-
1
-
-
13444282230
-
Protein S-nitrosylation: Purview and parameters
-
Hess DT, Matsumoto A, Kim SO, Marshall HE, Stamler JS. Protein S-nitrosylation: purview and parameters. Nat Rev Mol Cell Biol. 2005;6(2):150-166.
-
(2005)
Nat Rev Mol Cell Biol.
, vol.6
, Issue.2
, pp. 150-166
-
-
Hess, D.T.1
Matsumoto, A.2
Kim, S.O.3
Marshall, H.E.4
Stamler, J.S.5
-
2
-
-
45049085873
-
Redox-based regulation of signal transduction: Principles, pitfalls, and promises
-
Janssen-Heininger YM, et al. Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic Biol Med. 2008;45(1):1-17.
-
(2008)
Free Radic Biol Med.
, vol.45
, Issue.1
, pp. 1-17
-
-
Janssen-Heininger, Y.M.1
-
3
-
-
84884179284
-
The redox proteome
-
Go YM, Jones DP. The redox proteome. J Biol Chem. 2013;288(37):26512-26520.
-
(2013)
J Biol Chem.
, vol.288
, Issue.37
, pp. 26512-26520
-
-
Go, Y.M.1
Jones, D.P.2
-
4
-
-
33845428642
-
Thioredoxin and related molecules - From biology to health and disease
-
Lillig CH, Holmgren A. Thioredoxin and related molecules - from biology to health and disease. Antioxid Redox Signal. 2007;9(1):25-47.
-
(2007)
Antioxid Redox Signal
, vol.9
, Issue.1
, pp. 25-47
-
-
Lillig, C.H.1
Holmgren, A.2
-
5
-
-
84875700217
-
Protein glutathionylation in health and disease
-
Ghezzi P. Protein glutathionylation in health and disease. Biochim Biophys Acta. 2013;1830(5):3165-3172.
-
(2013)
Biochim Biophys Acta
, vol.1830
, Issue.5
, pp. 3165-3172
-
-
Ghezzi, P.1
-
6
-
-
84866601999
-
Glutathione synthesis and its role in redox signaling
-
Zhang H, Forman HJ. Glutathione synthesis and its role in redox signaling. Semin Cell Dev Biol. 2012;23(7):722-728.
-
(2012)
Semin Cell Dev Biol.
, vol.23
, Issue.7
, pp. 722-728
-
-
Zhang, H.1
Forman, H.J.2
-
7
-
-
70349466515
-
Protein denitrosylation: Enzymatic mechanisms and cellular functions
-
Benhar M, Forrester MT, Stamler JS. Protein denitrosylation: enzymatic mechanisms and cellular functions. Nat Rev Mol Cell Biol. 2009;10(10):721-732.
-
(2009)
Nat Rev Mol Cell Biol.
, vol.10
, Issue.10
, pp. 721-732
-
-
Benhar, M.1
Forrester, M.T.2
Stamler, J.S.3
-
8
-
-
78549288556
-
Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation
-
Mandal PK, et al. Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation. Cancer Res. 2010;70(22):9505-9514.
-
(2010)
Cancer Res.
, vol.70
, Issue.22
, pp. 9505-9514
-
-
Mandal, P.K.1
-
9
-
-
84856219754
-
Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1
-
Prigge JR, et al. Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1. Free Radic Biol Med. 2012;52(4):803-810.
-
(2012)
Free Radic Biol Med.
, vol.52
, Issue.4
, pp. 803-810
-
-
Prigge, J.R.1
-
10
-
-
84941247999
-
Human CD4+ T cells require exogenous cystine for glutathione and DNA synthesis
-
Levring TB, et al. Human CD4+ T cells require exogenous cystine for glutathione and DNA synthesis. Oncotarget. 2015;6(26):21853-21864.
-
(2015)
Oncotarget
, vol.6
, Issue.26
, pp. 21853-21864
-
-
Levring, T.B.1
-
11
-
-
84868328588
-
Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose
-
Du Y, Zhang H, Lu J, Holmgren A. Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose. J Biol Chem. 2012;287(45):38210-38219.
-
(2012)
J Biol Chem
, vol.287
, Issue.45
, pp. 38210-38219
-
-
Du, Y.1
Zhang, H.2
Lu, J.3
Holmgren, A.4
-
12
-
-
77957315403
-
Redox compartmentalization and cellular stress
-
Jones DP, Go YM. Redox compartmentalization and cellular stress. Diabetes Obes Metab. 2010;12(suppl 2):116-125.
-
(2010)
Diabetes Obes Metab.
, vol.12
, pp. 116-125
-
-
Jones, D.P.1
Go, Y.M.2
-
13
-
-
84887114785
-
Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems
-
Go YM, et al. Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems. Mol Cell Proteomics. 2013;12(11):3285-3296.
-
(2013)
Mol Cell Proteomics
, vol.12
, Issue.11
, pp. 3285-3296
-
-
Go, Y.M.1
-
14
-
-
84900498924
-
Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase
-
Pader I, et al. Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase. Proc Natl Acad Sci U S A. 2014;111(19):6964-6969.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.19
, pp. 6964-6969
-
-
Pader, I.1
-
15
-
-
84942358036
-
Nitric oxide and the thioredoxin system: A complex interplay in redox regulation
-
Benhar M. Nitric oxide and the thioredoxin system: A complex interplay in redox regulation. Biochim Biophys Acta. 2015;1850(12):2476-2484.
-
(2015)
Biochim Biophys Acta
, vol.1850
, Issue.12
, pp. 2476-2484
-
-
Benhar, M.1
-
16
-
-
84892366219
-
The thioredoxin antioxidant system
-
Lu J, Holmgren A. The thioredoxin antioxidant system. Free Radic Biol Med. 2014;66:75-87.
-
(2014)
Free Radic Biol Med
, vol.66
, pp. 75-87
-
-
Lu, J.1
Holmgren, A.2
-
17
-
-
84886587812
-
Quantitative redox biology: An approach to understand the role of reactive species in defining the cellular redox environment
-
Buettner GR, Wagner BA, Rodgers VG. Quantitative redox biology: an approach to understand the role of reactive species in defining the cellular redox environment. Cell Biochem Biophys. 2013;67(2):477-483.
-
(2013)
Cell Biochem Biophys
, vol.67
, Issue.2
, pp. 477-483
-
-
Buettner, G.R.1
Wagner, B.A.2
Rodgers, V.G.3
-
18
-
-
77954935933
-
A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses
-
Adimora NJ, Jones DP, Kemp ML. A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses. Antioxid Redox Signal. 2010;13(6):731-743.
-
(2010)
Antioxid Redox Signal
, vol.13
, Issue.6
, pp. 731-743
-
-
Adimora, N.J.1
Jones, D.P.2
Kemp, M.L.3
-
19
-
-
84875147636
-
Redox regulation of T-cell function: From molecular mechanisms to significance in human health and disease
-
Kesarwani P, Murali AK, Al-Khami AA, Mehrotra S. Redox regulation of T-cell function: from molecular mechanisms to significance in human health and disease. Antioxid Redox Signal. 2013;18(12):1497-1534.
-
(2013)
Antioxid Redox Signal
, vol.18
, Issue.12
, pp. 1497-1534
-
-
Kesarwani, P.1
Murali, A.K.2
Al-Khami, A.A.3
Mehrotra, S.4
-
20
-
-
84906258572
-
Integrative biology of T cell activation
-
Malissen B, Grégoire C, Malissen M, Roncagalli R. Integrative biology of T cell activation. Nat Immunol. 2014;15(9):790-797.
-
(2014)
Nat Immunol
, vol.15
, Issue.9
, pp. 790-797
-
-
Malissen, B.1
Grégoire, C.2
Malissen, M.3
Roncagalli, R.4
-
21
-
-
84927924524
-
Redox regulation of T-cell receptor signaling
-
Simeoni L, Bogeski I. Redox regulation of T-cell receptor signaling. Biol Chem. 2015;396(5):555-568.
-
(2015)
Biol Chem
, vol.396
, Issue.5
, pp. 555-568
-
-
Simeoni, L.1
Bogeski, I.2
-
22
-
-
38449118436
-
The requirement of reversible cysteine sulfenic acid formation for T cell activation and function
-
Michalek RD, et al. The requirement of reversible cysteine sulfenic acid formation for T cell activation and function. J Immunol. 2007;179(10):6456-6467.
-
(2007)
J Immunol
, vol.179
, Issue.10
, pp. 6456-6467
-
-
Michalek, R.D.1
-
23
-
-
84867871087
-
Redox control of cell proliferation
-
Chiu J, Dawes IW. Redox control of cell proliferation. Trends Cell Biol. 2012;22(11):592-601.
-
(2012)
Trends Cell Biol
, vol.22
, Issue.11
, pp. 592-601
-
-
Chiu, J.1
Dawes, I.W.2
-
24
-
-
77956300467
-
Redox remodeling allows and controls B-cell activation and differentiation
-
Vené R, et al. Redox remodeling allows and controls B-cell activation and differentiation. Antioxid Redox Signal. 2010;13(8):1145-1155.
-
(2010)
Antioxid Redox Signal
, vol.13
, Issue.8
, pp. 1145-1155
-
-
Vené, R.1
-
25
-
-
33845432813
-
Contribution of thioredoxin reductase to T-cell mitogenesis and NF-kappaB DNA-binding promoted by selenite
-
Ueno H, Kajihara H, Nakamura H, Yodoi J, Nakamuro K. Contribution of thioredoxin reductase to T-cell mitogenesis and NF-kappaB DNA-binding promoted by selenite. Antioxid Redox Signal. 2007;9(1):115-121.
-
(2007)
Antioxid Redox Signal
, vol.9
, Issue.1
, pp. 115-121
-
-
Ueno, H.1
Kajihara, H.2
Nakamura, H.3
Yodoi, J.4
Nakamuro, K.5
-
26
-
-
84891751192
-
A candidate anti-HIV reservoir compound, auranofin, exerts a selective anti-memory effect by exploiting the baseline oxidative status of lymphocytes
-
Chirullo B, et al. A candidate anti-HIV reservoir compound, auranofin, exerts a selective 'anti-memory' effect by exploiting the baseline oxidative status of lymphocytes. Cell Death Dis. 2013;4:e944.
-
(2013)
Cell Death Dis.
, vol.4
, pp. e944
-
-
Chirullo, B.1
-
27
-
-
79960014190
-
Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension
-
Lewis MG, et al. Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension. AIDS. 2011;25(11):1347-1356.
-
(2011)
AIDS
, vol.25
, Issue.11
, pp. 1347-1356
-
-
Lewis, M.G.1
-
28
-
-
0037022345
-
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation
-
Angelini G, et al. Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation. Proc Natl Acad Sci U S A. 2002;99(3):1491-1496.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.3
, pp. 1491-1496
-
-
Angelini, G.1
-
29
-
-
70349314830
-
Extracellular redox modulation by regulatory T cells
-
Yan Z, Garg SK, Kipnis J, Banerjee R. Extracellular redox modulation by regulatory T cells. Nat Chem Biol. 2009;5(10):721-723.
-
(2009)
Nat Chem Biol.
, vol.5
, Issue.10
, pp. 721-723
-
-
Yan, Z.1
Garg, S.K.2
Kipnis, J.3
Banerjee, R.4
-
30
-
-
84859739753
-
+ T cells express transporters for both cysteine and cystine
-
Levring TB, et al. Activated human CD4+ T cells express transporters for both cysteine and cystine. Sci Rep. 2012;2:266.
-
(2012)
Sci Rep.
, vol.2
, pp. 266
-
-
Levring, T.B.1
-
31
-
-
0024426194
-
Cell cycle progression of glutathione-depleted human peripheral blood mononuclear cells is inhibited at S phase
-
Messina JP, Lawrence DA. Cell cycle progression of glutathione-depleted human peripheral blood mononuclear cells is inhibited at S phase. J Immunol. 1989;143(6):1974-1981.
-
(1989)
J Immunol.
, vol.143
, Issue.6
, pp. 1974-1981
-
-
Messina, J.P.1
Lawrence, D.A.2
-
32
-
-
84884179149
-
Causes and consequences of cysteine S-glutathionylation
-
Grek CL, Zhang J, Manevich Y, Townsend DM, Tew KD. Causes and consequences of cysteine S-glutathionylation. J Biol Chem. 2013;288(37):26497-26504.
-
(2013)
J Biol Chem.
, vol.288
, Issue.37
, pp. 26497-26504
-
-
Grek, C.L.1
Zhang, J.2
Manevich, Y.3
Townsend, D.M.4
Tew, K.D.5
-
33
-
-
84884194110
-
Regulation of protein function and signaling by reversible cysteine S-nitrosylation
-
Gould N, Doulias PT, Tenopoulou M, Raju K, Ischiropoulos H. Regulation of protein function and signaling by reversible cysteine S-nitrosylation. J Biol Chem. 2013;288(37):26473-26479.
-
(2013)
J Biol Chem.
, vol.288
, Issue.37
, pp. 26473-26479
-
-
Gould, N.1
Doulias, P.T.2
Tenopoulou, M.3
Raju, K.4
Ischiropoulos, H.5
-
34
-
-
0027437490
-
The interaction of auranofin and buthionine sulfoximine blocks activation of human peripheral T lymphocytes
-
Vint IA, Chain BM, Foreman JC. The interaction of auranofin and buthionine sulfoximine blocks activation of human peripheral T lymphocytes. Cell Immunol. 1993;152(1):152-161.
-
(1993)
Cell Immunol
, vol.152
, Issue.1
, pp. 152-161
-
-
Vint, I.A.1
Chain, B.M.2
Foreman, J.C.3
-
35
-
-
84937682389
-
Two-year follow-up of macaques developing intermittent control of the human immunodeficiency virus homolog simian immunodeficiency virus SIVmac251 in the chronic phase of infection
-
Shytaj IL, et al. Two-year follow-up of macaques developing intermittent control of the human immunodeficiency virus homolog simian immunodeficiency virus SIVmac251 in the chronic phase of infection. J Virol. 2015;89(15):7521-7535.
-
(2015)
J Virol
, vol.89
, Issue.15
, pp. 7521-7535
-
-
Shytaj, I.L.1
-
36
-
-
84922056020
-
The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells
-
Lanna A, Henson SM, Escors D, Akbar AN. The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells. Nat Immunol. 2014;15(10):965-972.
-
(2014)
Nat Immunol
, vol.15
, Issue.10
, pp. 965-972
-
-
Lanna, A.1
Henson, S.M.2
Escors, D.3
Akbar, A.N.4
-
37
-
-
84924228289
-
Nitric oxide synthase in innate and adaptive immunity: An update
-
Bogdan C. Nitric oxide synthase in innate and adaptive immunity: an update. Trends Immunol. 2015;36(3):161-178.
-
(2015)
Trends Immunol
, vol.36
, Issue.3
, pp. 161-178
-
-
Bogdan, C.1
-
38
-
-
0028658374
-
Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation
-
Mannick JB, Asano K, Izumi K, Kieff E, Stamler JS. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Cell. 1994;79(7):1137-1146.
-
(1994)
Cell
, vol.79
, Issue.7
, pp. 1137-1146
-
-
Mannick, J.B.1
Asano, K.2
Izumi, K.3
Kieff, E.4
Stamler, J.S.5
-
39
-
-
33744972519
-
Endothelial nitric oxide synthase regulates T cell receptor signaling at the immunological synapse
-
Ibiza S, et al. Endothelial nitric oxide synthase regulates T cell receptor signaling at the immunological synapse. Immunity. 2006;24(6):753-765.
-
(2006)
Immunity
, vol.24
, Issue.6
, pp. 753-765
-
-
Ibiza, S.1
-
40
-
-
48749099188
-
Endothelial nitric oxide synthase regulates N-Ras activation on the Golgi complex of antigen-stimulated T cells
-
Ibiza S, et al. Endothelial nitric oxide synthase regulates N-Ras activation on the Golgi complex of antigen-stimulated T cells. Proc Natl Acad Sci U S A. 2008;105(30):10507-10512.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.30
, pp. 10507-10512
-
-
Ibiza, S.1
-
41
-
-
44449119080
-
Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins
-
Benhar M, Forrester MT, Hess DT, Stamler JS. Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science. 2008;320(5879):1050-1054.
-
(2008)
Science
, vol.320
, Issue.5879
, pp. 1050-1054
-
-
Benhar, M.1
Forrester, M.T.2
Hess, D.T.3
Stamler, J.S.4
-
42
-
-
10744230465
-
Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock
-
Liu L, et al. Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell. 2004;116(4):617-628.
-
(2004)
Cell
, vol.116
, Issue.4
, pp. 617-628
-
-
Liu, L.1
-
43
-
-
0035984912
-
ROS, stress-activated kinases and stress signaling in cancer
-
Benhar M, Engelberg D, Levitzki A. ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep. 2002;3(5):420-425.
-
(2002)
EMBO Rep.
, vol.3
, Issue.5
, pp. 420-425
-
-
Benhar, M.1
Engelberg, D.2
Levitzki, A.3
-
44
-
-
77955274524
-
Redox metabolism and malignancy
-
Grek CL, Tew KD. Redox metabolism and malignancy. Curr Opin Pharmacol. 2010;10(4):362-368.
-
(2010)
Curr Opin Pharmacol
, vol.10
, Issue.4
, pp. 362-368
-
-
Grek, C.L.1
Tew, K.D.2
-
45
-
-
84887621539
-
Redox molecular machines involved in tumor progression
-
Parri M, Chiarugi P. Redox molecular machines involved in tumor progression. Antioxid Redox Signal. 2013;19(15):1828-1845.
-
(2013)
Antioxid Redox Signal
, vol.19
, Issue.15
, pp. 1828-1845
-
-
Parri, M.1
Chiarugi, P.2
-
46
-
-
84886023236
-
Redox imbalance and biochemical changes in cancer
-
Jorgenson TC, Zhong W, Oberley TD. Redox imbalance and biochemical changes in cancer. Cancer Res. 2013;73(20):6118-6123.
-
(2013)
Cancer Res.
, vol.73
, Issue.20
, pp. 6118-6123
-
-
Jorgenson, T.C.1
Zhong, W.2
Oberley, T.D.3
-
47
-
-
84894031033
-
Inflammation, DAMPs, tumor development, and progression: A vicious circle orchestrated by redox signaling
-
Castellani P, Balza E, Rubartelli A. Inflammation, DAMPs, tumor development, and progression: a vicious circle orchestrated by redox signaling. Antioxid Redox Signal. 2014;20(7):1086-1097.
-
(2014)
Antioxid Redox Signal
, vol.20
, Issue.7
, pp. 1086-1097
-
-
Castellani, P.1
Balza, E.2
Rubartelli, A.3
-
48
-
-
84874779118
-
The yin and yang of nitric oxide in cancer progression
-
Burke AJ, Sullivan FJ, Giles FJ, Glynn SA. The yin and yang of nitric oxide in cancer progression. Carcinogenesis. 2013;34(3):503-512.
-
(2013)
Carcinogenesis
, vol.34
, Issue.3
, pp. 503-512
-
-
Burke, A.J.1
Sullivan, F.J.2
Giles, F.J.3
Glynn, S.A.4
-
49
-
-
0034011261
-
Oxyradicals and DNA damage
-
Marnett LJ. Oxyradicals and DNA damage. Carcinogenesis. 2000;21(3):361-370.
-
(2000)
Carcinogenesis
, vol.21
, Issue.3
, pp. 361-370
-
-
Marnett, L.J.1
-
51
-
-
67650071137
-
Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
-
Trachootham D, Alexandre J, Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov. 2009;8(7):579-591.
-
(2009)
Nat Rev Drug Discov.
, vol.8
, Issue.7
, pp. 579-591
-
-
Trachootham, D.1
Alexandre, J.2
Huang, P.3
-
52
-
-
84889575198
-
Modulation of oxidative stress as an anticancer strategy
-
Gorrini C, Harris IS, Mak TW. Modulation of oxidative stress as an anticancer strategy. Nat Rev Drug Discov. 2013;12(12):931-947.
-
(2013)
Nat Rev Drug Discov.
, vol.12
, Issue.12
, pp. 931-947
-
-
Gorrini, C.1
Harris, I.S.2
Mak, T.W.3
-
53
-
-
84908153270
-
Targeting antioxidants for cancer therapy
-
Glasauer A, Chandel NS. Targeting antioxidants for cancer therapy. Biochem Pharmacol. 2014;92(1):90-101.
-
(2014)
Biochem Pharmacol
, vol.92
, Issue.1
, pp. 90-101
-
-
Glasauer, A.1
Chandel, N.S.2
-
54
-
-
10344238570
-
α-Tocopherol and β-carotene supplements and lung cancer incidence in the α-tocopherol, β-carotene cancer prevention study: Effects of base-line characteristics and study compliance
-
Albanes D, et al. α-Tocopherol and β-carotene supplements and lung cancer incidence in the α-tocopherol, β-carotene cancer prevention study: effects of base-line characteristics and study compliance. J Natl Cancer Inst. 1996;88(21):1560-1570.
-
(1996)
J Natl Cancer Inst.
, vol.88
, Issue.21
, pp. 1560-1570
-
-
Albanes, D.1
-
55
-
-
9244262406
-
Effects of a combination of beta carotene and Vitamin A on lung cancer and cardiovascular disease
-
Omenn GS, et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996;334(18):1150-1155.
-
(1996)
N Engl J Med.
, vol.334
, Issue.18
, pp. 1150-1155
-
-
Omenn, G.S.1
-
56
-
-
84890843927
-
Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer: An updated systematic evidence review for the U. S Preventive Services Task Force
-
Fortmann SP, Burda BU, Senger CA, Lin JS, Whitlock EP. Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer: An updated systematic evidence review for the U.S. Preventive Services Task Force. Ann Intern Med. 2013;159(12):824-834.
-
(2013)
Ann Intern Med.
, vol.159
, Issue.12
, pp. 824-834
-
-
Fortmann, S.P.1
Burda, B.U.2
Senger, C.A.3
Lin, J.S.4
Whitlock, E.P.5
-
57
-
-
84946903513
-
Oxidative stress inhibits distant metastasis by human melanoma cells
-
Piskounova E, et al. Oxidative stress inhibits distant metastasis by human melanoma cells. Nature. 2015;5 27(7577):186-191.
-
(2015)
Nature
, vol.527
, Issue.7577
, pp. 186-191
-
-
Piskounova, E.1
-
58
-
-
84946919734
-
Cancer: The enemy of my enemy is my friend
-
Harris IS, Brugge JS. Cancer: The enemy of my enemy is my friend. Nature. 2015;527(7577):170-171.
-
(2015)
Nature
, vol.527
, Issue.7577
, pp. 170-171
-
-
Harris, I.S.1
Brugge, J.S.2
-
59
-
-
84949679802
-
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH
-
Yun J, et al. Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science. 2015;350(6266):1391-1396.
-
(2015)
Science
, vol.350
, Issue.6266
, pp. 1391-1396
-
-
Yun, J.1
-
60
-
-
0042807630
-
The thioredoxin-thioredoxin reductase system: Over-expression in human cancer
-
Lincoln DT, Ali Emadi EM, Tonissen KF, Clarke FM. The thioredoxin-thioredoxin reductase system: over-expression in human cancer. Anticancer Res. 2003;23(3B):2425-2433.
-
(2003)
Anticancer Res
, vol.23
, Issue.3 B
, pp. 2425-2433
-
-
Lincoln, D.T.1
Ali Emadi, E.M.2
Tonissen, K.F.3
Clarke, F.M.4
-
61
-
-
0033796101
-
The role of the redox protein thioredoxin in cell growth and cancer
-
Powis G, Mustacich D, Coon A. The role of the redox protein thioredoxin in cell growth and cancer. Free Radic Biol Med. 2000;29(3-4):312-322.
-
(2000)
Free Radic Biol Med.
, vol.29
, Issue.3-4
, pp. 312-322
-
-
Powis, G.1
Mustacich, D.2
Coon, A.3
-
62
-
-
33751178410
-
The thioredoxin system in cancer
-
Arnér ES, Holmgren A. The thioredoxin system in cancer. Semin Cancer Biol. 2006;16(6):419.
-
(2006)
Semin Cancer Biol.
, vol.16
, Issue.6
, pp. 419
-
-
Arnér, E.S.1
Holmgren, A.2
-
63
-
-
84951572764
-
Thioredoxin 1 in prostate tissue is associated with gleason score, erythrocyte antioxidant enzyme activity, and dietary antioxidants
-
Vance TM, et al. Thioredoxin 1 in prostate tissue is associated with gleason score, erythrocyte antioxidant enzyme activity, and dietary antioxidants. Prostate Cancer. 2015;2015:728046.
-
(2015)
Prostate Cancer
, vol.2015
, pp. 728046
-
-
Vance, T.M.1
-
64
-
-
84926322394
-
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumorderived angiogenesis
-
Hellfritsch J, et al. Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumorderived angiogenesis. Antioxid Redox Signal. 2015;22(11):938-950.
-
(2015)
Antioxid Redox Signal
, vol.22
, Issue.11
, pp. 938-950
-
-
Hellfritsch, J.1
-
65
-
-
84900019686
-
Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia
-
Fiskus W, et al. Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia. Cancer Res. 2014;74(9):2520-2532.
-
(2014)
Cancer Res
, vol.74
, Issue.9
, pp. 2520-2532
-
-
Fiskus, W.1
-
66
-
-
84942509797
-
Preclinical activity of the repurposed drug auranofin in classical Hodgkin lymphoma
-
Celegato M, et al. Preclinical activity of the repurposed drug auranofin in classical Hodgkin lymphoma. Blood. 2015;126(11):1394-1397.
-
(2015)
Blood
, vol.126
, Issue.11
, pp. 1394-1397
-
-
Celegato, M.1
-
67
-
-
3242772761
-
Auranofin induces apoptosis and when combined with retinoic acid enhances differentiation of acute promyelocytic leukaemia cells in vitro
-
Kim IS, Jin JY, Lee IH, Park SJ. Auranofin induces apoptosis and when combined with retinoic acid enhances differentiation of acute promyelocytic leukaemia cells in vitro. Br J Pharmacol. 2004;142(4):749-755.
-
(2004)
Br J Pharmacol
, vol.142
, Issue.4
, pp. 749-755
-
-
Kim, I.S.1
Jin, J.Y.2
Lee, I.H.3
Park, S.J.4
-
68
-
-
79960419089
-
Anticancer activity of metal complexes: Involvement of redox processes
-
Jungwirth U, Kowol CR, Keppler BK, Hartinger CG, Berger W, Heffeter P. Anticancer activity of metal complexes: involvement of redox processes. Antioxid Redox Signal. 2011;15(4):1085-1127.
-
(2011)
Antioxid Redox Signal
, vol.15
, Issue.4
, pp. 1085-1127
-
-
Jungwirth, U.1
Kowol, C.R.2
Keppler, B.K.3
Hartinger, C.G.4
Berger, W.5
Heffeter, P.6
-
69
-
-
84940036765
-
Spatio-temporal changes in glutathione and thioredoxin redox couples during ionizing radiation-induced oxidative stress regulate tumor radio-resistance
-
Patwardhan RS, Sharma D, Checker R, Thoh M, Sandur SK. Spatio-temporal changes in glutathione and thioredoxin redox couples during ionizing radiation-induced oxidative stress regulate tumor radio-resistance. Free Radic Res. 2015;49(10):1218-1232.
-
(2015)
Free Radic Res
, vol.49
, Issue.10
, pp. 1218-1232
-
-
Patwardhan, R.S.1
Sharma, D.2
Checker, R.3
Thoh, M.4
Sandur, S.K.5
-
70
-
-
80053506739
-
Enhancement of carboplatin-mediated lung cancer cell killing by simultaneous disruption of glutathione and thioredoxin metabolism
-
Fath MA, Ahmad IM, Smith CJ, Spence J, Spitz DR. Enhancement of carboplatin-mediated lung cancer cell killing by simultaneous disruption of glutathione and thioredoxin metabolism. Clin Cancer Res. 2011;17(19):6206-6217.
-
(2011)
Clin Cancer Res.
, vol.17
, Issue.19
, pp. 6206-6217
-
-
Fath, M.A.1
Ahmad, I.M.2
Smith, C.J.3
Spence, J.4
Spitz, D.R.5
-
71
-
-
77649290545
-
JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1
-
Edes K, Cassidy P, Shami PJ, Moos PJ. JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1. PLoS One. 2010;5(1):e8786.
-
(2010)
PLoS One
, vol.5
, Issue.1
, pp. e8786
-
-
Edes, K.1
Cassidy, P.2
Shami, P.J.3
Moos, P.J.4
-
72
-
-
84870342895
-
Maintenance of S-nitrosothiol homeostasis plays an important role in growth suppression of estrogen receptor-positive breast tumors
-
Cañas A, et al. Maintenance of S-nitrosothiol homeostasis plays an important role in growth suppression of estrogen receptor-positive breast tumors. Breast Cancer Res. 2012;14(6):R153.
-
(2012)
Breast Cancer Res.
, vol.14
, Issue.6
, pp. R153
-
-
Cañas, A.1
-
73
-
-
84988525471
-
Auranofin induces a reversible in-vivo stress response that correlates with a transient clinical effect in patients with chronic lymphocytic leukemia
-
Saba NS, et al. Auranofin induces a reversible in-vivo stress response that correlates with a transient clinical effect in patients with chronic lymphocytic leukemia. Blood. 2013;122(21):3819.
-
(2013)
Blood
, vol.122
, Issue.21
, pp. 3819
-
-
Saba, N.S.1
-
74
-
-
84907971362
-
CUSP9&z.ast; treatment protocol for recurrent glioblastoma: Aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide
-
Kast RE, Karpel-Massler G, Halatsch ME. CUSP9&z.ast; treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide. Oncotarget. 2014;5(18):8052-8082.
-
(2014)
Oncotarget
, vol.5
, Issue.18
, pp. 8052-8082
-
-
Kast, R.E.1
Karpel-Massler, G.2
Halatsch, M.E.3
-
75
-
-
84878711134
-
Role of glutathione in cancer progression and chemoresistance
-
Traverso N, et al. Role of glutathione in cancer progression and chemoresistance. Oxid Med Cell Longev. 2013;2013:972913.
-
(2013)
Oxid Med Cell Longev
, vol.2013
, pp. 972913
-
-
Traverso, N.1
-
77
-
-
84862777168
-
Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia
-
Zhang W, et al. Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia. Nat Cell Biol. 2012;14(3):276-286.
-
(2012)
Nat Cell Biol.
, vol.14
, Issue.3
, pp. 276-286
-
-
Zhang, W.1
-
79
-
-
79960060305
-
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
-
DeNicola GM, et al. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature. 2011;475(7354):106-109.
-
(2011)
Nature
, vol.475
, Issue.7354
, pp. 106-109
-
-
DeNicola, G.M.1
-
80
-
-
0029052835
-
Evidence for altered regulation of gamma-glutamylcysteine synthetase gene expression among cisplatin-sensitive and cisplatin-resistant human ovarian cancer cell lines
-
Yao KS, Godwin AK, Johnson SW, Ozols RF, O'Dwyer PJ, Hamilton TC. Evidence for altered regulation of gamma-glutamylcysteine synthetase gene expression among cisplatin-sensitive and cisplatin-resistant human ovarian cancer cell lines. Cancer Res. 1995;55(19):4367-4374.
-
(1995)
Cancer Res.
, vol.55
, Issue.19
, pp. 4367-4374
-
-
Yao, K.S.1
Godwin, A.K.2
Johnson, S.W.3
Ozols, R.F.4
O'Dwyer, P.J.5
Hamilton, T.C.6
-
81
-
-
0642374221
-
The role of glutathione-S-transferase in anti-cancer drug resistance
-
Townsend DM, Tew KD. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene. 2003;22(47):7369-7375.
-
(2003)
Oncogene
, vol.22
, Issue.47
, pp. 7369-7375
-
-
Townsend, D.M.1
Tew, K.D.2
-
82
-
-
77955713764
-
Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death
-
Laborde E. Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death. Cell Death Differ. 2010;17(9):1373-1380.
-
(2010)
Cell Death Differ.
, vol.17
, Issue.9
, pp. 1373-1380
-
-
Laborde, E.1
-
83
-
-
84922783167
-
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression
-
Harris IS, et al. Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression. Cancer Cell. 2015;27(2):211-222.
-
(2015)
Cancer Cell
, vol.27
, Issue.2
, pp. 211-222
-
-
Harris, I.S.1
-
84
-
-
84875723942
-
Glutathione and glutathione analogues; therapeutic potentials
-
Wu JH, Batist G. Glutathione and glutathione analogues; therapeutic potentials. Biochim Biophys Acta. 2013;1830(5):3350-3353.
-
(2013)
Biochim Biophys Acta
, vol.1830
, Issue.5
, pp. 3350-3353
-
-
Wu, J.H.1
Batist, G.2
-
85
-
-
9044254931
-
Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer
-
O'Dwyer PJ, et al. Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer. J Clin Oncol. 1996;14(1):249-256.
-
(1996)
J Clin Oncol
, vol.14
, Issue.1
, pp. 249-256
-
-
O'Dwyer, P.J.1
-
86
-
-
0030658870
-
Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan
-
Bailey HH, et al. Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan. J Natl Cancer Inst. 1997;89(23):1789-1796.
-
(1997)
J Natl Cancer Inst.
, vol.89
, Issue.23
, pp. 1789-1796
-
-
Bailey, H.H.1
-
87
-
-
84939567183
-
Pilot study of intravenous melphalan combined with continuous infusion L-S,R-buthionine sulfoximine for children with recurrent neuroblastoma
-
Anderson CP, et al. Pilot study of intravenous melphalan combined with continuous infusion L-S,R-buthionine sulfoximine for children with recurrent neuroblastoma. Pediatr Blood Cancer. 2015;62(10):1739-1746.
-
(2015)
Pediatr Blood Cancer
, vol.62
, Issue.10
, pp. 1739-1746
-
-
Anderson, C.P.1
-
88
-
-
23444435104
-
Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds
-
Witte AB, Anestål K, Jerremalm E, Ehrsson H, Arnér ES. Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds. Free Radic Biol Med. 2005;39(5):696-703.
-
(2005)
Free Radic Biol Med.
, vol.39
, Issue.5
, pp. 696-703
-
-
Witte, A.B.1
Anestål, K.2
Jerremalm, E.3
Ehrsson, H.4
Arnér, E.S.5
-
89
-
-
84925016308
-
Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: A novel synergistic therapeutic approach
-
Kiebala M, et al. Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach. Exp Hematol. 2015;43(2):89-99.
-
(2015)
Exp Hematol
, vol.43
, Issue.2
, pp. 89-99
-
-
Kiebala, M.1
-
90
-
-
67649800278
-
Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase
-
Zahedi Avval F, Holmgren A. Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase. J Biol Chem. 2009;284(13):8233-8240.
-
(2009)
J Biol Chem
, vol.284
, Issue.13
, pp. 8233-8240
-
-
Zahedi Avval, F.1
Holmgren, A.2
-
91
-
-
70349230931
-
Inhibition of glutathione and thioredoxin metabolism enhances sensitivity to perifosine in head and neck cancer cells
-
Simons AL, Parsons AD, Foster KA, Orcutt KP, Fath MA, Spitz DR. Inhibition of glutathione and thioredoxin metabolism enhances sensitivity to perifosine in head and neck cancer cells. J Oncol. 2009;2009:519563.
-
(2009)
J Oncol
, vol.2009
, pp. 519563
-
-
Simons, A.L.1
Parsons, A.D.2
Foster, K.A.3
Orcutt, K.P.4
Fath, M.A.5
Spitz, D.R.6
-
92
-
-
84868286860
-
Susceptibility of human head and neck cancer cells tocombined inhibition of glutathione and thioredoxin metabolism
-
Sobhakumari A, et al. Susceptibility of human head and neck cancer cells tocombined inhibition of glutathione and thioredoxin metabolism. PLoS One. 2012;7(10):e48175.
-
(2012)
PLoS One
, vol.7
, Issue.10
, pp. e48175
-
-
Sobhakumari, A.1
-
93
-
-
84855432506
-
Simultaneous inhibition of glutathione- and thioredoxindependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress
-
Scarbrough PM, Mapuskar KA, Mattson DM, Gius D, Watson WH, Spitz DR. Simultaneous inhibition of glutathione- and thioredoxindependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress. Free Radic Biol Med. 2012;52(2):436-443.
-
(2012)
Free Radic Biol Med.
, vol.52
, Issue.2
, pp. 436-443
-
-
Scarbrough, P.M.1
Mapuskar, K.A.2
Mattson, D.M.3
Gius, D.4
Watson, W.H.5
Spitz, D.R.6
-
94
-
-
84937843579
-
Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells
-
Sachweh MC, et al. Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells. Oncotarget. 2015;6(18):16488-16506.
-
(2015)
Oncotarget
, vol.6
, Issue.18
, pp. 16488-16506
-
-
Sachweh, M.C.1
-
95
-
-
84954047445
-
Auranofin induces mesothelioma cell death through oxidative stress and GSH depletion
-
You BR, Park WH. Auranofin induces mesothelioma cell death through oxidative stress and GSH depletion. Oncol Rep. 2015;35(1):546-551.
-
(2015)
Oncol Rep.
, vol.35
, Issue.1
, pp. 546-551
-
-
You, B.R.1
Park, W.H.2
-
96
-
-
84880096840
-
Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS
-
Shytaj IL, et al. Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS. Retrovirology. 2013;10:71.
-
(2013)
Retrovirology
, vol.10
, pp. 71
-
-
Shytaj, I.L.1
-
97
-
-
0032018639
-
Glutathione and HIV infection: Reduced, or increased oxidized?
-
Staal FJ. Glutathione and HIV infection: reduced, or increased oxidized? Eur J Clin Invest. 1998;28(3):194-196.
-
(1998)
Eur J Clin Invest
, vol.28
, Issue.3
, pp. 194-196
-
-
Staal, F.J.1
-
98
-
-
0025739254
-
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
-
Schreck R, Rieber P, Baeuerle PA. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 1991;10(8):2247-2258.
-
(1991)
EMBO J.
, vol.10
, Issue.8
, pp. 2247-2258
-
-
Schreck, R.1
Rieber, P.2
Baeuerle, P.A.3
-
99
-
-
0030809090
-
Intracellular GSH content and HIV replication in human macrophages
-
Garaci E, et al. Intracellular GSH content and HIV replication in human macrophages. J Leukoc Biol. 1997;62(1):54-59.
-
(1997)
J Leukoc Biol.
, vol.62
, Issue.1
, pp. 54-59
-
-
Garaci, E.1
-
100
-
-
0029743762
-
Effect of N-acetylcysteine(NAC) treatment on HIV-1 infection: A double-blind placebo-controlled trial
-
Akerlund B, Jarstrand C, Lindeke B, Sönnerborg A, Akerblad AC, Rasool O. Effect of N-acetylcysteine(NAC) treatment on HIV-1 infection: a double-blind placebo-controlled trial. Eur J Clin Pharmacol. 1996;50(6):457-461.
-
(1996)
Eur J Clin Pharmacol
, vol.50
, Issue.6
, pp. 457-461
-
-
Akerlund, B.1
Jarstrand, C.2
Lindeke, B.3
Sönnerborg, A.4
Akerblad, A.C.5
Rasool, O.6
-
101
-
-
0032504917
-
Effects of Vitamin E and C supplementation on oxidative stress and viral load in HIVinfected subjects
-
Allard JP, et al. Effects of vitamin E and C supplementation on oxidative stress and viral load in HIVinfected subjects. AIDS. 1998;12(13):1653-1659.
-
(1998)
AIDS
, vol.12
, Issue.13
, pp. 1653-1659
-
-
Allard, J.P.1
-
102
-
-
0033545464
-
Micronutrient supplementation in the AIDS diarrhoea-wasting syndrome in Zambia: A randomized controlled trial
-
Kelly P, Musonda R, Kafwembe E, Kaetano L, Keane E, Farthing M. Micronutrient supplementation in the AIDS diarrhoea-wasting syndrome in Zambia: a randomized controlled trial. AIDS. 1999;13(4):495-500.
-
(1999)
AIDS
, vol.13
, Issue.4
, pp. 495-500
-
-
Kelly, P.1
Musonda, R.2
Kafwembe, E.3
Kaetano, L.4
Keane, E.5
Farthing, M.6
-
103
-
-
84906060948
-
HIV and noncommunicable disease comorbidities in the era of antiretroviral therapy: A vital agenda for research in low- and middle-income country settings
-
Narayan KM, et al. HIV and noncommunicable disease comorbidities in the era of antiretroviral therapy: a vital agenda for research in low- and middle-income country settings. J Acquir Immune Defic Syndr. 2014;67(suppl 1):S2-S7.
-
(2014)
J Acquir Immune Defic Syndr
, vol.67
, pp. S2-S7
-
-
Narayan, K.M.1
-
104
-
-
79954436446
-
+ T-cell memory and HIV persistence: Keeping memory, keeping HIV
-
Chomont N, DaFonseca S, Vandergeeten C, Ancuta P, Sékaly RP. Maintenance of CD4+ T-cell memory and HIV persistence: keeping memory, keeping HIV. Curr Opin HIV AIDS. 2011;6(1):30-36.
-
(2011)
Curr Opin HIV AIDS
, vol.6
, Issue.1
, pp. 30-36
-
-
Chomont, N.1
DaFonseca, S.2
Vandergeeten, C.3
Ancuta, P.4
Sékaly, R.P.5
-
105
-
-
0032953920
-
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
-
Finzi D, et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat Med. 1999;5(5):512-517.
-
(1999)
Nat Med.
, vol.5
, Issue.5
, pp. 512-517
-
-
Finzi, D.1
-
106
-
-
0029863314
-
Activation of the HIV long terminal repeat and viral production by H2O2-vanadate
-
Kazazi F, Koehler JK, Klebanoff SJ. Activation of the HIV long terminal repeat and viral production by H2O2-vanadate. Free Radic Biol Med. 1996;20(6):813-820.
-
(1996)
Free Radic Biol Med.
, vol.20
, Issue.6
, pp. 813-820
-
-
Kazazi, F.1
Koehler, J.K.2
Klebanoff, S.J.3
-
107
-
-
0026030449
-
Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine
-
Kalebic T, Kinter A, Poli G, Anderson ME, Meister A, Fauci AS. Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine. Proc Natl Acad Sci U S A. 1991;88(3):986-990.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, Issue.3
, pp. 986-990
-
-
Kalebic, T.1
Kinter, A.2
Poli, G.3
Anderson, M.E.4
Meister, A.5
Fauci, A.S.6
-
108
-
-
0025834966
-
N-acetylcysteine inhibits latent HIV expression in chronically infected cells
-
Roederer M, Raju PA, Staal FJ, Herzenberg LA, Herzenberg LA. N-acetylcysteine inhibits latent HIV expression in chronically infected cells. AIDS Res Hum Retroviruses. 1991;7(6):563-567.
-
(1991)
AIDS Res Hum Retroviruses
, vol.7
, Issue.6
, pp. 563-567
-
-
Roederer, M.1
Raju, P.A.2
Staal, F.J.3
Herzenberg, L.A.4
Herzenberg, L.A.5
-
109
-
-
0028988078
-
NF-κB transcription factor and human immunodeficiency virus type 1 (HIV-1) activation by methylene blue photosensitization
-
Piret B, Legrand-Poels S, Sappey C, Piette J. NF-κB transcription factor and human immunodeficiency virus type 1 (HIV-1) activation by methylene blue photosensitization. Eur J Biochem. 1995;228(2):447-455.
-
(1995)
Eur J Biochem
, vol.228
, Issue.2
, pp. 447-455
-
-
Piret, B.1
Legrand-Poels, S.2
Sappey, C.3
Piette, J.4
-
110
-
-
59449101108
-
Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells
-
Bosque A, Planelles V. Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells. Blood. 2009;113(1):58-65.
-
(2009)
Blood
, vol.113
, Issue.1
, pp. 58-65
-
-
Bosque, A.1
Planelles, V.2
-
111
-
-
84910624272
-
Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65
-
Shinozaki S, et al. Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65. Sci Signal. 2014;7(351):ra106.
-
(2014)
Sci Signal.
, vol.7
, Issue.351
, pp. 106
-
-
Shinozaki, S.1
-
112
-
-
84879105224
-
+ T cells
-
Lusic M, Marini B, Ali H, Lucic B, Luzzati R, Giacca M. Proximity to PML nuclear bodies regulates HIV-1 latency in CD4+ T cells. Cell Host Microbe. 2013;13(6):665-677.
-
(2013)
Cell Host Microbe
, vol.13
, Issue.6
, pp. 665-677
-
-
Lusic, M.1
Marini, B.2
Ali, H.3
Lucic, B.4
Luzzati, R.5
Giacca, M.6
-
113
-
-
0344980379
-
Nitric oxide modulates HIV-1 replication
-
Mannick JB, et al. Nitric oxide modulates HIV-1 replication. J Acquir Immune Defic Syndr. 1999;22(1):1-9.
-
(1999)
J Acquir Immune Defic Syndr
, vol.22
, Issue.1
, pp. 1-9
-
-
Mannick, J.B.1
-
114
-
-
84931265981
-
Apoptosisinduced activation of HIV-1 in latently infected cell lines
-
Khan SZ, Hand N, Zeichner SL. Apoptosisinduced activation of HIV-1 in latently infected cell lines. Retrovirology. 2015;12:42.
-
(2015)
Retrovirology
, vol.12
, pp. 42
-
-
Khan, S.Z.1
Hand, N.2
Zeichner, S.L.3
-
115
-
-
0142183455
-
B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs
-
Kamio T, et al. B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs. Blood. 2003;102(9):3317-3322.
-
(2003)
Blood
, vol.102
, Issue.9
, pp. 3317-3322
-
-
Kamio, T.1
-
116
-
-
84903203335
-
Mechanisms of action of fludarabine nucleoside against human Raji lymphoma cells
-
Christopherson RI, Mactier S, Almazi JG, Kohnke PL, Best OG, Mulligan SP. Mechanisms of action of fludarabine nucleoside against human Raji lymphoma cells. Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):375-383.
-
(2014)
Nucleosides Nucleotides Nucleic Acids
, vol.33
, Issue.4-6
, pp. 375-383
-
-
Christopherson, R.I.1
Mactier, S.2
Almazi, J.G.3
Kohnke, P.L.4
Best, O.G.5
Mulligan, S.P.6
-
117
-
-
34347268139
-
Involvement of reactive oxygen species in multidrug resistance of a vincristine-selected lymphoblastoma
-
Tsai SY, Sun NK, Lu HP, Cheng ML, Chao CC. Involvement of reactive oxygen species in multidrug resistance of a vincristine-selected lymphoblastoma. Cancer Sci. 2007;98(8):1206-1214.
-
(2007)
Cancer Sci.
, vol.98
, Issue.8
, pp. 1206-1214
-
-
Tsai, S.Y.1
Sun, N.K.2
Lu, H.P.3
Cheng, M.L.4
Chao, C.C.5
-
118
-
-
67649259174
-
Shock and kill effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence
-
Savarino A, et al. "Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence. Retrovirology. 2009;6:52.
-
(2009)
Retrovirology
, vol.6
, pp. 52
-
-
Savarino, A.1
-
119
-
-
60549090253
-
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
-
Hütter G, et al. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med. 2009;360(7):692-698.
-
(2009)
N Engl J Med.
, vol.360
, Issue.7
, pp. 692-698
-
-
Hütter, G.1
-
120
-
-
77954633050
-
HIV persistence and the prospect of long-term drug-free remissions forHIV-infected individuals
-
Trono D, et al. HIV persistence and the prospect of long-term drug-free remissions forHIV-infected individuals. Science. 2010;329(5988):174-180.
-
(2010)
Science
, vol.329
, Issue.5988
, pp. 174-180
-
-
Trono, D.1
-
121
-
-
84880401202
-
Residual immune dysregulation syndrome in treated HIV infection
-
Lederman MM, Funderburg NT, Sekaly RP, Klatt NR, Hunt PW. Residual immune dysregulation syndrome in treated HIV infection. Adv Immunol. 2013;119:51-83.
-
(2013)
Adv Immunol
, vol.119
, pp. 51-83
-
-
Lederman, M.M.1
Funderburg, N.T.2
Sekaly, R.P.3
Klatt, N.R.4
Hunt, P.W.5
-
122
-
-
84935914891
-
Chloroquine and beyond: Exploring anti-rheumatic drugs to reduce immune hyperactivation in HIV/AIDS
-
Savarino A, Shytaj IL. Chloroquine and beyond: exploring anti-rheumatic drugs to reduce immune hyperactivation in HIV/AIDS. Retrovirology. 2015;12:51.
-
(2015)
Retrovirology
, vol.12
, pp. 51
-
-
Savarino, A.1
Shytaj, I.L.2
-
123
-
-
45749134564
-
The anticancer immune response: Indispensable for therapeutic success?
-
Zitvogel L, Apetoh L, Ghiringhelli F, André F, Tesniere A, Kroemer G. The anticancer immune response: indispensable for therapeutic success? J Clin Invest. 2008;118(6):1991-2001.
-
(2008)
J Clin Invest.
, vol.118
, Issue.6
, pp. 1991-2001
-
-
Zitvogel, L.1
Apetoh, L.2
Ghiringhelli, F.3
André, F.4
Tesniere, A.5
Kroemer, G.6
-
124
-
-
33847258674
-
Discovery and development of SAHA as an anticancer agent
-
Marks PA. Discovery and development of SAHA as an anticancer agent. Oncogene. 2007;26(9):1351-1356.
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1351-1356
-
-
Marks, P.A.1
-
125
-
-
19044394312
-
Overview of ribonucleotide reductase inhibitors: An appealing target in anti-tumour therapy
-
Cerqueira NM, Pereira S, Fernandes PA, Ramos MJ. Overview of ribonucleotide reductase inhibitors: an appealing target in anti-tumour therapy. Curr Med Chem. 2005;12(11):1283-1294.
-
(2005)
Curr Med Chem
, vol.12
, Issue.11
, pp. 1283-1294
-
-
Cerqueira, N.M.1
Pereira, S.2
Fernandes, P.A.3
Ramos, M.J.4
-
126
-
-
0032785432
-
Effects of nitric oxide on the induction and differentiation of Th1 cells
-
Niedbala W, Wei XQ, Piedrafita D, Xu D, Liew FY. Effects of nitric oxide on the induction and differentiation of Th1 cells. Eur J Immunol. 1999;29(8):2498-2505.
-
(1999)
Eur J Immunol
, vol.29
, Issue.8
, pp. 2498-2505
-
-
Niedbala, W.1
Wei, X.Q.2
Piedrafita, D.3
Xu, D.4
Liew, F.Y.5
-
127
-
-
79959566034
-
+ regulatory T cell differentiation and potentiate Th1 development
-
Lee SW, Choi H, Eun SY, Fukuyama S, Croft M. Nitric oxide modulates TGF-β-directive signals to suppress Foxp3+ regulatory T cell differentiation and potentiate Th1 development. J Immunol. 2011;186(12):6972-6980.
-
(2011)
J Immunol
, vol.186
, Issue.12
, pp. 6972-6980
-
-
Lee, S.W.1
Choi, H.2
Eun, S.Y.3
Fukuyama, S.4
Croft, M.5
-
128
-
-
4344625883
-
A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells
-
Friesen C, Kiess Y, Debatin KM. A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells. Cell Death Differ. 2004;11(suppl 1):S73-S85.
-
(2004)
Cell Death Differ.
, vol.11
, pp. S73-S85
-
-
Friesen, C.1
Kiess, Y.2
Debatin, K.M.3
-
129
-
-
84928718905
-
Post-treatment control of HIV infection
-
Conway JM, Perelson AS. Post-treatment control of HIV infection. Proc Natl Acad Sci U S A. 2015;112(17):5467-5472.
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, Issue.17
, pp. 5467-5472
-
-
Conway, J.M.1
Perelson, A.S.2
-
130
-
-
84942369533
-
Cell-mediated anti-Gag immunity in pharmacologically induced functional cure of simian AIDS: A 'bottleneck effect'?
-
Shytaj IL, Savarino A. Cell-mediated anti-Gag immunity in pharmacologically induced functional cure of simian AIDS: a 'bottleneck effect'? J Med Primatol. 2015;44(5):227-240.
-
(2015)
J Med Primatol
, vol.44
, Issue.5
, pp. 227-240
-
-
Shytaj, I.L.1
Savarino, A.2
-
131
-
-
84922764937
-
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
-
Deng K, et al. Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations. Nature. 2015;517(7534):381-385.
-
(2015)
Nature
, vol.517
, Issue.7534
, pp. 381-385
-
-
Deng, K.1
-
132
-
-
79953272280
-
Human immunodeficiency virus infection and hodgkin's Lymphoma in South Africa: An emerging problem
-
Patel M, Philip V, Fazel F. Human Immunodeficiency Virus Infection and Hodgkin's Lymphoma in South Africa: an emerging problem. Adv Hematol. 2011;2011:578163.
-
(2011)
Adv Hematol
, vol.2011
, pp. 578163
-
-
Patel, M.1
Philip, V.2
Fazel, F.3
-
133
-
-
84896701770
-
Malignancies in South African children with HIV
-
Davidson A, et al. Malignancies in South African children with HIV. J Pediatr Hematol Oncol. 2014;36(2):111-117.
-
(2014)
J Pediatr Hematol Oncol
, vol.36
, Issue.2
, pp. 111-117
-
-
Davidson, A.1
-
134
-
-
84864051807
-
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model
-
Shytaj IL, et al. A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. PLoS Pathog. 2012;8(6):e1002774.
-
(2012)
PLoS Pathog
, vol.8
, Issue.6
, pp. e1002774
-
-
Shytaj, I.L.1
-
135
-
-
84866150865
-
Nonhuman primate models for HIV cure research
-
Apetrei C, Pandrea I, Mellors JW. Nonhuman primate models for HIV cure research. PLoS Pathog. 2012;8(8):e1002892.
-
(2012)
PLoS Pathog
, vol.8
, Issue.8
, pp. e1002892
-
-
Apetrei, C.1
Pandrea, I.2
Mellors, J.W.3
|