Vitamin C requirement in surgical patients

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 13, Issue 6, 2010, Pages 669-676

  Fukushima, Ryoji ^a   Yamazaki, Eriko ^a  

^a TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ascorbate; ascorbic acid; surgery; vitamin C

Indexed keywords

ASCORBIC ACID;

CRITICALLY ILL PATIENT; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG MEGADOSE; FOOD AND DRUG ADMINISTRATION; GASTROINTESTINAL SURGERY; HEART ATRIUM FIBRILLATION; HEART SURGERY; HUMAN; INTENSIVE CARE UNIT; MAXILLOFACIAL SURGERY; NONHUMAN; NUTRITIONAL REQUIREMENT; OXIDATIVE STRESS; REVIEW; SURGICAL PATIENT; URINARY EXCRETION; VITAMIN INTAKE; VITAMIN SUPPLEMENTATION; WOUND HEALING;

ASCORBIC ACID; ASCORBIC ACID DEFICIENCY; CRITICAL ILLNESS; DIETARY SUPPLEMENTS; HUMANS; NUTRITION POLICY; OXIDATIVE STRESS; PARENTERAL NUTRITION; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATIONS;

EID: 78149285213     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0b013e32833e05bc     Document Type: Review

References (56)

1. Berger MM. Vitamin C requirements in parenteral nutrition. Gastroenterology • 2009;137:S70-S78. This is a latest review on vitamin C in parenteral nutrition.
2. Lukaski HC. Vitamin and mineral status: effects on physical performance. Nutrition 2004;20:632-644.
3. Shenkin A. Basics in clinical nutrition: physiological function and deficiency states of vitamins. e-SPEN 2008;3: e275-e280.
4. Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-1423.
5. US Department of Health and Human Services and US Department of Agriculture (2005). Food Sources of Vitamin C. In: Dietary Guidelines for Americans, 2005. 6th Edition, Washington, DC: US Government Printing Office. p. 65.
6. Graumlich JF, Ludden TM, Conry-Cantilena C, et al. Pharmacokinetic model of ascorbic acid in healthy male volunteers during depletion and repletion. Pharm Res 1997;14:1133-1139.
7. Levine M, Conry-Cantilena C, Wang Y, et al. Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. Proc Natl Acad Sci U S A 1996;93:3704-3709.
8. Fukuwatari T, Shibata K. Urinary water-soluble vitamins and their metabolite contents as nutritional markers for evaluating vitamin intakes in young Japanese women. J Nutr Sci Vitaminol 2008;54:223-229.
9. National Academy of Sciences (2000). Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D. C.: National Academy Press. pp. 1-20.
10. Padayatty SJ, Sun H, Wang Y, et al. Vitamin C pharmacokinetics: implications for oral and intravenous use. Ann Intern Med 2004;140:533-537.
11. Guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients. JPEN J Parenter Enteral Nutr 2002;26:1SA-138SA.
12. Braga M, Ljungqvist O, Soeters P, et al. ESPEN guidelines on parenteral nutrition: surgery. Clin Nutr 2009;28:378-386.
13. Johnston CS, Steinberg FM, Rucker RB. Ascorbic acid. Handbook of vitamins. 3rd ed. New York: Marcel Dekker, Inc; 2001. pp. 529-554.
14. Fukushima R, Koide T, Yamazaki E, et al. Water-soluble-vitamin status in the postoperative gastrointestinal surgical patients receiving peripheral parenteral nutrition. Clin Nutr 2009;4:164.
15. McGinn FP, Hamilton JC. Ascorbic acid levels in stored blood and in patients undergoing surgery after blood transfusion. Br J Surg 1976;63:505-507.
16. Louw JA, Werbeck A, Louw ME, et al. Blood vitamin concentrations during the acute-phase response. Crit Care Med 1992;20:934-941.
17. Long CL, Maull KI, Krishnan RS, et al. Ascorbic acid dynamics in the seriously ill and injured. J Surg Res 2003;109:144-148.
18. Baines M, Shenkin A. Lack of effectiveness of short-term intravenous micronutrient nutrition in restoring plasma antioxidant status after surgery. Clin Nutr 2002;21:145-150.
19. Rock CL, Dechert RE, Khilnani R, et al. Carotenoids and antioxidant vitamins in patients after burn injury. J Burn Care Rehabil 1997;18:269-278; discussion 268.
20. Sriram K, Lonchyna VA. Micronutrient supplementation in adult nutrition therapy: practical considerations. JPEN J Parenter Enteral Nutr 2009;33:548-562.
21. Borrelli E, Roux-Lombard P, Grau GE, et al. Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk. Crit Care Med 1996;24:392-397.
22. Rumelin A, Humbert T, Luhker O, et al. Metabolic clearance of the antioxidant ascorbic acid in surgical patients. J Surg Res 2005;129:46-51.
23. Blee TH, Cogbill TH, Lambert PJ. Hemorrhage associated with vitamin C deficiency in surgical patients. Surgery 2002;131:408-412.
24. Perret JL, Lagauche D, Favier JC, et al. Scurvy in intensive care despite vitamin supplementation. Presse Med 2004;33:170-171.
25. Yamazaki E, Horikawa M, Fukushima R. Vitamin C supplementation in patients •• receiving peripheral parenteral nutrition after gastrointestinal surgery. Nutrition 2010 [Epub ahead of print]. This study demonstrated that in uncomplicated gastrointestinal surgical patients, 500 mg/day, but not 100 mg/day of continuous infusion of vitamin C maintained blood concentration.
26. Luo M, Fernandez-Estivariz C, Jones DP, et al. Depletion of plasma antioxidants in surgical intensive care unit patients requiring parenteral feeding: effects of parenteral nutrition with or without alanyl-glutamine dipeptide supplementation. Nutrition 2008;24:37-44.
27. Rumelin A, Jaehde U, Kerz T, et al. Early postoperative substitution procedure of the antioxidant ascorbic acid. J Nutr Biochem 2005;16:104-108.
28. Rodrigo R, Vinay J, Castillo R, et al. Use of vitamins C and E as a prophylactic therapy to prevent postoperative atrial fibrillation. Int J Cardiol 2010;138:221-228.
29. Carnes CA, Chung MK, Nakayama T, et al. Ascorbate attenuates atrial pacinginduced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation. Circ Res 2001;89:E32-38.
30. Eslami M, Badkoubeh RS, Mousavi M, et al. Oral ascorbic acid in combination with beta-blockers is more effective than beta-blockers alone in the prevention of atrial fibrillation after coronary artery bypass grafting. Tex Heart Inst J 2007;34:268-274.
31. Ellinger S, Stehle P. Efficacy of vitamin supplementation in situations with • wound healing disorders: results from clinical intervention studies. Curr Opin Clin Nutr Metab Care 2009;12:588-595. This is a review article on vitamin supplementation in wound healing disorders. Although this review primarily focused on the healing of pressure ulcer, some on surgical wound healing were also discussed.
32. Vaxman F, Chalkiadakis G, Olender S, et al. Improvement in the healing of colonic anastomoses by vitamin B5 and C supplements: experimental study in the rabbit. Ann Chir 1990;44:512-520.
33. Petroianu A, Souza SD, Martins SG, Alberti LR. Influence of ascorbic acid on anastomosis and in jejunal loop in rat. Arq Gastroenterol 2001;38:48-52.
34. Cevikel MH, Tuncyurek P, Ceylan F, et al. Supplementation with high-dose ascorbic acid improves intestinal anastomotic healing. Eur Surg Res 2008;40:29-33.
35. Petroianu A, Alberti LR, Souza SD, Martins SG. Effect of ascorbic acid and hidrocortisone on intestinal anastomotic tension. Rev Col Bras Cir 2009;36:509-513.
36. Schorah CJ, Downing C, Piripitsi A, et al. Total vitamin C, ascorbic acid, and dehydroascorbic acid concentrations in plasma of critically ill patients. Am J Clin Nutr 1996;63:760-765.
37. Ferron-Celma I, Mansilla A, Hassan L, et al. Effect of vitamin C administration on neutrophil apoptosis in septic patients after abdominal surgery. J Surg Res 2009;153:224-230.
38. McGregor GP, Biesalski HK. Rationale and impact of vitamin C in clinical nutrition. Curr Opin Clin Nutr Metab Care 2006;9:697-703.
39. Tyml K, Li F, Wilson JX. Delayed ascorbate bolus protects against maldistribution of microvascular blood flow in septic rat skeletal muscle. Crit Care Med 2005;33:1823-1828.
40. Wilson JX. Mechanism of action of vitamin C in sepsis: ascorbate modulates redox signaling in endothelium. Biofactors 2009;35:5-13.
41. Biesalski HK, McGregor GP. Antioxidant therapy in critical care: is the microcirculation the primary target? Crit Care Med 2007;35:S577-583.
42. Nathens AB, Neff MJ, Jurkovich GJ, et al. Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg 2002;236:814-822.
43. Berger MM, Soguel L, Shenkin A, et al. Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients. Crit Care 2008;12:R101.
44. Collier BR, Giladi A, Dossett LA, et al. Impact of high-dose antioxidants on outcomes in acutely injured patients. JPEN J Parenter Enteral Nutr 2008;32:384-388.
45. Giladi AM, Dossett LA, Fleming SB, et al. High-dose antioxidant administration is associated with a reduction in postinjury complications in critically ill trauma patients. Injury 2010;41:857-861.
46. Kremer T, Harenberg P, Hernekamp F, et al. High-dose vitamin C treatment reduces capillary leakage after burn plasma transfer in rats. J Burn Care Res 2010;31:470-479.
47. Dubick MA, Williams C, Elgjo GI, Kramer GC. High-dose vitamin C infusion reduces fluid requirements in the resuscitation of burn-injured sheep. Shock 2005;24:139-144.
48. Tanaka H, Matsuda T, Miyagantani Y, et al. Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study. Arch Surg 2000;135:326-331.
49. Barbosa E, Faintuch J, Machado Moreira EA, et al. Supplementation of vitamin • E, vitamin C, and zinc attenuates oxidative stress in burned children: a randomized, double-blind, placebo-controlled pilot study. J Burn Care Res 2009;30:859-866. This prospective randomized pilot study investigated the effect of supplementation of vitamin E, vitamin C, and zinc on the oxidative stress in 32 burned children. The antioxidant supplementation enhanced antioxidant protection against oxidative stress and allowed less time for wound healing.
50. Robitaille L, Mamer OA, Miller WH Jr, et al. Oxalic acid excretion after intravenous ascorbic acid administration. Metabolism 2009;58:263-269.
51. Wong K, Thomson C, Bailey RR, et al. Acute oxalate nephropathy after a massive intravenous dose of vitamin C. Aust N Z J Med 1994;24:410-411.
52. Mashour S, Turner JF Jr, Merrell R. Acute renal failure, oxalosis, and vitamin C supplementation: a case report and review of the literature. Chest 2000;118:561-563.
53. Alkhunaizi AM, Chan L. Secondary oxalosis: a cause of delayed recovery of renal function in the setting of acute renal failure. J Am Soc Nephrol 1996;7:2320-2326.
54. Lee SH, Yoon YC, Jang YY, et al. Effect of iron and ascorbate on cyclosporineinduced oxidative damage of kidney mitochondria and microsomes. Pharmacol Res 2001;43:161-171.
55. Carr A, Frei B. Does vitamin C act as a pro-oxidant under physiological conditions? FASEB J 1999;13:1007-1024.
56. Muhlhofer A, Mrosek S, Schlegel B, et al. High-dose intravenous vitamin C is not associated with an increase of pro-oxidative biomarkers. Eur J Clin Nutr 2004;58:1151-1158.