The demethylase activity of FTO (Fat mass and obesity associated protein) is required for preadipocyte differentiation

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Zhang, Meizi ^a   Zhang, Ying ^a   Ma, Jun ^a   Guo, Feima ^a   Cao, Qian ^a   Zhang, Yu ^a   Zhou, Bin ^b   Chai, Jijie ^b   Zhao, Wenqing ^a   Zhao, Renbin ^a  

^a CHINA ACADEMY OF SPACE TECHNOLOGY   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

6 N METHYLADENOSINE; FAT MASS AND OBESITY ASSOCIATED PROTEIN; OXYGENASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ADENOSINE; ALPHA KETOGLUTARATE DEPENDENT DIOXYGENASE FTO; ANTIDIABETIC AGENT; BIOLOGICAL MARKER; DNA METHYLTRANSFERASE; FTO PROTEIN, MOUSE; N(6)-METHYLADENOSINE; PROTEIN;

ADIPOGENESIS; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DEMETHYLATION; GENE OVEREXPRESSION; MISSENSE MUTATION; NONHUMAN; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; 3T3 CELL LINE; ADIPOCYTE; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DNA METHYLATION; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MOUSE; OBESITY; PHYSIOLOGY;

3T3-L1 CELLS; ADENOSINE; ADIPOCYTES; ADIPOGENESIS; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO; ANIMALS; BIOMARKERS; CELL DIFFERENTIATION; DNA METHYLATION; DNA MODIFICATION METHYLASES; GENE EXPRESSION PROFILING; HYPOGLYCEMIC AGENTS; MICE; OBESITY; PPAR GAMMA; PROTEINS; RNA, SMALL INTERFERING; THIAZOLIDINEDIONES;

EID: 84941763224     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0133788     Document Type: Article

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