Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose

Journal of Biological Chemistry

Volumn 287, Issue 45, 2012, Pages 38210-38219

  Du, Yatao ^a   Zhang, Huihui ^a   Lu, Jun ^a   Holmgren, Arne ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURVIVAL; GLUTATHIONES; REDOX STATE; REDUCTANTS; THIOREDOXIN REDUCTASE; THIOREDOXINS;

CELL DEATH; ENZYMES;

PEPTIDES;

GLUTAREDOXIN; GLUTATHIONE; GLUTATHIONE REDUCTASE; REACTIVE OXYGEN METABOLITE; THIOREDOXIN 1; THIOREDOXIN 2; THIOREDOXIN REDUCTASE 1; THIOREDOXIN REDUCTASE 2;

ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME METABOLISM; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; AURANOFIN; AUROTHIOGLUCOSE; AZOLES; BLOTTING, WESTERN; BUTHIONINE SULFOXIMINE; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; GLUTAREDOXINS; GLUTATHIONE; HCT116 CELLS; HELA CELLS; HUMANS; MODELS, BIOLOGICAL; MUTATION; ORGANOSELENIUM COMPOUNDS; OXIDATION-REDUCTION; RATS; REACTIVE OXYGEN SPECIES; THIOREDOXIN REDUCTASE 1; THIOREDOXINS; TIME FACTORS;

EID: 84868328588     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.392225     Document Type: Article

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