Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

Genome Biology

Volumn 17, Issue 1, 2016, Pages

  Genshaft, Alex S ^a,b,c   Li, Shuqiang ^c   Gallant, Caroline J ^e   Darmanis, Spyros ^e,f   Prakadan, Sanjay M ^a,b,c   Ziegler, Carly G K ^a,b,c   Lundberg, Martin ^g   Fredriksson, Simon ^g   Hong, Joyce ^h   Regev, Aviv ^b,c,f   Livak, Kenneth J ^d   Landegren, Ulf ^e   Shalek, Alex K ^a,b,c  

^a USA   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d FLUIDIGM CORPORATION   (United States)

^e UPPSALA UNIVERSITY   (Sweden)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^g Olink Biosciences   (Sweden)

^h Department of Electrical Engineering and Computer Science   (United States)

Author keywords

Metadata; Proximity extension assay; Single cell multi omics; Single cell proteomics; Single cell transcriptomics

Indexed keywords

CELL PROTEIN; COMPLEMENTARY DNA; DNA POLYMERASE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN; PROTEOME; RECOMBINANT PROTEIN; RNA DIRECTED DNA POLYMERASE; TRANSCRIPTOME; UNCLASSIFIED DRUG; RNA;

ADENOCARCINOMA CELL LINE; ANALYTIC METHOD; ANALYTICAL EQUIPMENT; ARTICLE; BREAST ADENOCARCINOMA; CELL LYSATE; CELL POPULATION; CONTROLLED STUDY; DILUTION; DNA SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IN SITU HYBRIDIZATION; MEASUREMENT; PROCEDURES CONCERNING CELLS; PROTEIN DETERMINATION; RNA ANALYSIS; BIOSYNTHESIS; BREAST TUMOR; FEMALE; GENE EXPRESSION PROFILING; GENETICS; PATHOLOGY; SINGLE CELL ANALYSIS;

BREAST NEOPLASMS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; PROTEOME; RNA; SINGLE-CELL ANALYSIS; TRANSCRIPTOME;

EID: 84988014533     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-1045-6     Document Type: Article

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