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Volumn 1, Issue DEC, 2010, Pages

A brief history of the antibiotic era: Lessons learned and challenges for the future

Author keywords

Antibiotic resistance; Environmental resistome; History of antibiotic discovery; Novel antimicrobials; Prevention of antibiotic resistance

Indexed keywords


EID: 79960399031     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2010.00134     Document Type: Article
Times cited : (913)

References (77)
  • 1
    • 0000123301 scopus 로고
    • An enzyme from bacteria able to destroy penicillin
    • Abraham, E. P., and Chain, E. (1940). An enzyme from bacteria able to destroy penicillin. Nature 146, 837.
    • (1940) Nature , vol.146 , pp. 837
    • Abraham, E.P.1    Chain, E.2
  • 2
    • 71249091793 scopus 로고    scopus 로고
    • The role of antibiotics and antibiotic resistance in nature
    • Aminov, R. I. (2009). The role of antibiotics and antibiotic resistance in nature. Environ. Microbiol. 11, 2970-2988.
    • (2009) Environ. Microbiol. , vol.11 , pp. 2970-2988
    • Aminov, R.I.1
  • 3
    • 34249076303 scopus 로고    scopus 로고
    • Evolution and ecology of antibiotic resistance genes
    • Aminov, R. I., and Mackie, R. I. (2007). Evolution and ecology of antibiotic resistance genes. FEMS Microbiol. Lett. 271, 147-161.
    • (2007) FEMS Microbiol. Lett. , vol.271 , pp. 147-161
    • Aminov, R.I.1    Mackie, R.I.2
  • 4
    • 0014681770 scopus 로고
    • Disease in ancient Nubia
    • Armelagos, G. J. (1969). Disease in ancient Nubia. Science 163, 225-258.
    • (1969) Science , vol.163 , pp. 225-258
    • Armelagos, G.J.1
  • 5
    • 0019333691 scopus 로고
    • Tetracycline-labeled human bone from ancient Sudanese Nubia (A.D. 350)
    • Bassett, E. J., Keith, M. S., Armelagos, G. J., Martin, D. L., and Villanueva, A. R. (1980). Tetracycline-labeled human bone from ancient Sudanese Nubia (A.D. 350). Science 209, 1532-1534.
    • (1980) Science , vol.209 , pp. 1532-1534
    • Bassett, E.J.1    Keith, M.S.2    Armelagos, G.J.3    Martin, D.L.4    Villanueva, A.R.5
  • 6
    • 0345827436 scopus 로고    scopus 로고
    • SOS response promotes horizontal dissemination of antibiotic resistance genes
    • Beaber, J. W., Hochhut, B., and Waldor M. K. (2004). SOS response promotes horizontal dissemination of antibiotic resistance genes. Nature 427, 72-74.
    • (2004) Nature , vol.427 , pp. 72-74
    • Beaber, J.W.1    Hochhut, B.2    Waldor, M.K.3
  • 7
    • 33751540952 scopus 로고    scopus 로고
    • Ant imicrobial resistance in Scandinavia after ban of antimicrobial growth promoters
    • Bengtsson, B., and Wierup, M. (2006). Ant imicrobial resistance in Scandinavia after ban of antimicrobial growth promoters. Anim. Biotechnol. 17, 147-156.
    • (2006) Anim. Biotechnol. , vol.17 , pp. 147-156
    • Bengtsson, B.1    Wierup, M.2
  • 8
    • 77956666195 scopus 로고    scopus 로고
    • New β-lactam antibiotics and β-lactamase inhibitors
    • Bush, K., and Macielag, M. J. (2010). New β-lactam antibiotics and β-lactamase inhibitors. Expert Opin. Ther. Pat. 20, 1277-1293.
    • (2010) Expert Opin. Ther. Pat. , vol.20 , pp. 1277-1293
    • Bush, K.1    Macielag, M.J.2
  • 9
    • 2442477676 scopus 로고    scopus 로고
    • A novel β-lactamase activity from a penicillin-binding protein of Treponema pallidum and why syphilis is still treatable with penicillin
    • Cha, J. Y., Ishiwata, A., and Mobashery, S. (2004). A novel β-lactamase activity from a penicillin-binding protein of Treponema pallidum and why syphilis is still treatable with penicillin. J. Biol. Chem. 279, 14917-14921.
    • (2004) J. Biol. Chem. , vol.279 , pp. 14917-14921
    • Cha, J.Y.1    Ishiwata, A.2    Mobashery, S.3
  • 12
    • 0242648263 scopus 로고    scopus 로고
    • Discovery and development of new anti-bacterial drugs
    • Trends in Drug Research III, ed. H. van der Goot (Amsterdam: Elsevier)
    • Chopra, I., Hesse, L., and O'Neill, A. (2002). "Discovery and development of new anti-bacterial drugs," in Pharmacochemistry Library, Vol. 32, Trends in Drug Research III, ed. H. van der Goot (Amsterdam: Elsevier), 213-225.
    • (2002) Pharmacochemistry Library , vol.32 , pp. 213-225
    • Chopra, I.1    Hesse, L.2    O'Neill, A.3
  • 13
    • 34548108138 scopus 로고    scopus 로고
    • Targeting virulence: a new paradigm for antimicrobial therapy
    • Clatworthy, A. E., Pierson, E., and Hung, D. T. (2007). Targeting virulence: a new paradigm for antimicrobial therapy. Nat. Chem. Biol. 3, 541-548.
    • (2007) Nat. Chem. Biol. , vol.3 , pp. 541-548
    • Clatworthy, A.E.1    Pierson, E.2    Hung, D.T.3
  • 14
    • 0024430703 scopus 로고
    • Fluorochrome labelling in Roman period skeletons from Dakhleh Oasis, Egypt
    • Cook, M., Molto, E., and Anderson, C. (1989). Fluorochrome labelling in Roman period skeletons from Dakhleh Oasis, Egypt. Am. J. Phys. Anthropol. 80, 137-143.
    • (1989) Am. J. Phys. Anthropol. , vol.80 , pp. 137-143
    • Cook, M.1    Molto, E.2    Anderson, C.3
  • 15
    • 70350616263 scopus 로고    scopus 로고
    • Discovery, mechanisms of action andcombination therapy of artemisinin
    • Cui, L., and Su, X. Z. (2009). Discovery, mechanisms of action andcombination therapy of artemisinin. Expert Rev. Anti. Infect. Ther. 7, 999-1013.
    • (2009) Expert Rev. Anti. Infect. Ther. , vol.7 , pp. 999-1013
    • Cui, L.1    Su, X.Z.2
  • 16
    • 33748698411 scopus 로고    scopus 로고
    • The world of subinhibitory antibiotic concentrations
    • Davies, J., Spiegelman, G. B., and Yim, G. (2006). The world of subinhibitory antibiotic concentrations. Curr. Opin. Microbiol. 9, 445-453.
    • (2006) Curr. Opin. Microbiol. , vol.9 , pp. 445-453
    • Davies, J.1    Spiegelman, G.B.2    Yim, G.3
  • 17
    • 34247892449 scopus 로고    scopus 로고
    • Gene and cell survival: lessons from prokaryotic plasmid R1
    • de la Cueva-Méndez, G., and Pimentel, B. (2007). Gene and cell survival: lessons from prokaryotic plasmid R1. EMBO Rep. 8, 458-464.
    • (2007) EMBO Rep , vol.8 , pp. 458-464
    • de la Cueva-Méndez, G.1    Pimentel, B.2
  • 19
    • 66649090346 scopus 로고    scopus 로고
    • The diarylquinoline TMC207 for multidrug-resistant tuberculosis
    • Diacon, A. H., Pym, A., and Grobusch, M. (2009). The diarylquinoline TMC207 for multidrug-resistant tuberculosis. N. Engl. J. Med. 360, 2397-2405.
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2397-2405
    • Diacon, A.H.1    Pym, A.2    Grobusch, M.3
  • 20
    • 0242628703 scopus 로고
    • Ein Beitrag zur Chemotherapie der bakteriellen Infektionen
    • Domagk, G. (1935). Ein Beitrag zur Chemotherapie der bakteriellen Infektionen. Dtsch. Med. Wochenschr. 61, 250.
    • (1935) Dtsch. Med. Wochenschr. , vol.61 , pp. 250
    • Domagk, G.1
  • 21
    • 49849090152 scopus 로고    scopus 로고
    • Quorum sensing by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species
    • Dubern, J. F., and Diggle, S. P. (2008). Quorum sensing by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species. Mol Biosyst 4, 882-888.
    • (2008) Mol Biosyst , vol.4 , pp. 882-888
    • Dubern, J.F.1    Diggle, S.P.2
  • 23
    • 0005711332 scopus 로고
    • Bakteriolytische enzyme als Ursache der erworbenen Immunität und die Heilung von Infectionskrankheiten durch dieselben
    • Emmerich, R., and Löw, O. (1899). Bakteriolytische enzyme als Ursache der erworbenen Immunität und die Heilung von Infectionskrankheiten durch dieselben. Z. Hyg. 31, 1-65.
    • (1899) Z. Hyg. , vol.31 , pp. 1-65
    • Emmerich, R.1    Löw, O.2
  • 24
    • 3042692238 scopus 로고    scopus 로고
    • Enhancement of host fitness by the sul2-coding plasmid p9123 in the absence of selective pressure
    • Enne, V. I., Bennett, P. M., Livermore, D. M., and Hall, L. M. (2004). Enhancement of host fitness by the sul2-coding plasmid p9123 in the absence of selective pressure. J. Antimicrob. Chemother. 53, 958-963.
    • (2004) J. Antimicrob. Chemother. , vol.53 , pp. 958-963
    • Enne, V.I.1    Bennett, P.M.2    Livermore, D.M.3    Hall, L.M.4
  • 26
    • 42049120716 scopus 로고    scopus 로고
    • Antibiotics as signals that trigger specific bacterial responses
    • Fajardo, A., and Martínez, J. L. (2008). Antibiotics as signals that trigger specific bacterial responses. Curr. Opin. Microbiol. 11, 161-167.
    • (2008) Curr. Opin. Microbiol. , vol.11 , pp. 161-167
    • Fajardo, A.1    Martínez, J.L.2
  • 27
    • 65549086033 scopus 로고    scopus 로고
    • Proliferation of antibiotic-producing bacteria and concomitant antibiotic production as the basis for the antibiotic activity of Jordan's red soils
    • Falkinham, J. O. 3rd, Wall, T. E., Tanner, J. R., Tawaha, K., Alali, F. Q., Li, C., and Oberlies, N. H. (2009). Proliferation of antibiotic-producing bacteria and concomitant antibiotic production as the basis for the antibiotic activity of Jordan's red soils. Appl. Environ. Microbiol. 75, 2735-2741.
    • (2009) Appl. Environ. Microbiol. , vol.75 , pp. 2735-2741
    • Falkinham III, J.O.1    Wall, T.E.2    Tanner, J.R.3    Tawaha, K.4    Alali, F.Q.5    Li, C.6    Oberlies, N.H.7
  • 28
  • 29
    • 0000378637 scopus 로고
    • On antibacterial action of culture of Penicillium, with special reference to their use in isolation of B. influenzae
    • Fleming, A. (1929). On antibacterial action of culture of Penicillium, with special reference to their use in isolation of B. influenzae. Br. J. Exp. Pathol. 10, 226-236.
    • (1929) Br. J. Exp. Pathol. , vol.10 , pp. 226-236
    • Fleming, A.1
  • 30
    • 21444447773 scopus 로고    scopus 로고
    • Structure-based phylogeny of the metallo-beta-lactamases
    • Garau, G., Di Guilmi, A. M., and Hall, B. G. (2005). Structure-based phylogeny of the metallo-beta-lactamases. Antimicrob. Agents Chemother. 49, 2778-2784.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 2778-2784
    • Garau, G.1    Di Guilmi, A.M.2    Hall, B.G.3
  • 31
    • 74249119814 scopus 로고    scopus 로고
    • Mobile antibiotic resistance encoding elements promote their own diversity
    • doi: 10.1371/journal.pgen.1000775
    • Garriss, G., Waldor, M. K., and Burrus, V. (2009). Mobile antibiotic resistance encoding elements promote their own diversity. PLoS Genet. 5, e1000775. doi: 10.1371/journal.pgen.1000775.
    • (2009) PLoS Genet , vol.5
    • Garriss, G.1    Waldor, M.K.2    Burrus, V.3
  • 32
    • 77952308483 scopus 로고    scopus 로고
    • Nonprescription antibiotic therapy: cultural models on both sides of the counter and both sides of the border
    • Gartin, M., Brewis, A. A., and Schwartz, N. A. (2010). Nonprescription antibiotic therapy: cultural models on both sides of the counter and both sides of the border. Med. Anthropol. Q. 24, 85-107.
    • (2010) Med. Anthropol. Q. , vol.24 , pp. 85-107
    • Gartin, M.1    Brewis, A.A.2    Schwartz, N.A.3
  • 33
    • 13844254907 scopus 로고    scopus 로고
    • Outpatient antibiotic use in Europe and association with resistance: a cross-national database study
    • ESAC Project Group
    • Goossens, H., Ferech, M., Vander Stichele, R., Elseviers, M., and ESAC Project Group. (2005). Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 365, 579-587.
    • (2005) Lancet , vol.365 , pp. 579-587
    • Goossens, H.1    Ferech, M.2    Vander Stichele, R.3    Elseviers, M.4
  • 34
    • 77949916499 scopus 로고    scopus 로고
    • Two-component signal transduction as potential drug targets in pathogenic bacteria
    • Gotoh, Y., Eguchi, Y., Watanabe, T., Okamoto, S., Doi, A., and Utsumi, R. (2010). Two-component signal transduction as potential drug targets in pathogenic bacteria. Curr. Opin. Microbiol. 13, 232-239.
    • (2010) Curr. Opin. Microbiol. , vol.13 , pp. 232-239
    • Gotoh, Y.1    Eguchi, Y.2    Watanabe, T.3    Okamoto, S.4    Doi, A.5    Utsumi, R.6
  • 35
    • 77956562826 scopus 로고    scopus 로고
    • Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature
    • Griffin, M. O., Fricovsky, E., Ceballos, G., and Villarreal, F. (2010). Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am. J. Physiol. Cell Physiol. 299, C539-C548.
    • (2010) Am. J. Physiol. Cell Physiol. , vol.299
    • Griffin, M.O.1    Fricovsky, E.2    Ceballos, G.3    Villarreal, F.4
  • 37
    • 2942562249 scopus 로고    scopus 로고
    • Evolution of the serine beta-lactamases: past, present and future
    • Hall, B. G., and Barlow, M. (2004). Evolution of the serine beta-lactamases: past, present and future. Drug Resist. Updat. 7, 111-123.
    • (2004) Drug Resist. Updat. , vol.7 , pp. 111-123
    • Hall, B.G.1    Barlow, M.2
  • 38
    • 33845699790 scopus 로고    scopus 로고
    • Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
    • Hancock, R. E., and Sahl, H. G. (2006). Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat. Biotechnol. 24, 1551-1557.
    • (2006) Nat. Biotechnol. , vol.24 , pp. 1551-1557
    • Hancock, R.E.1    Sahl, H.G.2
  • 42
    • 78249286198 scopus 로고    scopus 로고
    • Antibacterials from the sea
    • Hughes, C. C., and Fenical, W. (2010). Antibacterials from the sea. Chemistry 16, 12512-12525.
    • (2010) Chemistry , vol.16 , pp. 12512-12525
    • Hughes, C.C.1    Fenical, W.2
  • 44
    • 0033793926 scopus 로고    scopus 로고
    • Passive immunity in prevention and treatment of infectious diseases
    • Keller, M. A., and Stiehm, E. R. (2000). Passive immunity in prevention and treatment of infectious diseases. Clin. Microbiol. Rev. 13, 602-614.
    • (2000) Clin. Microbiol. Rev. , vol.13 , pp. 602-614
    • Keller, M.A.1    Stiehm, E.R.2
  • 45
    • 35248834509 scopus 로고    scopus 로고
    • Molecular evidence for the ancient origin of the ribosomal protection protein that mediates tetracycline resistance in bacteria
    • Kobayashi, T., Nonaka, L., Maruyama, F., and Suzuki, S. (2007). Molecular evidence for the ancient origin of the ribosomal protection protein that mediates tetracycline resistance in bacteria. J. Mol. Evol. 65, 228-235.
    • (2007) J. Mol. Evol. , vol.65 , pp. 228-235
    • Kobayashi, T.1    Nonaka, L.2    Maruyama, F.3    Suzuki, S.4
  • 46
    • 77952884274 scopus 로고    scopus 로고
    • How antibiotics kill bacteria: from targets to networks
    • Kohanski, M. A., Dwyer, D. J., and Collins, J. J. (2010a). How antibiotics kill bacteria: from targets to networks. Nat. Rev. Microbiol. 8, 423-435.
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 423-435
    • Kohanski, M.A.1    Dwyer, D.J.2    Collins, J.J.3
  • 47
    • 75949092532 scopus 로고    scopus 로고
    • Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis
    • Kohanski, M. A., DePristo, M. A., and Collins, J. J. (2010b). Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. Mol. Cell 37, 311-320.
    • (2010) Mol. Cell , vol.37 , pp. 311-320
    • Kohanski, M.A.1    DePristo, M.A.2    Collins, J.J.3
  • 49
    • 77956328000 scopus 로고    scopus 로고
    • Bacterial charity work leads to population-wide resistance
    • Lee, H. H., Molla, M. N., Cantor, C. R., and Collins, J. J. (2010). Bacterial charity work leads to population-wide resistance. Nature 467, 82-85.
    • (2010) Nature , vol.467 , pp. 82-85
    • Lee, H.H.1    Molla, M.N.2    Cantor, C.R.3    Collins, J.J.4
  • 50
    • 1842455969 scopus 로고    scopus 로고
    • Population and evolutionary dynamics of phage therapy
    • Levin, B. R., and Bull, J. J. (2004). Population and evolutionary dynamics of phage therapy. Nat. Rev. Microbiol. 2, 166-173.
    • (2004) Nat. Rev. Microbiol. , vol.2 , pp. 166-173
    • Levin, B.R.1    Bull, J.J.2
  • 52
    • 13744254730 scopus 로고    scopus 로고
    • The Composition of Ehrlich's Salvarsan: resolution of a century-old debate
    • Lloyd, N. C., Morgan, H. W., Nicholson, B. K., and Ronimus, R. S. (2005). The Composition of Ehrlich's Salvarsan: resolution of a century-old debate. Angew. Chem. Int. Ed. 44, 941-944.
    • (2005) Angew. Chem. Int. Ed. , vol.44 , pp. 941-944
    • Lloyd, N.C.1    Morgan, H.W.2    Nicholson, B.K.3    Ronimus, R.S.4
  • 53
    • 42149131579 scopus 로고    scopus 로고
    • Celldivision inhibitors: new insights for future antibiotics
    • Lock, R. L., and Harry, E. J. (2008). Celldivision inhibitors: new insights for future antibiotics. Nat. Rev. Drug Discov. 7, 324-338.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 324-338
    • Lock, R.L.1    Harry, E.J.2
  • 54
    • 33644499476 scopus 로고    scopus 로고
    • Practical applications and feasibility of efflux pump inhibitors in the clinic--a vision for applied use
    • Lomovskaya, O., and Bostian, K. A. (2006). Practical applications and feasibility of efflux pump inhibitors in the clinic--a vision for applied use. Biochem. Pharmacol. 71, 910-908.
    • (2006) Biochem. Pharmacol. , vol.71 , pp. 910-908
    • Lomovskaya, O.1    Bostian, K.A.2
  • 55
    • 63849290890 scopus 로고    scopus 로고
    • Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy
    • Lu, T. K., and Collins, J. J. (2009). Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc. Natl. Acad. Sci. U.S.A. 106, 4629-4633.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 4629-4633
    • Lu, T.K.1    Collins, J.J.2
  • 57
    • 0000446261 scopus 로고
    • Penicillin treatment of early syphilis. A preliminary report
    • Mahoney, J., Arnold, R., and Harris, A. (1943). Penicillin treatment of early syphilis. A preliminary report. Verer. Dis. Inform. 24, 355-357.
    • (1943) Verer. Dis. Inform. , vol.24 , pp. 355-357
    • Mahoney, J.1    Arnold, R.2    Harris, A.3
  • 59
    • 47749155981 scopus 로고    scopus 로고
    • Antibiotics and antibiotic resistance genes in natural environments
    • Martínez, J. L. (2008). Antibiotics and antibiotic resistance genes in natural environments. Science 321, 365-367.
    • (2008) Science , vol.321 , pp. 365-367
    • Martínez, J.L.1
  • 61
    • 34547629449 scopus 로고    scopus 로고
    • Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium
    • Negrea, A., Bjur, E., and Ygberg, S. E. (2007). Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium. Antimicrob. Agents Chemother. 51, 2867-2876.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 2867-2876
    • Negrea, A.1    Bjur, E.2    Ygberg, S.E.3
  • 62
    • 77956130256 scopus 로고    scopus 로고
    • Brief communication: mass spectroscopic characterization of tetracycline in the skeletal remains of an ancient population from Sudanese Nubia 350-550 CE
    • Nelson, M. L., Dinardo, A., Hochberg, J., and Armelagos, G. J. (2010). Brief communication: mass spectroscopic characterization of tetracycline in the skeletal remains of an ancient population from Sudanese Nubia 350-550 CE. Am. J. Phys. Anthropol. 143, 151-154.
    • (2010) Am. J. Phys. Anthropol. , vol.143 , pp. 151-154
    • Nelson, M.L.1    Dinardo, A.2    Hochberg, J.3    Armelagos, G.J.4
  • 63
    • 77949918387 scopus 로고    scopus 로고
    • Jamming bacterial communication: new approaches for the treatment of infectious diseases
    • Njoroge, J., and Sperandio, V. (2009). Jamming bacterial communication: new approaches for the treatment of infectious diseases. EMBO Mol. Med. 1, 201-210.
    • (2009) EMBO Mol. Med. , vol.1 , pp. 201-210
    • Njoroge, J.1    Sperandio, V.2
  • 64
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: confronting the challenges of antibacterial discovery
    • Payne, D. J., Gwynn, M. N., Holmes, D. J., and Pompliano, D. L. (2007). Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat. Rev. Drug Discov. 6, 29-40.
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3    Pompliano, D.L.4
  • 68
    • 46249084681 scopus 로고    scopus 로고
    • In vitro evaluation of CBR-2092, a novel rifamycinquinolone hybrid antibiotic: studies of the mode of action in Staphylococcus aureus
    • Robertson, G. T., Bonventre, E. J., and Doyle, T. B. (2008). In vitro evaluation of CBR-2092, a novel rifamycinquinolone hybrid antibiotic: studies of the mode of action in Staphylococcus aureus. Antimicrob. Agents Chemother. 52, 2313-2323.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 2313-2323
    • Robertson, G.T.1    Bonventre, E.J.2    Doyle, T.B.3
  • 69
    • 84944441820 scopus 로고
    • Acquired resistance to penicillin and to neoarsphenamine in Spirochaeta recurrentis
    • Rollo, I. M., Williamson, J., and Plackett, R. L. (1952). Acquired resistance to penicillin and to neoarsphenamine in Spirochaeta recurrentis. Br. J. Pharmacol. Chemother. 7, 33-41.
    • (1952) Br. J. Pharmacol. Chemother. , vol.7 , pp. 33-41
    • Rollo, I.M.1    Williamson, J.2    Plackett, R.L.3
  • 70
    • 0031787909 scopus 로고    scopus 로고
    • Aminoacyl tRNA synthetases as targets for new anti-infectives
    • Schimmel, P., Tao, J., and Hill, J. (1998). Aminoacyl tRNA synthetases as targets for new anti-infectives. FASEB J. 12, 1599-1609.
    • (1998) FASEB J , vol.12 , pp. 1599-1609
    • Schimmel, P.1    Tao, J.2    Hill, J.3
  • 71
    • 0004820949 scopus 로고
    • Actinomycin and DNA transcription
    • Sobell, H. M. (1985). Actinomycin and DNA transcription. Proc. Natl. Acad. Sci. U.S.A. 82, 5328-5331.
    • (1985) Proc. Natl. Acad. Sci. U. S. A. , vol.82 , pp. 5328-5331
    • Sobell, H.M.1
  • 72
    • 19344370271 scopus 로고    scopus 로고
    • Molecular characterization of TEM-type betalactamases identified in cold-seep sediments of Edison Seamount (south of Lihir Island, Papua New Guinea)
    • Song, J. S., Jeon, J. H., Lee, J. H., Jeong, S. H., Jeong, B. C., Kim, S. J., Lee, J. H., and Lee, S. H. (2005). Molecular characterization of TEM-type betalactamases identified in cold-seep sediments of Edison Seamount (south of Lihir Island, Papua New Guinea). J. Microbiol. 43, 172-178.
    • (2005) J. Microbiol. , vol.43 , pp. 172-178
    • Song, J.S.1    Jeon, J.H.2    Lee, J.H.3    Jeong, S.H.4    Jeong, B.C.5    Kim, S.J.6    Lee, J.H.7    Lee, S.H.8
  • 73
    • 33947309695 scopus 로고    scopus 로고
    • Emerging bacterial enzyme targets
    • Su, Z., and Honek, J. F. (2007). Emerging bacterial enzyme targets. Curr. Opin. Investig. Drugs 8, 140-149.
    • (2007) Curr. Opin. Investig. Drugs , vol.8 , pp. 140-149
    • Su, Z.1    Honek, J.F.2
  • 74
    • 67049107861 scopus 로고    scopus 로고
    • P1A recombinant β-lactamase prevents emergence of antimicrobial resistance in gut microflora of healthy subjects during intravenous administration of ampicillin
    • Tarkkanen, A. M., Heinonen, T., and Jogi, R. (2009). P1A recombinant β-lactamase prevents emergence of antimicrobial resistance in gut microflora of healthy subjects during intravenous administration of ampicillin.Antimicrob. Agents Chemother. 53, 2455-2462.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 2455-2462
    • Tarkkanen, A.M.1    Heinonen, T.2    Jogi, R.3
  • 76
  • 77
    • 77957820588 scopus 로고    scopus 로고
    • Antibiotic resistance in the environment: a link to the clinic? Curr
    • Wright, G. D. (2010). Antibiotic resistance in the environment: a link to the clinic? Curr. Opin. Microbiol.13, 589-594.
    • (2010) Opin. Microbiol. , vol.13 , pp. 589-594
    • Wright, G.D.1


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