ. Pollut. 157 (2009), 2893–2902, 10.1016/j.envpol.2009.05.051.
    • (2009) Environ. Pollut. , vol.157 , pp. 2893-2902
    • Martinez, J.L.1
  • 189
    • 84958559362 scopus 로고    scopus 로고
    • A review of the photodegradability and transformation products of 13 pharmaceuticals and pesticides relevant to sewage polishing treatment
    • Mathon, B., Choubert, J.-M., Miege, C., Coquery, M., A review of the photodegradability and transformation products of 13 pharmaceuticals and pesticides relevant to sewage polishing treatment. Sci. Total Environ. 551-552 (2016), 712–724, 10.1016/j.scitotenv.2016.02.009.
    • (2016) Sci. Total Environ. , vol.551-552 , pp. 712-724
    • Mathon, B.1    Choubert, J.-M.2    Miege, C.3    Coquery, M.4
  • 190
    • 0346752019 scopus 로고    scopus 로고
    • Occurrence and fate of macrolide antibiotics in wastewater treatment plants and in the Glatt Valley Watershed, Switzerland
    • McArdell, C.S., Molnar, E., Suter, M.J.F., Giger, W., Occurrence and fate of macrolide antibiotics in wastewater treatment plants and in the Glatt Valley Watershed, Switzerland. Environ. Sci. Technol. 37 (2003), 5479–5486, 10.1021/es034368i.
    • (2003) Environ. Sci. Technol. , vol.37 , pp. 5479-5486
    • McArdell, C.S.1    Molnar, E.2    Suter, M.J.F.3    Giger, W.4
  • 191
    • 84892999646 scopus 로고    scopus 로고
    • A year-long study of the spatial occurrence and relative distribution of pharmaceutical residues in sewage effluent, receiving marine waters and marine bivalves
    • McEneff, G., Barron, L., Kelleher, B., et al. A year-long study of the spatial occurrence and relative distribution of pharmaceutical residues in sewage effluent, receiving marine waters and marine bivalves. Sci. Total Environ. 476-477 (2014), 317–326, 10.1016/j.scitotenv.2013.12.123.
    • (2014) Sci. Total Environ. , vol.476-477 , pp. 317-326
    • McEneff, G.1    Barron, L.2    Kelleher, B.3
  • 192
    • 78649656501 scopus 로고    scopus 로고
    • Mediterranean wastewater reuse report
    • MED-EUWI, Mediterranean wastewater reuse report. 2007.
    • (2007)
    • MED-EUWI1
  • 193
    • 84896855479 scopus 로고    scopus 로고
    • Emerging organic contaminants in surface water and groundwater: A first overview of the situation in Italy
    • Meffe, R., de Bustamante, I., Emerging organic contaminants in surface water and groundwater: A first overview of the situation in Italy. Sci. Total Environ. 481 (2014), 280–295, 10.1016/j.scitotenv.2014.02.053.
    • (2014) Sci. Total Environ. , vol.481 , pp. 280-295
    • Meffe, R.1    de Bustamante, I.2
  • 194
    • 84927545814 scopus 로고    scopus 로고
    • Pharmaceuticals and iodinated contrast media in a hospital wastewater: A case study to analyse their presence and characterise their environmental risk and hazard
    • Mendoza, A., Aceña, J., Pérez, S., et al. Pharmaceuticals and iodinated contrast media in a hospital wastewater: A case study to analyse their presence and characterise their environmental risk and hazard. Environ. Res. 140 (2015), 225–241, 10.1016/j.envres.2015.04.003.
    • (2015) Environ. Res. , vol.140 , pp. 225-241
    • Mendoza, A.1    Aceña, J.2    Pérez, S.3
  • 195
    • 84962338951 scopus 로고    scopus 로고
    • Investigation of pharmaceuticals in processed animal by-products by liquid chromatography coupled to high-resolution mass spectrometry
    • Mestre, J.N., Ibáñez, M., Serrano, R., et al. Investigation of pharmaceuticals in processed animal by-products by liquid chromatography coupled to high-resolution mass spectrometry. Chemosphere 154 (2016), 231–239, 10.1016/j.chemosphere.2016.03.091.
    • (2016) Chemosphere , vol.154 , pp. 231-239
    • Mestre, J.N.1    Ibáñez, M.2    Serrano, R.3
  • 196
    • 84872679392 scopus 로고    scopus 로고
    • Urban wastewater treatment plants as hotspots for the release of antibiotics in the environment: A review
    • Michael, I., Rizzo, L., McArdell, C.S., et al. Urban wastewater treatment plants as hotspots for the release of antibiotics in the environment: A review. Water Res. 47 (2013), 957–995, 10.1016/j.watres.2012.11.027.
    • (2013) Water Res. , vol.47 , pp. 957-995
    • Michael, I.1    Rizzo, L.2    McArdell, C.S.3
  • 197
    • 84883534869 scopus 로고    scopus 로고
    • Occurrence of antibiotics as emerging contaminant substances in aquatic environment
    • Milić, N., Milanović, M., Letić, N.G., et al. Occurrence of antibiotics as emerging contaminant substances in aquatic environment. Int. J. Environ. Health Res. 23 (2013), 296–310, 10.1080/09603123.2012.733934.
    • (2013) Int. J. Environ. Health Res. , vol.23 , pp. 296-310
    • Milić, N.1    Milanović, M.2    Letić, N.G.3
  • 198
    • 84919723357 scopus 로고    scopus 로고
    • Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry
    • Miller, T.H., McEneff, G.L., Brown, R.J., et al. Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry. Sci. Total Environ. 511 (2015), 153–160, 10.1016/j.scitotenv.2014.12.034.
    • (2015) Sci. Total Environ. , vol.511 , pp. 153-160
    • Miller, T.H.1    McEneff, G.L.2    Brown, R.J.3
  • 199
    • 84882755074 scopus 로고    scopus 로고
    • pH and temperature effects on the hydrolysis of three β-lactam antibiotics: ampicillin, cefalotin and cefoxitin
    • Mitchell, S.M., Ullman, J.L., Teel, A.L., Watts, R.J., pH and temperature effects on the hydrolysis of three β-lactam antibiotics: ampicillin, cefalotin and cefoxitin. Sci. Total Environ. 466-467 (2014), 547–555, 10.1016/j.scitotenv.2013.06.027.
    • (2014) Sci. Total Environ. , vol.466-467 , pp. 547-555
    • Mitchell, S.M.1    Ullman, J.L.2    Teel, A.L.3    Watts, R.J.4
  • 200
    • 84896716419 scopus 로고    scopus 로고
    • Monitoring of selected priority and emerging contaminants in the Guadalquivir River and other related surface waters in the province of Jaén, South East Spain
    • Molina, J.R., López, B.G., Reyes, J.F.G., Díaz, A.M., Monitoring of selected priority and emerging contaminants in the Guadalquivir River and other related surface waters in the province of Jaén, South East Spain. Sci. Total Environ. 479-480 (2014), 247–257, 10.1016/j.scitotenv.2014.01.121.
    • (2014) Sci. Total Environ. , vol.479-480 , pp. 247-257
    • Molina, J.R.1    López, B.G.2    Reyes, J.F.G.3    Díaz, A.M.4
  • 201
    • 67349111417 scopus 로고    scopus 로고
    • Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water
    • Mompelat, S., Le Bot, B., Thomas, O., Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water. Environ. Int. 35 (2009), 803–814, 10.1016/j.envint.2008.10.008.
    • (2009) Environ. Int. , vol.35 , pp. 803-814
    • Mompelat, S.1    Le Bot, B.2    Thomas, O.3
  • 202
    • 0032779415 scopus 로고    scopus 로고
    • The advent of antibiotics: Episodes from the early days of the “miracle drugs”
    • Moore, F.D., The advent of antibiotics: Episodes from the early days of the “miracle drugs”. Surgery 126 (1999), 83–84, 10.1067/msy.1999.98701.
    • (1999) Surgery , vol.126 , pp. 83-84
    • Moore, F.D.1
  • 203
    • 84943360187 scopus 로고    scopus 로고
    • Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river
    • Mozaz, S.R., Chamorro, S., Marti, E., et al. Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river. Water Res. 69 (2015), 234–242, 10.1016/j.watres.2014.11.021.
    • (2015) Water Res. , vol.69 , pp. 234-242
    • Mozaz, S.R.1    Chamorro, S.2    Marti, E.3
  • 204
    • 70450193197 scopus 로고    scopus 로고
    • An affordable method for the simultaneous determination of the most studied pharmaceutical compounds as wastewater and surface water pollutants
    • Muñoz, D.C., Martín, J., Santos, J.L., et al. An affordable method for the simultaneous determination of the most studied pharmaceutical compounds as wastewater and surface water pollutants. J. Sep. Sci. 32 (2009), 3064–3073, 10.1002/jssc.200900128.
    • (2009) J. Sep. Sci. , vol.32 , pp. 3064-3073
    • Muñoz, D.C.1    Martín, J.2    Santos, J.L.3
  • 205
    • 77956431675 scopus 로고    scopus 로고
    • Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain)
    • Muñoz, D.C., Martín, J., Santos, J.L., et al. Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain). J. Hazard. Mater. 183 (2010), 602–608, 10.1016/j.jhazmat.2010.07.067.
    • (2010) J. Hazard. Mater. , vol.183 , pp. 602-608
    • Muñoz, D.C.1    Martín, J.2    Santos, J.L.3
  • 206
    • 84861408073 scopus 로고    scopus 로고
    • Future challenges to protecting public health from drinking water contaminants
    • Murphy, E.A., Post, G.B., Buckley, B.T., et al. Future challenges to protecting public health from drinking water contaminants. Annu. Rev. Public Health 33 (2012), 209–224, 10.1146/annurev-publhealth-031811-124506.
    • (2012) Annu. Rev. Public Health , vol.33 , pp. 209-224
    • Murphy, E.A.1    Post, G.B.2    Buckley, B.T.3
  • 207
    • 34547673014 scopus 로고    scopus 로고
    • Quantification of human pharmaceuticals in water samples by high performance liquid chromatography-tandem mass spectrometry
    • Nebot, C., Gibb, S.W., Boyd, K.G., Quantification of human pharmaceuticals in water samples by high performance liquid chromatography-tandem mass spectrometry. Anal. Chim. Acta 598 (2007), 87–94, 10.1016/j.aca.2007.07.029.
    • (2007) Anal. Chim. Acta , vol.598 , pp. 87-94
    • Nebot, C.1    Gibb, S.W.2    Boyd, K.G.3
  • 208
    • 77957018809 scopus 로고    scopus 로고
    • Development of a multi-residue analytical method, based on liquid chromatography-tandem mass spectrometry, for the simultaneous determination of 46 micro-contaminants in aqueous samples
    • Nödler, K., Licha, T., Bester, K., Sauter, M., Development of a multi-residue analytical method, based on liquid chromatography-tandem mass spectrometry, for the simultaneous determination of 46 micro-contaminants in aqueous samples. J. Chromatogr. A 1217 (2010), 6511–6521, 10.1016/j.chroma.2010.08.048.
    • (2010) J. Chromatogr. A , vol.1217 , pp. 6511-6521
    • Nödler, K.1    Licha, T.2    Bester, K.3    Sauter, M.4
  • 209
    • 84969561309 scopus 로고    scopus 로고
    • Antimicrobial resistance in G7 countries and beyond: Economic issues, policies and options for action
    • (Paris)
    • OECD, Antimicrobial resistance in G7 countries and beyond: Economic issues, policies and options for action. 2015 (Paris).
    • (2015)
    • OECD1
  • 210
    • 84989348569 scopus 로고    scopus 로고
    • S.I. No. 31/2014: European Union (Good Agricultural Practice for Protection of Waters) Regulations 2014
    • first ed. Stationery Office Dublin
    • Office of the Attorney General, S.I. No. 31/2014: European Union (Good Agricultural Practice for Protection of Waters) Regulations 2014. first ed., 2014, Stationery Office, Dublin.
    • (2014)
    • Office of the Attorney General1
  • 211
    • 78651399964 scopus 로고    scopus 로고
    • Combination of advanced oxidation processes and biological treatments for wastewater decontamination: A review
    • Oller, I., Malato, S., Sánchez-Pérez, J.A., Combination of advanced oxidation processes and biological treatments for wastewater decontamination: A review. Sci. Total Environ. 409 (2011), 414141–414166, 10.1016/j.scitotenv.2010.08.061.
    • (2011) Sci. Total Environ. , vol.409 , pp. 414141-414166
    • Oller, I.1    Malato, S.2    Sánchez-Pérez, J.A.3
  • 212
    • 33745879176 scopus 로고    scopus 로고
    • Structure-activity relationships in a series of semisynthetic polycyclic glycopeptide antibiotics
    • Olsuf'eva, E.N., Preobrazhenskaya, M.N., Structure-activity relationships in a series of semisynthetic polycyclic glycopeptide antibiotics. Russ. J. Bioorg. Chem. 32 (2006), 303–322, 10.1134/S1068162006040017.
    • (2006) Russ. J. Bioorg. Chem. , vol.32 , pp. 303-322
    • Olsuf'eva, E.N.1    Preobrazhenskaya, M.N.2
  • 213
    • 84982158532 scopus 로고    scopus 로고
    • Antimicrobial Resistance: Tackling a crisis for the health and wealth of nations
    • (London)
    • O'Neill, J., Antimicrobial Resistance: Tackling a crisis for the health and wealth of nations. 2014 (London).
    • (2014)
    • O'Neill, J.1
  • 214
    • 84878735023 scopus 로고    scopus 로고
    • Determination of some frequently used antibiotics in waste waters using solid phase extraction followed by high performance liquid chromatography with diode array and mass spectrometry detection
    • Opriş, O., Soran, M.L., Coman, V., et al. Determination of some frequently used antibiotics in waste waters using solid phase extraction followed by high performance liquid chromatography with diode array and mass spectrometry detection. Cent. Eur. J. Chem. 11 (2013), 1343–1351, 10.2478/s11532-013-0263-y.
    • (2013) Cent. Eur. J. Chem. , vol.11 , pp. 1343-1351
    • Opriş, O.1    Soran, M.L.2    Coman, V.3
  • 215
    • 84868696955 scopus 로고    scopus 로고
    • Occurrence and modeling of pharmaceuticals on a sewage-impacted Mediterranean River and their dynamics under different hydrological conditions
    • Osorio, V., Marcé, R., Pérez, S., et al. Occurrence and modeling of pharmaceuticals on a sewage-impacted Mediterranean River and their dynamics under different hydrological conditions. Sci. Total Environ. 440 (2012), 3–13, 10.1016/j.scitotenv.2012.08.040.
    • (2012) Sci. Total Environ. , vol.440 , pp. 3-13
    • Osorio, V.1    Marcé, R.2    Pérez, S.3
  • 216
    • 84945444928 scopus 로고    scopus 로고
    • Concentration and risk of pharmaceuticals in freshwater systems are related to the population density and the livestock units in Iberian Rivers
    • Osorio, V., Larrañaga, A., Aceña, J., et al. Concentration and risk of pharmaceuticals in freshwater systems are related to the population density and the livestock units in Iberian Rivers. Sci. Total Environ. 540 (2015), 267–277, 10.1016/j.scitotenv.2015.06.143.
    • (2015) Sci. Total Environ. , vol.540 , pp. 267-277
    • Osorio, V.1    Larrañaga, A.2    Aceña, J.3
  • 217
    • 12844274375 scopus 로고    scopus 로고
    • Antibiotics: Where did we go wrong?
    • Overbye, K.M., Barrett, J.F., Antibiotics: Where did we go wrong?. Drug Discov. Today 10 (2005), 45–52, 10.1016/S1359-6446(04)03285-4.
    • (2005) Drug Discov. Today , vol.10 , pp. 45-52
    • Overbye, K.M.1    Barrett, J.F.2
  • 218
    • 67349112813 scopus 로고    scopus 로고
    • Solid phase extraction coupled to liquid chromatography-tandem mass spectrometry analysis of sulfonamides, tetracyclines, analgesics and hormones in surface water and wastewater in Luxembourg
    • Pailler, J.Y., Krein, A., Pfister, L., et al. Solid phase extraction coupled to liquid chromatography-tandem mass spectrometry analysis of sulfonamides, tetracyclines, analgesics and hormones in surface water and wastewater in Luxembourg. Sci. Total Environ. 407 (2009), 4736–4743, 10.1016/j.scitotenv.2009.04.042.
    • (2009) Sci. Total Environ. , vol.407 , pp. 4736-4743
    • Pailler, J.Y.1    Krein, A.2    Pfister, L.3
  • 219
    • 84902988770 scopus 로고    scopus 로고
    • Emerging contaminants of public health significance as water quality indicator compounds in the urban water cycle
    • Pal, A., He, Y., Jekel, M., et al. Emerging contaminants of public health significance as water quality indicator compounds in the urban water cycle. Environ. Int. 71 (2014), 46–62, 10.1016/j.envint.2014.05.025.
    • (2014) Environ. Int. , vol.71 , pp. 46-62
    • Pal, A.1    He, Y.2    Jekel, M.3
  • 220
    • 84947716804 scopus 로고    scopus 로고
    • Seasonal occurrence, removal, mass loading and environmental risk assessment of 55 pharmaceuticals and personal care products in a municipal wastewater treatment plant in Central Greece
    • Papageorgiou, M., Kosma, C., Lambropoulou, D., Seasonal occurrence, removal, mass loading and environmental risk assessment of 55 pharmaceuticals and personal care products in a municipal wastewater treatment plant in Central Greece. Sci. Total Environ. 543 (2016), 547–569, 10.1016/j.scitotenv.2015.11.047.
    • (2016) Sci. Total Environ. , vol.543 , pp. 547-569
    • Papageorgiou, M.1    Kosma, C.2    Lambropoulou, D.3
  • 221
    • 84896054973 scopus 로고    scopus 로고
    • Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation
    • Pasquini, L., Munoz, J.F., Pons, M.N., et al. Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. Sci. Total Environ. 481 (2014), 459–468, 10.1016/j.scitotenv.2014.02.075.
    • (2014) Sci. Total Environ. , vol.481 , pp. 459-468
    • Pasquini, L.1    Munoz, J.F.2    Pons, M.N.3
  • 222
    • 36549041871 scopus 로고    scopus 로고
    • Sample preparation in analysis of pharmaceuticals
    • Pavlović, D.M., Babić, S., Horvat, A.J.M., Macan, M.K., Sample preparation in analysis of pharmaceuticals. Trends Anal. Chem. 26 (2007), 1062–1075, 10.1016/j.trac.2007.09.010.
    • (2007) Trends Anal. Chem. , vol.26 , pp. 1062-1075
    • Pavlović, D.M.1    Babić, S.2    Horvat, A.J.M.3    Macan, M.K.4
  • 223
    • 4644226625 scopus 로고    scopus 로고
    • The challenge of antibiotic resistant bacterial pathogens: The medical need, the market and prospects for new antimicrobial agents
    • Payne, D., Tomasz, A., The challenge of antibiotic resistant bacterial pathogens: The medical need, the market and prospects for new antimicrobial agents. Curr. Opin. Microbiol. 7 (2004), 435–438, 10.1016/j.mib.2004.08.017.
    • (2004) Curr. Opin. Microbiol. , vol.7 , pp. 435-438
    • Payne, D.1    Tomasz, A.2
  • 224
    • 36949002488 scopus 로고    scopus 로고
    • Determination of fluoroquinolone antibiotics in surface waters from Mondego River by high performance liquid chromatography using a monolithic column
    • Pena, A., Chmielova, D., Lino, C.M., Solich, P., Determination of fluoroquinolone antibiotics in surface waters from Mondego River by high performance liquid chromatography using a monolithic column. J. Sep. Sci. 30 (2007), 2924–4928, 10.1002/jssc.200700363.
    • (2007) J. Sep. Sci. , vol.30 , pp. 2924-4928
    • Pena, A.1    Chmielova, D.2    Lino, C.M.3    Solich, P.4
  • 225
    • 84911438964 scopus 로고    scopus 로고
    • Environmental impact of pharmaceuticals from Portuguese wastewaters: geographical and seasonal occurrence, removal and risk assessment
    • Pereira, A.M.P.T., Silva, L.J.G., Meisel, L.M., et al. Environmental impact of pharmaceuticals from Portuguese wastewaters: geographical and seasonal occurrence, removal and risk assessment. Environ. Res. 136 (2015), 108–119, 10.1016/j.envres.2014.09.041.
    • (2015) Environ. Res. , vol.136 , pp. 108-119
    • Pereira, A.M.P.T.1    Silva, L.J.G.2    Meisel, L.M.3
  • 226
    • 84937793253 scopus 로고    scopus 로고
    • A review on emerging contaminants in wastewaters and the environment: Current knowledge, understudied areas and recommendations for future monitoring
    • Petrie, B., Barden, R., Hordern, B.K., A review on emerging contaminants in wastewaters and the environment: Current knowledge, understudied areas and recommendations for future monitoring. Water Res. 72 (2014), 3–27, 10.1016/j.watres.2014.08.053.
    • (2014) Water Res. , vol.72 , pp. 3-27
    • Petrie, B.1    Barden, R.2    Hordern, B.K.3
  • 227
    • 33746534343 scopus 로고    scopus 로고
    • Multi-residue analysis of pharmaceuticals in wastewater by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry
    • Petrovic, M., Gros, M., Barcelo, D., Multi-residue analysis of pharmaceuticals in wastewater by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. J. Chromatogr. A 1124 (2006), 68–81, 10.1016/j.chroma.2006.05.024.
    • (2006) J. Chromatogr. A , vol.1124 , pp. 68-81
    • Petrovic, M.1    Gros, M.2    Barcelo, D.3
  • 228
    • 84875249515 scopus 로고    scopus 로고
    • Toxicity of five antibiotics and their mixtures towards photosynthetic aquatic organisms: Implications for environmental risk assessment
    • Pleiter, M.G., Gonzalo, S., Palomares, I.R., et al. Toxicity of five antibiotics and their mixtures towards photosynthetic aquatic organisms: Implications for environmental risk assessment. Water Res. 47 (2013), 2050–2064, 10.1016/j.watres.2013.01.020.
    • (2013) Water Res. , vol.47 , pp. 2050-2064
    • Pleiter, M.G.1    Gonzalo, S.2    Palomares, I.R.3
  • 229
    • 29844454206 scopus 로고    scopus 로고
    • Efficient approach for the reliable quantification and confirmation of antibiotics in water using on-line solid-phase extraction liquid chromatography/tandem mass spectrometry
    • Pozo, O.J., Guerrero, C., Sancho, J.V., et al. Efficient approach for the reliable quantification and confirmation of antibiotics in water using on-line solid-phase extraction liquid chromatography/tandem mass spectrometry. J. Chromatogr. A 1103 (2006), 83–93, 10.1016/j.chroma.2005.10.073.
    • (2006) J. Chromatogr. A , vol.1103 , pp. 83-93
    • Pozo, O.J.1    Guerrero, C.2    Sancho, J.V.3
  • 230
    • 84942604668 scopus 로고    scopus 로고
    • Spoilt for choice: A critical review on the chemical and biological assessment of current wastewater treatment technologies
    • Prasse, C., Stalter, D., Oehlmann, U.S., et al. Spoilt for choice: A critical review on the chemical and biological assessment of current wastewater treatment technologies. Water Res. 87 (2015), 237–270, 10.1016/j.watres.2015.09.023.
    • (2015) Water Res. , vol.87 , pp. 237-270
    • Prasse, C.1    Stalter, D.2    Oehlmann, U.S.3
  • 231
    • 84989356576 scopus 로고    scopus 로고
    • Sulfonamides, diaminopyrimidines, and their combinations
    • S. Giguère P. JF D. PM fifth ed. Wiley-Blackwell Hoboken
    • Prescott, J.F., Sulfonamides, diaminopyrimidines, and their combinations. Giguère, S., JF, P., PM, D., (eds.) Antimicrobial therapy in veterinary medicine, fifth ed., 2013, Wiley-Blackwell, Hoboken, 279–294.
    • (2013) Antimicrobial therapy in veterinary medicine , pp. 279-294
    • Prescott, J.F.1
  • 232
    • 84905118923 scopus 로고    scopus 로고
    • Fluoroquinolone resistance: Mechanisms, impact on bacteria, and role in evolutionary success
    • Redgrave, L.S., Sutton, S.B., Webber, M.A., Piddock, L.J.V., Fluoroquinolone resistance: Mechanisms, impact on bacteria, and role in evolutionary success. Trends Microbiol. 22 (2014), 438–445, 10.1016/j.tim.2014.04.007.
    • (2014) Trends Microbiol. , vol.22 , pp. 438-445
    • Redgrave, L.S.1    Sutton, S.B.2    Webber, M.A.3    Piddock, L.J.V.4
  • 233
    • 0042157033 scopus 로고    scopus 로고
    • Determination of antibiotic compounds in water by solid-phase extraction–high-performance liquid chromatography–(electrospray) mass spectrometry
    • Reverté, S., Borrull, F., Pocurull, E., Marcé, R.M., Determination of antibiotic compounds in water by solid-phase extraction–high-performance liquid chromatography–(electrospray) mass spectrometry. J. Chromatogr. A 1010 (2003), 225–232, 10.1016/S0021-9673(03)01064-1.
    • (2003) J. Chromatogr. A , vol.1010 , pp. 225-232
    • Reverté, S.1    Borrull, F.2    Pocurull, E.3    Marcé, R.M.4
  • 234
    • 0024355483 scopus 로고
    • Structure, biochemistry and mechanism of action of glycopeptide antibiotics
    • Reynolds, P.E., Structure, biochemistry and mechanism of action of glycopeptide antibiotics. Eur. J. Clin. Microbiol. Infect. Dis. 8 (1989), 943–950, 10.1007/BF01967563.
    • (1989) Eur. J. Clin. Microbiol. Infect. Dis. , vol.8 , pp. 943-950
    • Reynolds, P.E.1
  • 235
    • 84891090867 scopus 로고    scopus 로고
    • Effects of the antibiotic enrofloxacin on the ecology of tropical eutrophic freshwater microcosms
    • Rico, A., Dimitrov, M.R., Wijngaarden, R.P.A.V., et al. Effects of the antibiotic enrofloxacin on the ecology of tropical eutrophic freshwater microcosms. Aquat. Toxicol. 147 (2014), 92–104, 10.1016/j.aquatox.2013.12.008.
    • (2014) Aquat. Toxicol. , vol.147 , pp. 92-104
    • Rico, A.1    Dimitrov, M.R.2    Wijngaarden, R.P.A.V.3
  • 236
    • 0037059359 scopus 로고    scopus 로고
    • Sources, pathways, and relative risks of contaminants in surface water and groundwater: A perspective prepared for the Walkerton inquiry
    • Ritter, L., Solomon, K., Sibley, P., et al. Sources, pathways, and relative risks of contaminants in surface water and groundwater: A perspective prepared for the Walkerton inquiry. J. Toxicol. Environ. Health 65 (2002), 1–142.
    • (2002) J. Toxicol. Environ. Health , vol.65 , pp. 1-142
    • Ritter, L.1    Solomon, K.2    Sibley, P.3
  • 237
    • 84872679392 scopus 로고    scopus 로고
    • Urban wastewater treatment plants as hotspots for the release of antibiotics in the environment: A review
    • Rizzo, L., Manaia, C.M., Merlin, C., et al. Urban wastewater treatment plants as hotspots for the release of antibiotics in the environment: A review. Water Res. 47 (2013), 957–995, 10.1016/j.watres.2012.11.027.
    • (2013) Water Res. , vol.47 , pp. 957-995
    • Rizzo, L.1    Manaia, C.M.2    Merlin, C.3
  • 238
    • 32644485467 scopus 로고    scopus 로고
    • The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment
    • Roberts, P.H., Thomas, K.V., The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment. Sci. Total Environ. 356 (2006), 143–153, 10.1016/j.scitotenv.2005.04.031.
    • (2006) Sci. Total Environ. , vol.356 , pp. 143-153
    • Roberts, P.H.1    Thomas, K.V.2
  • 239
    • 79955552910 scopus 로고    scopus 로고
    • Assessment of the occurrence and distribution of pharmaceuticals in a Mediterranean wetland (L'Albufera, Valencia, Spain) by LC-MS/MS
    • Roig, P.V., Andreu, V., Onghena, M., et al. Assessment of the occurrence and distribution of pharmaceuticals in a Mediterranean wetland (L'Albufera, Valencia, Spain) by LC-MS/MS. Anal. Bioanal. Chem. 400 (2011), 1287–1301, 10.1007/s00216-011-4826-5.
    • (2011) Anal. Bioanal. Chem. , vol.400 , pp. 1287-1301
    • Roig, P.V.1    Andreu, V.2    Onghena, M.3
  • 240
    • 84868679907 scopus 로고    scopus 로고
    • Risk assessment on the presence of pharmaceuticals in sediments, soils and waters of the Pego-Oliva Marshlands (Valencia, eastern Spain)
    • Roig, P.V., Andreu, V., Blasco, C., Picó, Y., Risk assessment on the presence of pharmaceuticals in sediments, soils and waters of the Pego-Oliva Marshlands (Valencia, eastern Spain). Sci. Total Environ. 440 (2012), 24–32, 10.1016/j.scitotenv.2012.08.036.
    • (2012) Sci. Total Environ. , vol.440 , pp. 24-32
    • Roig, P.V.1    Andreu, V.2    Blasco, C.3    Picó, Y.4
  • 241
    • 84880733615 scopus 로고    scopus 로고
    • Antibiotics and antibiotic resistance: A bitter fight against evolution
    • Rojas, A.R., Beltrán, J.R., Couce, A., Blázquez, J., Antibiotics and antibiotic resistance: A bitter fight against evolution. Int. J. Med. Microbiol. 303 (2013), 293–297, 10.1016/j.ijmm.2013.02.004.
    • (2013) Int. J. Med. Microbiol. , vol.303 , pp. 293-297
    • Rojas, A.R.1    Beltrán, J.R.2    Couce, A.3    Blázquez, J.4
  • 242
    • 77956055569 scopus 로고    scopus 로고
    • Advanced monitoring of pharmaceuticals and estrogens in the Llobregat River Basin (Spain) by liquid chromatography-triple quadrupole-tandem mass spectrometry in combination with ultra performance liquid chromatography-time of flight-mass spectrometry
    • Roldán, R.L., Alda, M.L., Gros, M., et al. Advanced monitoring of pharmaceuticals and estrogens in the Llobregat River Basin (Spain) by liquid chromatography-triple quadrupole-tandem mass spectrometry in combination with ultra performance liquid chromatography-time of flight-mass spectrometry. Chemosphere 80 (2010), 1337–1344, 10.1016/j.chemosphere.2010.06.042.
    • (2010) Chemosphere , vol.80 , pp. 1337-1344
    • Roldán, R.L.1    Alda, M.L.2    Gros, M.3
  • 243
    • 75849133604 scopus 로고    scopus 로고
    • Occurrence of emerging pollutants in urban wastewater and their removal through biological treatment followed by ozonation
    • Rosal, R., Rodríguez, A., Melón, J.A.P., et al. Occurrence of emerging pollutants in urban wastewater and their removal through biological treatment followed by ozonation. Water Res. 44 (2010), 578–588, 10.1016/j.watres.2009.07.004.
    • (2010) Water Res. , vol.44 , pp. 578-588
    • Rosal, R.1    Rodríguez, A.2    Melón, J.A.P.3
  • 244
    • 84906655226 scopus 로고    scopus 로고
    • Simultaneous determination of most prescribed antibiotics in multiple urban wastewater by SPE-LC-MS/MS
    • Rossmann, J., Schubert, S., Gurke, R., et al. Simultaneous determination of most prescribed antibiotics in multiple urban wastewater by SPE-LC-MS/MS. J. Chromatogr. B 969 (2014), 162–170, 10.1016/j.jchromb.2014.08.008.
    • (2014) J. Chromatogr. B , vol.969 , pp. 162-170
    • Rossmann, J.1    Schubert, S.2    Gurke, R.3
  • 245
    • 84942100251 scopus 로고    scopus 로고
    • Quantitative target and systematic non-target analysis of polar organic micro-pollutants along the river Rhine using high-resolution mass-spectrometry – identification of unknown sources and compounds
    • Ruff, M., Mueller, M.S., Loos, M., Singer, H.P., Quantitative target and systematic non-target analysis of polar organic micro-pollutants along the river Rhine using high-resolution mass-spectrometry – identification of unknown sources and compounds. Water Res. 87 (2015), 145–154, 10.1016/j.watres.2015.09.017.
    • (2015) Water Res. , vol.87 , pp. 145-154
    • Ruff, M.1    Mueller, M.S.2    Loos, M.3    Singer, H.P.4
  • 246
    • 66649103438 scopus 로고    scopus 로고
    • Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste
    • Sanford, J.C.C., Mackie, R.I., Koike, S., et al. Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste. J. Environ. Qual. 38 (2009), 1086–1108, 10.2134/jeq2008.0128.
    • (2009) J. Environ. Qual. , vol.38 , pp. 1086-1108
    • Sanford, J.C.C.1    Mackie, R.I.2    Koike, S.3
  • 247
    • 84878908692 scopus 로고    scopus 로고
    • Contribution of hospital effluents to the load of pharmaceuticals in urban wastewaters: identification of ecologically relevant pharmaceuticals
    • Santos, L.H.M.L.M., Gros, M., Mozaz, S.R., et al. Contribution of hospital effluents to the load of pharmaceuticals in urban wastewaters: identification of ecologically relevant pharmaceuticals. Sci. Total Environ. 461-462 (2013), 302–316, 10.1016/j.scitotenv.2013.04.077.
    • (2013) Sci. Total Environ. , vol.461-462 , pp. 302-316
    • Santos, L.H.M.L.M.1    Gros, M.2    Mozaz, S.R.3
  • 248
    • 33747876745 scopus 로고    scopus 로고
    • A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment
    • Sarmah, A.K., Meyer, M.T., Boxall, A.B.A., A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. Chemosphere 65 (2006), 725–759, 10.1016/j.chemosphere.2006.03.026.
    • (2006) Chemosphere , vol.65 , pp. 725-759
    • Sarmah, A.K.1    Meyer, M.T.2    Boxall, A.B.A.3
  • 249
    • 84894649558 scopus 로고    scopus 로고
    • A review of what is an emerging contaminant
    • Sauvé, S., Desrosiers, M., A review of what is an emerging contaminant. Chem. Cent. J 8 (2014), 1–8, 10.1186/1752-153X-8-15.
    • (2014) Chem. Cent. J , vol.8 , pp. 1-8
    • Sauvé, S.1    Desrosiers, M.2
  • 250
    • 79959709098 scopus 로고    scopus 로고
    • Communicable diseases: Achievements and challenges for public health
    • Schlipköter, U., Flahault, A., Communicable diseases: Achievements and challenges for public health. Public Health Rev. 32 (2010), 90–119.
    • (2010) Public Health Rev. , vol.32 , pp. 90-119
    • Schlipköter, U.1    Flahault, A.2
  • 251
    • 68749086038 scopus 로고    scopus 로고
    • An overview of analytical methodologies for the determination of antibiotics in environmental waters
    • Seifrtová, M., Nováková, L., Lino, C., et al. An overview of analytical methodologies for the determination of antibiotics in environmental waters. Anal. Chim. Acta 649 (2009), 158–179, 10.1016/j.aca.2009.07.031.
    • (2009) Anal. Chim. Acta , vol.649 , pp. 158-179
    • Seifrtová, M.1    Nováková, L.2    Lino, C.3
  • 252
    • 77954997263 scopus 로고    scopus 로고
    • Determination of fluoroquinolone antibiotics in wastewater using ultra high-performance liquid chromatography with mass spectrometry and fluorescence detection
    • Seifrtová, M., Aufartová, J., Vytlacilová, J., et al. Determination of fluoroquinolone antibiotics in wastewater using ultra high-performance liquid chromatography with mass spectrometry and fluorescence detection. J. Sep. Sci. 33 (2010), 2094–2108, 10.1002/jssc.201000215.
    • (2010) J. Sep. Sci. , vol.33 , pp. 2094-2108
    • Seifrtová, M.1    Aufartová, J.2    Vytlacilová, J.3
  • 253
    • 84871525003 scopus 로고    scopus 로고
    • Occurrence and fate of dissolved and particulate antimicrobials in municipal wastewater treatment
    • Senta, I., Terzic, S., Ahel, M., Occurrence and fate of dissolved and particulate antimicrobials in municipal wastewater treatment. Water Res. 47 (2013), 705–714, 10.1016/j.watres.2012.10.041.
    • (2013) Water Res. , vol.47 , pp. 705-714
    • Senta, I.1    Terzic, S.2    Ahel, M.3
  • 254
    • 78650028791 scopus 로고    scopus 로고
    • Fully automated determination of 74 pharmaceuticals in environmental and waste waters by online solid phase extraction–liquid chromatography-electrospray–tandem mass spectrometry
    • Serna, R.L., Pérez, S., Ginebreda, A., et al. Fully automated determination of 74 pharmaceuticals in environmental and waste waters by online solid phase extraction–liquid chromatography-electrospray–tandem mass spectrometry. Talanta 83 (2010), 410–424, 10.1016/j.talanta.2010.09.046.
    • (2010) Talanta , vol.83 , pp. 410-424
    • Serna, R.L.1    Pérez, S.2    Ginebreda, A.3
  • 255
    • 82455171922 scopus 로고    scopus 로고
    • Development of a fast instrumental method for the analysis of pharmaceuticals in environmental and wastewaters based on ultra high performance liquid chromatography (UHPLC)-tandem mass spectrometry (MS/MS)
    • Serna, R.L., Petrović, M., Barceló, D., Development of a fast instrumental method for the analysis of pharmaceuticals in environmental and wastewaters based on ultra high performance liquid chromatography (UHPLC)-tandem mass spectrometry (MS/MS). Chemosphere 85 (2011), 1390–1399, 10.1016/j.chemosphere.2011.07.071.
    • (2011) Chemosphere , vol.85 , pp. 1390-1399
    • Serna, R.L.1    Petrović, M.2    Barceló, D.3
  • 256
    • 84868697022 scopus 로고    scopus 로고
    • Occurrence and distribution of multi-class pharmaceuticals and their active metabolites and transformation products in the Ebro river basin (NE Spain)
    • Serna, R.L., Petrović, M., Barceló, D., Occurrence and distribution of multi-class pharmaceuticals and their active metabolites and transformation products in the Ebro river basin (NE Spain). Sci. Total Environ. 440 (2012), 280–289, 10.1016/j.scitotenv.2012.06.027.
    • (2012) Sci. Total Environ. , vol.440 , pp. 280-289
    • Serna, R.L.1    Petrović, M.2    Barceló, D.3
  • 257
    • 58349114445 scopus 로고    scopus 로고
    • Carrier mediated hollow fiber liquid phase microextraction combined with HPLC-UV for preconcentration and determination of some tetracycline antibiotics
    • Shariati, S., Yamini, Y., Esrafili, A., Carrier mediated hollow fiber liquid phase microextraction combined with HPLC-UV for preconcentration and determination of some tetracycline antibiotics. J. Chromatogr. B 877 (2009), 393–400, 10.1016/j.jchromb.2008.12.042.
    • (2009) J. Chromatogr. B , vol.877 , pp. 393-400
    • Shariati, S.1    Yamini, Y.2    Esrafili, A.3
  • 258
    • 84919742485 scopus 로고    scopus 로고
    • Liquid chromatography-tandem mass spectrometry multiclass method for the determination of antibiotics residues in water samples from water supply systems in food-producing animal farms
    • Sikorska, M.G., Posyniak, A., Sniegocki, T., Zmudzki, J., Liquid chromatography-tandem mass spectrometry multiclass method for the determination of antibiotics residues in water samples from water supply systems in food-producing animal farms. Chemosphere 119 (2015), 8–15, 10.1016/j.chemosphere.2014.04.105.
    • (2015) Chemosphere , vol.119 , pp. 8-15
    • Sikorska, M.G.1    Posyniak, A.2    Sniegocki, T.3    Zmudzki, J.4
  • 259
    • 82455199111 scopus 로고    scopus 로고
    • Occurrence and distribution of pharmaceuticals in surface water, suspended solids and sediments of the Ebro river basin, Spain
    • Silva, B.F., Jelic, A., Serna, R.L., et al. Occurrence and distribution of pharmaceuticals in surface water, suspended solids and sediments of the Ebro river basin, Spain. Chemosphere 85 (2011), 1331–1339, 10.1016/j.chemosphere.2011.07.051.
    • (2011) Chemosphere , vol.85 , pp. 1331-1339
    • Silva, B.F.1    Jelic, A.2    Serna, R.L.3
  • 260
    • 84947710716 scopus 로고    scopus 로고
    • Fractionation and analysis of veterinary antibiotics and their related degradation products in agricultural soils and drainage waters following swine manure amendment
    • Solliec, M., Lachapelle, A.R., Gasser, M.O., et al. Fractionation and analysis of veterinary antibiotics and their related degradation products in agricultural soils and drainage waters following swine manure amendment. Sci. Total Environ. 543 (2016), 524–535, 10.1016/j.scitotenv.2015.11.061.
    • (2016) Sci. Total Environ. , vol.543 , pp. 524-535
    • Solliec, M.1    Lachapelle, A.R.2    Gasser, M.O.3
  • 261
    • 0031986456 scopus 로고    scopus 로고
    • Occurrence, fate and effects of pharmaceutical substances in the environment: A review
    • Sørensen, B.H., Nielsen, S.N., Lanzky, P.F., et al. Occurrence, fate and effects of pharmaceutical substances in the environment: A review. Chemosphere 36 (1998), 357–393, 10.1016/S0045-6535(97)00354-8.
    • (1998) Chemosphere , vol.36 , pp. 357-393
    • Sørensen, B.H.1    Nielsen, S.N.2    Lanzky, P.F.3
  • 262
    • 39449103059 scopus 로고    scopus 로고
    • The epidemic of antibiotic-resistant infections: A call to action for the medical community from the Infectious Diseases Society of America
    • Spellberg, B., Guidos, R., Gilbert, D., et al. The epidemic of antibiotic-resistant infections: A call to action for the medical community from the Infectious Diseases Society of America. Clin. Infect. Dis. 46 (2008), 155–164, 10.1086/524891.
    • (2008) Clin. Infect. Dis. , vol.46 , pp. 155-164
    • Spellberg, B.1    Guidos, R.2    Gilbert, D.3
  • 264
    • 84856232961 scopus 로고    scopus 로고
    • Review of risk from potential emerging contaminants in UK groundwater
    • Stuart, M., Lapworth, D., Crane, E., Hart, A., Review of risk from potential emerging contaminants in UK groundwater. Sci. Total Environ. 416 (2012), 1–21, 10.1016/j.scitotenv.2011.11.072.
    • (2012) Sci. Total Environ. , vol.416 , pp. 1-21
    • Stuart, M.1    Lapworth, D.2    Crane, E.3    Hart, A.4
  • 265
    • 84960416632 scopus 로고    scopus 로고
    • Biodegradation of sulfamethoxazole photo-transformation products in a water/sediment test
    • Su, T., Deng, H., Benskin, J.P., Radke, M., Biodegradation of sulfamethoxazole photo-transformation products in a water/sediment test. Chemosphere 148 (2016), 518–525, 10.1016/j.chemosphere.2016.01.049.
    • (2016) Chemosphere , vol.148 , pp. 518-525
    • Su, T.1    Deng, H.2    Benskin, J.P.3    Radke, M.4
  • 266
    • 84928753191 scopus 로고    scopus 로고
    • Selective pressurized liquid extraction as a sample preparation technique for persistent organic pollutants and contaminants of emerging concern
    • Subedi, B., Aguilar, L., Robinson, E.M., et al. Selective pressurized liquid extraction as a sample preparation technique for persistent organic pollutants and contaminants of emerging concern. TrAC Trends Anal. Chem. 68 (2015), 119–132, 10.1016/j.trac.2015.02.011.
    • (2015) TrAC Trends Anal. Chem. , vol.68 , pp. 119-132
    • Subedi, B.1    Aguilar, L.2    Robinson, E.M.3
  • 267
    • 39149128241 scopus 로고    scopus 로고
    • Occurrence and fate of antibiotics in the Seine River in various hydrological conditions
    • Tamtam, F., Mercier, F., Le Bot, B., et al. Occurrence and fate of antibiotics in the Seine River in various hydrological conditions. Sci. Total Environ. 393 (2008), 84–95, 10.1016/j.scitotenv.2007.12.009.
    • (2008) Sci. Total Environ. , vol.393 , pp. 84-95
    • Tamtam, F.1    Mercier, F.2    Le Bot, B.3
  • 268
    • 54349105912 scopus 로고    scopus 로고
    • Fast screening procedure for antibiotics in wastewaters by direct HPLC-DAD analysis
    • Teixeira, S., Matos, C.D., Alves, A., Santos, L., Fast screening procedure for antibiotics in wastewaters by direct HPLC-DAD analysis. J. Sep. Sci. 31 (2008), 2924–2931, 10.1002/jssc.200800229.
    • (2008) J. Sep. Sci. , vol.31 , pp. 2924-2931
    • Teixeira, S.1    Matos, C.D.2    Alves, A.3    Santos, L.4
  • 270
    • 0034892129 scopus 로고    scopus 로고
    • Analytical methods for the determination of pharmaceuticals in aqueous environmental samples
    • Ternes, T.A., Analytical methods for the determination of pharmaceuticals in aqueous environmental samples. TrAC Trends Anal. Chem. 20 (2001), 419–434, 10.1016/S0165-9936(01)00078-4.
    • (2001) TrAC Trends Anal. Chem. , vol.20 , pp. 419-434
    • Ternes, T.A.1
  • 271
    • 84926326169 scopus 로고    scopus 로고
    • Occurrence, fate, removal and assessment of emerging contaminants in water in the water cycle (from wastewater to drinking water)
    • Ternes, T., Joss, A., Oehlmann, J., Occurrence, fate, removal and assessment of emerging contaminants in water in the water cycle (from wastewater to drinking water). Water Res. 72 (2015), 1–2, 10.1016/j.watres.2015.02.055.
    • (2015) Water Res. , vol.72 , pp. 1-2
    • Ternes, T.1    Joss, A.2    Oehlmann, J.3
  • 272
    • 44749087182 scopus 로고    scopus 로고
    • Occurrence and fate of emerging wastewater contaminants in Western Balkan Region
    • Terzić, S., Senta, I., Ahel, M., et al. Occurrence and fate of emerging wastewater contaminants in Western Balkan Region. Sci. Total Environ. 399 (2008), 66–77, 10.1016/j.scitotenv.2008.03.003.
    • (2008) Sci. Total Environ. , vol.399 , pp. 66-77
    • Terzić, S.1    Senta, I.2    Ahel, M.3
  • 273
    • 8444234972 scopus 로고    scopus 로고
    • The occurrence of selected human pharmaceutical compounds in UK estuaries
    • Thomas, K.V., Hilton, M.J., The occurrence of selected human pharmaceutical compounds in UK estuaries. Mar. Pollut. Bull. 49 (2004), 436–444, 10.1016/j.marpolbul.2004.02.028.
    • (2004) Mar. Pollut. Bull. , vol.49 , pp. 436-444
    • Thomas, K.V.1    Hilton, M.J.2
  • 274
    • 84905739143 scopus 로고    scopus 로고
    • Occurrence of antibiotics in the aquatic environment of Jianghan Plain, central China
    • Tong, L., Huang, S., Wang, Y., et al. Occurrence of antibiotics in the aquatic environment of Jianghan Plain, central China. Sci. Total Environ. 497-498 (2014), 180–187, 10.1016/j.scitotenv.2014.07.068.
    • (2014) Sci. Total Environ. , vol.497-498 , pp. 180-187
    • Tong, L.1    Huang, S.2    Wang, Y.3
  • 275
    • 84961689476 scopus 로고    scopus 로고
    • Initial hazard screening for genotoxicity of photo-transformation products of ciprofloxacin by applying a combination of experimental and in-silico testing
    • Toolaram, A.P., Haddad, T., Leder, C., Kümmerer, K., Initial hazard screening for genotoxicity of photo-transformation products of ciprofloxacin by applying a combination of experimental and in-silico testing. Environ. Pollut. 211 (2016), 148–156, 10.1016/j.envpol.2015.12.040.
    • (2016) Environ. Pollut. , vol.211 , pp. 148-156
    • Toolaram, A.P.1    Haddad, T.2    Leder, C.3    Kümmerer, K.4
  • 276
    • 60649119989 scopus 로고    scopus 로고
    • Dispersive solid-phase microextraction method for sample extraction in the analysis of four tetracyclines in water and milk samples by high-performance liquid chromatography with diode-array detection
    • Tsai, W.H., Huang, T.C., Huang, J.J., et al. Dispersive solid-phase microextraction method for sample extraction in the analysis of four tetracyclines in water and milk samples by high-performance liquid chromatography with diode-array detection. J. Chromatogr. A 1216 (2009), 2263–2269, 10.1016/j.chroma.2009.01.034.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 2263-2269
    • Tsai, W.H.1    Huang, T.C.2    Huang, J.J.3
  • 277
    • 84879508507 scopus 로고    scopus 로고
    • Determination of antibiotics in influents and effluents of wastewater-treatment-plants in the Czech Republic-development and application of the SPE and a UHPLC-ToFMS method
    • Tylová, T., Flieger, M., Olšovská, J., Determination of antibiotics in influents and effluents of wastewater-treatment-plants in the Czech Republic-development and application of the SPE and a UHPLC-ToFMS method. Anal. Methods 5 (2013), 2110–2118, 10.1039/c3ay00048f.
    • (2013) Anal. Methods , vol.5 , pp. 2110-2118
    • Tylová, T.1    Flieger, M.2    Olšovská, J.3
  • 278
    • 84989293123 scopus 로고    scopus 로고
    • Contaminants of Emerging Concern
    • US EPA, Contaminants of Emerging Concern. 2014.
    • (2014)
    • US EPA1
  • 279
    • 79961206836 scopus 로고    scopus 로고
    • Detection of pharmaceutically active compounds in the rivers and tap water of the Madrid Region (Spain) and potential ecotoxicological risk
    • Valcárcel, Y., Alonso, S.G., Gil, J.L.R., et al. Detection of pharmaceutically active compounds in the rivers and tap water of the Madrid Region (Spain) and potential ecotoxicological risk. Chemosphere 84 (2011), 1336–1348, 10.1016/j.chemosphere.2011.05.014.
    • (2011) Chemosphere , vol.84 , pp. 1336-1348
    • Valcárcel, Y.1    Alonso, S.G.2    Gil, J.L.R.3
  • 280
    • 84922693681 scopus 로고    scopus 로고
    • Multiresidue analysis of pharmaceuticals in wastewater by liquid chromatography-magnetic sector mass spectrometry: Method quality assessment and application in a Belgian case study
    • Vergeynst, L., Haeck, A., Wispelaere, P., et al. Multiresidue analysis of pharmaceuticals in wastewater by liquid chromatography-magnetic sector mass spectrometry: Method quality assessment and application in a Belgian case study. Chemosphere 119 (2015), S2–S8, 10.1016/j.chemosphere.2014.03.069.
    • (2015) Chemosphere , vol.119 , pp. S2-S8
    • Vergeynst, L.1    Haeck, A.2    Wispelaere, P.3
  • 281
    • 84861332141 scopus 로고    scopus 로고
    • Hospital effluent: Investigation of the concentrations and distribution of pharmaceuticals and environmental risk assessment
    • Verlicchi, P., Al Aukidy, M., Galletti, A., et al. Hospital effluent: Investigation of the concentrations and distribution of pharmaceuticals and environmental risk assessment. Sci. Total Environ. 430 (2012), 109–118, 10.1016/j.scitotenv.2012.04.055.
    • (2012) Sci. Total Environ. , vol.430 , pp. 109-118
    • Verlicchi, P.1    Al Aukidy, M.2    Galletti, A.3
  • 282
    • 84887149392 scopus 로고    scopus 로고
    • Comparison of measured and predicted concentrations of selected pharmaceuticals in wastewater and surface water: A case study of a catchment area in the Po Valley (Italy)
    • Verlicchi, P., Al Aukidy, M., Jelic, A., et al. Comparison of measured and predicted concentrations of selected pharmaceuticals in wastewater and surface water: A case study of a catchment area in the Po Valley (Italy). Sci. Total Environ. 470-471 (2014), 844–854, 10.1016/j.scitotenv.2013.10.026.
    • (2014) Sci. Total Environ. , vol.470-471 , pp. 844-854
    • Verlicchi, P.1    Al Aukidy, M.2    Jelic, A.3
  • 283
    • 33750362141 scopus 로고    scopus 로고
    • Analysis of neutral and basic pharmaceuticals in sewage treatment plants and in recipient rivers using solid phase extraction and liquid chromatography-tandem mass spectrometry detection
    • Vieno, N.M., Tuhkanen, T., Kronberg, L., Analysis of neutral and basic pharmaceuticals in sewage treatment plants and in recipient rivers using solid phase extraction and liquid chromatography-tandem mass spectrometry detection. J. Chromatogr. A 1134 (2006), 101–111, 10.1016/j.chroma.2006.08.077.
    • (2006) J. Chromatogr. A , vol.1134 , pp. 101-111
    • Vieno, N.M.1    Tuhkanen, T.2    Kronberg, L.3
  • 284
    • 34547143730 scopus 로고    scopus 로고
    • Occurrence of pharmaceuticals in river water and their elimination in a pilot-scale drinking water treatment plant
    • Vieno, N.M., Härkki, H., Tuhkanen, T., Kronberg, L., Occurrence of pharmaceuticals in river water and their elimination in a pilot-scale drinking water treatment plant. Environ. Sci. Technol. 41 (2007), 5077–5084, 10.1021/es062720x.
    • (2007) Environ. Sci. Technol. , vol.41 , pp. 5077-5084
    • Vieno, N.M.1    Härkki, H.2    Tuhkanen, T.3    Kronberg, L.4
  • 285
    • 33846818656 scopus 로고    scopus 로고
    • Elimination of pharmaceuticals in sewage treatment plants in Finland
    • Vieno, N.M., Tuhkanen, T., Kronberg, L., Elimination of pharmaceuticals in sewage treatment plants in Finland. Water Res. 41 (2007), 1001–1012, 10.1016/j.watres.2006.12.017.
    • (2007) Water Res. , vol.41 , pp. 1001-1012
    • Vieno, N.M.1    Tuhkanen, T.2    Kronberg, L.3
  • 286
    • 84904367804 scopus 로고    scopus 로고
    • Development of sensitive and reliable LC-MS/MS methods for the determination of three fluoroquinolones in water and fish tissue samples and preliminary environmental risk assessment of their presence in two rivers in northern Poland
    • Wagil, M., Kumirska, J., Stolte, S., et al. Development of sensitive and reliable LC-MS/MS methods for the determination of three fluoroquinolones in water and fish tissue samples and preliminary environmental risk assessment of their presence in two rivers in northern Poland. Sci. Total Environ. 493 (2014), 1006–1013, 10.1016/j.scitotenv.2014.06.082.
    • (2014) Sci. Total Environ. , vol.493 , pp. 1006-1013
    • Wagil, M.1    Kumirska, J.2    Stolte, S.3
  • 287
    • 84922704744 scopus 로고    scopus 로고
    • Determination of metronidazole residues in water, sediment and fish tissue samples
    • Wagil, M., Maszkowska, J., Białk-Bielińska, A., et al. Determination of metronidazole residues in water, sediment and fish tissue samples. Chemosphere 119 (2015), S28–S34, 10.1016/j.chemosphere.2013.12.061.
    • (2015) Chemosphere , vol.119 , pp. S28-S34
    • Wagil, M.1    Maszkowska, J.2    Białk-Bielińska, A.3
  • 288
    • 34548687233 scopus 로고    scopus 로고
    • Removal of antibiotics in conventional and advanced wastewater treatment: Implications for environmental discharge and wastewater recycling
    • Watkinson, A.J., Murby, E.J., Costanzo, S.D., Removal of antibiotics in conventional and advanced wastewater treatment: Implications for environmental discharge and wastewater recycling. Water Res. 41 (2007), 4164–4176, 10.1016/j.watres.2007.04.005.
    • (2007) Water Res. , vol.41 , pp. 4164-4176
    • Watkinson, A.J.1    Murby, E.J.2    Costanzo, S.D.3
  • 289
    • 84863985794 scopus 로고    scopus 로고
    • Tackling antibiotic resistance from a food safety perspective in Europe
    • (Copenhagen)
    • WHO, Tackling antibiotic resistance from a food safety perspective in Europe. 2011 (Copenhagen).
    • (2011)
    • WHO1
  • 290
    • 84859699016 scopus 로고    scopus 로고
    • The evolving threat of antimicrobial resistance: Options for action
    • (Geneva)
    • WHO, The evolving threat of antimicrobial resistance: Options for action. 2012 (Geneva).
    • (2012)
    • WHO1
  • 291
    • 84965040841 scopus 로고    scopus 로고
    • Antimicrobial resistance: Global report on surveillance
    • (Geneva)
    • WHO, Antimicrobial resistance: Global report on surveillance. 2014 (Geneva).
    • (2014)
    • WHO1
  • 292
    • 84956624292 scopus 로고    scopus 로고
    • Worldwide country situation analysis: Response to antimicrobial resistance
    • (Geneva)
    • WHO, Worldwide country situation analysis: Response to antimicrobial resistance. 2015 (Geneva).
    • (2015)
    • WHO1
  • 293
  • 294
    • 35348977720 scopus 로고    scopus 로고
    • Occurrence and elimination of antibiotics at four sewage treatment plants in the Pearl River Delta (PRD), South China
    • Xu, W., Zhang, G., Li, X., et al. Occurrence and elimination of antibiotics at four sewage treatment plants in the Pearl River Delta (PRD), South China. Water Res. 41 (2007), 4526–4534, 10.1016/j.watres.2007.06.023.
    • (2007) Water Res. , vol.41 , pp. 4526-4534
    • Xu, W.1    Zhang, G.2    Li, X.3
  • 295
    • 84919848520 scopus 로고    scopus 로고
    • Occurrence of antibiotics and antibiotic resistance genes in a sewage treatment plant and its effluent-receiving river
    • Xu, J., Xu, Y., Wang, H., et al. Occurrence of antibiotics and antibiotic resistance genes in a sewage treatment plant and its effluent-receiving river. Chemosphere 119 (2015), 1379–1385, 10.1016/j.chemosphere.2014.02.040.
    • (2015) Chemosphere , vol.119 , pp. 1379-1385
    • Xu, J.1    Xu, Y.2    Wang, H.3
  • 296
    • 34249707915 scopus 로고    scopus 로고
    • Simultaneous determination of various pharmaceutical compounds in water by solid-phase extraction-liquid chromatography-tandem mass spectrometry
    • Zhang, Z.L., Zhou, J.L., Simultaneous determination of various pharmaceutical compounds in water by solid-phase extraction-liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 1154 (2007), 205–213, 10.1016/j.chroma.2007.03.105.
    • (2007) J. Chromatogr. A , vol.1154 , pp. 205-213
    • Zhang, Z.L.1    Zhou, J.L.2
  • 297
    • 84938677371 scopus 로고    scopus 로고
    • Tissue-specific bioaccumulation of human and veterinary antibiotics in bile, plasma, liver and muscle tissues of wild fish from a highly urbanized region
    • Zhao, J.L., Liu, Y.S., Liu, W.R., et al. Tissue-specific bioaccumulation of human and veterinary antibiotics in bile, plasma, liver and muscle tissues of wild fish from a highly urbanized region. Environ. Pollut. 198 (2014), 15–24, 10.1016/j.envpol.2014.12.026.
    • (2014) Environ. Pollut. , vol.198 , pp. 15-24
    • Zhao, J.L.1    Liu, Y.S.2    Liu, W.R.3
  • 298
    • 61449251517 scopus 로고    scopus 로고
    • Occurrence and removal of pharmaceuticals in a municipal sewage treatment system in the south of Sweden
    • Zorita, S., Mårtensson, L., Mathiasson, L., Occurrence and removal of pharmaceuticals in a municipal sewage treatment system in the south of Sweden. Sci. Total Environ. 407 (2009), 2760–2770, 10.1016/j.scitotenv.2008.12.030.
    • (2009) Sci. Total Environ. , vol.407 , pp. 2760-2770
    • Zorita, S.1    Mårtensson, L.2    Mathiasson, L.3
  • 299
    • 20444446604 scopus 로고    scopus 로고
    • Identification of the pharmaceuticals for human use contaminating the Italian aquatic environment
    • Zuccato, E., Castiglioni, S., Fanelli, R., Identification of the pharmaceuticals for human use contaminating the Italian aquatic environment. J. Hazard. Mater. 122 (2005), 205–209, 10.1016/j.jhazmat.2005.03.001.
    • (2005) J. Hazard. Mater. , vol.122 , pp. 205-209
    • Zuccato, E.1    Castiglioni, S.2    Fanelli, R.3
  • 300
    • 77952890793 scopus 로고    scopus 로고
    • Source, occurrence and fate of antibiotics in the Italian aquatic environment
    • Zuccato, E., Castiglioni, S., Bagnati, R., et al. Source, occurrence and fate of antibiotics in the Italian aquatic environment. J. Hazard. Mater. 179 (2010), 1042–1048, 10.1016/j.jhazmat.2010.03.110.
    • (2010) J. Hazard. Mater. , vol.179 , pp. 1042-1048
    • Zuccato, E.1    Castiglioni, S.2    Bagnati, R.3
  • 301
    • 2942621834 scopus 로고    scopus 로고
    • LC-MS analysis in the aquatic environment and in water treatment technology - A critical review. Part II: Applications for emerging contaminants and related pollutants, microorganisms and humic acids
    • Zwiener, C., Frimmel, F.H., LC-MS analysis in the aquatic environment and in water treatment technology - A critical review. Part II: Applications for emerging contaminants and related pollutants, microorganisms and humic acids. Anal. Bioanal. Chem. 378 (2004), 862–874, 10.1007/s00216-003-2412-1.
    • (2004) Anal. Bioanal. Chem. , vol.378 , pp. 862-874
    • Zwiener, C.1    Frimmel, F.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.