-
1
-
-
84941010774
-
Targeting the IL-23/IL-17 axis for the treatment of psoriasis and psoriatic arthritis
-
COI: 1:CAS:528:DC%2BC2MXitV2nt7fL, PID: 26653110
-
Alunno A, Carubbi F, Cafaro G, Pucci G, Battista F, Bartoloni E, Giacomelli R, Schillaci G, Gerli R (2015) Targeting the IL-23/IL-17 axis for the treatment of psoriasis and psoriatic arthritis. Expert Opin Biol Ther 15:1727–1737
-
(2015)
Expert Opin Biol Ther
, vol.15
, pp. 1727-1737
-
-
Alunno, A.1
Carubbi, F.2
Cafaro, G.3
Pucci, G.4
Battista, F.5
Bartoloni, E.6
Giacomelli, R.7
Schillaci, G.8
Gerli, R.9
-
2
-
-
84878033103
-
Cytokines and T cells in atopic dermatitis
-
COI: 1:CAS:528:DC%2BC3sXptlOhtLg%3D, PID: 23608610
-
Auriemma M, Vianale G, Amerio P, Reale M (2013) Cytokines and T cells in atopic dermatitis. Eur Cytokine Netw 24:37–44
-
(2013)
Eur Cytokine Netw
, vol.24
, pp. 37-44
-
-
Auriemma, M.1
Vianale, G.2
Amerio, P.3
Reale, M.4
-
3
-
-
84925286890
-
Targeting the IL-17-T(H)17 pathway
-
COI: 1:CAS:528:DC%2BC2MXltFSn, PID: 25549584
-
Bartlett HS, Million RP (2015) Targeting the IL-17-T(H)17 pathway. Nat Rev Drug Discov 14:11–12
-
(2015)
Nat Rev Drug Discov
, vol.14
, pp. 11-12
-
-
Bartlett, H.S.1
Million, R.P.2
-
4
-
-
84975743646
-
IL-17 in chronic inflammation: from discovery to targeting
-
COI: 1:CAS:528:DC%2BC28XhtlSgs7w%3D, PID: 26837266
-
Beringer A, Noack M, Miossec P (2016) IL-17 in chronic inflammation: from discovery to targeting. Trends Mol Med 22:230–241
-
(2016)
Trends Mol Med
, vol.22
, pp. 230-241
-
-
Beringer, A.1
Noack, M.2
Miossec, P.3
-
5
-
-
33751180809
-
IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?
-
PID: 17083726
-
Bullens DM, Truyen E, Coteur L, Dilissen E, Hellings PW, Dupont LJ, Ceuppens JL (2006) IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir Res 7:135
-
(2006)
Respir Res
, vol.7
, pp. 135
-
-
Bullens, D.M.1
Truyen, E.2
Coteur, L.3
Dilissen, E.4
Hellings, P.W.5
Dupont, L.J.6
Ceuppens, J.L.7
-
6
-
-
84961792836
-
A review of biologic therapies targeting IL-23 and IL-17 for use in moderate-to-severe plaque psoriasis
-
Campa M, Mansouri B, Warren R, Menter A (2016) A review of biologic therapies targeting IL-23 and IL-17 for use in moderate-to-severe plaque psoriasis. Dermatol Ther 6:1–12
-
(2016)
Dermatol Ther
, vol.6
, pp. 1-12
-
-
Campa, M.1
Mansouri, B.2
Warren, R.3
Menter, A.4
-
7
-
-
0032939156
-
Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
-
COI: 1:CAS:528:DyaK1MXjtlKjurs%3D, PID: 10323452
-
Chabaud M, Durand JM, Buchs N, Fossiez F, Page G, Frappart L, Miossec P (1999) Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum 42:963–970
-
(1999)
Arthritis Rheum
, vol.42
, pp. 963-970
-
-
Chabaud, M.1
Durand, J.M.2
Buchs, N.3
Fossiez, F.4
Page, G.5
Frappart, L.6
Miossec, P.7
-
8
-
-
0035889931
-
Enhancing effect of IL-1, IL-17, and TNF-alpha on macrophage inflammatory protein-3alpha production in rheumatoid arthritis: regulation by soluble receptors and Th2 cytokines
-
COI: 1:CAS:528:DC%2BD3MXotlalsrg%3D, PID: 11698482
-
Chabaud M, Page G, Miossec P (2001) Enhancing effect of IL-1, IL-17, and TNF-alpha on macrophage inflammatory protein-3alpha production in rheumatoid arthritis: regulation by soluble receptors and Th2 cytokines. J Immunol 167:6015–6020
-
(2001)
J Immunol
, vol.167
, pp. 6015-6020
-
-
Chabaud, M.1
Page, G.2
Miossec, P.3
-
9
-
-
77950420796
-
Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis
-
COI: 1:CAS:528:DC%2BC3cXktFKhsLg%3D, PID: 20212110
-
Chae WJ, Gibson TF, Zelterman D, Hao L, Henegariu O, Bothwell AL (2010) Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis. Proc Natl Acad Sci USA 107:5540–5544
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5540-5544
-
-
Chae, W.J.1
Gibson, T.F.2
Zelterman, D.3
Hao, L.4
Henegariu, O.5
Bothwell, A.L.6
-
10
-
-
77951529848
-
Therapeutic antibodies for autoimmunity and inflammation
-
COI: 1:CAS:528:DC%2BC3cXltV2lu7k%3D, PID: 20414204
-
Chan AC, Carter PJ (2010) Therapeutic antibodies for autoimmunity and inflammation. Nat Rev Immunol 10:301–316
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 301-316
-
-
Chan, A.C.1
Carter, P.J.2
-
11
-
-
34248574863
-
A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses
-
PID: 17452998
-
Chang SH, Dong C (2007) A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses. Cell Res 17:435–440
-
(2007)
Cell Res
, vol.17
, pp. 435-440
-
-
Chang, S.H.1
Dong, C.2
-
12
-
-
33846022750
-
Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor
-
COI: 1:CAS:528:DC%2BD28Xht1ajtrrO, PID: 17035243
-
Chang SH, Park H, Dong C (2006) Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor. J Biol Chem 281:35603–35607
-
(2006)
J Biol Chem
, vol.281
, pp. 35603-35607
-
-
Chang, S.H.1
Park, H.2
Dong, C.3
-
13
-
-
80755133721
-
Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E
-
COI: 1:CAS:528:DC%2BC3MXhtlyjs73O, PID: 21982598
-
Chang SH, Reynolds JM, Pappu BP, Chen G, Martinez GJ, Dong C (2011) Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E. Immunity 35:611–621
-
(2011)
Immunity
, vol.35
, pp. 611-621
-
-
Chang, S.H.1
Reynolds, J.M.2
Pappu, B.P.3
Chen, G.4
Martinez, G.J.5
Dong, C.6
-
14
-
-
84898777944
-
T helper 17 cells play a critical pathogenic role in lung cancer
-
COI: 1:CAS:528:DC%2BC2cXltl2lsbo%3D, PID: 24706787
-
Chang SH, Mirabolfathinejad SG, Katta H, Cumpian AM, Gong L, Caetano MS, Moghaddam SJ, Dong C (2014) T helper 17 cells play a critical pathogenic role in lung cancer. Proc Natl Acad Sci USA 111:5664–5669
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 5664-5669
-
-
Chang, S.H.1
Mirabolfathinejad, S.G.2
Katta, H.3
Cumpian, A.M.4
Gong, L.5
Caetano, M.S.6
Moghaddam, S.J.7
Dong, C.8
-
15
-
-
84896287860
-
Absence of interleukin-17 receptor a signaling prevents autoimmune inflammation of the joint and leads to a Th2-like phenotype in collagen-induced arthritis
-
COI: 1:CAS:528:DC%2BC2cXhtl2gt7vN, PID: 24504806
-
Corneth OB, Mus AM, Asmawidjaja PS, Klein Wolterink RG, van Nimwegen M, Brem MD, Hofman Y, Hendriks RW, Lubberts E (2014) Absence of interleukin-17 receptor a signaling prevents autoimmune inflammation of the joint and leads to a Th2-like phenotype in collagen-induced arthritis. Arthritis Rheumatol 66:340–349
-
(2014)
Arthritis Rheumatol
, vol.66
, pp. 340-349
-
-
Corneth, O.B.1
Mus, A.M.2
Asmawidjaja, P.S.3
Klein Wolterink, R.G.4
van Nimwegen, M.5
Brem, M.D.6
Hofman, Y.7
Hendriks, R.W.8
Lubberts, E.9
-
16
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
COI: 1:CAS:528:DC%2BD3sXhsV2rsbs%3D, PID: 12610626
-
Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein RA, Sedgwick JD (2003) Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421:744–748
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
Zurawski, S.11
Wiekowski, M.12
Lira, S.A.13
Gorman, D.14
Kastelein, R.A.15
Sedgwick, J.D.16
-
17
-
-
53949099427
-
A role for Th17 cells in the immunopathogenesis of atopic dermatitis?
-
PID: 18927538
-
Di Cesare A, Di Meglio P, Nestle FO (2008) A role for Th17 cells in the immunopathogenesis of atopic dermatitis? J Invest Dermatol 128:2569–2571
-
(2008)
J Invest Dermatol
, vol.128
, pp. 2569-2571
-
-
Di Cesare, A.1
Di Meglio, P.2
Nestle, F.O.3
-
18
-
-
34249030920
-
Western regional research alliance for pediatric IBD, IL-23 receptor (IL-23R) gene protects against pediatric crohn’s disease
-
PID: 17309073
-
Dubinsky MC, Wang D, Picornell Y, Wrobel I, Katzir L, Quiros A, Dutridge D, Wahbeh G, Silber G, Bahar R, Mengesha E, Targan SR, Taylor KD, Rotter JI (2007) Western regional research alliance for pediatric IBD, IL-23 receptor (IL-23R) gene protects against pediatric crohn’s disease. Inflamm Bowel Dis 13:511–515
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 511-515
-
-
Dubinsky, M.C.1
Wang, D.2
Picornell, Y.3
Wrobel, I.4
Katzir, L.5
Quiros, A.6
Dutridge, D.7
Wahbeh, G.8
Silber, G.9
Bahar, R.10
Mengesha, E.11
Targan, S.R.12
Taylor, K.D.13
Rotter, J.I.14
-
19
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
COI: 1:CAS:528:DC%2BD28Xht1CntrjF, PID: 17068223
-
Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, Kistner EO, Schumm LP, Lee AT, Gregersen PK, Barmada MM, Rotter JI, Nicolae DL, Cho JH (2006) A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314:1461–1463
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
Dassopoulos, T.11
Bitton, A.12
Yang, H.13
Targan, S.14
Datta, L.W.15
Kistner, E.O.16
Schumm, L.P.17
Lee, A.T.18
Gregersen, P.K.19
Barmada, M.M.20
Rotter, J.I.21
Nicolae, D.L.22
Cho, J.H.23
more..
-
20
-
-
84947554133
-
Targeting IL-17 with ixekizumab in patients with psoriasis
-
COI: 1:CAS:528:DC%2BC2MXhvVehs73I, PID: 26569072
-
Dyring-Andersen B, Skov L, Zachariae C (2015) Targeting IL-17 with ixekizumab in patients with psoriasis. Immunotherapy 7:957–966
-
(2015)
Immunotherapy
, vol.7
, pp. 957-966
-
-
Dyring-Andersen, B.1
Skov, L.2
Zachariae, C.3
-
21
-
-
84975815496
-
Brodalumab for the treatment of psoriasis: a review of phase III trials
-
Farahnik B, Beroukhim K, Abrouk M, Nakamura M, Zhu TH, Singh R, Lee K, Bhutani T, Koo J (2016) Brodalumab for the treatment of psoriasis: a review of phase III trials. Dermatol Ther (Heidelb) 6(2):111–124
-
(2016)
Dermatol Ther (Heidelb)
, vol.6
, Issue.2
, pp. 111-124
-
-
Farahnik, B.1
Beroukhim, K.2
Abrouk, M.3
Nakamura, M.4
Zhu, T.H.5
Singh, R.6
Lee, K.7
Bhutani, T.8
Koo, J.9
-
22
-
-
15844402155
-
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
-
COI: 1:CAS:528:DyaK28Xjslaisbk%3D, PID: 8676080
-
Fossiez F, Djossou O, Chomarat P, Flores-Romo L, Ait-Yahia S, Maat C, Pin JJ, Garrone P, Garcia E, Saeland S, Blanchard D, Gaillard C, Das Mahapatra B, Rouvier E, Golstein P, Banchereau J, Lebecque S (1996) T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J Exp Med 183:2593–2603
-
(1996)
J Exp Med
, vol.183
, pp. 2593-2603
-
-
Fossiez, F.1
Djossou, O.2
Chomarat, P.3
Flores-Romo, L.4
Ait-Yahia, S.5
Maat, C.6
Pin, J.J.7
Garrone, P.8
Garcia, E.9
Saeland, S.10
Blanchard, D.11
Gaillard, C.12
Das Mahapatra, B.13
Rouvier, E.14
Golstein, P.15
Banchereau, J.16
Lebecque, S.17
-
23
-
-
84906535154
-
The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing
-
COI: 1:CAS:528:DC%2BC2cXhsVSit7%2FL, PID: 25145755
-
Gaffen SL, Jain R, Garg AV, Cua DJ (2014) The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing. Nat Rev Immunol 14:585–600
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 585-600
-
-
Gaffen, S.L.1
Jain, R.2
Garg, A.V.3
Cua, D.J.4
-
24
-
-
0041833336
-
HLA is a candidate region for psoriatic arthritis. evidence for excessive HLA sharing in sibling pairs
-
COI: 1:CAS:528:DC%2BD3sXms1yntro%3D, PID: 12941544
-
Gladman DD, Farewell VT, Pellett F, Schentag C, Rahman P (2003) HLA is a candidate region for psoriatic arthritis. evidence for excessive HLA sharing in sibling pairs. Hum Immunol 64:887–889
-
(2003)
Hum Immunol
, vol.64
, pp. 887-889
-
-
Gladman, D.D.1
Farewell, V.T.2
Pellett, F.3
Schentag, C.4
Rahman, P.5
-
25
-
-
58149198187
-
Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis
-
COI: 1:CAS:528:DC%2BD1cXhtlaisrbK, PID: 18981165
-
Guttman-Yassky E, Lowes MA, Fuentes-Duculan J, Zaba LC, Cardinale I, Nograles KE, Khatcherian A, Novitskaya I, Carucci JA, Bergman R, Krueger JG (2008) Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis. J Immunol 181:7420–7427
-
(2008)
J Immunol
, vol.181
, pp. 7420-7427
-
-
Guttman-Yassky, E.1
Lowes, M.A.2
Fuentes-Duculan, J.3
Zaba, L.C.4
Cardinale, I.5
Nograles, K.E.6
Khatcherian, A.7
Novitskaya, I.8
Carucci, J.A.9
Bergman, R.10
Krueger, J.G.11
-
26
-
-
61749093508
-
IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice
-
COI: 1:CAS:528:DC%2BD1MXmtFChsw%3D%3D, PID: 19075395
-
Haak S, Croxford AL, Kreymborg K, Heppner FL, Pouly S, Becher B, Waisman A (2009) IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice. J Clin Invest 119:61–69
-
(2009)
J Clin Invest
, vol.119
, pp. 61-69
-
-
Haak, S.1
Croxford, A.L.2
Kreymborg, K.3
Heppner, F.L.4
Pouly, S.5
Becher, B.6
Waisman, A.7
-
27
-
-
70349753261
-
Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis
-
COI: 1:CAS:528:DC%2BD1MXhtF2qsLrI, PID: 19295614
-
Harper EG, Guo C, Rizzo H, Lillis JV, Kurtz SE, Skorcheva I, Purdy D, Fitch E, Iordanov M, Blauvelt A (2009) Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis. J Invest Dermatol 129:2175–2183
-
(2009)
J Invest Dermatol
, vol.129
, pp. 2175-2183
-
-
Harper, E.G.1
Guo, C.2
Rizzo, H.3
Lillis, J.V.4
Kurtz, S.E.5
Skorcheva, I.6
Purdy, D.7
Fitch, E.8
Iordanov, M.9
Blauvelt, A.10
-
28
-
-
79951581559
-
Decrease in circulating Th17 cells correlates with increased levels of CCL17, IgE and eosinophils in atopic dermatitis
-
COI: 1:CAS:528:DC%2BC3MXit1ajtbs%3D, PID: 21255981
-
Hayashida S, Uchi H, Moroi Y, Furue M (2011) Decrease in circulating Th17 cells correlates with increased levels of CCL17, IgE and eosinophils in atopic dermatitis. J Dermatol Sci 61:180–186
-
(2011)
J Dermatol Sci
, vol.61
, pp. 180-186
-
-
Hayashida, S.1
Uchi, H.2
Moroi, Y.3
Furue, M.4
-
29
-
-
33750505009
-
Interleukin-23 drives innate and T cell-mediated intestinal inflammation
-
COI: 1:CAS:528:DC%2BD28XhtFGqtL7I, PID: 17030949
-
Hue S, Ahern P, Buonocore S, Kullberg MC, Cua DJ, McKenzie BS, Powrie F, Maloy KJ (2006) Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med 203:2473–2483
-
(2006)
J Exp Med
, vol.203
, pp. 2473-2483
-
-
Hue, S.1
Ahern, P.2
Buonocore, S.3
Kullberg, M.C.4
Cua, D.J.5
McKenzie, B.S.6
Powrie, F.7
Maloy, K.J.8
-
30
-
-
77958072084
-
Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
-
PID: 20926833
-
Hueber W, Patel DD, Dryja T, Wright AM, Koroleva I, Bruin G, Antoni C, Draelos Z, Gold MH, Psoriasis Study G, Durez P, Tak PP, Gomez-Reino JJ, Rheumatoid Arthritis Study G, Foster CS, Kim RY, Samson CM, Falk NS, Chu DS, Callanan D, Nguyen QD, Uveitis Study G, Rose K, Haider A, Di Padova F (2010) Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med 2:52ra72
-
(2010)
Sci Transl Med
, vol.2
, pp. 52ra72
-
-
Hueber, W.1
Patel, D.D.2
Dryja, T.3
Wright, A.M.4
Koroleva, I.5
Bruin, G.6
Antoni, C.7
Draelos, Z.8
Gold, M.H.9
Psoriasis Study, G.10
Durez, P.11
Tak, P.P.12
Gomez-Reino, J.J.13
Rheumatoid Arthritis Study, G.14
Foster, C.S.15
Kim, R.Y.16
Samson, C.M.17
Falk, N.S.18
Chu, D.S.19
Callanan, D.20
Nguyen, Q.D.21
Uveitis Study, G.22
Rose, K.23
Haider, A.24
Di Padova, F.25
more..
-
31
-
-
79955538365
-
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing ROR gammat activity
-
COI: 1:CAS:528:DC%2BC3MXjvVOisr8%3D, PID: 21441909
-
Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR (2011) Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing ROR gammat activity. Nature 472:486–490
-
(2011)
Nature
, vol.472
, pp. 486-490
-
-
Huh, J.R.1
Leung, M.W.2
Huang, P.3
Ryan, D.A.4
Krout, M.R.5
Malapaka, R.R.6
Chow, J.7
Manel, N.8
Ciofani, M.9
Kim, S.V.10
Cuesta, A.11
Santori, F.R.12
Lafaille, J.J.13
Xu, H.E.14
Gin, D.Y.15
Rastinejad, F.16
Littman, D.R.17
-
32
-
-
84906316949
-
Inhibiting ROR gammat/Th17 axis for autoimmune disorders
-
COI: 1:CAS:528:DC%2BC2cXotVeitbc%3D, PID: 24792721
-
Isono F, Fujita-Sato S, Ito S (2014) Inhibiting ROR gammat/Th17 axis for autoimmune disorders. Drug Discov Today 19:1205–1211
-
(2014)
Drug Discov Today
, vol.19
, pp. 1205-1211
-
-
Isono, F.1
Fujita-Sato, S.2
Ito, S.3
-
33
-
-
33748588423
-
The orphan nuclear receptor ROR gammat directs the differentiation program of proinflammatory IL-17 + T helper cells
-
COI: 1:CAS:528:DC%2BD28XhtVCnsrrE, PID: 16990136
-
Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR (2006) The orphan nuclear receptor ROR gammat directs the differentiation program of proinflammatory IL-17 + T helper cells. Cell 126:1121–1133
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
34
-
-
79951743212
-
Functional specialization of interleukin-17 family members
-
COI: 1:CAS:528:DC%2BC3MXisVKisLY%3D, PID: 21349428
-
Iwakura Y, Ishigame H, Saijo S, Nakae S (2011) Functional specialization of interleukin-17 family members. Immunity 34:149–162
-
(2011)
Immunity
, vol.34
, pp. 149-162
-
-
Iwakura, Y.1
Ishigame, H.2
Saijo, S.3
Nakae, S.4
-
35
-
-
41549160626
-
Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis
-
COI: 1:CAS:528:DC%2BD1cXkvV2itL4%3D, PID: 18400195
-
Izcue A, Hue S, Buonocore S, Arancibia-Carcamo CV, Ahern PP, Iwakura Y, Maloy KJ, Powrie F (2008) Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis. Immunity 28:559–570
-
(2008)
Immunity
, vol.28
, pp. 559-570
-
-
Izcue, A.1
Hue, S.2
Buonocore, S.3
Arancibia-Carcamo, C.V.4
Ahern, P.P.5
Iwakura, Y.6
Maloy, K.J.7
Powrie, F.8
-
36
-
-
49449115544
-
Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides
-
PID: 18668556
-
Jandus C, Bioley G, Rivals JP, Dudler J, Speiser D, Romero P (2008) Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides. Arthritis Rheum 58:2307–2317
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2307-2317
-
-
Jandus, C.1
Bioley, G.2
Rivals, J.P.3
Dudler, J.4
Speiser, D.5
Romero, P.6
-
37
-
-
58349105187
-
Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin
-
COI: 1:CAS:528:DC%2BD1MXjtFGgsr4%3D, PID: 19016708
-
Johansen C, Usher PA, Kjellerup RB, Lundsgaard D, Iversen L, Kragballe K (2009) Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin. Br J Dermatol 160:319–324
-
(2009)
Br J Dermatol
, vol.160
, pp. 319-324
-
-
Johansen, C.1
Usher, P.A.2
Kjellerup, R.B.3
Lundsgaard, D.4
Iversen, L.5
Kragballe, K.6
-
38
-
-
56549104968
-
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn’s disease
-
COI: 1:CAS:528:DC%2BD1cXhsFCrsrnN, PID: 18653729
-
Kobayashi T, Okamoto S, Hisamatsu T, Kamada N, Chinen H, Saito R, Kitazume MT, Nakazawa A, Sugita A, Koganei K, Isobe K, Hibi T (2008) IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn’s disease. Gut 57:1682–1689
-
(2008)
Gut
, vol.57
, pp. 1682-1689
-
-
Kobayashi, T.1
Okamoto, S.2
Hisamatsu, T.3
Kamada, N.4
Chinen, H.5
Saito, R.6
Kitazume, M.T.7
Nakazawa, A.8
Sugita, A.9
Koganei, K.10
Isobe, K.11
Hibi, T.12
-
39
-
-
84939958120
-
Novel therapeutic targets in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC2MXivVSgsbo%3D, PID: 25732812
-
Koenders MI, van den Berg WB (2015) Novel therapeutic targets in rheumatoid arthritis. Trends Pharmacol Sci 36:189–195
-
(2015)
Trends Pharmacol Sci
, vol.36
, pp. 189-195
-
-
Koenders, M.I.1
van den Berg, W.B.2
-
40
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
COI: 1:CAS:528:DyaK1MXivFans7c%3D, PID: 10225978
-
Kotake S, Udagawa N, Takahashi N, Matsuzaki K, Itoh K, Ishiyama S, Saito S, Inoue K, Kamatani N, Gillespie MT, Martin TJ, Suda T (1999) IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 103:1345–1352
-
(1999)
J Clin Invest
, vol.103
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
Matsuzaki, K.4
Itoh, K.5
Ishiyama, S.6
Saito, S.7
Inoue, K.8
Kamatani, N.9
Gillespie, M.T.10
Martin, T.J.11
Suda, T.12
-
41
-
-
40049103352
-
IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis
-
COI: 1:CAS:528:DC%2BD2sXhtlyitrbN, PID: 18056351
-
Kreymborg K, Etzensperger R, Dumoutier L, Haak S, Rebollo A, Buch T, Heppner FL, Renauld JC, Becher B (2007) IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis. J Immunol 179:8098–8104
-
(2007)
J Immunol
, vol.179
, pp. 8098-8104
-
-
Kreymborg, K.1
Etzensperger, R.2
Dumoutier, L.3
Haak, S.4
Rebollo, A.5
Buch, T.6
Heppner, F.L.7
Renauld, J.C.8
Becher, B.9
-
42
-
-
67651094058
-
Endogenous IL-17 contributes to reduced tumor growth and metastasis
-
COI: 1:CAS:528:DC%2BD1MXovVKlsr0%3D, PID: 19289853
-
Kryczek I, Wei S, Szeliga W, Vatan L, Zou W (2009) Endogenous IL-17 contributes to reduced tumor growth and metastasis. Blood 114:357–359
-
(2009)
Blood
, vol.114
, pp. 357-359
-
-
Kryczek, I.1
Wei, S.2
Szeliga, W.3
Vatan, L.4
Zou, W.5
-
43
-
-
84944675546
-
Interleukin-23-independent IL-17 production regulates intestinal epithelial permeability
-
COI: 1:CAS:528:DC%2BC2MXhsFyqt7vO, PID: 26431948
-
Lee JS, Tato CM, Joyce-Shaikh B, Gulen MF, Cayatte C, Chen Y, Blumenschein WM, Judo M, Ayanoglu G, McClanahan TK, Li X, Cua DJ (2015) Interleukin-23-independent IL-17 production regulates intestinal epithelial permeability. Immunity 43:727–738
-
(2015)
Immunity
, vol.43
, pp. 727-738
-
-
Lee, J.S.1
Tato, C.M.2
Joyce-Shaikh, B.3
Gulen, M.F.4
Cayatte, C.5
Chen, Y.6
Blumenschein, W.M.7
Judo, M.8
Ayanoglu, G.9
McClanahan, T.K.10
Li, X.11
Cua, D.J.12
-
44
-
-
71649102974
-
IL-23 induces receptor activator of NF-kappaB ligand expression in fibroblast-like synoviocytes via STAT3 and NF-kappaB signal pathways
-
COI: 1:CAS:528:DC%2BD1MXhsFyitLnI, PID: 19900478
-
Li X, Kim KW, Cho ML, Ju JH, Kang CM, Oh HJ, Min JK, Lee SH, Park SH, Kim HY (2010) IL-23 induces receptor activator of NF-kappaB ligand expression in fibroblast-like synoviocytes via STAT3 and NF-kappaB signal pathways. Immunol Lett 127:100–107
-
(2010)
Immunol Lett
, vol.127
, pp. 100-107
-
-
Li, X.1
Kim, K.W.2
Cho, M.L.3
Ju, J.H.4
Kang, C.M.5
Oh, H.J.6
Min, J.K.7
Lee, S.H.8
Park, S.H.9
Kim, H.Y.10
-
45
-
-
84892467822
-
Proatherogenic conditions promote autoimmune T helper 17 cell responses in vivo
-
COI: 1:CAS:528:DC%2BC2cXnt12jsg%3D%3D, PID: 24412615
-
Lim H, Kim YU, Sun H, Lee JH, Reynolds JM, Hanabuchi S, Wu H, Teng BB, Chung Y (2014) Proatherogenic conditions promote autoimmune T helper 17 cell responses in vivo. Immunity 40:153–165
-
(2014)
Immunity
, vol.40
, pp. 153-165
-
-
Lim, H.1
Kim, Y.U.2
Sun, H.3
Lee, J.H.4
Reynolds, J.M.5
Hanabuchi, S.6
Wu, H.7
Teng, B.B.8
Chung, Y.9
-
46
-
-
38449085921
-
A role for the cytoplasmic adaptor protein Act1 in mediating IL-17 signaling
-
Linden A (2007) A role for the cytoplasmic adaptor protein Act1 in mediating IL-17 signaling. Sci STKE 2007(398):4
-
(2007)
Sci STKE
, vol.2007
, Issue.398
, pp. 4
-
-
Linden, A.1
-
47
-
-
77953654056
-
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling
-
PID: 19825828
-
Liu C, Qian W, Qian Y, Giltiay NV, Lu Y, Swaidani S, Misra S, Deng L, Chen ZJ, Li X (2009) Act1, a U-box E3 ubiquitin ligase for IL-17 signaling. Sci Signal 2:ra63
-
(2009)
Sci Signal
, vol.2
, pp. ra63
-
-
Liu, C.1
Qian, W.2
Qian, Y.3
Giltiay, N.V.4
Lu, Y.5
Swaidani, S.6
Misra, S.7
Deng, L.8
Chen, Z.J.9
Li, X.10
-
48
-
-
84875864504
-
The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses
-
COI: 1:CAS:528:DC%2BC3sXjvFSrsw%3D%3D, PID: 23291100
-
Lowes MA, Russell CB, Martin DA, Towne JE, Krueger JG (2013) The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses. Trends Immunol 34:174–181
-
(2013)
Trends Immunol
, vol.34
, pp. 174-181
-
-
Lowes, M.A.1
Russell, C.B.2
Martin, D.A.3
Towne, J.E.4
Krueger, J.G.5
-
49
-
-
84933672236
-
The IL-23-IL-17 axis in inflammatory arthritis
-
PID: 26369609
-
Lubberts E (2015) The IL-23-IL-17 axis in inflammatory arthritis. Nat Rev Rheumatol 11:562
-
(2015)
Nat Rev Rheumatol
, vol.11
, pp. 562
-
-
Lubberts, E.1
-
50
-
-
84958154941
-
The emerging roles of gamma-delta T cells in tissue inflammation in experimental autoimmune encephalomyelitis
-
PID: 26858718
-
Malik S, Want MY, Awasthi A (2016) The emerging roles of gamma-delta T cells in tissue inflammation in experimental autoimmune encephalomyelitis. Front Immunol 7:14
-
(2016)
Front Immunol
, vol.7
, pp. 14
-
-
Malik, S.1
Want, M.Y.2
Awasthi, A.3
-
51
-
-
67650684023
-
The IL-17/IL-23 axis of inflammation in cancer: friend or foe?
-
COI: 1:CAS:528:DC%2BC3cXnt1Khsrs%3D, PID: 19513943
-
Martin-Orozco N, Dong C (2009) The IL-17/IL-23 axis of inflammation in cancer: friend or foe? Curr Opin Investig Drugs 10:543–549
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 543-549
-
-
Martin-Orozco, N.1
Dong, C.2
-
52
-
-
70449530422
-
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
-
COI: 1:CAS:528:DC%2BD1MXhsFylsbjJ, PID: 19879162
-
Martin-Orozco N, Muranski P, Chung Y, Yang XO, Yamazaki T, Lu S, Hwu P, Restifo NP, Overwijk WW, Dong C (2009) T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 31:787–798
-
(2009)
Immunity
, vol.31
, pp. 787-798
-
-
Martin-Orozco, N.1
Muranski, P.2
Chung, Y.3
Yang, X.O.4
Yamazaki, T.5
Lu, S.6
Hwu, P.7
Restifo, N.P.8
Overwijk, W.W.9
Dong, C.10
-
53
-
-
21244455537
-
Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis
-
COI: 1:CAS:528:DC%2BD2MXltlymsr8%3D, PID: 15972674
-
McAllister F, Henry A, Kreindler JL, Dubin PJ, Ulrich L, Steele C, Finder JD, Pilewski JM, Carreno BM, Goldman SJ, Pirhonen J, Kolls JK (2005) Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J Immunol 175:404–412
-
(2005)
J Immunol
, vol.175
, pp. 404-412
-
-
McAllister, F.1
Henry, A.2
Kreindler, J.L.3
Dubin, P.J.4
Ulrich, L.5
Steele, C.6
Finder, J.D.7
Pilewski, J.M.8
Carreno, B.M.9
Goldman, S.J.10
Pirhonen, J.11
Kolls, J.K.12
-
54
-
-
79954450170
-
Increased serum IL-17 and IL-23 in the patient with ankylosing spondylitis
-
PID: 21161669
-
Mei Y, Pan F, Gao J, Ge R, Duan Z, Zeng Z, Liao F, Xia G, Wang S, Xu S, Xu J, Zhang L, Ye D (2011) Increased serum IL-17 and IL-23 in the patient with ankylosing spondylitis. Clin Rheumatol 30:269–273
-
(2011)
Clin Rheumatol
, vol.30
, pp. 269-273
-
-
Mei, Y.1
Pan, F.2
Gao, J.3
Ge, R.4
Duan, Z.5
Zeng, Z.6
Liao, F.7
Xia, G.8
Wang, S.9
Xu, S.10
Xu, J.11
Zhang, L.12
Ye, D.13
-
55
-
-
84899717815
-
Interleukin-17+ CD8 +T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression
-
COI: 1:CAS:528:DC%2BC2cXhtlyktLfE, PID: 24470327
-
Menon B, Gullick NJ, Walter GJ, Rajasekhar M, Garrood T, Evans HG, Taams LS, Kirkham BW (2014) Interleukin-17+ CD8 +T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression. Arthritis Rheumatol 66:1272–1281
-
(2014)
Arthritis Rheumatol
, vol.66
, pp. 1272-1281
-
-
Menon, B.1
Gullick, N.J.2
Walter, G.J.3
Rajasekhar, M.4
Garrood, T.5
Evans, H.G.6
Taams, L.S.7
Kirkham, B.W.8
-
56
-
-
80052611560
-
Serum and synovial fluid levels of interleukin-17 in correlation with disease activity in patients with RA
-
PID: 21874405
-
Metawi SA, Abbas D, Kamal MM, Ibrahim MK (2011) Serum and synovial fluid levels of interleukin-17 in correlation with disease activity in patients with RA. Clin Rheumatol 30:1201–1207
-
(2011)
Clin Rheumatol
, vol.30
, pp. 1201-1207
-
-
Metawi, S.A.1
Abbas, D.2
Kamal, M.M.3
Ibrahim, M.K.4
-
57
-
-
69349093225
-
Interleukin-17 and type 17 helper T cells
-
COI: 1:CAS:528:DC%2BD1MXhtVKhtLrP, PID: 19710487
-
Miossec P, Korn T, Kuchroo VK (2009) Interleukin-17 and type 17 helper T cells. N Engl J Med 361:888–898
-
(2009)
N Engl J Med
, vol.361
, pp. 888-898
-
-
Miossec, P.1
Korn, T.2
Kuchroo, V.K.3
-
58
-
-
0034833339
-
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
-
COI: 1:CAS:528:DC%2BD3MXnsFGntb8%3D, PID: 11544464
-
Molet S, Hamid Q, Davoine F, Nutku E, Taha R, Page N, Olivenstein R, Elias J, Chakir J (2001) IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 108:430–438
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 430-438
-
-
Molet, S.1
Hamid, Q.2
Davoine, F.3
Nutku, E.4
Taha, R.5
Page, N.6
Olivenstein, R.7
Elias, J.8
Chakir, J.9
-
59
-
-
47649122633
-
Tumor-specific Th17-polarized cells eradicate large established melanoma
-
COI: 1:CAS:528:DC%2BD1cXos1Cit70%3D, PID: 18354038
-
Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, Paulos CM, Palmer DC, Touloukian CE, Ptak K, Gattinoni L, Wrzesinski C, Hinrichs CS, Kerstann KW, Feigenbaum L, Chan CC, Restifo NP (2008) Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood 112:362–373
-
(2008)
Blood
, vol.112
, pp. 362-373
-
-
Muranski, P.1
Boni, A.2
Antony, P.A.3
Cassard, L.4
Irvine, K.R.5
Kaiser, A.6
Paulos, C.M.7
Palmer, D.C.8
Touloukian, C.E.9
Ptak, K.10
Gattinoni, L.11
Wrzesinski, C.12
Hinrichs, C.S.13
Kerstann, K.W.14
Feigenbaum, L.15
Chan, C.C.16
Restifo, N.P.17
-
60
-
-
0346962972
-
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
COI: 1:CAS:528:DC%2BD3sXpvFakur4%3D, PID: 14662908
-
Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, Sedgwick JD, Cua DJ (2003) Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 198:1951–1957
-
(2003)
J Exp Med
, vol.198
, pp. 1951-1957
-
-
Murphy, C.A.1
Langrish, C.L.2
Chen, Y.3
Blumenschein, W.4
McClanahan, T.5
Kastelein, R.A.6
Sedgwick, J.D.7
Cua, D.J.8
-
61
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
COI: 1:CAS:528:DC%2BD3sXptFOktrg%3D, PID: 14634133
-
Nakae S, Nambu A, Sudo K, Iwakura Y (2003) Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 171:6173–6177
-
(2003)
J Immunol
, vol.171
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
62
-
-
84917742054
-
The A/A genotype of an interleukin-17A polymorphism predisposes to increased severity of atopic dermatitis and coexistence with asthma
-
COI: 1:STN:280:DC%2BC2M7hsVylsQ%3D%3D, PID: 25223230
-
Narbutt J, Wojtczak M, Zalinska A, Salinski A, Przybylowska-Sygut K, Kuna P, Majak P, Sysa-Jedrzejowska A, Lesiak A (2015) The A/A genotype of an interleukin-17A polymorphism predisposes to increased severity of atopic dermatitis and coexistence with asthma. Clin Exp Dermatol 40:11–16
-
(2015)
Clin Exp Dermatol
, vol.40
, pp. 11-16
-
-
Narbutt, J.1
Wojtczak, M.2
Zalinska, A.3
Salinski, A.4
Przybylowska-Sygut, K.5
Kuna, P.6
Majak, P.7
Sysa-Jedrzejowska, A.8
Lesiak, A.9
-
63
-
-
0038741846
-
The STIR-domain superfamily in signal transduction, development and immunity
-
COI: 1:CAS:528:DC%2BD3sXjvFWlt70%3D, PID: 12765832
-
Novatchkova M, Leibbrandt A, Werzowa J, Neubuser A, Eisenhaber F (2003) The STIR-domain superfamily in signal transduction, development and immunity. Trends Biochem Sci 28:226–229
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 226-229
-
-
Novatchkova, M.1
Leibbrandt, A.2
Werzowa, J.3
Neubuser, A.4
Eisenhaber, F.5
-
64
-
-
65749091607
-
A protective function for interleukin 17A in T cell-mediated intestinal inflammation
-
PID: 19448631
-
O’Connor W Jr, Kamanaka M, Booth CJ, Town T, Nakae S, Iwakura Y, Kolls JK, Flavell RA (2009) A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol 10:603–609
-
(2009)
Nat Immunol
, vol.10
, pp. 603-609
-
-
O’Connor, W.1
Kamanaka, M.2
Booth, C.J.3
Town, T.4
Nakae, S.5
Iwakura, Y.6
Kolls, J.K.7
Flavell, R.A.8
-
65
-
-
58049194071
-
Emergence of the Th17 pathway and its role in host defense
-
PID: 19117534
-
O’Quinn DB, Palmer MT, Lee YK, Weaver CT (2008) Emergence of the Th17 pathway and its role in host defense. Adv Immunol 99:115–163
-
(2008)
Adv Immunol
, vol.99
, pp. 115-163
-
-
O’Quinn, D.B.1
Palmer, M.T.2
Lee, Y.K.3
Weaver, C.T.4
-
66
-
-
84862657675
-
Regulation of epithelial immunity by IL-17 family cytokines
-
COI: 1:CAS:528:DC%2BC38XkvFaju7w%3D, PID: 22476048
-
Pappu R, Rutz S, Ouyang W (2012) Regulation of epithelial immunity by IL-17 family cytokines. Trends Immunol 33:343–349
-
(2012)
Trends Immunol
, vol.33
, pp. 343-349
-
-
Pappu, R.1
Rutz, S.2
Ouyang, W.3
-
67
-
-
0029956024
-
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells
-
COI: 1:CAS:528:DyaK28Xjslait78%3D, PID: 8676088
-
Powrie F, Carlino J, Leach MW, Mauze S, Coffman RL (1996) A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J Exp Med 183:2669–2674
-
(1996)
J Exp Med
, vol.183
, pp. 2669-2674
-
-
Powrie, F.1
Carlino, J.2
Leach, M.W.3
Mauze, S.4
Coffman, R.L.5
-
68
-
-
84954566376
-
The correlations between IL-17 vs. Th17 cells and cancer patient survival: a systematic review
-
PID: 25949881
-
Punt S, Langenhoff JM, Putter H, Fleuren GJ, Gorter A, Jordanova ES (2015) The correlations between IL-17 vs. Th17 cells and cancer patient survival: a systematic review. Oncoimmunology 4:e984547
-
(2015)
Oncoimmunology
, vol.4
-
-
Punt, S.1
Langenhoff, J.M.2
Putter, H.3
Fleuren, G.J.4
Gorter, A.5
Jordanova, E.S.6
-
69
-
-
34247873196
-
The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease
-
COI: 1:CAS:528:DC%2BD2sXhslWmsrc%3D, PID: 17277779
-
Qian Y, Liu C, Hartupee J, Altuntas CZ, Gulen MF, Jane-Wit D, Xiao J, Lu Y, Giltiay N, Liu J, Kordula T, Zhang QW, Vallance B, Swaidani S, Aronica M, Tuohy VK, Hamilton T, Li X (2007) The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. Nat Immunol 8:247–256
-
(2007)
Nat Immunol
, vol.8
, pp. 247-256
-
-
Qian, Y.1
Liu, C.2
Hartupee, J.3
Altuntas, C.Z.4
Gulen, M.F.5
Jane-Wit, D.6
Xiao, J.7
Lu, Y.8
Giltiay, N.9
Liu, J.10
Kordula, T.11
Zhang, Q.W.12
Vallance, B.13
Swaidani, S.14
Aronica, M.15
Tuohy, V.K.16
Hamilton, T.17
Li, X.18
-
70
-
-
84879503193
-
Role of IL-17 in psoriasis and psoriatic arthritis
-
COI: 1:CAS:528:DC%2BC3sXktFeksbg%3D, PID: 22362575
-
Raychaudhuri SP (2013) Role of IL-17 in psoriasis and psoriatic arthritis. Clin Rev Allergy Immunol 44:183–193
-
(2013)
Clin Rev Allergy Immunol
, vol.44
, pp. 183-193
-
-
Raychaudhuri, S.P.1
-
71
-
-
78649699075
-
IL-17 family member cytokines: regulation and function in innate immunity
-
COI: 1:CAS:528:DC%2BC3cXhsFant7rI, PID: 21074482
-
Reynolds JM, Angkasekwinai P, Dong C (2010) IL-17 family member cytokines: regulation and function in innate immunity. Cytokine Growth Factor Rev 21:413–423
-
(2010)
Cytokine Growth Factor Rev
, vol.21
, pp. 413-423
-
-
Reynolds, J.M.1
Angkasekwinai, P.2
Dong, C.3
-
72
-
-
84928210009
-
Interleukin-17B antagonizes interleukin-25-mediated mucosal inflammation
-
COI: 1:CAS:528:DC%2BC2MXmsFSltro%3D, PID: 25888259
-
Reynolds JM, Lee YH, Shi Y, Wang X, Angkasekwinai P, Nallaparaju KC, Flaherty S, Chang SH, Watarai H, Dong C (2015) Interleukin-17B antagonizes interleukin-25-mediated mucosal inflammation. Immunity 42:692–703
-
(2015)
Immunity
, vol.42
, pp. 692-703
-
-
Reynolds, J.M.1
Lee, Y.H.2
Shi, Y.3
Wang, X.4
Angkasekwinai, P.5
Nallaparaju, K.C.6
Flaherty, S.7
Chang, S.H.8
Watarai, H.9
Dong, C.10
-
73
-
-
56149091567
-
Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities
-
COI: 1:CAS:528:DC%2BD1cXhtVKntbnM, PID: 18768888
-
Rickel EA, Siegel LA, Yoon BR, Rottman JB, Kugler DG, Swart DA, Anders PM, Tocker JE, Comeau MR, Budelsky AL (2008) Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J Immunol 181:4299–4310
-
(2008)
J Immunol
, vol.181
, pp. 4299-4310
-
-
Rickel, E.A.1
Siegel, L.A.2
Yoon, B.R.3
Rottman, J.B.4
Kugler, D.G.5
Swart, D.A.6
Anders, P.M.7
Tocker, J.E.8
Comeau, M.R.9
Budelsky, A.L.10
-
74
-
-
79251569587
-
IL-23-mediated psoriasis-like epidermal hyperplasia is dependent on IL-17A
-
COI: 1:CAS:528:DC%2BC3MXnsVOjsw%3D%3D, PID: 21172868
-
Rizzo HL, Kagami S, Phillips KG, Kurtz SE, Jacques SL, Blauvelt A (2011) IL-23-mediated psoriasis-like epidermal hyperplasia is dependent on IL-17A. J Immunol 186:1495–1502
-
(2011)
J Immunol
, vol.186
, pp. 1495-1502
-
-
Rizzo, H.L.1
Kagami, S.2
Phillips, K.G.3
Kurtz, S.E.4
Jacques, S.L.5
Blauvelt, A.6
-
75
-
-
84955729361
-
Secukinumab for treating plaque psoriasis
-
COI: 1:CAS:528:DC%2BC2MXitVWisrbF, PID: 26577956
-
Rothstein B, Gottlieb A (2016) Secukinumab for treating plaque psoriasis. Expert Opin Biol Ther 16:119–128
-
(2016)
Expert Opin Biol Ther
, vol.16
, pp. 119-128
-
-
Rothstein, B.1
Gottlieb, A.2
-
76
-
-
0027215897
-
CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene
-
COI: 1:CAS:528:DyaK3sXmtFylu7c%3D, PID: 8390535
-
Rouvier E, Luciani MF, Mattei MG, Denizot F, Golstein P (1993) CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J Immunol 150:5445–5456
-
(1993)
J Immunol
, vol.150
, pp. 5445-5456
-
-
Rouvier, E.1
Luciani, M.F.2
Mattei, M.G.3
Denizot, F.4
Golstein, P.5
-
77
-
-
1642576088
-
Functional cooperation between interleukin-17 and tumor necrosis factor-alpha is mediated by CCAAT/enhancer-binding protein family members
-
COI: 1:CAS:528:DC%2BD2cXkslOkuw%3D%3D, PID: 14600152
-
Ruddy MJ, Wong GC, Liu XK, Yamamoto H, Kasayama S, Kirkwood KL, Gaffen SL (2004) Functional cooperation between interleukin-17 and tumor necrosis factor-alpha is mediated by CCAAT/enhancer-binding protein family members. J Biol Chem 279:2559–2567
-
(2004)
J Biol Chem
, vol.279
, pp. 2559-2567
-
-
Ruddy, M.J.1
Wong, G.C.2
Liu, X.K.3
Yamamoto, H.4
Kasayama, S.5
Kirkwood, K.L.6
Gaffen, S.L.7
-
78
-
-
77952772125
-
IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction
-
COI: 1:CAS:528:DC%2BC3cXkt1Wqtb0%3D, PID: 20228199
-
Shahrara S, Pickens SR, Mandelin AM 2nd, Karpus WJ, Huang Q, Kolls JK, Pope RM (2010) IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction. J Immunol 184:4479–4487
-
(2010)
J Immunol
, vol.184
, pp. 4479-4487
-
-
Shahrara, S.1
Pickens, S.R.2
Mandelin, A.M.3
Karpus, W.J.4
Huang, Q.5
Kolls, J.K.6
Pope, R.M.7
-
79
-
-
66149138031
-
IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain
-
PID: 19244213
-
Shen F, Li N, Gade P, Kalvakolanu DV, Weibley T, Doble B, Woodgett JR, Wood TD, Gaffen SL (2009) IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain. Sci Signal 2:ra8
-
(2009)
Sci Signal
, vol.2
, pp. ra8
-
-
Shen, F.1
Li, N.2
Gade, P.3
Kalvakolanu, D.V.4
Weibley, T.5
Doble, B.6
Woodgett, J.R.7
Wood, T.D.8
Gaffen, S.L.9
-
80
-
-
84964413447
-
Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases
-
COI: 1:CAS:528:DC%2BC28XhtlWqsLg%3D, PID: 26390837
-
Silacci M, Lembke W, Woods R, Attinger-Toller I, Baenziger-Tobler N, Batey S, Santimaria R, von der Bey U, Koenig-Friedrich S, Zha W, Schlereth B, Locher M, Bertschinger J, Grabulovski D (2016) Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases. MAbs 8:141–149
-
(2016)
MAbs
, vol.8
, pp. 141-149
-
-
Silacci, M.1
Lembke, W.2
Woods, R.3
Attinger-Toller, I.4
Baenziger-Tobler, N.5
Batey, S.6
Santimaria, R.7
von der Bey, U.8
Koenig-Friedrich, S.9
Zha, W.10
Schlereth, B.11
Locher, M.12
Bertschinger, J.13
Grabulovski, D.14
-
81
-
-
84859578124
-
A protective role by interleukin-17F in colon tumorigenesis
-
COI: 1:CAS:528:DC%2BC38XmtVOlsbo%3D, PID: 22509371
-
Tong Z, Yang XO, Yan H, Liu W, Niu X, Shi Y, Fang W, Xiong B, Wan Y, Dong C (2012) A protective role by interleukin-17F in colon tumorigenesis. PLoS One 7:e34959
-
(2012)
PLoS One
, vol.7
-
-
Tong, Z.1
Yang, X.O.2
Yan, H.3
Liu, W.4
Niu, X.5
Shi, Y.6
Fang, W.7
Xiong, B.8
Wan, Y.9
Dong, C.10
-
82
-
-
84969759480
-
A revolutionary therapeutic approach for psoriasis: bispecific biological agents
-
Torres T, Romanelli M, Chiricozzi A (2016) A revolutionary therapeutic approach for psoriasis: bispecific biological agents. Expert Opin Investig Drugs 25(7):1–4
-
(2016)
Expert Opin Investig Drugs
, vol.25
, Issue.7
, pp. 1-4
-
-
Torres, T.1
Romanelli, M.2
Chiricozzi, A.3
-
83
-
-
84929077597
-
Neutralizing IL-23 is superior to blocking IL-17 in suppressing intestinal inflammation in a spontaneous murine colitis model
-
PID: 25803508
-
Wang R, Hasnain SZ, Tong H, Das I, Che-Hao Chen A, Oancea I, Proctor M, Florin TH, Eri RD, McGuckin MA (2015) Neutralizing IL-23 is superior to blocking IL-17 in suppressing intestinal inflammation in a spontaneous murine colitis model. Inflamm Bowel Dis 21:973–984
-
(2015)
Inflamm Bowel Dis
, vol.21
, pp. 973-984
-
-
Wang, R.1
Hasnain, S.Z.2
Tong, H.3
Das, I.4
Che-Hao Chen, A.5
Oancea, I.6
Proctor, M.7
Florin, T.H.8
Eri, R.D.9
McGuckin, M.A.10
-
84
-
-
79955758706
-
Th17 cells in cancer: help or hindrance?
-
COI: 1:CAS:528:DC%2BC3MXlvVygsrY%3D, PID: 21304053
-
Wilke CM, Kryczek I, Wei S, Zhao E, Wu K, Wang G, Zou W (2011) Th17 cells in cancer: help or hindrance? Carcinogenesis 32:643–649
-
(2011)
Carcinogenesis
, vol.32
, pp. 643-649
-
-
Wilke, C.M.1
Kryczek, I.2
Wei, S.3
Zhao, E.4
Wu, K.5
Wang, G.6
Zou, W.7
-
85
-
-
0030587910
-
IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
-
COI: 1:CAS:528:DyaK28Xmtlahtbw%3D, PID: 8871615
-
Willenborg DO, Fordham S, Bernard CC, Cowden WB, Ramshaw IA (1996) IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J Immunol 157:3223–3227
-
(1996)
J Immunol
, vol.157
, pp. 3223-3227
-
-
Willenborg, D.O.1
Fordham, S.2
Bernard, C.C.3
Cowden, W.B.4
Ramshaw, I.A.5
-
86
-
-
80455160171
-
Safety of biologic therapy in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC3MXhtl2gsrnL, PID: 21989284
-
Woodrick RS, Ruderman EM (2011) Safety of biologic therapy in rheumatoid arthritis. Nat Rev Rheumatol 7:639–652
-
(2011)
Nat Rev Rheumatol
, vol.7
, pp. 639-652
-
-
Woodrick, R.S.1
Ruderman, E.M.2
-
87
-
-
34250305962
-
Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells
-
COI: 1:CAS:528:DC%2BD2sXks1Ggtro%3D, PID: 17355969
-
Wright JF, Guo Y, Quazi A, Luxenberg DP, Bennett F, Ross JF, Qiu Y, Whitters MJ, Tomkinson KN, Dunussi-Joannopoulos K, Carreno BM, Collins M, Wolfman NM (2007) Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells. J Biol Chem 282:13447–13455
-
(2007)
J Biol Chem
, vol.282
, pp. 13447-13455
-
-
Wright, J.F.1
Guo, Y.2
Quazi, A.3
Luxenberg, D.P.4
Bennett, F.5
Ross, J.F.6
Qiu, Y.7
Whitters, M.J.8
Tomkinson, K.N.9
Dunussi-Joannopoulos, K.10
Carreno, B.M.11
Collins, M.12
Wolfman, N.M.13
-
88
-
-
69949120571
-
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
-
COI: 1:CAS:528:DC%2BD1MXhtVersbvJ, PID: 19701202
-
Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL (2009) A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 15:1016–1022
-
(2009)
Nat Med
, vol.15
, pp. 1016-1022
-
-
Wu, S.1
Rhee, K.J.2
Albesiano, E.3
Rabizadeh, S.4
Wu, X.5
Yen, H.R.6
Huso, D.L.7
Brancati, F.L.8
Wick, E.9
McAllister, F.10
Housseau, F.11
Pardoll, D.M.12
Sears, C.L.13
-
89
-
-
79959538387
-
Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of ROR gamma t protein
-
COI: 1:CAS:528:DC%2BC3MXnvFektLg%3D, PID: 21566134
-
Xu T, Wang X, Zhong B, Nurieva RI, Ding S, Dong C (2011) Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of ROR gamma t protein. J Biol Chem 286:22707–22710
-
(2011)
J Biol Chem
, vol.286
, pp. 22707-22710
-
-
Xu, T.1
Wang, X.2
Zhong, B.3
Nurieva, R.I.4
Ding, S.5
Dong, C.6
-
90
-
-
43549110961
-
Regulation of inflammatory responses by IL-17F
-
COI: 1:CAS:528:DC%2BD1cXlvFWrsrc%3D, PID: 18411338
-
Yang XO, Chang SH, Park H, Nurieva R, Shah B, Acero L, Wang YH, Schluns KS, Broaddus RR, Zhu Z, Dong C (2008) Regulation of inflammatory responses by IL-17F. J Exp Med 205:1063–1075
-
(2008)
J Exp Med
, vol.205
, pp. 1063-1075
-
-
Yang, X.O.1
Chang, S.H.2
Park, H.3
Nurieva, R.4
Shah, B.5
Acero, L.6
Wang, Y.H.7
Schluns, K.S.8
Broaddus, R.R.9
Zhu, Z.10
Dong, C.11
-
91
-
-
0029555301
-
Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
-
COI: 1:CAS:528:DyaK28XhtF2gsw%3D%3D, PID: 8777726
-
Yao Z, Fanslow WC, Seldin MF, Rousseau AM, Painter SL, Comeau MR, Cohen JI, Spriggs MK (1995) Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3:811–821
-
(1995)
Immunity
, vol.3
, pp. 811-821
-
-
Yao, Z.1
Fanslow, W.C.2
Seldin, M.F.3
Rousseau, A.M.4
Painter, S.L.5
Comeau, M.R.6
Cohen, J.I.7
Spriggs, M.K.8
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