메뉴 건너뛰기




Volumn 111, Issue 15, 2014, Pages 5664-5669

T helper 17 cells play a critical pathogenic role in lung cancer

Author keywords

Interleukin 17; Lung adenocarcinoma

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 22; K RAS PROTEIN; SECRETORY PROTEIN;

EID: 84898777944     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1319051111     Document Type: Article
Times cited : (275)

References (46)
  • 1
    • 84888633713 scopus 로고    scopus 로고
    • Inflammation-induced cancer: Crosstalk between tumours, immune cells and microorganisms
    • Elinav E, et al. (2013) Inflammation-induced cancer: Crosstalk between tumours, immune cells and microorganisms. Nat Rev Cancer 13(11):759-771
    • (2013) Nat Rev Cancer , vol.13 , Issue.11 , pp. 759-771
    • Elinav, E.1
  • 2
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M (2010) Immunity, inflammation, and cancer. Cell 140(6):883-899
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 3
    • 34249670253 scopus 로고    scopus 로고
    • A risk model for prediction of lung cancer
    • Spitz MR, et al. (2007) A risk model for prediction of lung cancer. J Natl Cancer Inst 99(9):715-726
    • (2007) J Natl Cancer Inst , vol.99 , Issue.9 , pp. 715-726
    • Spitz, M.R.1
  • 4
    • 84862616765 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease and lung cancer: Common pathogenesis, shared clinical challenges
    • Celli BR (2012) Chronic obstructive pulmonary disease and lung cancer: Common pathogenesis, shared clinical challenges. Proc Am Thorac Soc 9(2):74-79
    • (2012) Proc Am Thorac Soc , vol.9 , Issue.2 , pp. 74-79
    • Celli, B.R.1
  • 6
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: Impact on clinical outcome
    • Fridman WH, Pages F, Sautes-Fridman C, Galon J (2012) The immune contexture in human tumours: Impact on clinical outcome. Nat Rev Cancer 12(4):298-306
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Sautes-Fridman, C.3    Galon, J.4
  • 7
    • 73649112422 scopus 로고    scopus 로고
    • Tobacco smoke promotes lung tumorigenesis by triggering ikkbeta-And jnk1-dependent inflammation
    • Takahashi H, Ogata H, Nishigaki R, Broide DH, Karin M (2010) Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta-And JNK1-dependent inflammation. Cancer Cell 17(1):89-97
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 89-97
    • Takahashi, H.1    Ogata, H.2    Nishigaki, R.3    Broide, D.H.4    Karin, M.5
  • 8
    • 70449109147 scopus 로고    scopus 로고
    • Requirement for nf-kappab signalling in a mouse model of lung adenocarcinoma
    • Meylan E, et al. (2009) Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma. Nature 462(7269):104-107
    • (2009) Nature , vol.462 , Issue.7269 , pp. 104-107
    • Meylan, E.1
  • 9
    • 27544465354 scopus 로고    scopus 로고
    • A distinct lineage of cd4 t cells regulates tissue inflammation by producing interleukin 17
    • Park H, et al. (2005) A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 6(11):1133-1141
    • (2005) Nat Immunol , vol.6 , Issue.11 , pp. 1133-1141
    • Park, H.1
  • 10
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing cd4+ effector t cells develop via a lineage distinct from the t helper type 1 and 2 lineages
    • Harrington LE, et al. (2005) Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6(11): 1123-1132
    • (2005) Nat Immunol , vol.6 , Issue.11 , pp. 1123-1132
    • Harrington, L.E.1
  • 11
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • Kolls JK, Linden A (2004) Interleukin-17 family members and inflammation. Immunity 21(4):467-476
    • (2004) Immunity , vol.21 , Issue.4 , pp. 467-476
    • Kolls, J.K.1    Linden, A.2
  • 12
    • 69849107597 scopus 로고    scopus 로고
    • Phenotype, distribution, generation, and functional and clinical relevance of th17 cells in the human tumor environments
    • Kryczek I, et al. (2009) Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 114(6):1141-1149
    • (2009) Blood , vol.114 , Issue.6 , pp. 1141-1149
    • Kryczek, I.1
  • 13
    • 84455203145 scopus 로고    scopus 로고
    • A role for t-bet-mediated tumour immune surveillance in anti-il-17a treatment of lung cancer
    • Reppert S, et al. (2011) A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer. Nat Commun 2:600
    • (2011) Nat Commun , vol.2 , pp. 600
    • Reppert, S.1
  • 14
    • 77955095712 scopus 로고    scopus 로고
    • Increased il-17-producing cells correlate with poor survival and lymphangiogenesis in nsclc patients
    • Chen X, et al. (2010) Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients. Lung Cancer 69(3):348-354
    • (2010) Lung Cancer , vol.69 , Issue.3 , pp. 348-354
    • Chen, X.1
  • 15
    • 84857745081 scopus 로고    scopus 로고
    • Human t(h)17 immune cells specific for the tumor antigen mage-A3 convert to ifn-gamma-secreting cells as they differentiate into effector t cells in vivo
    • Hamai A, et al. (2012) Human T(H)17 immune cells specific for the tumor antigen MAGE-A3 convert to IFN-gamma-secreting cells as they differentiate into effector T cells in vivo. Cancer Res 72(5):1059-1063
    • (2012) Cancer Res , vol.72 , Issue.5 , pp. 1059-1063
    • Hamai, A.1
  • 16
    • 67650684023 scopus 로고    scopus 로고
    • The il-17/il-23 axis of inflammation in cancer: Friend or foe?
    • Martin-Orozco N, Dong C (2009) The IL-17/IL-23 axis of inflammation in cancer: Friend or foe? Curr Opin Investig Drugs 10(6):543-549
    • (2009) Curr Opin Investig Drugs , vol.10 , Issue.6 , pp. 543-549
    • Martin-Orozco, N.1    Dong, C.2
  • 17
    • 77950420796 scopus 로고    scopus 로고
    • Ablation of il-17a abrogates progression of spontaneous intestinal tumorigenesis
    • Chae WJ, et al. (2010) Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis. Proc Natl Acad Sci USA 107(12):5540-5544
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.12 , pp. 5540-5544
    • Chae, W.J.1
  • 18
    • 69949120571 scopus 로고    scopus 로고
    • A human colonic commensal promotes colon tumorigenesis via activation of t helper type 17 t cell responses
    • Wu S, et al. (2009) A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 15(9):1016-1022
    • (2009) Nat Med , vol.15 , Issue.9 , pp. 1016-1022
    • Wu, S.1
  • 19
    • 84868613705 scopus 로고    scopus 로고
    • Adenoma-linked barrier defects and microbial products drive il-23/il-17-mediated tumour growth
    • Grivennikov SI, et al. (2012) Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 491(7423):254-258
    • (2012) Nature , vol.491 , Issue.7423 , pp. 254-258
    • Grivennikov, S.I.1
  • 20
    • 84859578124 scopus 로고    scopus 로고
    • A protective role by interleukin-17f in colon tumorigenesis
    • Tong Z, et al. (2012) A protective role by interleukin-17F in colon tumorigenesis. PLoS ONE 7(4):e34959
    • (2012) PLoS ONE , vol.7 , Issue.4
    • Tong, Z.1
  • 21
    • 67651094058 scopus 로고    scopus 로고
    • Endogenous il-17 contributes to reduced tumor growth and metastasis
    • Kryczek I, Wei S, Szeliga W, Vatan L, Zou W (2009) Endogenous IL-17 contributes to reduced tumor growth and metastasis. Blood 114(2):357-359
    • (2009) Blood , vol.114 , Issue.2 , pp. 357-359
    • Kryczek, I.1    Wei, S.2    Szeliga, W.3    Vatan, L.4    Zou, W.5
  • 22
    • 67650495415 scopus 로고    scopus 로고
    • Il-17 can promote tumor growth through an il-6-stat3 signaling pathway
    • Wang L, et al. (2009) IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 206(7):1457-1464
    • (2009) J Exp Med , vol.206 , Issue.7 , pp. 1457-1464
    • Wang, L.1
  • 23
    • 70449530422 scopus 로고    scopus 로고
    • T helper 17 cells promote cytotoxic t cell activation in tumor immunity
    • Martin-Orozco N, et al. (2009) T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 31(5):787-798
    • (2009) Immunity , vol.31 , Issue.5 , pp. 787-798
    • Martin-Orozco, N.1
  • 24
    • 47649122633 scopus 로고    scopus 로고
    • Tumor-specific th17-polarized cells eradicate large established melanoma
    • Muranski P, et al. (2008) Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood 112(2):362-373
    • (2008) Blood , vol.112 , Issue.2 , pp. 362-373
    • Muranski, P.1
  • 25
    • 63349088232 scopus 로고    scopus 로고
    • Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a k-ras-induced mouse model
    • Moghaddam SJ, et al. (2009) Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model. Am J Respir Cell Mol Biol 40(4):443-453
    • (2009) Am J Respir Cell Mol Biol , vol.40 , Issue.4 , pp. 443-453
    • Moghaddam, S.J.1
  • 26
    • 0035893252 scopus 로고    scopus 로고
    • Analysis of lung tumor initiation and progression using conditional expression of oncogenic k-ras
    • Jackson EL, et al. (2001) Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev 15(24):3243-3248
    • (2001) Genes Dev , vol.15 , Issue.24 , pp. 3243-3248
    • Jackson, E.L.1
  • 27
    • 47549116834 scopus 로고    scopus 로고
    • Cre-mediated recombination in mouse clara cells
    • Li H, et al. (2008) Cre-mediated recombination in mouse Clara cells. Genesis 46(6): 300-307
    • (2008) Genesis , vol.46 , Issue.6 , pp. 300-307
    • Li, H.1
  • 28
    • 33645518095 scopus 로고    scopus 로고
    • K-ras activation generates an inflammatory response in lung tumors
    • Ji H, et al. (2006) K-ras activation generates an inflammatory response in lung tumors. Oncogene 25(14):2105-2112
    • (2006) Oncogene , vol.25 , Issue.14 , pp. 2105-2112
    • Ji, H.1
  • 29
    • 0035662726 scopus 로고    scopus 로고
    • Nontypeable haemophilus influenzae in the lower respiratory tract of patients with chronic bronchitis
    • Bandi V, et al. (2001) Nontypeable Haemophilus influenzae in the lower respiratory tract of patients with chronic bronchitis. Am J Respir Crit Care Med 164(11):2114-2119
    • (2001) Am J Respir Crit Care Med , vol.164 , Issue.11 , pp. 2114-2119
    • Bandi, V.1
  • 30
    • 78149330949 scopus 로고    scopus 로고
    • Hif-1alpha regulates function and differentiation of myeloidderived suppressor cells in the tumor microenvironment
    • Corzo CA, et al. (2010) HIF-1alpha regulates function and differentiation of myeloidderived suppressor cells in the tumor microenvironment. J Exp Med 207(11):2439-2453
    • (2010) J Exp Med , vol.207 , Issue.11 , pp. 2439-2453
    • Corzo, C.A.1
  • 32
    • 84861135108 scopus 로고    scopus 로고
    • Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse models
    • Zhang Q, et al. (2012) Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse models. Cancer Res 72(10):2589-2599
    • (2012) Cancer Res , vol.72 , Issue.10 , pp. 2589-2599
    • Zhang, Q.1
  • 33
    • 84883826749 scopus 로고    scopus 로고
    • Il-17 mediates resistance to anti-vegf therapy
    • Maniati E, Hagemann T (2013) IL-17 mediates resistance to anti-VEGF therapy. Nat Med 19(9):1092-1094
    • (2013) Nat Med , vol.19 , Issue.9 , pp. 1092-1094
    • Maniati, E.1    Hagemann, T.2
  • 34
    • 84879401216 scopus 로고    scopus 로고
    • Expression of rorgammat marks a pathogenic regulatory t cell subset in human colon cancer
    • Blatner NR, et al. (2012) Expression of RORgammat marks a pathogenic regulatory T cell subset in human colon cancer. Sci Transl Med 4(164):ra159
    • (2012) Sci Transl Med , vol.4 , Issue.164
    • Blatner, N.R.1
  • 35
    • 0037085768 scopus 로고    scopus 로고
    • Interleukin-17 inhibits tumor cell growth by means of a t-cell-dependent mechanism
    • Benchetrit F, et al. (2002) Interleukin-17 inhibits tumor cell growth by means of a T-cell-dependent mechanism. Blood 99(6):2114-2121
    • (2002) Blood , vol.99 , Issue.6 , pp. 2114-2121
    • Benchetrit, F.1
  • 36
    • 84863625224 scopus 로고    scopus 로고
    • A cxcl1 paracrine network links cancer chemoresistance and metastasis
    • Acharyya S, et al. (2012) A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell 150(1):165-178
    • (2012) Cell , vol.150 , Issue.1 , pp. 165-178
    • Acharyya, S.1
  • 37
    • 33646255924 scopus 로고    scopus 로고
    • High expression of ligands for chemokine receptor cxcr2 in alveolar epithelial neoplasia induced by oncogenic kras
    • Wislez M, et al. (2006) High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras. Cancer Res 66(8):4198-4207
    • (2006) Cancer Res , vol.66 , Issue.8 , pp. 4198-4207
    • Wislez, M.1
  • 38
    • 84862147254 scopus 로고    scopus 로고
    • Oncogenic krasinduced gm-csf production promotes the development of pancreatic neoplasia
    • Pylayeva-Gupta Y, Lee KE, Hajdu CH, Miller G, Bar-Sagi D (2012) Oncogenic Krasinduced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell 21(6):836-847
    • (2012) Cancer Cell , vol.21 , Issue.6 , pp. 836-847
    • Pylayeva-Gupta, Y.1    Lee, K.E.2    Hajdu, C.H.3    Miller, G.4    Bar-Sagi, D.5
  • 39
    • 84862150896 scopus 로고    scopus 로고
    • Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and t cell immunity in pancreatic cancer
    • Bayne LJ, et al. (2012) Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer. Cancer Cell 21(6):822-835
    • (2012) Cancer Cell , vol.21 , Issue.6 , pp. 822-835
    • Bayne, L.J.1
  • 40
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • Murdoch C, Muthana M, Coffelt SB, Lewis CE (2008) The role of myeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer 8(8):618-631
    • (2008) Nat Rev Cancer , vol.8 , Issue.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 41
    • 84889840938 scopus 로고    scopus 로고
    • Promoting effect of neutrophils on lung tumorigenesis is mediated by cxcr2 and neutrophil elastase
    • Gong L, et al. (2013) Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase. Mol Cancer 12(1):154
    • (2013) Mol Cancer , vol.12 , Issue.1 , pp. 154
    • Gong, L.1
  • 42
    • 77954664861 scopus 로고    scopus 로고
    • Lung myeloid dendritic cells coordinately induce th1 and th17 responses in human emphysema
    • Shan M, et al. (2009) Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema. Sci Transl Med 1(4):ra10
    • (2009) Sci Transl Med , vol.1 , Issue.4
    • Shan, M.1
  • 43
    • 84856068597 scopus 로고    scopus 로고
    • Cigarette smoke induction of osteopontin (spp1) mediates t(h)17 inflammation in human and experimental emphysema
    • Shan M, et al. (2012) Cigarette smoke induction of osteopontin (SPP1) mediates T(H)17 inflammation in human and experimental emphysema. Sci Transl Med 4(117):ra119
    • (2012) Sci Transl Med , vol.4 , Issue.117
    • Shan, M.1
  • 44
    • 79957613753 scopus 로고    scopus 로고
    • Il-17ra is required for ccl2 expression, macrophage recruitment, and emphysema in response to cigarette smoke
    • Chen K, et al. (2011) IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke. PLoS ONE 6(5):e20333
    • (2011) PLoS ONE , vol.6 , Issue.5
    • Chen, K.1
  • 45
    • 84860321700 scopus 로고    scopus 로고
    • Oncogenic kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
    • Ying H, et al. (2012) Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell 149(3):656-670
    • (2012) Cell , vol.149 , Issue.3 , pp. 656-670
    • Ying, H.1
  • 46
    • 43549110961 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by il-17f
    • Yang XXO, et al. (2008) Regulation of inflammatory responses by IL-17F. J Exp Med 205(5):1063-1075.
    • (2008) J Exp Med , vol.205 , Issue.5 , pp. 1063-1075
    • Yang, X.X.O.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.