Vitamin C alleviates aging defects in a stem cell model for Werner syndrome

Protein and Cell

Volumn 7, Issue 7, 2016, Pages 478-488

  Li, Ying ^a,b   Zhang, Weizhou ^e   Chang, Liang ^d   Han, Yan ^a,b   Sun, Liang ^f   Gong, Xiaojun ⁱ   Tang, Hong ⁱ   Liu, Zunpeng ^a,b   Deng, Huichao ^a,b   Ye, Yanxia ^c   Wang, Yu ^c   Li, Jian ^f   Qiao, Jie ^d   Qu, Jing ^b,c   Zhang, Weiqi ^a,g   Liu, Guang Hui ^a,b,g,h  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c INSTITUTE OF ZOOLOGY   (China)

^d PEKING UNIVERSITY THIRD HOSPITAL   (China)

^e UNIVERSITY OF IOWA   (United States)

^f BEIJING HOSPITAL   (China)

^g FOSHAN UNIVERSITY   (China)

^h BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

ⁱ CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

aging; stem cell; Vitamin C; Werner syndrome

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ASCORBIC ACID; EPIGALLOCATECHIN GALLATE; METFORMIN; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; RESVERATROL; HETEROCHROMATIN;

ARTICLE; CELL CYCLE REGULATION; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; DRUG SCREENING; HETEROCHROMATIN; HUMAN; HUMAN CELL; INFLAMMATION; MESENCHYMAL STEM CELL; NUCLEAR LAMINA; PREMATURE AGING; PRIORITY JOURNAL; RNA SEQUENCE; SENESCENCE; TELOMERE SHORTENING; WERNER SYNDROME; ANIMAL; CELL AGING; CELL CYCLE CHECKPOINT; CELL LINE; DISEASE MODEL; DNA DAMAGE; DRUG EFFECTS; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; MOUSE; PATHOLOGY; TELOMERE HOMEOSTASIS;

ANIMALS; ASCORBIC ACID; CELL AGING; CELL CYCLE CHECKPOINTS; CELL LINE; DISEASE MODELS, ANIMAL; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; HETEROCHROMATIN; HUMANS; MESENCHYMAL STROMAL CELLS; MICE; NUCLEAR LAMINA; REACTIVE OXYGEN SPECIES; TELOMERE HOMEOSTASIS; WERNER SYNDROME;

EID: 84983073946     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-016-0278-1     Document Type: Article

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