Occurrence and distribution of pharmaceuticals in surface water, suspended solids and sediments of the Ebro river basin, Spain

Chemosphere

Volumn 85, Issue 8, 2011, Pages 1331-1339

  Silva, Bianca Ferreira da ^a,b   Jelic, Aleksandra ^a   López Serna, Rebeca ^a   Mozeto, Antonio A ^b   Petrovic, Mira ^c,d   Barceló, Damià ^a,c,e  

^a INSTITUTE OF ENVIRONMENTAL ASSESSMENT AND WATER RESEARCH   (Spain)

^b FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^c UNIVERSITY OF GIRONA   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^e KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Distribution; Ebro river; Pharmaceuticals; River water; Sediments; Suspended solids; Wastewater

Indexed keywords

DRUG PRODUCTS; EFFLUENTS; RIVERS; SEDIMENTS; SUSPENDED SEDIMENTS; WASTEWATER; WATERSHEDS;

BASIC CHARACTERISTICS; DISTRIBUTION; EBRO RIVER; OCCURRENCE AND DISTRIBUTION; RIVER WATER; SMALL TRIBUTARIES; SUSPENDED SOLIDS; THERAPEUTIC CLASS;

RIVER POLLUTION;

ATENOLOL; ATORVASTATIN; BEZAFIBRATE; CARBAMAZEPINE; CHLORAMPHENICOL; CIMETIDINE; CLARITHROMYCIN; CLENBUTEROL; CLOFIBRIC ACID; DIAZEPAM; DICLOFENAC; ENALAPRIL; ERYTHROMYCIN; FAMOTIDINE; FENOFIBRATE; FUROSEMIDE; GEMFIBROZIL; GLIBENCLAMIDE; HYDROCHLOROTHIAZIDE; IBUPROFEN; INDUSTRIAL EFFLUENT; JOSAMYCIN; KETOPROFEN; LORAZEPAM; MEFENAMIC ACID; METOPROLOL; METRONIDAZOLE; PARACETAMOL; RIVER WATER; UNINDEXED DRUG;

DILUTION; DRUG; POLLUTANT TRANSPORT; RIVER BASIN; RIVER FLOW; RIVER POLLUTION; RIVER WATER; SAMPLING; SPATIAL DISTRIBUTION; SURFACE WATER; SUSPENDED LOAD; WASTEWATER;

ARTICLE; CONCENTRATION (PARAMETERS); RIVER BASIN; SEDIMENT; SPAIN; SUSPENDED PARTICULATE MATTER; WASTE WATER MANAGEMENT; WATER CONTAMINATION;

EBRO BASIN; SPAIN;

EID: 82455199111     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2011.07.051     Document Type: Article

References (25)

1. Bartelt-Hunt S.L., Snow D.D., Damon T., Shockley J., Hoagland K. The occurrence of illicit and therapeutic pharmaceuticals in wastewater effluent and surface waters in Nebraska. Environ. Pollut. 2009, 157(3):786-791.
2. Boxall A.B.A. The environmental side effects of medication. EMBO Reports 2004, 5(12):1110-1116.
3. Ellis J.B. Pharmaceutical and personal care products (PPCPs) in urban receiving waters. Environ. Pollut. 2006, 144(1):184-189.
4. Gago-Ferrero P., Diaz-Cruz S.M., Barcelo D. Fast pressurized liquid extraction with in-cell purification and analysis by LC-tandem MS for the determination of UV filters and their degradation products in sediments. Anal. Bioanal. Chem. 2011, 400(7):2195-2204.
5. Gros M., Petrovic M., Barceló D. Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and wastewaters. Talanta 2006, 70(4):678-690.
6. Gros M., Petrović M., Barceló D. Wastewater treatment plants as a pathway for aquatic contamination by pharmaceuticals in the Ebro river basin (NE Spain). Environ. Toxicol. Chem. 2007, 26(8):1553-1562.
7. Gros M., Petrović M., Barceló D. Tracing pharmaceutical residues of different therapeutic classes in environmental waters by using liquid chromatography/quadrupole-linear ion trap mass spectrometry and automated library searching. Anal. Chem. 2009, 81(3):898-912.
8. Gros M., Petrović M., Ginebreda A., Barceló D. Removal of pharmaceuticals during wastewater treatment and environmental risk assessment using hazard indexes. Environ. Int. 2010, 36:15-26.
9. Grujic S., Vasiljevic T., Lausevic M. Determination of multiple pharmaceutical classes in surface and ground waters by liquid chromatography-ion trap-tandem mass spectrometry. J. Chromatogr. A 2009, 1216(25):4989-5000.
10. Hernando M.D., Heath E., Petrovic M., Barceló D. Trace-level determination of pharmaceutical residues by LC-MS/MS in natural and treated waters: a pilot-survey study. Anal. Bioanal. Chem. 2006, 385:985-991.
11. Jelic A., Petrovic M., Barceló D. Multi-residue method for trace level determination of pharmaceuticals in solid samples using pressurized liquid extraction followed by liquid chromatography/quadrupole-linear ion trap mass spectrometry. Talanta 2009, 80(1):363-371.
12. Khetan S.K., Collins T.J. Human pharmaceuticals in the aquatic environment: a challenge to green chemistry. Chem. Rev. 2007, 107(6):2319-2364.
13. Kwon J.-W., Armbrust K.L. Aqueous solubility, n-octanol-water partition coefficient, and sorption of five selective serotonin reuptake inhibitors to sediments and soils. B. Environ. Contam. Toxicol. 2008, 81:128-135.
14. Lillenberg M., Yurchenko S., Kipper K., Herodes K., Pihl V., Sepp K., Lõhmus R., Nei L. Simultaneous determination of fluoroquinolones, sulfonamides and tetracyclines in sewage sludge by pressurized liquid extraction and liquid chromatography electrospray ionization-mass spectrometry. J. Chromatogr. A 2009, 1216(32):5949-5954.
15. McClellan, K., Halden, R.U., in press. Pharmaceuticals and personal care products in archived US biosolids from the 2001 EPA national sewage sludge survey. Water Res. Corrected Proof.
16. Miège C., Choubert J.M., Ribeiro L., Eusèbe M., Coquery M. Fate of pharmaceuticals and personal care products in wastewater treatment plants - Conception of a database and first results. Environ. Pollut. 2009, 157(5):1721-1726.
17. Miller T.R., Heidler J., Chillrud S.N., DeLaquil A., Ritchie J.C., Mihalic J.N., Bopp R., Halden R.U. Fate of triclosan and evidence for reductive dechlorination of triclocarban in estuarine sediments. Environ. Sci. Technol. 2008, 42(12):4570-4576.
18. Navarro-Ortega A., Tauler R., Lacorte S., Barceló D. Occurrence and transport of PAHs, pesticides and alkylphenols in sediment samples along the Ebro River Basin. J. Hydrol. 2010, 383:5-17.
19. Nieto A., Borrull F., Marcé R.M., Pocurull E. Determination of personal care products in sewage sludge by pressurized liquid extraction and ultra high performance liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 2009, 1216(30):5619-5625.
20. Nilsen, E.B., Rosenbauer, R.R., Furlong, E.T., Burkhardt, M.R., Werner, S.L., Greaser, L., Noriega, M. (2007) Pharmaceuticals, personal care products and anthropogenic waste indicators detected in streambed sediments of the lower Columbia River and selected tributaries National Ground Water Association, Paper 4483, p. 15.
21. Okuda T., Yamashita N., Tanaka H., Matsukawa H., Tanabe K. Development of extraction method of pharmaceuticals and their occurrences found in Japanese wastewater treatment plants. Environ. Int. 2009, 35(5):815-820.
22. Pérez S., Barceló D. Application of advanced MS techniques to analysis and identification of human and microbial metabolites of pharmaceuticals in the aquatic environment. TrAC - Trend Anal. Chem. 2007, 26(6):494-514.
23. Petrovic M., Hernando M.D., Díaz-Cruz S., Barceló D. Liquid chromatography-tandem mass spectrometry for the analysis of pharmaceutical residues in environmental samples: a review. J. Chromatogr. A 2005, 1067:1-14.
24. Radjenovic J., Jelic A., Petrovic M., Barceló D. Determination of pharmaceuticals in sewage sludge by pressurized liquid extraction (PLE) coupled to liquid chromatography-tandem mass spectrometry (LC-MS/MS). Anal. Bioanal. Chem. 2009, 393:1685-1695.
25. Vazquez-Roig P., Segarra R., Blasco C., Andreu V., Picó Y. Determination of pharmaceuticals in soils and sediments by pressurized liquid extraction and liquid chromatography tandem mass spectrometry. J. Chromatogr. A 2010, 1217(16):2471-2483.