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Volumn 24, Issue 4, 2004, Pages 1493-1504

Regulation of Apoptosis by the Ft1 Protein, a New Modulator of Protein Kinase B/Akt

Author keywords

[No Author keywords available]

Indexed keywords

3 PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE; 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE; DEXAMETHASONE; DNA BINDING PROTEIN; FAS LIGAND; FASL PROTEIN; FUSED TOES PROTEIN; GLUCOCORTICOID; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN; ONCOPROTEIN; PROTEIN; PROTEIN FT1; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PROTO ONCOGENE PROTEIN AKT; PROTO-ONCOGENE PROTEIN AKT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NF AT; TRANSCRIPTION FACTOR NF-AT; UNCLASSIFIED DRUG;

EID: 0842304224     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.4.1493-1504.2004     Document Type: Article
Times cited : (102)

References (52)
  • 3
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
    • Alessi, D. R., S. R. James, C. P. Downes, A. B. Holmes, P. R. Gaffney, C. B. Reese, and P. Cohen. 1997. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα. Curr. Biol. 7:261-269.
    • (1997) Curr. Biol. , vol.7 , pp. 261-269
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.5    Reese, C.B.6    Cohen, P.7
  • 4
    • 0030890234 scopus 로고    scopus 로고
    • Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3
    • Beals, C. R., C. M. Sheridan, C. W. Turck, P. Gardner, and G. R. Crabtree. 1997. Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science 275:1930-1934.
    • (1997) Science , vol.275 , pp. 1930-1934
    • Beals, C.R.1    Sheridan, C.M.2    Turck, C.W.3    Gardner, P.4    Crabtree, G.R.5
  • 5
    • 0033545393 scopus 로고    scopus 로고
    • Intracellular signalling: PDK1 - A kinase at the hub of things
    • Belham, C., S. Wu, and J. Avruch. 1999. Intracellular signalling: PDK1 - a kinase at the hub of things. Curr. Biol. 9:R93-R96.
    • (1999) Curr. Biol. , vol.9
    • Belham, C.1    Wu, S.2    Avruch, J.3
  • 6
    • 0035499454 scopus 로고    scopus 로고
    • Ten years of protein kinase B signalling: A hard Akt to follow
    • Brazil, D. P., and B. A. Hemmings. 2001. Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem. Sci. 26:657-664.
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 657-664
    • Brazil, D.P.1    Hemmings, B.A.2
  • 7
    • 0036849331 scopus 로고    scopus 로고
    • PKB binding proteins. Getting in on the Akt
    • Brazil, D. P., J. Park, and B. A. Hemmings. 2002. PKB binding proteins. Getting in on the Akt. Cell 111:293-303.
    • (2002) Cell , vol.111 , pp. 293-303
    • Brazil, D.P.1    Park, J.2    Hemmings, B.A.3
  • 8
    • 0032546972 scopus 로고    scopus 로고
    • Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway
    • Chen, C. Y., F. Del Gatto-Konczak, Z. Wu, and M. Karin. 1998. Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway. Science 280:1945-1949.
    • (1998) Science , vol.280 , pp. 1945-1949
    • Chen, C.Y.1    Del Gatto-Konczak, F.2    Wu, Z.3    Karin, M.4
  • 9
    • 0033525748 scopus 로고    scopus 로고
    • 2+, calcineurin, and NF-AT
    • 2+, calcineurin, and NF-AT. Cell 96:611-614.
    • (1999) Cell , vol.96 , pp. 611-614
    • Crabtree, G.R.1
  • 10
    • 0036234543 scopus 로고    scopus 로고
    • NFAT signaling: Choreographing the social lives of cells
    • Crabtree, G. R., and E. N. Olson. 2002. NFAT signaling: choreographing the social lives of cells. Cell 109:S67-S79.
    • (2002) Cell , vol.109
    • Crabtree, G.R.1    Olson, E.N.2
  • 11
    • 0033537849 scopus 로고    scopus 로고
    • Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling
    • Craddock, B. L., E. A. Orchiston, H. J. Hinton, and M. J. Welham. 1999. Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling. J. Biol. Chem. 274:10633-10640.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10633-10640
    • Craddock, B.L.1    Orchiston, E.A.2    Hinton, H.J.3    Welham, M.J.4
  • 12
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross, D. A., D. R. Alessi, P. Cohen, M. Andjelkovich, and B. A. Hemmings. 1995. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378:785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 13
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta, S. R., A. Brunet, and M. E. Greenberg. 1999. Cellular survival: a play in three Akts. Genes Dev. 13:2905-2927.
    • (1999) Genes Dev. , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 14
    • 0029907572 scopus 로고    scopus 로고
    • Glucocorticoids modulate CD28 mediated pathways for interleukin 2 production in human T cells: Evidence for posttranscriptional regulation
    • Fessler, B. J., F. Paliogianni, N. Hama, J. E. Balow, and D. T. Boumpas. 1996. Glucocorticoids modulate CD28 mediated pathways for interleukin 2 production in human T cells: evidence for posttranscriptional regulation. Transplantation 62:1113-1118.
    • (1996) Transplantation , vol.62 , pp. 1113-1118
    • Fessler, B.J.1    Paliogianni, F.2    Hama, N.3    Balow, J.E.4    Boumpas, D.T.5
  • 15
    • 0025084605 scopus 로고
    • Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor
    • Fiering, S., J. P. Northrop, G. P. Nolan, P. S. Mattila, G. R. Crabtree, and L. A. Herzenberg. 1990. Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. Genes Dev. 4:1823-1834.
    • (1990) Genes Dev. , vol.4 , pp. 1823-1834
    • Fiering, S.1    Northrop, J.P.2    Nolan, G.P.3    Mattila, P.S.4    Crabtree, G.R.5    Herzenberg, L.A.6
  • 16
    • 0033912699 scopus 로고    scopus 로고
    • The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase
    • Genot, E. M., C. Arrieumerlou, G. Ku, B. M. Burgering, A. Weiss, and I. M. Kramer. 2000. The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase. Mol. Cell. Biol. 20:5469-5478.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5469-5478
    • Genot, E.M.1    Arrieumerlou, C.2    Ku, G.3    Burgering, B.M.4    Weiss, A.5    Kramer, I.M.6
  • 17
    • 0034647238 scopus 로고    scopus 로고
    • Antiparallel leucine zipper-directed protein reassembly: Application to the green fluorescent protein
    • Ghosh, I., A. D. Hamilton, and L. Regan. 2000. Antiparallel leucine zipper-directed protein reassembly: application to the green fluorescent protein. J. Am. Chem. Soc. 2000:5658-5659.
    • (2000) J. Am. Chem. Soc. , vol.2000 , pp. 5658-5659
    • Ghosh, I.1    Hamilton, A.D.2    Regan, L.3
  • 18
    • 0037111418 scopus 로고    scopus 로고
    • A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance
    • Goleva, E., K. O. Kisich, and D. Y. Leung. 2002. A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance. J. Immunol. 169:5934-5940.
    • (2002) J. Immunol. , vol.169 , pp. 5934-5940
    • Goleva, E.1    Kisich, K.O.2    Leung, D.Y.3
  • 19
    • 0028837242 scopus 로고
    • Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor
    • Helmberg, A., N. Auphan, C. Caelles, and M. Karin. 1995. Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor. EMBO J. 14:452-460.
    • (1995) EMBO J. , vol.14 , pp. 452-460
    • Helmberg, A.1    Auphan, N.2    Caelles, C.3    Karin, M.4
  • 20
    • 0033564734 scopus 로고    scopus 로고
    • Cytokine-induced protein kinase B activation and Bad phosphorylation do not correlate with cell survival of hemopoietic cells
    • Hinton, H. J., and M. J. Welham. 1999. Cytokine-induced protein kinase B activation and Bad phosphorylation do not correlate with cell survival of hemopoietic cells. J. Immunol. 162:7002-7009.
    • (1999) J. Immunol. , vol.162 , pp. 7002-7009
    • Hinton, H.J.1    Welham, M.J.2
  • 22
    • 0036241055 scopus 로고    scopus 로고
    • Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation
    • Hu, C. D., Y. Chinenov, and T. K. Kerppola. 2002. Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol. Cell 9:789-798.
    • (2002) Mol. Cell , vol.9 , pp. 789-798
    • Hu, C.D.1    Chinenov, Y.2    Kerppola, T.K.3
  • 23
    • 0033604585 scopus 로고    scopus 로고
    • The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
    • Kandel, E. S., and N. Hay. 1999. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp. Cell Res. 253:210-229.
    • (1999) Exp. Cell Res. , vol.253 , pp. 210-229
    • Kandel, E.S.1    Hay, N.2
  • 24
    • 0024582782 scopus 로고
    • The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs
    • Kaufman, R. J., M. V. Davies, V. K. Pathak, and J. W. Hershey. 1989. The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs. Mol. Cell. Biol. 9:946-958.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 946-958
    • Kaufman, R.J.1    Davies, M.V.2    Pathak, V.K.3    Hershey, J.W.4
  • 25
    • 0034550280 scopus 로고    scopus 로고
    • The T cell antigen receptor activates phosphatidylinositol 3-kinase-regulated serine kinases protein kinase B and ribosomal S6 kinase 1
    • Lafont, V., E. Astoul, A. Laurence, J. Liautard, and D. Cantrell. 2000. The T cell antigen receptor activates phosphatidylinositol 3-kinase-regulated serine kinases protein kinase B and ribosomal S6 kinase 1. FEBS Lett. 486:38-42.
    • (2000) FEBS Lett. , vol.486 , pp. 38-42
    • Lafont, V.1    Astoul, E.2    Laurence, A.3    Liautard, J.4    Cantrell, D.5
  • 27
    • 0034845958 scopus 로고    scopus 로고
    • PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
    • Lawlor, M. A., and D. R. Alessi. 2001. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J. Cell Sci. 114:2903-2910.
    • (2001) J. Cell Sci. , vol.114 , pp. 2903-2910
    • Lawlor, M.A.1    Alessi, D.R.2
  • 28
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment
    • Lenardo, M., K. M. Chan, F. Hornung, H. McFarland, R. Siegel, J. Wang, and L. Zheng. 1999. Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment. Annu. Rev. Immunol. 17:221-253.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 221-253
    • Lenardo, M.1    Chan, K.M.2    Hornung, F.3    McFarland, H.4    Siegel, R.5    Wang, J.6    Zheng, L.7
  • 29
    • 0031539271 scopus 로고    scopus 로고
    • Ft1, a novel gene related to ubiquitin-conjugating enzymes, is deleted in the Fused toes mouse mutation
    • Lesche, R., A. Peetz, F. van der Hoeven, and U. Ruther. 1997. Ft1, a novel gene related to ubiquitin-conjugating enzymes, is deleted in the Fused toes mouse mutation. Mamm. Genome 8:879-883.
    • (1997) Mamm. Genome , vol.8 , pp. 879-883
    • Lesche, R.1    Peetz, A.2    Van Der Hoeven, F.3    Ruther, U.4
  • 30
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu, J., J. Farmer, Jr., W. S. Lane, J. Friedman, I. Weissman, and S. L. Schreiber. 1991. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66:807-815.
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer Jr., J.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 31
    • 0035850916 scopus 로고    scopus 로고
    • Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane
    • Maira, S. M., I. Galetic, D. P. Brazil, S. Kaech, E. Ingley, M. Thelen, and B. A. Hemmings. 2001. Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane. Science 294:374-380.
    • (2001) Science , vol.294 , pp. 374-380
    • Maira, S.M.1    Galetic, I.2    Brazil, D.P.3    Kaech, S.4    Ingley, E.5    Thelen, M.6    Hemmings, B.A.7
  • 33
    • 0031433362 scopus 로고    scopus 로고
    • An indirect effect of Stat5a in IL-2-induced proliferation: A critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction
    • Nakajima, H., X. W. Liu, A. Wynshaw-Boris, L. A. Rosenthal, K. Imada, D. S. Finbloom, L. Hennighausen, and W. J. Leonard. 1997. An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction. Immunity 7:691-701.
    • (1997) Immunity , vol.7 , pp. 691-701
    • Nakajima, H.1    Liu, X.W.2    Wynshaw-Boris, A.3    Rosenthal, L.A.4    Imada, K.5    Finbloom, D.S.6    Hennighausen, L.7    Leonard, W.J.8
  • 34
    • 0027172987 scopus 로고
    • Negative transcriptional regulation of human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT
    • Paliogianni, F., A. Raptis, S. S. Ahuja, S. M. Najjar, and D. T. Boumpas. 1993. Negative transcriptional regulation of human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT. J. Clin. Investig. 91:1481-1489.
    • (1993) J. Clin. Investig. , vol.91 , pp. 1481-1489
    • Paliogianni, F.1    Raptis, A.2    Ahuja, S.S.3    Najjar, S.M.4    Boumpas, D.T.5
  • 35
    • 0030686560 scopus 로고    scopus 로고
    • Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B
    • Parry, R. V., K. Reif, G. Smith, D. M. Sansom, B. A. Hemmings, and S. G. Ward. 1997. Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B. Eur. J. Immunol. 27:2495-2501.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2495-2501
    • Parry, R.V.1    Reif, K.2    Smith, G.3    Sansom, D.M.4    Hemmings, B.A.5    Ward, S.G.6
  • 36
    • 0034193568 scopus 로고    scopus 로고
    • Protein-protein interactions define specificity in signal transduction
    • Pawson, T., and P. Nash. 2000. Protein-protein interactions define specificity in signal transduction. Genes Dev. 14:1027-1047.
    • (2000) Genes Dev. , vol.14 , pp. 1027-1047
    • Pawson, T.1    Nash, P.2
  • 37
    • 0033565773 scopus 로고    scopus 로고
    • Kinase phosphorylation: Keeping it all in the family
    • Peterson, R. T., and S. L. Schreiber. 1999. Kinase phosphorylation: keeping it all in the family. Curr. Biol. 9:R521-R524.
    • (1999) Curr. Biol. , vol.9
    • Peterson, R.T.1    Schreiber, S.L.2
  • 38
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao, A., C. Luo, and P. G. Hogan. 1997. Transcription factors of the NFAT family: regulation and function. Annu. Rev. Immunol. 15:707-747.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 39
    • 0030908525 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase
    • Reif, K., B. M. Burgering, and D. A. Cantrell. 1997. Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase. J. Biol. Chem. 272:14426-14433.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14426-14433
    • Reif, K.1    Burgering, B.M.2    Cantrell, D.A.3
  • 40
    • 0031148668 scopus 로고    scopus 로고
    • A negative role for phosphoinositide 3-kinase in T-cell antigen receptor function
    • Reif, K., S. Lucas, and D. Cantrell. 1997. A negative role for phosphoinositide 3-kinase in T-cell antigen receptor function. Curr. Biol. 7:285-293.
    • (1997) Curr. Biol. , vol.7 , pp. 285-293
    • Reif, K.1    Lucas, S.2    Cantrell, D.3
  • 41
    • 1542375250 scopus 로고    scopus 로고
    • A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways
    • in press
    • Remy, I., and S. W. Michnick. A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways. Methods, in press.
    • Methods
    • Remy, I.1    Michnick, S.W.2
  • 42
    • 0034944377 scopus 로고    scopus 로고
    • Visualization of biochemical networks in living cells
    • Remy, I., and S. W. Michnick. 2001. Visualization of biochemical networks in living cells. Proc. Natl. Acad. Sci. USA 98:7678-7683.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7678-7683
    • Remy, I.1    Michnick, S.W.2
  • 43
    • 0008215320 scopus 로고    scopus 로고
    • Protein interactions and library screening with protein fragment complementation strategies
    • E. A. Golemis (ed.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Remy, I., J. N. Pelletier, A. Galarneau, and S. W. Michnick. 2001. Protein interactions and library screening with protein fragment complementation strategies, p. 449-475. In E. A. Golemis (ed.), Protein-protein interactions: a molecular cloning manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (2001) Protein-protein Interactions: A Molecular Cloning Manual , pp. 449-475
    • Remy, I.1    Pelletier, J.N.2    Galarneau, A.3    Michnick, S.W.4
  • 45
    • 0032101931 scopus 로고    scopus 로고
    • Autocrine and paracrine apoptosis are mediated by differential regulation of Fas ligand activity in two distinct Jurkat T cell populations
    • Su, X., J. Cheng, W. Liu, C. Liu, Z. Wang, P. Yang, T. Zhou, and J. D. Mountz. 1998. Autocrine and paracrine apoptosis are mediated by differential regulation of Fas ligand activity in two distinct Jurkat T cell populations. J. Immunol. 160:5288-5293.
    • (1998) J. Immunol. , vol.160 , pp. 5288-5293
    • Su, X.1    Cheng, J.2    Liu, W.3    Liu, C.4    Wang, Z.5    Yang, P.6    Zhou, T.7    Mountz, J.D.8
  • 46
    • 0034708482 scopus 로고    scopus 로고
    • Akt/Protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
    • Toker, A., and A. C. Newton. 2000. Akt/Protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site. J. Biol. Chem. 275:8271-8274.
    • (2000) J. Biol. Chem. , vol.275 , pp. 8271-8274
    • Toker, A.1    Newton, A.C.2
  • 48
    • 0034653608 scopus 로고    scopus 로고
    • The PI3K-PDK1 connection: More than just a road to PKB
    • Vanhaesebroeck, B., and D. R. Alessi. 2000. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 3:561-576.
    • (2000) Biochem. J. , vol.3 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 50
    • 0035967967 scopus 로고    scopus 로고
    • Signal transduction: Signaling specificity - A complex affair
    • Weston, C. R., and R. J. Davis. 2001. Signal transduction: signaling specificity - a complex affair. Science 292:2439-2440.
    • (2001) Science , vol.292 , pp. 2439-2440
    • Weston, C.R.1    Davis, R.J.2
  • 51
    • 18744373865 scopus 로고    scopus 로고
    • Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP
    • Yang, J., P. Cron, V. M. Good, V. Thompson, B. A. Hemmings, and D. Barford. 2002. Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP. Nat. Struct. Biol. 9:940-944.
    • (2002) Nat. Struct. Biol. , vol.9 , pp. 940-944
    • Yang, J.1    Cron, P.2    Good, V.M.3    Thompson, V.4    Hemmings, B.A.5    Barford, D.6
  • 52
    • 0036295728 scopus 로고    scopus 로고
    • Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation
    • Yang, J., P. Cron, V. Thompson, V. M. Good, D. Hess, B. A. Hemmings, and D. Barford. 2002. Molecular mechanism for the regulation of protein kinase B/ Akt by hydrophobic motif phosphorylation. Mol. Cell 9:1227-1240.
    • (2002) Mol. Cell , vol.9 , pp. 1227-1240
    • Yang, J.1    Cron, P.2    Thompson, V.3    Good, V.M.4    Hess, D.5    Hemmings, B.A.6    Barford, D.7


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