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Volumn 44, Issue 5, 2015, Pages 227-240

Cell-mediated anti-Gag immunity in pharmacologically induced functional cure of simian AIDS: A 'bottleneck effect'?

Author keywords

Auranofin; Bottleneck effect; Buthionine sulfoximine; Conserved sequences; Entropy; Gag

Indexed keywords

AURANOFIN; BUTHIONINE SULFOXIMINE; GAG PROTEIN; ANTIRETROVIRUS AGENT;

EID: 84942369533     PISSN: 00472565     EISSN: 16000684     Source Type: Journal    
DOI: 10.1111/jmp.12176     Document Type: Article
Times cited : (4)

References (93)
  • 2
    • 33749474469 scopus 로고    scopus 로고
    • Hitting HIV where it hurts: an alternative approach to HIV vaccine design
    • Altfeld M, Allen TM: Hitting HIV where it hurts: an alternative approach to HIV vaccine design. Trends Immunol 2006; 27:504-10.
    • (2006) Trends Immunol , vol.27 , pp. 504-510
    • Altfeld, M.1    Allen, T.M.2
  • 6
    • 0028041344 scopus 로고
    • Virus-specific CD8 + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • Borrow P, Lewicki H, Hahn BH, Shaw GM, Oldstone MB: Virus-specific CD8 + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994; 68:6103-10.
    • (1994) J Virol , vol.68 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, G.M.4    Oldstone, M.B.5
  • 9
    • 34548133728 scopus 로고    scopus 로고
    • Predicting functionally important residues from sequence conservation
    • Capra JA, Singh M: Predicting functionally important residues from sequence conservation. Bioinformatics 2007; 23:1875-82.
    • (2007) Bioinformatics , vol.23 , pp. 1875-1882
    • Capra, J.A.1    Singh, M.2
  • 11
    • 0034043778 scopus 로고    scopus 로고
    • Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis
    • Castresana J: Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. Mol Biol Evol 2000; 17:540-52.
    • (2000) Mol Biol Evol , vol.17 , pp. 540-552
    • Castresana, J.1
  • 12
    • 34250155317 scopus 로고    scopus 로고
    • Mutations in capsid major homology region affect assembly and membrane affinity of HIV-1 Gag
    • Chang YF, Wang SM, Huang KJ, Wang CT: Mutations in capsid major homology region affect assembly and membrane affinity of HIV-1 Gag. J Mol Biol 2007; 370:585-97.
    • (2007) J Mol Biol , vol.370 , pp. 585-597
    • Chang, Y.F.1    Wang, S.M.2    Huang, K.J.3    Wang, C.T.4
  • 13
    • 23844476202 scopus 로고    scopus 로고
    • Numbering positions in SIV relative to SIVMM239
    • Kuiken, Hahn, Marx, McCutchan, Mellors, Wolinsky & Korber (eds). Los Alamos, N.Mex. USA: Los Alamos National Laboratory: Theoretical Biology and Biophysics Group
    • Charles Calef JM, O'Connor DH, Watkins DI, Korber B: Numbering positions in SIV relative to SIVMM239. In: HIV Sequence Compendium. Kuiken, Hahn, Marx, McCutchan, Mellors, Wolinsky & Korber (eds). Los Alamos, N.Mex. USA: Los Alamos National Laboratory: Theoretical Biology and Biophysics Group, 2001; 171-81.
    • (2001) HIV Sequence Compendium , pp. 171-181
    • Charles Calef, J.M.1    O'Connor, D.H.2    Watkins, D.I.3    Korber, B.4
  • 23
    • 0027220120 scopus 로고
    • Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein
    • Dorfman T, Luban J, Goff SP, Haseltine WA, Göttlinger HG: Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein. J Virol 1993; 67:6159-69.
    • (1993) J Virol , vol.67 , pp. 6159-6169
    • Dorfman, T.1    Luban, J.2    Goff, S.P.3    Haseltine, W.A.4    Göttlinger, H.G.5
  • 25
    • 79551683191 scopus 로고    scopus 로고
    • Structure of the HIV-1 full-length capsid protein in a conformationally trapped unassembled state induced by small-molecule binding
    • Du S, Betts L, Yang R, Shi H, Concel J, Ahn J, Aiken C, Zhang P, Yeh JI: Structure of the HIV-1 full-length capsid protein in a conformationally trapped unassembled state induced by small-molecule binding. J Mol Biol 2011; 406:371-86.
    • (2011) J Mol Biol , vol.406 , pp. 371-386
    • Du, S.1    Betts, L.2    Yang, R.3    Shi, H.4    Concel, J.5    Ahn, J.6    Aiken, C.7    Zhang, P.8    Yeh, J.I.9
  • 26
    • 3042666256 scopus 로고    scopus 로고
    • MUSCLE: multiple sequence alignment with high accuracy and high throughput
    • Edgar RC: MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res 2004; 32:1792-7.
    • (2004) Nucleic Acids Res , vol.32 , pp. 1792-1797
    • Edgar, R.C.1
  • 27
    • 0036171258 scopus 로고    scopus 로고
    • Magnitude of functional CD8 + T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma
    • Edwards BH, Bansal A, Sabbaj S, Bakari J, Mulligan MJ, Goepfert PA: Magnitude of functional CD8 + T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma. J Virol 2002; 76:2298-305.
    • (2002) J Virol , vol.76 , pp. 2298-2305
    • Edwards, B.H.1    Bansal, A.2    Sabbaj, S.3    Bakari, J.4    Mulligan, M.J.5    Goepfert, P.A.6
  • 30
    • 84942378865 scopus 로고    scopus 로고
    • Functional cure post-therapeutic vaccination of SIV-infected macaques correlates with broader T specificity and function and lower expression of inflammatory cytokines
    • Oregon, Nov 11-14, 2014 (Oral presentation).
    • Fuller D, Narendran A, Rajakumar P, Stagnar C, Murphey-Corb M: Functional cure post-therapeutic vaccination of SIV-infected macaques correlates with broader T specificity and function and lower expression of inflammatory cytokines. 32st Annual Symposium on Nonhuman Primate Models for AIDS Portland, Oregon, Nov 11-14, 2014 (Oral presentation).
    • 32st Annual Symposium on Nonhuman Primate Models for AIDS Portland
    • Fuller, D.1    Narendran, A.2    Rajakumar, P.3    Stagnar, C.4    Murphey-Corb, M.5
  • 32
    • 58149500187 scopus 로고    scopus 로고
    • A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution
    • Gifford RJ, Katzourakis A, Tristem M, Pybus OG, Winters M, Shafer RW: A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution. Proc Natl Acad Sci USA 2008; 105:20362-7.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 20362-20367
    • Gifford, R.J.1    Katzourakis, A.2    Tristem, M.3    Pybus, O.G.4    Winters, M.5    Shafer, R.W.6
  • 33
    • 0027965585 scopus 로고
    • CD8 + lymphocyte activation at human immunodeficiency virus type 1 seroconversion: development of HLA-DR+ CD38- CD8 + cells is associated with subsequent stable CD4 + cell levels. The Multicenter AIDS Cohort Study Group
    • Giorgi JV, Ho HN, Hirji K, Chou CC, Hultin LE, O'Rourke S, Park L, Margolick JB, Ferbas J, Phair JP: CD8 + lymphocyte activation at human immunodeficiency virus type 1 seroconversion: development of HLA-DR+ CD38- CD8 + cells is associated with subsequent stable CD4 + cell levels. The Multicenter AIDS Cohort Study Group. J Infect Dis 1994; 170:775-81.
    • (1994) J Infect Dis , vol.170 , pp. 775-781
    • Giorgi, J.V.1    Ho, H.N.2    Hirji, K.3    Chou, C.C.4    Hultin, L.E.5    O'Rourke, S.6    Park, L.7    Margolick, J.B.8    Ferbas, J.9    Phair, J.P.10
  • 34
    • 33749430312 scopus 로고    scopus 로고
    • The call of the wild: what can be learned from studies of SIV infection of natural hosts?
    • Leitner, Foley, Hahn, Marx, McCutchan, Mellors, Wolinsky, Korber (eds). Los Alamos, NM: Los Alamos National Laboratory
    • Gordon S, Pandrea I, Dunham R, Apetrei C, Silvestri G: The call of the wild: what can be learned from studies of SIV infection of natural hosts? In: HIV Sequence Compendium 2004 Theoretical Biology and Biophysics Group. Leitner, Foley, Hahn, Marx, McCutchan, Mellors, Wolinsky, Korber (eds). Los Alamos, NM: Los Alamos National Laboratory, 2004; 2-29.
    • (2004) HIV Sequence Compendium 2004 Theoretical Biology and Biophysics Group , pp. 2-29
    • Gordon, S.1    Pandrea, I.2    Dunham, R.3    Apetrei, C.4    Silvestri, G.5
  • 37
    • 0018666729 scopus 로고
    • Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
    • Griffith OW, Meister A: Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J Biol Chem 1979; 254:7558-60.
    • (1979) J Biol Chem , vol.254 , pp. 7558-7560
    • Griffith, O.W.1    Meister, A.2
  • 38
    • 0031473847 scopus 로고    scopus 로고
    • SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling
    • Guex N, Peitsch MC: SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 1997; 18:2714-23.
    • (1997) Electrophoresis , vol.18 , pp. 2714-2723
    • Guex, N.1    Peitsch, M.C.2
  • 39
    • 27344440132 scopus 로고    scopus 로고
    • Conservation and relative importance of residues across protein-protein interfaces
    • Guharoy M, Chakrabarti P: Conservation and relative importance of residues across protein-protein interfaces. Proc Natl Acad Sci USA 2005; 102:15447-52.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15447-15452
    • Guharoy, M.1    Chakrabarti, P.2
  • 40
    • 77950806408 scopus 로고    scopus 로고
    • New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0
    • Guindon S, Dufayard JF, Lefort V, Anisimova M, Hordijk W, Gascuel O: New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst Biol 2010; 59:307-21.
    • (2010) Syst Biol , vol.59 , pp. 307-321
    • Guindon, S.1    Dufayard, J.F.2    Lefort, V.3    Anisimova, M.4    Hordijk, W.5    Gascuel, O.6
  • 42
  • 43
    • 84935020844 scopus 로고    scopus 로고
    • Endogenous lentivirus in Malayan colugo (Galeopterus variegatus), a close relative of primates
    • Hron T, Fábryová H, Pa Es J, Elleder D: Endogenous lentivirus in Malayan colugo (Galeopterus variegatus), a close relative of primates. Retrovirology 2014; 11:84.
    • (2014) Retrovirology , vol.11 , pp. 84
    • Hron, T.1    Fábryová, H.2    Pa Es, J.3    Elleder, D.4
  • 44
    • 84875955713 scopus 로고    scopus 로고
    • Dissecting the dynamics of HIV-1 protein sequence diversity
    • Hu Y, Tan PT, Tan TW, August JT, Khan AM: Dissecting the dynamics of HIV-1 protein sequence diversity. PLoS ONE 2013; 8:e59994.
    • (2013) PLoS ONE , vol.8 , pp. e59994
    • Hu, Y.1    Tan, P.T.2    Tan, T.W.3    August, J.T.4    Khan, A.M.5
  • 51
    • 1642452921 scopus 로고    scopus 로고
    • Automated selection of positions determining functional specificity of proteins by comparative analysis of orthologous groups in protein families
    • Kalinina OV, Mironov AA, Gelfand MS, Rakhmaninova AB: Automated selection of positions determining functional specificity of proteins by comparative analysis of orthologous groups in protein families. Protein Sci 2004; 13:443-56.
    • (2004) Protein Sci , vol.13 , pp. 443-456
    • Kalinina, O.V.1    Mironov, A.A.2    Gelfand, M.S.3    Rakhmaninova, A.B.4
  • 53
    • 0030732128 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 (HIV-1)-specific T cell responses correlate with control of acute HIV-1 infection in macaques
    • Kent SJ, Woodward A, Zhao A: Human immunodeficiency virus type 1 (HIV-1)-specific T cell responses correlate with control of acute HIV-1 infection in macaques. J Infect Dis 1997; 176:1188-97.
    • (1997) J Infect Dis , vol.176 , pp. 1188-1197
    • Kent, S.J.1    Woodward, A.2    Zhao, A.3
  • 56
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, Borkowsky W, Farthing C, Ho DD: Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 1994; 68:4650-5.
    • (1994) J Virol , vol.68 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3    Andrews, C.A.4    McLeod, G.5    Borkowsky, W.6    Farthing, C.7    Ho, D.D.8
  • 59
    • 33747150197 scopus 로고    scopus 로고
    • Protein binding site prediction using an empirical scoring function
    • Liang S, Zhang C, Liu S, Zhou Y: Protein binding site prediction using an empirical scoring function. Nucleic Acids Res 2006; 34:3698-707.
    • (2006) Nucleic Acids Res , vol.34 , pp. 3698-3707
    • Liang, S.1    Zhang, C.2    Liu, S.3    Zhou, Y.4
  • 61
    • 0028342554 scopus 로고
    • Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis
    • Mammano F, Ohagen A, Höglund S, Göttlinger HG: Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis. J Virol 1994; 68:4927-36.
    • (1994) J Virol , vol.68 , pp. 4927-4936
    • Mammano, F.1    Ohagen, A.2    Höglund, S.3    Göttlinger, H.G.4
  • 64
    • 0037321597 scopus 로고    scopus 로고
    • Expression of the major histocompatibility complex class I molecule Mamu-A*01 is associated with control of simian immunodeficiency virus SIVmac239 replication
    • Mothé BR, Weinfurter J, Wang C, Rehrauer W, Wilson N, Allen TM, Allison DB, Watkins DI: Expression of the major histocompatibility complex class I molecule Mamu-A*01 is associated with control of simian immunodeficiency virus SIVmac239 replication. J Virol 2003; 77:2736-40.
    • (2003) J Virol , vol.77 , pp. 2736-2740
    • Mothé, B.R.1    Weinfurter, J.2    Wang, C.3    Rehrauer, W.4    Wilson, N.5    Allen, T.M.6    Allison, D.B.7    Watkins, D.I.8
  • 67
    • 3042816008 scopus 로고    scopus 로고
    • Overview of primate lentiviruses and their evolution in non-human primates in Africa
    • Kuiken, Foley, Freed, Hahn, Korber, Marx, McCutchan, Mellors & Wolinsky (eds). Los Alamos, N.Mex. USA: Los Alamos National Laboratory: Theoretical Biology and Biophysics Group
    • Peeters M, Courgnaud V: Overview of primate lentiviruses and their evolution in non-human primates in Africa. In: HIV Sequence Compendium. Kuiken, Foley, Freed, Hahn, Korber, Marx, McCutchan, Mellors & Wolinsky (eds). Los Alamos, N.Mex. USA: Los Alamos National Laboratory: Theoretical Biology and Biophysics Group, 2002; 2-23.
    • (2002) HIV Sequence Compendium , pp. 2-23
    • Peeters, M.1    Courgnaud, V.2
  • 68
    • 10044227534 scopus 로고    scopus 로고
    • Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope
    • Peyerl FW, Bazick HS, Newberg MH, Barouch DH, Sodroski J, Letvin NL: Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope. J Virol 2004; 78:13901-10.
    • (2004) J Virol , vol.78 , pp. 13901-13910
    • Peyerl, F.W.1    Bazick, H.S.2    Newberg, M.H.3    Barouch, D.H.4    Sodroski, J.5    Letvin, N.L.6
  • 69
    • 0042026307 scopus 로고    scopus 로고
    • Oxidative stress impairs intracellular events involved in antigen processing and presentation to T cells
    • Preynat-Seauve O, Coudurier S, Favier A, Marche PN, Villiers C: Oxidative stress impairs intracellular events involved in antigen processing and presentation to T cells. Cell Stress Chaperones 2003; 8:162-71.
    • (2003) Cell Stress Chaperones , vol.8 , pp. 162-171
    • Preynat-Seauve, O.1    Coudurier, S.2    Favier, A.3    Marche, P.N.4    Villiers, C.5
  • 70
    • 84925498076 scopus 로고    scopus 로고
    • Auranofin: repurposing an old drug for a golden new age
    • Roder C, Thomson MJ: Auranofin: repurposing an old drug for a golden new age. Drugs R D. 2015; 15:13-20.
    • (2015) Drugs R D. , vol.15 , pp. 13-20
    • Roder, C.1    Thomson, M.J.2
  • 72
    • 37348999199 scopus 로고    scopus 로고
    • HIV-1 group M conserved elements vaccine
    • Review.
    • Rolland M, Nickle DC, Mullins JI: HIV-1 group M conserved elements vaccine. PLoS Pathog 2007; 3:e157. Review.
    • (2007) PLoS Pathog , vol.3 , pp. e157
    • Rolland, M.1    Nickle, D.C.2    Mullins, J.I.3
  • 74
    • 67649259174 scopus 로고    scopus 로고
    • "Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence
    • Savarino A, Mai A, Norelli S, El Daker S, Valente S, Rotili D, Altucci L, Palamara AT, Garaci E: "Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence. Retrovirology 2009; 6:52.
    • (2009) Retrovirology , vol.6 , pp. 52
    • Savarino, A.1    Mai, A.2    Norelli, S.3    El Daker, S.4    Valente, S.5    Rotili, D.6    Altucci, L.7    Palamara, A.T.8    Garaci, E.9
  • 77
    • 0038675537 scopus 로고    scopus 로고
    • Conserved residue clustering and protein structure prediction
    • Schueler-Furman O, Baker D: Conserved residue clustering and protein structure prediction. Proteins 2003; 52:225-35.
    • (2003) Proteins , vol.52 , pp. 225-235
    • Schueler-Furman, O.1    Baker, D.2
  • 79
    • 84940644968 scopus 로고
    • A mathematical theory of communication
    • Shannon CE: A mathematical theory of communication. Bell Syst Tech J 1948; 27:379-423.
    • (1948) Bell Syst Tech J , vol.27 , pp. 379-423
    • Shannon, C.E.1
  • 85
    • 84866182030 scopus 로고    scopus 로고
    • Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following simian immunodeficiency virus challenges of vaccinated rhesus monkeys
    • Stephenson KE, Li H, Walker BD, Michael NL, Barouch DH: Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following simian immunodeficiency virus challenges of vaccinated rhesus monkeys. J Virol 2012; 86:9583-9.
    • (2012) J Virol , vol.86 , pp. 9583-9589
    • Stephenson, K.E.1    Li, H.2    Walker, B.D.3    Michael, N.L.4    Barouch, D.H.5
  • 87
    • 0027437490 scopus 로고
    • The interaction of auranofin and buthionine sulfoximine blocks activation of human peripheral T lymphocytes
    • Vint IA, Chain BM, Foreman JC: The interaction of auranofin and buthionine sulfoximine blocks activation of human peripheral T lymphocytes. Cell Immunol 1993; 152:152-61.
    • (1993) Cell Immunol , vol.152 , pp. 152-161
    • Vint, I.A.1    Chain, B.M.2    Foreman, J.C.3
  • 88
    • 0037404501 scopus 로고    scopus 로고
    • Functional surfaces of the human immunodeficiency virus type 1 capsid protein
    • von Schwedler UK, Stray KM, Garrus JE, Sundquist WI: Functional surfaces of the human immunodeficiency virus type 1 capsid protein. J Virol 2003; 77:5439-50.
    • (2003) J Virol , vol.77 , pp. 5439-5450
    • von Schwedler, U.K.1    Stray, K.M.2    Garrus, J.E.3    Sundquist, W.I.4
  • 91
    • 0036340475 scopus 로고    scopus 로고
    • Clustering patterns of CTL epitopes in HIV-1 proteins reveal imprints of immune evasion on HIV-1 global variation
    • Yusim K, Kesmir C, Addo MM, Altfeld M, Gaschen B, Chigaev A, Detours V, Korber BT: Clustering patterns of CTL epitopes in HIV-1 proteins reveal imprints of immune evasion on HIV-1 global variation. J Virol 2002; 76:8757-68.
    • (2002) J Virol , vol.76 , pp. 8757-8768
    • Yusim, K.1    Kesmir, C.2    Addo, M.M.3    Altfeld, M.4    Gaschen, B.5    Chigaev, A.6    Detours, V.7    Korber, B.T.8


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