Screening for noise in gene expression identifies drug synergies

Science

Volumn 344, Issue 6190, 2014, Pages 1392-1396

  Dar, Roy D ^a   Hosmane, Nina N ^b   Arkin, Michelle R ^c   Siliciano, Robert F ^b,d   Weinberger, Leor S ^a,e,f  

^a GLADSTONE INSTITUTES   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CETIRIZINE; ENZYME ACTIVATOR; HISTONE DEACETYLASE INHIBITOR; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTRATIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VORINOSTAT; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; MOLECULAR LIBRARY;

DRUG; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS; NOISE; PHYSICAL ANALYSIS;

ARTICLE; CELL FATE; CYTOTOXICITY; DRUG POTENTIATION; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS; LATENT PERIOD; NOISE; PRIORITY JOURNAL; SCREENING; TRANSCRIPTION INITIATION; VIRUS REACTIVATION; DRUG DEVELOPMENT; DRUG EFFECTS; DRUG SCREENING; GENETIC SCREENING; GENETICS; HUMAN; MOLECULAR LIBRARY; PHARMACOLOGY; PHYSIOLOGY; PROMOTER REGION; STATISTICS; STATISTICS AND NUMERICAL DATA; VIRUS ACTIVATION;

ANTI-HIV AGENTS; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; GENE EXPRESSION; GENETIC TESTING; HIV; HUMANS; PROMOTER REGIONS, GENETIC; SMALL MOLECULE LIBRARIES; STOCHASTIC PROCESSES; VIRUS ACTIVATION;

EID: 84902665600     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1250220     Document Type: Article

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