Initial hazard screening for genotoxicity of photo-transformation products of ciprofloxacin by applying a combination of experimental and in-silico testing

Environmental Pollution

Volumn 211, Issue , 2016, Pages 148-156

  Toolaram, Anju Priya ^a   Haddad, Tarek ^a,b   Leder, Christoph ^a   Kümmerer, Klaus ^a  

^a LEUPHANA UNIVERSITY OF LÜNEBURG   (Germany)

^b UNIVERSITY OF ALEPPO   (Syrian Arab Republic)

Author keywords

Combination index analysis; Effect based analysis; Fluoroquinolones; UV photolysis; Whole mixture genotoxicity

Indexed keywords

ANTIBIOTICS; ASSAYS; COMPUTATIONAL CHEMISTRY; MAMMALS; MOLECULAR GRAPHICS; PHOTOLYSIS; TOXIC MATERIALS;

EFFECT BASED ANALYSIS; FLUOROQUINOLONES; GENOTOXICITIES; INDEX ANALYSIS; UV PHOTOLYSIS;

MIXTURES;

CIPROFLOXACIN; ANTIINFECTIVE AGENT; MUTAGENIC AGENT;

CONCENTRATION (COMPOSITION); GENOTOXICITY; PHOTOLYSIS; ULTRAVIOLET RADIATION; WASTE TREATMENT; WASTEWATER;

ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENVIRONMENTAL MONITORING; FEMALE; GENOTOXICITY; HAZARD; LIQUID CHROMATOGRAPHY; MUTAGENICITY; NONHUMAN; PHOTODEGRADATION; QUANTITATIVE ANALYSIS; STRUCTURE ACTIVITY RELATION; ANIMAL; CHEMISTRY; COMPUTER SIMULATION; DNA DAMAGE; MICRONUCLEUS TEST; PHOTOLYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; ULTRAVIOLET RADIATION;

BACTERIA (MICROORGANISMS); MAMMALIA;

ANIMALS; ANTI-BACTERIAL AGENTS; CIPROFLOXACIN; COMPUTER SIMULATION; DNA DAMAGE; MICRONUCLEUS TESTS; MUTAGENS; PHOTOLYSIS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; ULTRAVIOLET RAYS;

EID: 84961689476     PISSN: 02697491     EISSN: 18736424     Source Type: Journal    
DOI: 10.1016/j.envpol.2015.12.040     Document Type: Article

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