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Volumn 19, Issue 5, 2014, Pages 767-779

Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the fto locus, causes increased adiposity in mice

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN RECEPTOR; FTM PROTEIN, MOUSE; FTO (FAT MASS AND OBESITY ASSOCIATED) PROTEIN, MOUSE; LEPTIN; PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; STAT3 PROTEIN;

EID: 84899900892     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.04.009     Document Type: Article
Times cited : (132)

References (56)
  • 3
    • 41949116864 scopus 로고    scopus 로고
    • Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
    • N.F. Berbari, J.S. Lewis, G.A. Bishop, C.C. Askwith, and K. Mykytyn Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia Proc. Natl. Acad. Sci. USA 105 2008 4242 4246
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 4242-4246
    • Berbari, N.F.1    Lewis, J.S.2    Bishop, G.A.3    Askwith, C.C.4    Mykytyn, K.5
  • 5
    • 38049092146 scopus 로고    scopus 로고
    • Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain
    • G.A. Bishop, N.F. Berbari, J. Lewis, and K. Mykytyn Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain J. Comp. Neurol. 505 2007 562 571
    • (2007) J. Comp. Neurol. , vol.505 , pp. 562-571
    • Bishop, G.A.1    Berbari, N.F.2    Lewis, J.3    Mykytyn, K.4
  • 6
    • 1842536210 scopus 로고    scopus 로고
    • Trophic action of leptin on hypothalamic neurons that regulate feeding
    • S.G. Bouret, S.J. Draper, and R.B. Simerly Trophic action of leptin on hypothalamic neurons that regulate feeding Science 304 2004 108 110
    • (2004) Science , vol.304 , pp. 108-110
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 7
    • 84863051235 scopus 로고    scopus 로고
    • Distinct roles for specific leptin receptor signals in the development of hypothalamic feeding circuits
    • S.G. Bouret, S.H. Bates, S. Chen, M.G. Myers Jr., and R.B. Simerly Distinct roles for specific leptin receptor signals in the development of hypothalamic feeding circuits J. Neurosci. 32 2012 1244 1252
    • (2012) J. Neurosci. , vol.32 , pp. 1244-1252
    • Bouret, S.G.1    Bates, S.H.2    Chen, S.3    Myers, Jr.M.G.4    Simerly, R.B.5
  • 8
    • 70349728485 scopus 로고    scopus 로고
    • Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types
    • C. Cadieux, V. Kedinger, L. Yao, C. Vadnais, M. Drossos, M. Paquet, and A. Nepveu Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types Cancer Res. 69 2009 7188 7197
    • (2009) Cancer Res. , vol.69 , pp. 7188-7197
    • Cadieux, C.1    Kedinger, V.2    Yao, L.3    Vadnais, C.4    Drossos, M.5    Paquet, M.6    Nepveu, A.7
  • 9
    • 57749121512 scopus 로고    scopus 로고
    • An obesity-associated FTO gene variant and increased energy intake in children
    • J.E. Cecil, R. Tavendale, P. Watt, M.M. Hetherington, and C.N. Palmer An obesity-associated FTO gene variant and increased energy intake in children N. Engl. J. Med. 359 2008 2558 2566
    • (2008) N. Engl. J. Med. , vol.359 , pp. 2558-2566
    • Cecil, J.E.1    Tavendale, R.2    Watt, P.3    Hetherington, M.M.4    Palmer, C.N.5
  • 14
    • 70350647201 scopus 로고    scopus 로고
    • Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO
    • M. den Hoed, M.S. Westerterp-Plantenga, F.G. Bouwman, E.C. Mariman, and K.R. Westerterp Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO Am. J. Clin. Nutr. 90 2009 1426 1432
    • (2009) Am. J. Clin. Nutr. , vol.90 , pp. 1426-1432
    • Den Hoed, M.1    Westerterp-Plantenga, M.S.2    Bouwman, F.G.3    Mariman, E.C.4    Westerterp, K.R.5
  • 17
    • 33748327050 scopus 로고    scopus 로고
    • The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly
    • J.A. Follit, R.A. Tuft, K.E. Fogarty, and G.J. Pazour The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly Mol. Biol. Cell 17 2006 3781 3792
    • (2006) Mol. Biol. Cell , vol.17 , pp. 3781-3792
    • Follit, J.A.1    Tuft, R.A.2    Fogarty, K.E.3    Pazour, G.J.4
  • 19
    • 79952154035 scopus 로고    scopus 로고
    • Induction of leptin resistance by activation of cAMP-Epac signaling
    • M. Fukuda, K.W. Williams, L. Gautron, and J.K. Elmquist Induction of leptin resistance by activation of cAMP-Epac signaling Cell Metab. 13 2011 331 339
    • (2011) Cell Metab. , vol.13 , pp. 331-339
    • Fukuda, M.1    Williams, K.W.2    Gautron, L.3    Elmquist, J.K.4
  • 21
    • 79958806992 scopus 로고    scopus 로고
    • Reproducibility and accuracy of body composition assessments in mice by dual energy x-ray absorptiometry and time domain nuclear magnetic resonance
    • S. Halldorsdottir, J. Carmody, C.N. Boozer, C.A. Leduc, and R.L. Leibel Reproducibility and accuracy of body composition assessments in mice by dual energy x-ray absorptiometry and time domain nuclear magnetic resonance Int. J. Body Compos. Res. 7 2009 147 154
    • (2009) Int. J. Body Compos. Res. , vol.7 , pp. 147-154
    • Halldorsdottir, S.1    Carmody, J.2    Boozer, C.N.3    Leduc, C.A.4    Leibel, R.L.5
  • 22
    • 79953227708 scopus 로고    scopus 로고
    • A loop matters for FTO substrate selection
    • Z. Han, N. Huang, T. Niu, and J. Chai A loop matters for FTO substrate selection Protein Cell 1 2010 616 620
    • (2010) Protein Cell , vol.1 , pp. 616-620
    • Han, Z.1    Huang, N.2    Niu, T.3    Chai, J.4
  • 29
    • 79955368025 scopus 로고    scopus 로고
    • Rabs and other small GTPases in ciliary transport
    • Y.S. Lim, C.E. Chua, and B.L. Tang Rabs and other small GTPases in ciliary transport Biol. Cell 103 2011 209 221
    • (2011) Biol. Cell , vol.103 , pp. 209-221
    • Lim, Y.S.1    Chua, C.E.2    Tang, B.L.3
  • 30
    • 79960036570 scopus 로고    scopus 로고
    • Caenorhabditis elegans ciliary protein NPHP-8, the homologue of human RPGRIP1L, is required for ciliogenesis and chemosensation
    • L. Liu, M. Zhang, Z. Xia, P. Xu, L. Chen, and T. Xu Caenorhabditis elegans ciliary protein NPHP-8, the homologue of human RPGRIP1L, is required for ciliogenesis and chemosensation Biochem. Biophys. Res. Commun. 410 2011 626 631
    • (2011) Biochem. Biophys. Res. Commun. , vol.410 , pp. 626-631
    • Liu, L.1    Zhang, M.2    Xia, Z.3    Xu, P.4    Chen, L.5    Xu, T.6
  • 31
    • 77954362705 scopus 로고    scopus 로고
    • Direct interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46
    • B.F. Lucker, M.S. Miller, S.A. Dziedzic, P.T. Blackmarr, and D.G. Cole Direct interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46 J. Biol. Chem. 285 2010 21508 21518
    • (2010) J. Biol. Chem. , vol.285 , pp. 21508-21518
    • Lucker, B.F.1    Miller, M.S.2    Dziedzic, S.A.3    Blackmarr, P.T.4    Cole, D.G.5
  • 34
    • 84899947362 scopus 로고    scopus 로고
    • Cilia, tubby mice, and obesity
    • S. Mukhopadhyay, and P.K. Jackson Cilia, tubby mice, and obesity Cilia 2 2013 1
    • (2013) Cilia , vol.2 , pp. 1
    • Mukhopadhyay, S.1    Jackson, P.K.2
  • 36
    • 33744959239 scopus 로고    scopus 로고
    • Mapping of binding site III in the leptin receptor and modeling of a hexameric leptin.leptin receptor complex
    • F. Peelman, H. Iserentant, A.S. De Smet, J. Vandekerckhove, L. Zabeau, and J. Tavernier Mapping of binding site III in the leptin receptor and modeling of a hexameric leptin.leptin receptor complex J. Biol. Chem. 281 2006 15496 15504
    • (2006) J. Biol. Chem. , vol.281 , pp. 15496-15504
    • Peelman, F.1    Iserentant, H.2    De Smet, A.S.3    Vandekerckhove, J.4    Zabeau, L.5    Tavernier, J.6
  • 41
    • 48749132799 scopus 로고    scopus 로고
    • Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure
    • J.R. Speakman, K.A. Rance, and A.M. Johnstone Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure Obesity (Silver Spring) 16 2008 1961 1965
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 1961-1965
    • Speakman, J.R.1    Rance, K.A.2    Johnstone, A.M.3
  • 43
    • 78649464259 scopus 로고    scopus 로고
    • Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling
    • G. Stratigopoulos, C.A. LeDuc, M.L. Cremona, W.K. Chung, and R.L. Leibel Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling J. Biol. Chem. 286 2011 2155 2170
    • (2011) J. Biol. Chem. , vol.286 , pp. 2155-2170
    • Stratigopoulos, G.1    Leduc, C.A.2    Cremona, M.L.3    Chung, W.K.4    Leibel, R.L.5
  • 45
    • 77649303960 scopus 로고    scopus 로고
    • Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats
    • Y.C. Tung, E. Ayuso, X. Shan, F. Bosch, S. O'Rahilly, A.P. Coll, and G.S. Yeo Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats PLoS ONE 5 2010 e8771
    • (2010) PLoS ONE , vol.5 , pp. 8771
    • Tung, Y.C.1    Ayuso, E.2    Shan, X.3    Bosch, F.4    O'Rahilly, S.5    Coll, A.P.6    Yeo, G.S.7
  • 47
    • 34547800833 scopus 로고    scopus 로고
    • Ftm is a novel basal body protein of cilia involved in Shh signalling
    • J. Vierkotten, R. Dildrop, T. Peters, B. Wang, and U. Rüther Ftm is a novel basal body protein of cilia involved in Shh signalling Development 134 2007 2569 2577
    • (2007) Development , vol.134 , pp. 2569-2577
    • Vierkotten, J.1    Dildrop, R.2    Peters, T.3    Wang, B.4    Rüther, U.5
  • 49
    • 79957945033 scopus 로고    scopus 로고
    • Involvement of Leptin Receptor (LepRb)-STAT3 Signaling Pathway in Brain FTO Downregulation during Energy Restriction
    • P. Wang, F.J. Yang, H. Du, Y.F. Guan, T.Y. Xu, X.W. Xu, D.F. Su, and C.Y. Miao Involvement of Leptin Receptor (LepRb)-STAT3 Signaling Pathway in Brain FTO Downregulation during Energy Restriction Mol. Med. 17 2011 523 532
    • (2011) Mol. Med. , vol.17 , pp. 523-532
    • Wang, P.1    Yang, F.J.2    Du, H.3    Guan, Y.F.4    Xu, T.Y.5    Xu, X.W.6    Su, D.F.7    Miao, C.Y.8
  • 52
    • 79955513961 scopus 로고    scopus 로고
    • MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis
    • C.L. Williams, C. Li, K. Kida, P.N. Inglis, S. Mohan, L. Semenec, N.J. Bialas, R.M. Stupay, N. Chen, and O.E. Blacque et al. MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis J. Cell Biol. 192 2011 1023 1041
    • (2011) J. Cell Biol. , vol.192 , pp. 1023-1041
    • Williams, C.L.1    Li, C.2    Kida, K.3    Inglis, P.N.4    Mohan, S.5    Semenec, L.6    Bialas, N.J.7    Stupay, R.M.8    Chen, N.9    Blacque, O.E.10
  • 53
    • 0347286631 scopus 로고    scopus 로고
    • Functional analysis of leptin receptor activation using a Janus kinase/signal transducer and activator of transcription complementation assay
    • L. Zabeau, D. Defeau, J. Van der Heyden, H. Iserentant, J. Vandekerckhove, and J. Tavernier Functional analysis of leptin receptor activation using a Janus kinase/signal transducer and activator of transcription complementation assay Mol. Endocrinol. 18 2004 150 161
    • (2004) Mol. Endocrinol. , vol.18 , pp. 150-161
    • Zabeau, L.1    Defeau, D.2    Van Der Heyden, J.3    Iserentant, H.4    Vandekerckhove, J.5    Tavernier, J.6
  • 54
    • 65649147891 scopus 로고    scopus 로고
    • Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy
    • N.A. Zaghloul, and N. Katsanis Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy J. Clin. Invest. 119 2009 428 437
    • (2009) J. Clin. Invest. , vol.119 , pp. 428-437
    • Zaghloul, N.A.1    Katsanis, N.2
  • 55
    • 0036321620 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding
    • A.Z. Zhao, J.N. Huan, S. Gupta, R. Pal, and A. Sahu A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding Nat. Neurosci. 5 2002 727 728
    • (2002) Nat. Neurosci. , vol.5 , pp. 727-728
    • Zhao, A.Z.1    Huan, J.N.2    Gupta, S.3    Pal, R.4    Sahu, A.5
  • 56
    • 0037389431 scopus 로고    scopus 로고
    • The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: Subserving RPGR function and participating in disk morphogenesis
    • Y. Zhao, D.H. Hong, B. Pawlyk, G. Yue, M. Adamian, M. Grynberg, A. Godzik, and T. Li The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis Proc. Natl. Acad. Sci. USA 100 2003 3965 3970
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 3965-3970
    • Zhao, Y.1    Hong, D.H.2    Pawlyk, B.3    Yue, G.4    Adamian, M.5    Grynberg, M.6    Godzik, A.7    Li, T.8


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