Restricted expression of somatostatin receptor 3 to primary cilia in the pancreatic islets and adenohypophysis of mice

Biomedical Research

Volumn 32, Issue 1, 2011, Pages 73-81

  Iwanaga, Toshihiko ^a   Miki, Takashi ^b   Takahashi Iwanaga, Hiromi ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOSTATIN RECEPTOR 3;

ADENOHYPOPHYSIS; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; ENDOCRINE CELL; EUKARYOTIC FLAGELLUM; GROWTH HORMONE SECRETING CELL; HYPOPHYSIS CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MICROVILLUS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SCANNING ELECTRON MICROSCOPY;

ADENYLATE CYCLASE; ANIMALS; CELL LINE; CILIA; CRICETINAE; GLUCAGON; GROWTH HORMONE; GUINEA PIGS; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED BALB C; PITUITARY GLAND, ANTERIOR; RATS; RECEPTORS, SOMATOSTATIN;

MUS;

EID: 79952806066     PISSN: 03886107     EISSN: 1880313X     Source Type: Journal    
DOI: 10.2220/biomedres.32.73     Document Type: Article

References (40)

1. Aughsteen AA (2001) The ultrastructure of primary cilia in the endocrine and excretory duct cells of pancreas of mice and rats. Eur J Morphol 39, 277-283.
2. Barnes BG (1961) Ciliated secretory cells in the pars distalis of the mouse hypophysis. J Ultrast Res 5, 453-467.
3. Berbari NF, Lewis JS, Bishop GA, Askwith CC and Mykytyn K (2008) Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia. Proc Natl Acad Sci USA 105, 4242-4246.
4. Bishop GA, Berbari NF, Lewis JS and Mykytyn K (2007) Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain. J Comp Neurol 505, 562-571.
5. Cano DA, Sekine S and Hebrok M (2006) Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis. Gastroenterology 131, 1856-1869.
6. Csaba Z and Dournaud P (2001) Cellular biology of soma-tostatin receptors. Neuropeptides 35:1-23
7. Fujita T, Kobayashi S and Serizawa Y (1981) Intercellular canalicule system in pancreatic islet. Biomed Res 2 (Suppl), 115-118.
8. Gosney JR (1992) Pulmonary Endocrine Pathology. Endocrine cells and endocrine tumours of the lung. Butterworth-Hinemann Ltd, Oxford, London
9. Granot Z, Swisa A, Magenheim J, Stolovich-Rain M, Fujimoto W, Manduchi E, Miki T, Lennerz JK, Stoeckert CJ Jr, Meyuhas O, Seino S, Permutt MA, Piwnica-Worms H, Bardeesy N and Dor Y (2009) LKB1 regulates pancreatic β cell size, polarity, and function. Cell Metab 19, 296-308.
10. Hamon M, Doucet E, Lefèvre K, Miquel M-C, Lanfumey L, Insausti R, Frechilla D, Del Rio J and Vergé D (1999) Antibodies and antisense oligonucleotide for probing the distribution and putative functions of central 5-HT6 receptors. Neuropsychopharmacology 21, 68S-76S.
11. Händel M, Schultz S, Stanarius A, Schreff M, Erdtmann-Vourliotis M, Schmidt H, Wolf G and Hollt V (1999) Selective targeting of somatostatin receptor 3 to neuronal cilia. Neuroscience 89, 909-926.
12. Iwanaga T, Ito S, Yamada Y and Fujita T (1983) Cytochemical demonstration of somatostatin 28-(1-14)-like immunore-activity in the rat hypothalamus and gastro-enteropancreatic endocrine system. Endocrinology 113, 1839-1844.
13. Kameda Y, Oyama H, Endoh M and Horino M (1982) Soma-tostatin immunoreactive C cells in thyroid glands from various mammalian species. Anat Rec 204, 161-170.
14. Kimura N, Schindler M, Kasai N and Kimura I (2001) Immunohistochemical localization of somatostatin receptor type 2A in rat and human tissues. Endocr J 48, 95-102.
15. Kondo H (1985) Immunohistochemical analysis of the localization of neuropeptides in the adrenal gland. Arch Histol Jpn 48, 453-481.
16. Kumar U, Sasi R, Suresh S, Patel A, Thangaraju M, Metrakos P, Patel SC and Patel YC (1999) Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells. Diabetes 48, 77-85.
17. Kumar U (2007) Colocalization of somatostatin receptor subtypes (SSTR1-5) with somatostatin, NADPH-diaphorase (NADPH-d), and tyrosine hydroxylase in the rat hypothala-mus. J Comp Neurol 504, 185-205.
18. Ludvigsen E, Olsson R, Stridsberg M, Janson ET and Sandler S (2004) Expression and distribution of somatostatin receptor subtypes in the pancreatic islets of mice and rats. J Histo-chem Cytochem 52, 391-400.
19. Mezey É, Hunyady B, Mitra S, Hayes E, Liu Q, Schaeffer J and Schonbrunn A (1998) Cell specific expression of the SS-T2A and SST5 somatostatin receptors in the rat anterior pituitary. Endocrinology 139, 414-419.
20. Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peränen J, Merdes A, Slusarski DC, Scheller RH, Bazan JF, Sheffeld VC and Jackson PK (2007) A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell 129, 1201-1213.
21. Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AEH, Lu W, Brown EM, Quinn SJ, Ingber DE and Zhou J (2003) Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet 33, 129-137.
22. Nielsen S, Møllgård K, Clement CA, Veland IR, Awan A, Yoder BK, Novak I and Christensen ST (2008) Characterization of primary cilia and hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines. Dev Dyn 237, 2039-2052.
23. Olias G, Viollet C, Kusserow H, Epelbaum J and Meyerhof W (2004) Regulation and function of somatostatin receptors. J Neurochem 89, 1057-1091.
24. Pissios P, Bradley RL and Maratos-Flier E (2006) Expanding the scales: The multiple roles of MCH in regulating energy balance and other biological functions. Endocr Rev 27, 606- 620.
25. Portela-Gomes GM, Grimelius L, Westermark P and Strids-berg M (2010) Somatostatin receptor subtypes in human type 2 diabetic islets. Pancreas 39, 836-842.
26. Praetorius HA and Spring KR (2001) Bending the MDCK cell primary cilium increases intracellular calcium. J Membr Biol 184, 71-79.
27. Praetorius HA and Spring KR (2003) The renal cell primary cilium functions as a flow sensor. Curr Opin Nephrol Hyper-tens 12, 517-520.
28. Reichlin S (1983) Somatostatin. N Engl J Med 309, 1495- 1501
29. di Sant'Agnese PA and de Mesy Jensen KL (1984) Soma-tostatin and/or somatostatin-like immunoreactive endocrine-paracrine cells in the human prostate gland. Arch Pathol Lab Med 108, 693-696.
30. Singh V, Brendel MD, Zacharias S, Mergler S, Jahr H, Wie-denmann B, Bretzel RG, Plöckinger U and Strowski MZ (2007) Characterization of somatostatin receptor subtype-specific regulation of insulin and glucagons secretion: An in vitro study on isolated human pancreatic islets. J Clin Endo-crinol Metab 92, 673-680.
31. Stanic D, Malmgren H, He H, Scott L, Aperia A and Hökfelt T (2009) Developmental changes in frequency of the ciliary somatostatin receptor 3 protein. Brain Res 1249, 101-112.
32. Strowski MZ, Kohler M, Chen HY, Trumbauer ME, Li Z, Szalkowski D, Gopal-Truter S, Fisher JK, Schaeffer JM, Blake AD, Zhang BB and Wilkinson HA (2003) Somatosta-tin receptor subtype 5 regulates insulin secretion and glucose homeostasis. Mol Endocrinol 17, 93-106.
33. Strowski MZ and Blake AD (2008) Function and expression of somatostatin receptors of the endocrine pancreas. Mol Cell Endocrinol 286, 169-179.
34. Takahashi-Iwanaga H and Fujita T (1986) Application of an NaOH maceration method to a scanning electron microscopic observation of Ito cells in the rat liver. Arch Histol Jpn 49, 349-357.
35. Tobin JL and Beales PL (2007) Bardet-Biedl syndrome: Beyond the cilium. Pediatr Nephrol 22, 926-936.
36. Wang XP, Norman MA, Yang J, Cheung A, Moldovan S, DeMayo FJ and Brunicardi FC (2004) Double-gene ablation of SSTR1 and SSTR5 results in hyper-insulinemia and improved glucose tolerance in mice. Surgery 136, 585-592.
37. Wheatley DN (1967) Cilia and centrioles of the rat adrenal cortex. J Anat 101, 223-237.
38. Wheatley DN, Wang AM and Strugnell GE (1996) Expression of primary cilia in mammalian cells. Cell Biol Int 20, 73-81.
39. Yamamoto M and Kataoka K (1986) Electron microscopic observation of the primary cilium in the pancreatic islets. Arch Histol Jpn 49, 449-457.
40. Yang S-K and Chen C (2007) Involvement of somatostatin receptor subtypes in membrane ion channel modifcation by somatostatin in pituitary somatotropes. Clin Exp Pharmacol Physiol 34, 1221-1227.