Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells

Oncotarget

Volumn 6, Issue 18, 2015, Pages 16488-16506

  Sachweh, Marijke C C ^a   Stafford, William C ^a   Drummond, Catherine J ^a   McCarthy, Anna R ^a   Higgins, Maureen ^b   Campbell, Johanna ^b   Brodin, Bertha ^a   Arnér, Elias S J ^a   Laín, Sonia ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Auranofin; Malignant melanoma; p53; Thioredoxin reductase 1; Vemurafenib

Indexed keywords

AURANOFIN; NUTLIN 3; OXIDOREDUCTASE INHIBITOR; PROTEIN P53; UNCLASSIFIED DRUG; [2 [[2 (1,3 BENZOTHIAZOL 2 YLSULFONYL)ETHYL]THIO] 1,3 BENZOXAZOLE]; ANTINEOPLASTIC AGENT; BENZOTHIAZOLE DERIVATIVE; BENZOXAZOLE DERIVATIVE; GLUTATHIONE; GLUTATHIONE REDUCTASE; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; MJ25 COMPOUND; PIPERAZINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SULFONAMIDE; SULFONE; THIOREDOXIN REDUCTASE 1; TP53 PROTEIN, HUMAN; TXNRD1 PROTEIN, HUMAN; VEMURAFENIB;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA; MELANOMA; MOUSE; NONHUMAN; OXIDATIVE STRESS; REDOX STRESS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; DRUG EFFECTS; GENETICS; HCT 116 CELL LINE; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; AURANOFIN; BENZOTHIAZOLES; BENZOXAZOLES; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME ACTIVATION; GLUTATHIONE; GLUTATHIONE REDUCTASE; HCT116 CELLS; HUMANS; IMIDAZOLES; INDOLES; MELANOMA; MICE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PIPERAZINES; REACTIVE OXYGEN SPECIES; SULFONAMIDES; SULFONES; THIOREDOXIN REDUCTASE 1; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84937843579     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4108     Document Type: Article

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