Hypomorphism of Fto and Rpgrip1l causes obesity in mice

Journal of Clinical Investigation

Volumn 126, Issue 5, 2016, Pages 1897-1910

  Stratigopoulos, George ^a   Burnett, Lisa Cole ^a   Rausch, Richard ^a   Gill, Richard ^a   Penn, David Barth ^b   Skowronski, Alicja A ^a   LeDuc, Charles A ^a   Lanzano, Anthony J ^c   Zhang, Pumin ^d   Storm, Daniel R ^e   Egli, Dieter ^a   Leibel, Rudolph L ^a  

^a Columbia University ^*  (United States)

^b Alaska Family Medicine Residency   (United States)

^c John F Kennedy High School   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CUX1; UNCLASSIFIED DRUG; ALPHA KETOGLUTARATE DEPENDENT DIOXYGENASE FTO; FTO PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; IRX3 PROTEIN, MOUSE; IRX5 PROTEIN, MOUSE; PROTEIN; PROTEIN P130; RBL2 PROTEIN, MOUSE; RPGRIP1 PROTEIN, MOUSE;

AKTIP GENE; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BODY COMPOSITION; CALORIC INTAKE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENERGY EXPENDITURE; ENERGY HOMEOSTASIS; FTO GENE; GENE; GENE EXPRESSION; GENETIC VARIATION; HETEROZYGOSITY; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VIVO STUDY; INDUCED PLURIPOTENT STEM CELL; IRX3 GENE; IRX5 GENE; MALE; MOUSE; NERVE CELL; NONHUMAN; OBESITY; PRIORITY JOURNAL; RBL2 GENE; RPGRIP1L GENE; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; BIOSYNTHESIS; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GENETICS; HYPOTHALAMUS; INTRON; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

ALLELES; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO; ANIMALS; ENERGY METABOLISM; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; HYPOTHALAMUS; INTRONS; MICE; MICE, TRANSGENIC; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; RETINOBLASTOMA-LIKE PROTEIN P130; TRANSCRIPTION FACTORS;

EID: 84988473723     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI85526     Document Type: Article

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