Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: A review of recent research data

Toxicology Letters

Volumn 131, Issue 1-2, 2002, Pages 5-17

  Heberer, Thomas ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Bank filtration; PhACs; Sewage contaminants; Surface, ground and drinking water

Indexed keywords

4 AMINOPHENAZONE; ACETYLSALICYLIC ACID; AMINOPHENAZONE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; ANTIPYRETIC AGENT; CARBAMAZEPINE; CLOFIBRIC ACID; CODEINE; DICLOFENAC; DRINKING WATER; DRUG; DRUG METABOLITE; FENOPROFEN; GENTISIC ACID; GROUND WATER; HYDRATROPIC ACID DERIVATIVE; HYDROCODONE; IBUPROFEN; INDOMETACIN; IODINATED CONTRAST MEDIUM; KERATOLYTIC AGENT; KETOPROFEN; PARACETAMOL; PRESERVATIVE; PRIMIDONE; PRODRUG; SALICYLURIC ACID; SURFACE WATER; UNINDEXED DRUG;

DRUG DETERMINATION; DRUG ELIMINATION; DRUG METABOLISM; EFFLUENT; EUROPE; HUMAN; LANDFILL; LEACHING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVIEW; SEWAGE EFFLUENT; SEWAGE TREATMENT; SOIL ANALYSIS; UNITED STATES; WATER ANALYSIS; WATER CONTAMINATION; WATER POLLUTION;

EID: 0037052865     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(02)00041-3     Document Type: Article

References (78)

1. Vorkommen natürlicher und synthetischer östrogener Steroide in Wässern des süd- und mitteldeutschen Raumes
2. Phenazone analgesics in soil and groundwater below a municipal solid waste landfill
3. Determiation of drug residues in water by the combination of liquid chromatography or capillary electrophoresis with electrospray mass spectrometry
4. Occurrence and fate of fluoroquinolone, macrolide, and sulfonamide antibiotics during wastewater treatment and in ambient waters in Switzerland
5. Monitoring natural and synthetic estrogens at activated sludge sewage treatment plants and in a receiving river water
6. Anthropogenic origin of positive gadolinium anomalies in river waters
7. Analysis and occurrence of estrogenic hormones and their glucuronides in surface water and waste water in The Netherlands
8. Wirksamkeit der uferfiltration für die entfernung von polaren organischen spurenstoffen
9. Occurrence of the pharmaceutical drug clofibric acid and the herbicide mecoprop in various Swiss lakes and in the North Sea
10. Occurrence and fate of the pharmaceutical drug diclofenac in surface waters: Rapid photodegradation in a lake
11. Occurrence and environmental behavior of the pharmaceutical drug ibuprofen in surface waters and in wastewater
12. Pharmaceuticals and personal care products in the environment: Agents of subtle change?
13. Identification of estrogenic chemicals in STP effluent. 1. Chemical fractionation and in vitro biological screening
14. Pentobarbital found in ground water
15. Determination of drugs in surface water and wastewater samples by liquid chromatography-mass spectrometry: Methods and preliminary results including toxicity studies with Vibrio fischeri
16. GC/MS analysis of organic compounds in domestic wastewaters
17. Contamination of hospital wastewater with hazardous compounds as defined by §7a WHG
18. Trace determination of fluoroquinolone antibacterial agents in urban wastewater by solid-phase extraction and liquid chromatography with fluorescence detection
19. Occurrence, fate and effects of pharmaceutical substances in the environment - A review
20. Detection and identification of sulphonamide drugs in municipal waste water by liquid chromatography coupled with electrospray ionisation tandem mass spectrometry
21. Identification of fluoroquinolone antibiotics as the main source of umuC genotoxicity in native hospital wastewater
22. Tracking down persistent pharmaceutical residues from municipal sewage to drinking water
23. Detection of drugs and drug metabolites in groundwater samples of a drinking water treatment plant
24. Production of drinking water from highly contaminated surface waters: Removal of organic, inorganic, and microbial contaminants applying mobile membrane filtration units
25. Occurrence of pharmaceutical residues in sewage, river, ground and drinking water in Greece and Germany
26. Natural attenuation of antibiotic and bacteriostatic drug residues during bank filtration
27. From municipal sewage to drinking water: Fate and removal of pharmaceutical residues in the aquatic environment in urban areas
28. Vorkommen von polaren organischen kontaminanten im Berliner Trinkwasser
29. Determination of clofibric acid and N-(phenylsulfonyl)-sarcosine in sewage, river and drinking water
30. Occurrence and fate of pharmaceuticals during bank filtration-preliminary results from investigations in Germany and the United States
31. Drugs and drug metabolites as environmental contaminants: Chlorophenxoyisobutyrate and salicylic acid in sewage water effluent
32. Determination of antibiotics in different water compartments via liquid chromatography-electrospray tandem mass spectrometry
33. Occurrence of antibiotics in the aquatic environment
34. Occurrence and distribution of pharmaceutical organic compounds in the groundwater downgradient of a landfill (Grindsted, Denmark)
35. Analysis of estrogenic hormones in municipal wastewater effluent and surface water using enzyme-linked immunoadsorbent assay and gas chromatography/tandem mass spectrometry
36. Estimating steroid oestrogen inputs into activated sludge treatment works and observations on their removal from the effluent
37. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: Methods, Development and National Reconnaissance
38. Determination of endogenous and exogenous estrogens in effluents from sewage treatment plants at the ng/l-level
39. Riverbank filtration - An overview
40. Drugs in the environment: Emission of drugs, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources - A review
41. Biodegradability of the anti-tumor agent ifosfamide and its occurrence in hospital effluents and communal sewage
42. Hospitals as a source of gadolinium in the aquatic environment
43. Analysis of trace levels of sulfonamide and tetracycline antimicrobials in groundwater and surface water using solid-phase extraction and liquid chromatography/mass spectrometry
44. Bestimmung von schwer abbaubaren organischen verbindungen im abwasser - Identifizierung von arzneimittelrückständen
45. Application of ion-chromatography for the determination of the organic-group parameters AOCl, AOBr and AOI in water
46. Simultaneous quantification of neutral and acidic pharmaceuticals and pesticides at the low-ng/l level in surface and waste water
47. Estrogenic effects of effluents from sewage treatment works
48. Iodierte röntgenkontrastmittel im anthropogen beeinflussten wasserkreislauf
49. Quantification of triiodinated benzene derivatives and X-ray contrast media in water samples by liquid chromatography-electrospray tandem mass spectrometry
50. Occurrence of triiodinated X-ray contrast agents in the aquatic environment
51. Occurrence and identification of phenazone drugs and their metabolites in ground- and drinking water
52. Pharmaceuticals in groundwaters. Analytical methods and results of a monitoring program in Baden-Württemberg, Germany
53. Natural attenuation of pharmaceuticals
54. Factors affecting the concentrations of pharmaceuticals released to the aquatic environment
55. Caffeine and pharmaceuticals as indicators of waste water contamination in wells
56. Schwer abbaubare substanzen mit östrogenartiger wirkung im abwasser von kommunalen und industriellen kläranlagenabläufen
57. Pharmaceuticals in the aquatic environment
58. Vorkommen von clofibrinsäure im aquatischen system-führt die therapeutische anwendung zu einer belastung von oberflächen-, grund- und trinkwasser
59. Identifizierung von 2-(4-Chlorphenoxy)-2-methyl-propionsäure im grundwasser mittels kapillar-gaschromatographie mit atomemissionsdetektion und massenspektrometrie
60. Trace analysis of the antineoplastics ifosfamide and cyclophosphamide in sewage water by two-step solid-phase extraction and gas chromatography-mass spectrometry
61. Biological degradation of cyclophosphamide and its occurrence in sewage water
62. Environmental risk assessment of human pharmaceuticals in Denmark after normal therapeutic use
63. Nachweis von natürlichen und synthetischen östrogenen in kläranlagen und flieβgewässern
64. Isolierung von ibuprofen-metaboliten und deren bedeutung als kontaminanten in der aquatischen umwelt
65. Polar drug residues in sewage and natural waters in the state of Rio de Janeiro, Brazil
66. Occurrence of drugs in German sewage treatment plants and rivers
67. Behavior and occurrence of estrogens in municipal sewage treatment plants - I. Investigations in Germany, Canada and Brazil
68. Behavior and occurrence of estrogens in municipal sewage treatment plants - II. Aerobic batch experiments with activated sludge
69. Pharmaceuticals and metabolites as contaminants of the aquatic environment
70. Determination of neutral pharmaceuticals in wastewater and rivers by liquid chromatography-electrospray tandem mass spectrometry
71. Occurrence and behavior of X-ray contrast media in sewage facilities and the aquatic environment
72. Simultaneous determination of antiseptics and acidic drugs in sewage and river water
73. Occurrence, characteristics, and transport and fate of pesticides, pharmaceutical active compounds, and industrial and personal care products at bank-filtration sites
74. Automatisierte bestimmung polarer arzneimittelrückstände in wässern mittels festphasenmikroextraktion (SPME) und derivatisierung
75. Analysis of estrogens in river water and effluents using solid-phase extraction and gas chromatography-negative chemical ionisation mass spectrometry of the pentafluorobenzoyl derivatives
76. Oxidative treatment of pharmaceuticals in water
77. Biodegradation of pharmaceutical residues investigated by SPE-GC/ITD-MS and on-line derivatization