Neutralizing IL-23 is superior to blocking IL-17 in suppressing intestinal inflammation in a spontaneous murine colitis model

Inflammatory Bowel Diseases

Volumn 21, Issue 5, 2015, Pages 973-984

  Wang, Ran ^a   Hasnain, Sumaira Z ^a   Tong, Hui ^a   Das, Indrajit ^a,b   Che Hao Chen, Alice ^a   Oancea, Iulia ^a   Proctor, Martina ^a   Florin, Timothy H ^a   Eri, Rajaraman D ^a,c   McGuckin, Michael A ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b GRIFFITH UNIVERSITY   (Australia)

^c UNIVERSITY OF TASMANIA   (Australia)

Author keywords

colitis; IL 17; IL 23; inflammatory bowel disease

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 23; INTERLEUKIN 23 ANTIBODY; INTERLEUKIN 23P19; MESSENGER RNA; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; CYTOKINE; IL17A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DISEASE COURSE; DISEASE SEVERITY; DOWN REGULATION; EPITHELIUM CELL; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; LEUKOCYTE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL; WEIGHT REDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CD4+ T LYMPHOCYTE; CELL CULTURE; DISEASE MODEL; ENZYME IMMUNOASSAY; FEMALE; GENETICS; IMMUNOLOGY; INFLAMMATION; INTESTINE; KNOCKOUT MOUSE; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; COLITIS; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOENZYME TECHNIQUES; INFLAMMATION; INTERLEUKIN-17; INTERLEUKIN-23; INTESTINES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84929077597     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0000000000000353     Document Type: Article

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