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Volumn 112, Issue 17, 2015, Pages 5467-5472

Post-treatment control of HIV infection

Author keywords

HIV latency; HIV viral rebound; Immune exhaustion; Mathematical modeling

Indexed keywords

ANTIRETROVIRUS AGENT; VIRUS RNA;

EID: 84928718905     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1419162112     Document Type: Article
Times cited : (160)

References (72)
  • 1
    • 84875985311 scopus 로고    scopus 로고
    • Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study
    • Sáez-Cirión A, et al.; ANRS VISCONTI Study Group (2013) Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog 9(3):e1003211.
    • (2013) PLoS Pathog , vol.9 , Issue.3 , pp. e1003211
    • Sáez-Cirión, A.1
  • 2
    • 84865717158 scopus 로고    scopus 로고
    • HIV-1 control after transient antiretroviral treatment initiated in primary infection: Role of patient characteristics and effect of therapy
    • Goujard C, et al.; ANRS CO6 PRIMO Study Group (2012) HIV-1 control after transient antiretroviral treatment initiated in primary infection: Role of patient characteristics and effect of therapy. Antivir Ther 17(6):1001-1009.
    • (2012) Antivir Ther , vol.17 , Issue.6 , pp. 1001-1009
    • Goujard, C.1
  • 3
    • 82655170576 scopus 로고    scopus 로고
    • Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy
    • Salgado M, et al. (2011) Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy. Retrovirology 8:97.
    • (2011) Retrovirology , vol.8 , pp. 97
    • Salgado, M.1
  • 4
    • 84928752259 scopus 로고    scopus 로고
    • General Hospital reveals fourteen years of HIV functional cure: The case of the 'Toulon Patient'
    • August 5, Available at article.wn.com/view/2014/08/05/General-Hospital-R
    • Lafeuillade A (August 5, 2014) General Hospital reveals fourteen years of HIV functional cure: The case of the 'Toulon Patient'. PR Newswire. Available at article.wn.com/view/2014/08/05/General-Hospital-Reveals-Fourteen-Years-of-HIV-Functional-Cu/.
    • (2014) PR Newswire
    • Lafeuillade, A.1
  • 5
    • 84886401909 scopus 로고    scopus 로고
    • Duration of HIV-1 viral suppression on cessation of antiretroviral therapy in primary infection correlates with time on therapy
    • Stöhr W, et al. (2013) Duration of HIV-1 viral suppression on cessation of antiretroviral therapy in primary infection correlates with time on therapy. PLoS ONE 8(10):e78287.
    • (2013) PLoS ONE , vol.8 , Issue.10 , pp. e78287
    • Stöhr, W.1
  • 6
    • 25444471257 scopus 로고    scopus 로고
    • HIV controllers: A homogeneous group of HIV-1-infected patients with spontaneous control of viral replication
    • Lambotte O, et al.; SEROCO-HEMOCO Study Group (2005) HIV controllers: A homogeneous group of HIV-1-infected patients with spontaneous control of viral replication. Clin Infect Dis 41(7):1053-1056.
    • (2005) Clin Infect Dis , vol.41 , Issue.7 , pp. 1053-1056
    • Lambotte, O.1
  • 7
    • 70449657764 scopus 로고    scopus 로고
    • Elucidating the elite: Mechanisms of control in HIV-1 infection
    • O'Connell KA, Bailey JR, Blankson JN (2009) Elucidating the elite: Mechanisms of control in HIV-1 infection. Trends Pharmacol Sci 30(12):631-637.
    • (2009) Trends Pharmacol Sci , vol.30 , Issue.12 , pp. 631-637
    • O'Connell, K.A.1    Bailey, J.R.2    Blankson, J.N.3
  • 8
    • 73549099347 scopus 로고    scopus 로고
    • Effector mechanisms in HIV-1 infected elite controllers: Highly active immune responses?
    • Blankson JN (2010) Effector mechanisms in HIV-1 infected elite controllers: Highly active immune responses? Antiviral Res 85(1):295-302.
    • (2010) Antiviral Res , vol.85 , Issue.1 , pp. 295-302
    • Blankson, J.N.1
  • 9
    • 35748948369 scopus 로고    scopus 로고
    • Elite control of HIV infection: Implications for vaccines and treatment
    • Walker BD (2007) Elite control of HIV infection: Implications for vaccines and treatment. Top HIV Med 15(4):134-136.
    • (2007) Top HIV Med , vol.15 , Issue.4 , pp. 134-136
    • Walker, B.D.1
  • 10
    • 34249852256 scopus 로고    scopus 로고
    • HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
    • Sáez-Cirión A, et al.; Agence Nationale de Recherches sur le Sida EP36 HIV Controllers Study Group (2007) HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype. Proc Natl Acad Sci USA 104(16):6776-6781.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.16 , pp. 6776-6781
    • Sáez-Cirión, A.1
  • 11
    • 72849130314 scopus 로고    scopus 로고
    • Clinical outcomes of elite controllers, viremic controllers, and long-term nonprogressors in the US Department of Defense HIV natural history study
    • Okulicz JF, et al.; Infectious Disease Clinical Research Program (IDCRP) HIV Working Group (2009) Clinical outcomes of elite controllers, viremic controllers, and long-term nonprogressors in the US Department of Defense HIV natural history study. J Infect Dis 200(11):1714-1723.
    • (2009) J Infect Dis , vol.200 , Issue.11 , pp. 1714-1723
    • Okulicz, J.F.1
  • 12
    • 67651087476 scopus 로고    scopus 로고
    • Prevalence and comparative characteristics of long-term nonprogressors and HIV controller patients in the French Hospital Database on HIV
    • Grabar S, et al. (2009) Prevalence and comparative characteristics of long-term nonprogressors and HIV controller patients in the French Hospital Database on HIV. AIDS 23(9):1163-1169.
    • (2009) AIDS , vol.23 , Issue.9 , pp. 1163-1169
    • Grabar, S.1
  • 13
    • 62249095476 scopus 로고    scopus 로고
    • The challenge of finding a cure for HIV infection
    • Richman DD, et al. (2009) The challenge of finding a cure for HIV infection. Science 323(5919):1304-1307.
    • (2009) Science , vol.323 , Issue.5919 , pp. 1304-1307
    • Richman, D.D.1
  • 14
    • 68349139711 scopus 로고    scopus 로고
    • HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
    • Chomont N, et al. (2009) HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med 15(8):893-900.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 893-900
    • Chomont, N.1
  • 15
    • 0032555117 scopus 로고    scopus 로고
    • Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection
    • Chun TW, et al. (1998) Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection. Proc Natl Acad Sci USA 95(15):8869-8873.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.15 , pp. 8869-8873
    • Chun, T.W.1
  • 16
    • 84859250847 scopus 로고    scopus 로고
    • Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection
    • Ananworanich J, et al.; RV254/SEARCH 010 Study Group (2012) Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. PLoS ONE 7(3):e33948.
    • (2012) PLoS ONE , vol.7 , Issue.3 , pp. e33948
    • Ananworanich, J.1
  • 17
    • 84905565097 scopus 로고    scopus 로고
    • Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys
    • Whitney JB, et al. (2014) Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys. Nature 512(7512):74-77.
    • (2014) Nature , vol.512 , Issue.7512 , pp. 74-77
    • Whitney, J.B.1
  • 18
    • 0030913366 scopus 로고    scopus 로고
    • Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
    • Chun TW, et al. (1997) Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387(6629):183-188.
    • (1997) Nature , vol.387 , Issue.6629 , pp. 183-188
    • Chun, T.W.1
  • 19
    • 84873472629 scopus 로고    scopus 로고
    • Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies
    • Eriksson S, et al. (2013) Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. PLoS Pathog 9(2):e1003174.
    • (2013) PLoS Pathog , vol.9 , Issue.2 , pp. e1003174
    • Eriksson, S.1
  • 20
    • 0038579210 scopus 로고    scopus 로고
    • Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
    • Siliciano JD, et al. (2003) Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med 9(6):727-728.
    • (2003) Nat Med , vol.9 , Issue.6 , pp. 727-728
    • Siliciano, J.D.1
  • 21
    • 0346220188 scopus 로고    scopus 로고
    • Enumeration of latently infected CD4+ T cells from HIV-1-infected patients using an HIV-1 antigen ELISPOT assay
    • Fondère J-M, et al. (2004) Enumeration of latently infected CD4+ T cells from HIV-1-infected patients using an HIV-1 antigen ELISPOT assay. J Clin Virol 29(1):33-38.
    • (2004) J Clin Virol , vol.29 , Issue.1 , pp. 33-38
    • Fondère, J.-M.1
  • 22
    • 84886769508 scopus 로고    scopus 로고
    • Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure
    • Ho YC, et al. (2013) Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell 155(3):540-551.
    • (2013) Cell , vol.155 , Issue.3 , pp. 540-551
    • Ho, Y.C.1
  • 23
    • 0033984045 scopus 로고    scopus 로고
    • The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy
    • Ramratnam B, et al. (2000) The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy. Nat Med 6(1):82-85.
    • (2000) Nat Med , vol.6 , Issue.1 , pp. 82-85
    • Ramratnam, B.1
  • 24
    • 79955550951 scopus 로고    scopus 로고
    • A stochastic model of latently infected cell reactivation and viral blip generation in treated HIV patients
    • Conway JM, Coombs D (2011) A stochastic model of latently infected cell reactivation and viral blip generation in treated HIV patients. PLOS Comput Biol 7(4):e1002033.
    • (2011) PLOS Comput Biol , vol.7 , Issue.4 , pp. e1002033
    • Conway, J.M.1    Coombs, D.2
  • 25
    • 73449117263 scopus 로고    scopus 로고
    • Modeling latently infected cell activation: Viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy
    • Rong L, Perelson AS (2009) Modeling latently infected cell activation: Viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy. PLOS Comput Biol 5(10):e1000533.
    • (2009) PLOS Comput Biol , vol.5 , Issue.10 , pp. e1000533
    • Rong, L.1    Perelson, A.S.2
  • 26
    • 68949196315 scopus 로고    scopus 로고
    • Modeling HIV persistence, the latent reservoir, and viral blips
    • Rong L, Perelson AS (2009) Modeling HIV persistence, the latent reservoir, and viral blips. J Theor Biol 260(2):308-331.
    • (2009) J Theor Biol , vol.260 , Issue.2 , pp. 308-331
    • Rong, L.1    Perelson, A.S.2
  • 27
    • 84876411341 scopus 로고    scopus 로고
    • Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts
    • Hocqueloux L, et al.; AC32 (Coordinated Action on HIV Reservoirs) of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) (2013) Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts. J Antimicrob Chemother 68(5):1169-1178.
    • (2013) J Antimicrob Chemother , vol.68 , Issue.5 , pp. 1169-1178
    • Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS)1    Hocqueloux, L.2
  • 28
    • 0041828179 scopus 로고    scopus 로고
    • Dynamics of HIV viremia and antibody seroconversion in plasma donors: Implications for diagnosis and staging of primary HIV infection
    • Fiebig EW, et al. (2003) Dynamics of HIV viremia and antibody seroconversion in plasma donors: Implications for diagnosis and staging of primary HIV infection. AIDS 17(13):1871-1879.
    • (2003) AIDS , vol.17 , Issue.13 , pp. 1871-1879
    • Fiebig, E.W.1
  • 29
    • 44649102135 scopus 로고    scopus 로고
    • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
    • Keele BF, et al. (2008) Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc Natl Acad Sci USA 105(21):7552-7557.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.21 , pp. 7552-7557
    • Keele, B.F.1
  • 30
    • 84864051807 scopus 로고    scopus 로고
    • A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model
    • Shytaj IL, et al. (2012) A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. PLoS Pathog 8(6):e1002774.
    • (2012) PLoS Pathog , vol.8 , Issue.6 , pp. e1002774
    • Shytaj, I.L.1
  • 31
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    • Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD (1996) HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time. Science 271(5255):1582-1586.
    • (1996) Science , vol.271 , Issue.5255 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 32
    • 0030952479 scopus 로고    scopus 로고
    • Decay characteristics of HIV-1-infected compartments during combination therapy
    • Perelson AS, et al. (1997) Decay characteristics of HIV-1-infected compartments during combination therapy. Nature 387(6629):188-191.
    • (1997) Nature , vol.387 , Issue.6629 , pp. 188-191
    • Perelson, A.S.1
  • 34
    • 33847299097 scopus 로고    scopus 로고
    • Estimation and prediction with HIV-treatment interruption data
    • Adams BM, Banks HT, Davidian M, Rosenberg ES (2007) Estimation and prediction with HIV-treatment interruption data. Bull Math Biol 69(2):563-584.
    • (2007) Bull Math Biol , vol.69 , Issue.2 , pp. 563-584
    • Adams, B.M.1    Banks, H.T.2    Davidian, M.3    Rosenberg, E.S.4
  • 35
    • 0033768519 scopus 로고    scopus 로고
    • Risks and benefits of structured antiretroviral drug therapy interruptions in HIV-1 infection
    • Bonhoeffer S, Rembiszewski M, Ortiz GM, Nixon DF (2000) Risks and benefits of structured antiretroviral drug therapy interruptions in HIV-1 infection. AIDS 14(15):2313-2322.
    • (2000) AIDS , vol.14 , Issue.15 , pp. 2313-2322
    • Bonhoeffer, S.1    Rembiszewski, M.2    Ortiz, G.M.3    Nixon, D.F.4
  • 36
    • 79952705605 scopus 로고    scopus 로고
    • Revisiting immune exhaustion during HIV infection
    • Khaitan A, Unutmaz D (2011) Revisiting immune exhaustion during HIV infection. Curr HIV/AIDS Rep 8(1):4-11.
    • (2011) Curr HIV/AIDS Rep , vol.8 , Issue.1 , pp. 4-11
    • Khaitan, A.1    Unutmaz, D.2
  • 37
    • 70350743827 scopus 로고    scopus 로고
    • PD-1 and CTLA-4 inhibitory cosignaling pathways in HIV infection and the potential for therapeutic intervention
    • Kaufmann DE, Walker BD (2009) PD-1 and CTLA-4 inhibitory cosignaling pathways in HIV infection and the potential for therapeutic intervention. J Immunol 182(10):5891-5897.
    • (2009) J Immunol , vol.182 , Issue.10 , pp. 5891-5897
    • Kaufmann, D.E.1    Walker, B.D.2
  • 38
    • 57749177930 scopus 로고    scopus 로고
    • Asymmetric division of activated latently infected cells may explain the decay kinetics of the HIV-1 latent reservoir and intermittent viral blips
    • Rong L, Perelson AS (2009) Asymmetric division of activated latently infected cells may explain the decay kinetics of the HIV-1 latent reservoir and intermittent viral blips. Math Biosci 217(1):77-87.
    • (2009) Math Biosci , vol.217 , Issue.1 , pp. 77-87
    • Rong, L.1    Perelson, A.S.2
  • 39
    • 79956111917 scopus 로고    scopus 로고
    • Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections
    • Johnson PLF, et al. (2011) Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections. J Virol 85(11):5565-5570.
    • (2011) J Virol , vol.85 , Issue.11 , pp. 5565-5570
    • Johnson, P.L.F.1
  • 40
    • 84862189831 scopus 로고    scopus 로고
    • Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection
    • Archin NM, et al. (2012) Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection. Proc Natl Acad Sci USA 109(24):9523-9528.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.24 , pp. 9523-9528
    • Archin, N.M.1
  • 41
    • 0034615789 scopus 로고    scopus 로고
    • Modeling plasma virus concentration during primary HIV infection
    • Stafford MA, et al. (2000) Modeling plasma virus concentration during primary HIV infection. J Theor Biol 203(3):285-301.
    • (2000) J Theor Biol , vol.203 , Issue.3 , pp. 285-301
    • Stafford, M.A.1
  • 42
    • 78649669772 scopus 로고    scopus 로고
    • Treatment-mediated alterations in HIV fitness preserve CD4+ T cell counts but have minimal effects on viral load
    • Vaidya NK, et al. (2010) Treatment-mediated alterations in HIV fitness preserve CD4+ T cell counts but have minimal effects on viral load. PLOS Comput Biol 6(11):e1001012.
    • (2010) PLOS Comput Biol , vol.6 , Issue.11 , pp. e1001012
    • Vaidya, N.K.1
  • 43
    • 84876093634 scopus 로고    scopus 로고
    • Quantifying T lymphocyte turnover
    • De Boer RJ, Perelson AS (2013) Quantifying T lymphocyte turnover. J Theor Biol 327:45-87.
    • (2013) J Theor Biol , vol.327 , pp. 45-87
    • De Boer, R.J.1    Perelson, A.S.2
  • 44
    • 84887335296 scopus 로고    scopus 로고
    • Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans
    • Westera L, et al. (2013) Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans. Blood 122(13):2205-2212.
    • (2013) Blood , vol.122 , Issue.13 , pp. 2205-2212
    • Westera, L.1
  • 45
    • 33745245733 scopus 로고    scopus 로고
    • Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells
    • Bailey JR, et al. (2006) Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells. J Virol 80(13):6441-6457.
    • (2006) J Virol , vol.80 , Issue.13 , pp. 6441-6457
    • Bailey, J.R.1
  • 46
    • 84878084179 scopus 로고    scopus 로고
    • Stochastic analysis of pre- and postexposure prophylaxis against HIV infection
    • Conway JM, Konrad BP, Coombs D (2013) Stochastic analysis of pre- and postexposure prophylaxis against HIV infection. SIAM J Appl Math 73(2):904-928.
    • (2013) SIAM J Appl Math , vol.73 , Issue.2 , pp. 904-928
    • Conway, J.M.1    Konrad, B.P.2    Coombs, D.3
  • 47
    • 79952477165 scopus 로고    scopus 로고
    • Stochastic theory of early viral infection: Continuous versus burst production of virions
    • Pearson JE, Krapivsky P, Perelson AS (2011) Stochastic theory of early viral infection: Continuous versus burst production of virions. PLOS Comput Biol 7(2):e1001058.
    • (2011) PLOS Comput Biol , vol.7 , Issue.2 , pp. e1001058
    • Pearson, J.E.1    Krapivsky, P.2    Perelson, A.S.3
  • 48
    • 0032556667 scopus 로고    scopus 로고
    • A stochastic model for early HIV-1 population dynamics
    • Tuckwell HC, Le Corfec E (1998) A stochastic model for early HIV-1 population dynamics. J Theor Biol 195(4):451-463.
    • (1998) J Theor Biol , vol.195 , Issue.4 , pp. 451-463
    • Tuckwell, H.C.1    Le Corfec, E.2
  • 49
    • 4444341172 scopus 로고    scopus 로고
    • Kinetics of virus-specific CD8+ T cells and the control of human immunodeficiency virus infection
    • Davenport MP, Ribeiro RM, Perelson AS (2004) Kinetics of virus-specific CD8+ T cells and the control of human immunodeficiency virus infection. J Virol 78(18):10096-10103.
    • (2004) J Virol , vol.78 , Issue.18 , pp. 10096-10103
    • Davenport, M.P.1    Ribeiro, R.M.2    Perelson, A.S.3
  • 50
    • 0037385686 scopus 로고    scopus 로고
    • A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo
    • Markowitz M, et al. (2003) A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo. J Virol 77(8):5037-5038.
    • (2003) J Virol , vol.77 , Issue.8 , pp. 5037-5038
    • Markowitz, M.1
  • 51
    • 84907240033 scopus 로고    scopus 로고
    • Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1
    • Hill AL, Rosenbloom DIS, Fu F, Nowak MA, Siliciano RF (2014) Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1. Proc Natl Acad Sci USA 111(37):13475-13480.
    • (2014) Proc Natl Acad Sci USA , vol.111 , Issue.37 , pp. 13475-13480
    • Hill, A.L.1    Rosenbloom, D.I.S.2    Fu, F.3    Nowak, M.A.4    Siliciano, R.F.5
  • 52
    • 84887028999 scopus 로고    scopus 로고
    • Absence of detectable HIV-1 viremia after treatment cessation in an infant
    • Persaud D, et al. (2013) Absence of detectable HIV-1 viremia after treatment cessation in an infant. N Engl J Med 369(19):1828-1835.
    • (2013) N Engl J Med , vol.369 , Issue.19 , pp. 1828-1835
    • Persaud, D.1
  • 53
    • 84908290606 scopus 로고    scopus 로고
    • "Mississippi baby " now has detectable HIV, researchers find
    • July 10, Available at
    • NIH News (July 10, 2014) "Mississippi baby " now has detectable HIV, researchers find. National Institutes of Health News . Available at www.niaid.nih.gov/news/newsreleases/2014/pages/mississippibabyhiv.aspx.
    • (2014) National Institutes of Health News
  • 54
    • 62249101428 scopus 로고    scopus 로고
    • Pharmaceutical approaches to eradication of persistent HIV infection
    • Bowman M-C, Archin NM, Margolis DM (2009) Pharmaceutical approaches to eradication of persistent HIV infection. Expert Rev Mol Med 11:e6.
    • (2009) Expert Rev Mol Med , vol.11 , pp. e6
    • Bowman, M.-C.1    Archin, N.M.2    Margolis, D.M.3
  • 55
    • 56749097184 scopus 로고    scopus 로고
    • Early antiretroviral therapy and mortality among HIV-infected infants
    • Violari A, et al.; CHER Study Team (2008) Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med 359(21):2233-2244.
    • (2008) N Engl J Med , vol.359 , Issue.21 , pp. 2233-2244
    • Violari, A.1
  • 56
    • 33750451933 scopus 로고    scopus 로고
    • Viral and latent reservoir persistence in HIV-1-infected patients on therapy
    • Kim H, Perelson AS (2006) Viral and latent reservoir persistence in HIV-1-infected patients on therapy. PLOS Comput Biol 2(10):e135.
    • (2006) PLOS Comput Biol , vol.2 , Issue.10 , pp. e135
    • Kim, H.1    Perelson, A.S.2
  • 57
    • 78549235738 scopus 로고    scopus 로고
    • Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: Implications for eradication
    • Chun TW, et al. (2010) Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: Implications for eradication. AIDS 24(18):2803-2808.
    • (2010) AIDS , vol.24 , Issue.18 , pp. 2803-2808
    • Chun, T.W.1
  • 59
    • 0036354175 scopus 로고    scopus 로고
    • The dual role of CD4 T helper cells in the infection dynamics of HIV and their importance for vaccination
    • Altes HK, Wodarz D, Jansen VAA (2002) The dual role of CD4 T helper cells in the infection dynamics of HIV and their importance for vaccination. J Theor Biol 214(4):633-646.
    • (2002) J Theor Biol , vol.214 , Issue.4 , pp. 633-646
    • Altes, H.K.1    Wodarz, D.2    Jansen, V.A.A.3
  • 60
    • 0037963626 scopus 로고    scopus 로고
    • The race between initial T-helper expansion and virus growth upon HIV infection influences polyclonality of the response and viral set-point
    • Korthals Altes H, Ribeiro RM, de Boer RJ (2003) The race between initial T-helper expansion and virus growth upon HIV infection influences polyclonality of the response and viral set-point. Proc Biol Sci 270(1522):1349-1358.
    • (2003) Proc Biol Sci , vol.270 , Issue.1522 , pp. 1349-1358
    • Korthals Altes, H.1    Ribeiro, R.M.2    De Boer, R.J.3
  • 61
    • 84907313948 scopus 로고    scopus 로고
    • HIV-1 rebound following allogeneic stem cell transplantation and treatment interruption
    • Henrich TJ, et al. (2014) HIV-1 rebound following allogeneic stem cell transplantation and treatment interruption. Top Antiviral Med 22(e-1):71-72.
    • (2014) Top Antiviral Med , vol.22 , Issue.E-1 , pp. 71-72
    • Henrich, T.J.1
  • 62
    • 84877278315 scopus 로고    scopus 로고
    • Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation
    • Henrich TJ, et al. (2013) Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation. J Infect Dis 207(11):1694-1702.
    • (2013) J Infect Dis , vol.207 , Issue.11 , pp. 1694-1702
    • Henrich, T.J.1
  • 63
    • 84879284427 scopus 로고    scopus 로고
    • Insights into B cells and HIV-specific B-cell responses in HIV-infected individuals
    • Moir S, Fauci AS (2013) Insights into B cells and HIV-specific B-cell responses in HIV-infected individuals. Immunol Rev 254(1):207-224.
    • (2013) Immunol Rev , vol.254 , Issue.1 , pp. 207-224
    • Moir, S.1    Fauci, A.S.2
  • 64
    • 84883187027 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies and the search for an HIV-1 vaccine: The end of the beginning
    • Kwong PD, Mascola JR, Nabel GJ (2013) Broadly neutralizing antibodies and the search for an HIV-1 vaccine: The end of the beginning. Nat Rev Immunol 13(9):693-701.
    • (2013) Nat Rev Immunol , vol.13 , Issue.9 , pp. 693-701
    • Kwong, P.D.1    Mascola, J.R.2    Nabel, G.J.3
  • 65
    • 57349127300 scopus 로고    scopus 로고
    • Initial B-cell responses to transmitted human immunodeficiency virus type 1: Virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia
    • Tomaras GD, et al. (2008) Initial B-cell responses to transmitted human immunodeficiency virus type 1: Virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia. J Virol 82(24):12449-12463.
    • (2008) J Virol , vol.82 , Issue.24 , pp. 12449-12463
    • Tomaras, G.D.1
  • 66
    • 84887445284 scopus 로고    scopus 로고
    • Dendritic cell based vaccines for HIV infection: The way ahead
    • García F, et al. (2013) Dendritic cell based vaccines for HIV infection: The way ahead. Hum Vaccin Immunother 9(11):2445-2452.
    • (2013) Hum Vaccin Immunother , vol.9 , Issue.11 , pp. 2445-2452
    • García, F.1
  • 67
    • 84879571436 scopus 로고    scopus 로고
    • Therapeutic and prophylactic DNA vaccines for HIV-1
    • Ramirez LA, Arango T, Boyer J (2013) Therapeutic and prophylactic DNA vaccines for HIV-1. Expert Opin Biol Ther 13(4):563-573.
    • (2013) Expert Opin Biol Ther , vol.13 , Issue.4 , pp. 563-573
    • Ramirez, L.A.1    Arango, T.2    Boyer, J.3
  • 68
    • 84864203255 scopus 로고    scopus 로고
    • Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
    • Archin NM, et al. (2012) Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature 487(7408):482-485.
    • (2012) Nature , vol.487 , Issue.7408 , pp. 482-485
    • Archin, N.M.1
  • 71
    • 79958136377 scopus 로고    scopus 로고
    • Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation
    • Xing S, et al. (2011) Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. J Virol 85(12):6060-6064.
    • (2011) J Virol , vol.85 , Issue.12 , pp. 6060-6064
    • Xing, S.1
  • 72
    • 84891827613 scopus 로고    scopus 로고
    • Emerging strategies to deplete the HIV reservoir
    • Archin NM, Margolis DM (2014) Emerging strategies to deplete the HIV reservoir. Curr Opin Infect Dis 27(1):29-35.
    • (2014) Curr Opin Infect Dis , vol.27 , Issue.1 , pp. 29-35
    • Archin, N.M.1    Margolis, D.M.2


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