-
1
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3: 730-7.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
2
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. PNAS U S A 2003; 100: 3983-8.
-
(2003)
PNAS U S A
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
3
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature 2004; 432: 396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
4
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C, De Maria R. Identification and expansion of human colon-cancer-initiating cells. Nature 2007; 445: 111-5.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
De Maria, R.7
-
5
-
-
39449088496
-
Identification and expansion of the tumorigenic lung cancer stem cell population
-
Eramo A, Lotti F, Sette G, et al. Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ 2008; 15: 504-14.
-
(2008)
Cell Death Differ
, vol.15
, pp. 504-514
-
-
Eramo, A.1
Lotti, F.2
Sette, G.3
-
6
-
-
49249091523
-
Identification and characterization of ovarian cancer-initiating cells from primary human tumors
-
Zhang S, Balch C, Chan MW, et al. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res 2008; 68: 4311-20.
-
(2008)
Cancer Res
, vol.68
, pp. 4311-4320
-
-
Zhang, S.1
Balch, C.2
Chan, M.W.3
-
7
-
-
78449281896
-
Tumorigenic and metastatic activity of human thyroid cancer stem cells
-
Todaro M, Iovino F, Eterno V, et al. Tumorigenic and metastatic activity of human thyroid cancer stem cells. Cancer Res 2010; 70: 8874-85.
-
(2010)
Cancer Res
, vol.70
, pp. 8874-8885
-
-
Todaro, M.1
Iovino, F.2
Eterno, V.3
-
8
-
-
33847740988
-
Wnt/beta-catenin signaling in cancer stemness and malignant behavior
-
Fodde R, Brabletz T. Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol 2007; 19: 150-8.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 150-158
-
-
Fodde, R.1
Brabletz, T.2
-
9
-
-
77951975325
-
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
-
Vermeulen L, De Sousa E Melo F, van der Heijden M, et al. Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat Cell Biol 2010; 12: 468-76.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 468-476
-
-
Vermeulen, L.1
De Sousa, E.2
Melo, F.3
Van Der Heijden, M.4
-
10
-
-
35348837163
-
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma
-
Bar EE, Chaudhry A, Lin A, et al. Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Stem Cells 2007; 25: 2524-33.
-
(2007)
Stem Cells
, vol.25
, pp. 2524-2533
-
-
Bar, E.E.1
Chaudhry, A.2
Lin, A.3
-
11
-
-
84867116494
-
Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway
-
Ramaswamy B, Lu Y, Teng KY, Nuovo G, Li X, Shapiro CL, Majumder S. Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway. Cancer Res 2012; 72: 5048-59.
-
(2012)
Cancer Res
, vol.72
, pp. 5048-5059
-
-
Ramaswamy, B.1
Lu, Y.2
Teng, K.Y.3
Nuovo, G.4
Li, X.5
Shapiro, C.L.6
Majumder, S.7
-
12
-
-
84873185664
-
Stem cells living with a Notch
-
Koch U, Lehal R, Radtke F. Stem cells living with a Notch. Development 2013; 140: 689-704.
-
(2013)
Development
, vol.140
, pp. 689-704
-
-
Koch, U.1
Lehal, R.2
Radtke, F.3
-
13
-
-
79960668961
-
Notch1 inhibition alters the CD44hi/ CD24lo population and reduces the formation of brain metastases from breast cancer
-
McGowan PM, Simedrea C, Ribot EJ, Foster PJ, Palmieri D, Steeg PS, Allan AL, Chambers AF. Notch1 inhibition alters the CD44hi/ CD24lo population and reduces the formation of brain metastases from breast cancer. Mol Cancer Res 2011; 9: 834-44.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 834-844
-
-
McGowan, P.M.1
Simedrea, C.2
Ribot, E.J.3
Foster, P.J.4
Palmieri, D.5
Steeg, P.S.6
Allan, A.L.7
Chambers, A.F.8
-
14
-
-
70350757395
-
Bone morphogenetic proteins in development and progression of breast cancer and therapeutic potential (review)
-
Ye L, Bokobza SM, Jiang WG. Bone morphogenetic proteins in development and progression of breast cancer and therapeutic potential (review). Int J Mol Med 2009; 24: 591-7.
-
(2009)
Int J Mol Med
, vol.24
, pp. 591-597
-
-
Ye, L.1
Bokobza, S.M.2
Jiang, W.G.3
-
15
-
-
84867530190
-
TGF beta signaling and its role in glioma pathogenesis
-
Kaminska B, Kocyk M, Kijewska M. TGF beta signaling and its role in glioma pathogenesis. Adv Exp Med Biol 2013; 986: 171-87.
-
(2013)
Adv Exp Med Biol
, vol.986
, pp. 171-187
-
-
Kaminska, B.1
Kocyk, M.2
Kijewska, M.3
-
16
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-15.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
-
17
-
-
84860314217
-
The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation
-
Buijs JT, van der Horst G, van den Hoogen C, et al. The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation. Oncogene 2012; 31: 2164-74.
-
(2012)
Oncogene
, vol.31
, pp. 2164-2174
-
-
Buijs, J.T.1
Van Der Horst, G.2
Van Den Hoogen, C.3
-
18
-
-
46149083522
-
Targeting signaling pathways with small molecules to treat autoimmune disorders
-
Kaminska B, Swiatek-Machado K. Targeting signaling pathways with small molecules to treat autoimmune disorders. Expert Rev Clin Immunol 2008; 4: 93-112.
-
(2008)
Expert Rev Clin Immunol
, vol.4
, pp. 93-112
-
-
Kaminska, B.1
Swiatek-Machado, K.2
-
19
-
-
79959956046
-
The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24-stem celllike breast cancer cells in human tumors
-
Marotta LL, Almendro V, Marusyk A, et al. The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24-stem celllike breast cancer cells in human tumors. J Clin Invest 2011; 121: 2723-35.
-
(2011)
J Clin Invest
, vol.121
, pp. 2723-2735
-
-
Marotta, L.L.1
Almendro, V.2
Marusyk, A.3
-
20
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006; 441: 431-6.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
21
-
-
35648970074
-
IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells
-
Cao Y, Luo JL, Karin M. IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells. PNAS U S A 2007; 104: 15852-7.
-
(2007)
PNAS U S A
, vol.104
, pp. 15852-15857
-
-
Cao, Y.1
Luo, J.L.2
Karin, M.3
-
23
-
-
84869880156
-
Epigenetic alterations involved in cancer stem cell reprogramming
-
Muñoz P, Iliou MS, Esteller M. Epigenetic alterations involved in cancer stem cell reprogramming. Mol Oncol 2012; 6: 620-36.
-
(2012)
Mol Oncol
, vol.6
, pp. 620-636
-
-
Muñoz, P.1
Iliou, M.S.2
Esteller, M.3
-
24
-
-
0038349957
-
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
-
Park IK, Qian D, Kiel M, Becker MW, Pihalja M, Weissman IL, Morrison SJ, Clarke MF. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003; 423: 302-5.
-
(2003)
Nature
, vol.423
, pp. 302-305
-
-
Park, I.K.1
Qian, D.2
Kiel, M.3
Becker, M.W.4
Pihalja, M.5
Weissman, I.L.6
Morrison, S.J.7
Clarke, M.F.8
-
25
-
-
33746459740
-
Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors
-
Pardal R, Molofsky AV, He S, Morrison SJ. Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors. Cold Spring Harb Symp Quant Biol 2005; 70: 177-85.
-
(2005)
Cold Spring Harb Symp Quant Biol
, vol.70
, pp. 177-185
-
-
Pardal, R.1
Molofsky, A.V.2
He, S.3
Morrison, S.J.4
-
26
-
-
84857497457
-
Role of BMI1, a stem cell factor, in cancer recurrence and chemoresistance: Preclinical and clinical evidences
-
Siddique HR, Saleem M. Role of BMI1, a stem cell factor, in cancer recurrence and chemoresistance: preclinical and clinical evidences. Stem Cells 2012; 30: 372-8.
-
(2012)
Stem Cells
, vol.30
, pp. 372-378
-
-
Siddique, H.R.1
Saleem, M.2
-
27
-
-
77956178360
-
EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
-
Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 2010; 29: 4741-51.
-
(2010)
Oncogene
, vol.29
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
-
28
-
-
84860389952
-
Epithelial-mesenchymal transition and cancer stem cells: A dangerously dynamic duo in breast cancer progression
-
May CD, Sphyris N, Evans KW, Werden SJ, Guo W, Mani SA. Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression. Breast Cancer Res 2011; 13: 202.
-
(2011)
Breast Cancer Res
, vol.13
, pp. 202
-
-
May, C.D.1
Sphyris, N.2
Evans, K.W.3
Werden, S.J.4
Guo, W.5
Mani, S.A.6
-
29
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-76.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
30
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 1-12.
-
(2007)
Cell
, vol.131
, pp. 1-12
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
31
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, Weinberg RA. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008; 40: 499-507.
-
(2008)
Nat Genet
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
Weinberg, R.A.7
-
32
-
-
84858341630
-
Sox2 expression in breast tumours and activation in breast cancer stem cells
-
Leis O, Eguiara A, Lopez-Arribillaga E, et al. Sox2 expression in breast tumours and activation in breast cancer stem cells. Oncogene 2012; 31: 1354-65.
-
(2012)
Oncogene
, vol.31
, pp. 1354-1365
-
-
Leis, O.1
Eguiara, A.2
Lopez-Arribillaga, E.3
-
33
-
-
84861343721
-
Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas
-
Basu-Roy U, Seo E, Ramanathapuram L, Rapp TB, Perry JA, Orkin SH, Mansukhani A, Basilico C. Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas. Oncogene 2012; 31: 2270-82.
-
(2012)
Oncogene
, vol.31
, pp. 2270-2282
-
-
Basu-Roy, U.1
Seo, E.2
Ramanathapuram, L.3
Rapp, T.B.4
Perry, J.A.5
Orkin, S.H.6
Mansukhani, A.7
Basilico, C.8
-
34
-
-
84884163527
-
Targeting cancer stem cells: Emerging role of Nanog transcription factor
-
Wang ML, Chiou SH, Wu CW. Targeting cancer stem cells: emerging role of Nanog transcription factor. Onco Targets Ther 2013; 4: 1207-20.
-
(2013)
Onco Targets Ther
, vol.4
, pp. 1207-1220
-
-
Wang, M.L.1
Chiou, S.H.2
Wu, C.W.3
-
35
-
-
67651005780
-
Expression of an exogenous human Oct-4 promoter identifies tumor-initiating cells in osteosarcoma
-
Levings PP, McGarry SV, Currie TP, Nickerson DM, McClellan S, Ghivizzani SC, Steindler DA, Gibbs CP. Expression of an exogenous human Oct-4 promoter identifies tumor-initiating cells in osteosarcoma. Cancer Res 2009; 69: 5648-55.
-
(2009)
Cancer Res
, vol.69
, pp. 5648-5655
-
-
Levings, P.P.1
McGarry, S.V.2
Currie, T.P.3
Nickerson, D.M.4
McClellan, S.5
Ghivizzani, S.C.6
Steindler, D.A.7
Gibbs, C.P.8
-
36
-
-
84864922025
-
Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer
-
Stolzenburg S, Rots MG, Beltran AS, Rivenbark AG, Yuan X, Qian H, Strahl BD, Blancafort P. Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer. Nucleic Acids Res 2012; 40: 6725-40.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 6725-6740
-
-
Stolzenburg, S.1
Rots, M.G.2
Beltran, A.S.3
Rivenbark, A.G.4
Yuan, X.5
Qian, H.6
Strahl, B.D.7
Blancafort, P.8
-
37
-
-
84901190709
-
The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis
-
Lu X, Mazur SJ, Lin T, Appella E, Xu Y. The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis. Oncogene 2014; 33: 2655-2664.
-
(2014)
Oncogene
, vol.33
, pp. 2655-2664
-
-
Lu, X.1
Mazur, S.J.2
Lin, T.3
Appella, E.4
Xu, Y.5
-
38
-
-
84873741701
-
Embryonic stem cells markers SOX2, OCT4 and Nanog expression and their correlations with epithelial-mesenchymal transition in nasopharyngeal carcinoma
-
Luo W, Li S, Peng B, Ye Y, Deng X, Yao K. Embryonic stem cells markers SOX2, OCT4 and Nanog expression and their correlations with epithelial-mesenchymal transition in nasopharyngeal carcinoma. PLoS One 2013; 8: e56324.
-
(2013)
PLoS One
, vol.8
, pp. e56324
-
-
Luo, W.1
Li, S.2
Peng, B.3
Ye, Y.4
Deng, X.5
Yao, K.6
-
39
-
-
84883358002
-
Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines
-
Wang XQ, Ng RK, Ming X, et al. Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines. PLoS One 2013; 8: e72435.
-
(2013)
PLoS One
, vol.8
, pp. e72435
-
-
Wang, X.Q.1
Ng, R.K.2
Ming, X.3
-
40
-
-
84860561774
-
Epigenetic reprogramming of cancer cells via targeted DNA methylation
-
Rivenbark AG, Stolzenburg S, Beltran AS, Yuan X, Rots MG, Strahl BD, Blancafort P. Epigenetic reprogramming of cancer cells via targeted DNA methylation. Epigenetics 2012; 7: 350-60.
-
(2012)
Epigenetics
, vol.7
, pp. 350-360
-
-
Rivenbark, A.G.1
Stolzenburg, S.2
Beltran, A.S.3
Yuan, X.4
Rots, M.G.5
Strahl, B.D.6
Blancafort, P.7
-
41
-
-
84856518779
-
Distinct patterns of promoter CpG island methylation of breast cancer subtypes are associated with stem cell phenotypes
-
Park SY, Kwon HJ, Choi Y, et al. Distinct patterns of promoter CpG island methylation of breast cancer subtypes are associated with stem cell phenotypes. Mod Pathol 2012; 25: 185-96.
-
(2012)
Mod Pathol
, vol.25
, pp. 185-196
-
-
Park, S.Y.1
Kwon, H.J.2
Choi, Y.3
-
42
-
-
48649099908
-
Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer
-
Nagel R, Le Sage C, Diosdado B, van der Waal M, Oude Vrielink JA, Bolijn A, Meijer GA, Agami R. Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer Res 2008; 68: 5795-802.
-
(2008)
Cancer Res
, Issue.68
, pp. 5795-5802
-
-
Nagel, R.1
Le Sage, C.2
Diosdado, B.3
Van Der Waal, M.4
Oude Vrielink, J.A.5
Bolijn, A.6
Meijer, G.A.7
Agami, R.8
-
43
-
-
78449255989
-
MiR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling
-
Xia H, Cheung WK, Sze J, et al. miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling. J Biol Chem 2010; 285: 36995-7004.
-
(2010)
J Biol Chem
, vol.285
, pp. 36995-37004
-
-
Xia, H.1
Cheung, W.K.2
Sze, J.3
-
44
-
-
84901471917
-
Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties
-
Taube JH, Malouf GG, Lu E, et al. Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties. Sci Rep 2013; 3: 2687-96.
-
(2013)
Sci Rep
, vol.3
, pp. 2687-2696
-
-
Taube, J.H.1
Malouf, G.G.2
Lu, E.3
-
45
-
-
84866040307
-
MiR-214 targets b-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma
-
Xia H, Ooi LL, Hui KM. MiR-214 targets b-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma. PLoS One 2012; 7: e44206.
-
(2012)
PLoS One
, vol.7
, pp. e44206
-
-
Xia, H.1
Ooi, L.L.2
Hui, K.M.3
-
46
-
-
84855360862
-
MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer
-
Hirata H, Hinoda Y, Ueno K, Shahryari V, Tabatabai ZL, Dahiya R. MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer. Carcinogenesis 2012; 33: 41-8.
-
(2012)
Carcinogenesis
, vol.33
, pp. 41-48
-
-
Hirata, H.1
Hinoda, Y.2
Ueno, K.3
Shahryari, V.4
Tabatabai, Z.L.5
Dahiya, R.6
-
47
-
-
84857979406
-
MicroRNA-1826 directly targets beta-catenin (CTNNB1) and MEK1 (MAP2K1) in VHL-inactivated renal cancer
-
Hirata H, Hinoda Y, Ueno K, Nakajima K, Ishii N, Dahiya R. MicroRNA-1826 directly targets beta-catenin (CTNNB1) and MEK1 (MAP2K1) in VHL-inactivated renal cancer. Carcinogenesis 2012; 33: 501-8.
-
(2012)
Carcinogenesis
, vol.33
, pp. 501-508
-
-
Hirata, H.1
Hinoda, Y.2
Ueno, K.3
Nakajima, K.4
Ishii, N.5
Dahiya, R.6
-
48
-
-
84874782801
-
MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway
-
Hsieh IS, Chang KC, Tsai YT, et al. MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway. Carcinogenesis 2013; 34: 530-8.
-
(2013)
Carcinogenesis
, vol.34
, pp. 530-538
-
-
Hsieh, I.S.1
Chang, K.C.2
Tsai, Y.T.3
-
49
-
-
84859812754
-
MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting b-catenin
-
Sun JY, Huang Y, Li JP, et al. MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting b-catenin. Biochem Biophys Res Commun 2012; 420: 787-92.
-
(2012)
Biochem Biophys Res Commun
, vol.420
, pp. 787-792
-
-
Sun, J.Y.1
Huang, Y.2
Li, J.P.3
-
50
-
-
55549114664
-
The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
-
Bonci D, Coppola V, Musumeci M, et al. The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med 2008; 14: 1271-7.
-
(2008)
Nat Med
, vol.14
, pp. 1271-1277
-
-
Bonci, D.1
Coppola, V.2
Musumeci, M.3
-
51
-
-
79957912993
-
EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis
-
Cheng AS, Lau SS, Chen Y, et al. EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis. Cancer Res 2011; 71: 4028-39.
-
(2011)
Cancer Res
, vol.71
, pp. 4028-4039
-
-
Cheng, A.S.1
Lau, S.S.2
Chen, Y.3
-
52
-
-
47149097853
-
Epigenetic gene silencing in the Wnt pathway in breast cancer
-
Klarmann GJ, Decker A, Farrar WL. Epigenetic gene silencing in the Wnt pathway in breast cancer. Epigenetics 2008; 3: 59-63.
-
(2008)
Epigenetics
, vol.3
, pp. 59-63
-
-
Klarmann, G.J.1
Decker, A.2
Farrar, W.L.3
-
53
-
-
33745634864
-
Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer
-
Ai L, Tao Q, Zhong S, et al. Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Carcinogenesis 2006; 27: 1341-8.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1341-1348
-
-
Ai, L.1
Tao, Q.2
Zhong, S.3
-
54
-
-
68349139365
-
Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer
-
Veeck J, Wild PJ, Fuchs T, Schüffler PJ, Hartmann A, Knüchel R, Dahl E. Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer. BMC Cancer 2009; 9: 217-30.
-
(2009)
BMC Cancer
, vol.9
, pp. 217-230
-
-
Veeck, J.1
Wild, P.J.2
Fuchs, T.3
Schüffler, P.J.4
Hartmann, A.5
Knüchel, R.6
Dahl, E.7
-
55
-
-
65949116604
-
Tobacco smoke induces polycomb-mediated repression of Dickkopf-1 in lung cancer cells
-
Hussain M, Rao M, Humphries AE, Hong JA, Liu F, Yang M, Caragacianu D, Schrump DS. Tobacco smoke induces polycomb-mediated repression of Dickkopf-1 in lung cancer cells. Cancer Res 2009; 69: 3570-8.
-
(2009)
Cancer Res
, vol.69
, pp. 3570-3578
-
-
Hussain, M.1
Rao, M.2
Humphries, A.E.3
Hong, J.A.4
Liu, F.5
Yang, M.6
Caragacianu, D.7
Schrump, D.S.8
-
56
-
-
84862330054
-
Beta-Catenin/ LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/beta-catenin-signaling pathway
-
Zhou AD, Diao LT, Xu H, Xiao ZD, Li JH, Zhou H, Qu LH. beta-Catenin/ LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/beta-catenin-signaling pathway. Oncogene 2012; 31: 2968-78.
-
(2012)
Oncogene
, vol.31
, pp. 2968-2978
-
-
Zhou, A.D.1
Diao, L.T.2
Xu, H.3
Xiao, Z.D.4
Li, J.H.5
Zhou, H.6
Qu, L.H.7
-
57
-
-
84888341007
-
Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/b-catenin signalling and apoptosis regulation in breast cancer cells
-
Xiang T, Li L, Yin X, Zhong L, Peng W, Qiu Z, Ren G, Tao Q. Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/b-catenin signalling and apoptosis regulation in breast cancer cells. J Cell Mol Med 2013; 17: 1236-46.
-
(2013)
J Cell Mol Med
, vol.17
, pp. 1236-1246
-
-
Xiang, T.1
Li, L.2
Yin, X.3
Zhong, L.4
Peng, W.5
Qiu, Z.6
Ren, G.7
Tao, Q.8
-
58
-
-
84876411649
-
DACT1, an antagonist to Wnt/b-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer
-
Yin X, Xiang T, Li L, et al. DACT1, an antagonist to Wnt/b-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer. Breast Cancer Res 2013; 15: R23.
-
(2013)
Breast Cancer Res
, vol.15
, pp. R23
-
-
Yin, X.1
Xiang, T.2
Li, L.3
-
59
-
-
44449134715
-
DACT3 is an epigenetic regulator of Wnt/ beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications
-
Jiang X, Tan J, Li J, et al. DACT3 is an epigenetic regulator of Wnt/ beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. Cancer Cell 2008; 13: 529-41.
-
(2008)
Cancer Cell
, vol.13
, pp. 529-541
-
-
Jiang, X.1
Tan, J.2
Li, J.3
-
60
-
-
53949090314
-
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
-
Ji Q, Hao X, Meng Y, Zhang M, Desano J, Fan D, Xu L. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer 2008; 8: 266-78.
-
(2008)
BMC Cancer
, vol.8
, pp. 266-278
-
-
Ji, Q.1
Hao, X.2
Meng, Y.3
Zhang, M.4
Desano, J.5
Fan, D.6
Xu, L.7
-
61
-
-
84855279252
-
MicroRNA 34c gene down-regulation via DNA methylation promotes self-renewal and epithelial-mesenchymal transition in breast tumor-initiating cells
-
Yu F, Jiao Y, Zhu Y, et al. MicroRNA 34c gene down-regulation via DNA methylation promotes self-renewal and epithelial-mesenchymal transition in breast tumor-initiating cells. J Biol Chem 2012; 287: 465-73.
-
(2012)
J Biol Chem
, vol.287
, pp. 465-473
-
-
Yu, F.1
Jiao, Y.2
Zhu, Y.3
-
62
-
-
79951810835
-
Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells
-
Vallejo DM, Caparros E, Dominguez M. Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells. EMBO J 2011; 30: 756-69.
-
(2011)
EMBO J
, vol.30
, pp. 756-769
-
-
Vallejo, D.M.1
Caparros, E.2
Dominguez, M.3
-
63
-
-
70350221952
-
MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes
-
Li Y, Guessous F, Zhang Y, et al. MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res 2009; 69: 7569-76.
-
(2009)
Cancer Res
, vol.69
, pp. 7569-7576
-
-
Li, Y.1
Guessous, F.2
Zhang, Y.3
-
64
-
-
77953920780
-
MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells
-
Pang RT, Leung CO, Ye TM, Liu W, Chiu PC, Lam KK, Lee KF, Yeung WS. MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells. Carcinogenesis 2010; 31: 1037-44.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1037-1044
-
-
Pang, R.T.1
Leung, C.O.2
Ye, T.M.3
Liu, W.4
Chiu, P.C.5
Lam, K.K.6
Lee, K.F.7
Yeung, W.S.8
-
65
-
-
66249085579
-
Loss of the SMRT/ NCoR2 corepressor correlates with JAG2 overexpression in multiple myeloma
-
Ghoshal P, Nganga AJ, Moran-Giuati J, et al. Loss of the SMRT/ NCoR2 corepressor correlates with JAG2 overexpression in multiple myeloma. Cancer Res 2009; 69: 4380-7.
-
(2009)
Cancer Res
, vol.69
, pp. 4380-4387
-
-
Ghoshal, P.1
Nganga, A.J.2
Moran-Giuati, J.3
-
66
-
-
57149092998
-
Cyclic stretch induced miR-146a upregulation delays C2C12 myogenic differentiation through inhibition of Numb
-
Kuang W, Tan J, Duan Y. Cyclic stretch induced miR-146a upregulation delays C2C12 myogenic differentiation through inhibition of Numb. Biochem Biophys Res Commun 2009; 378: 259-63.
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 259-263
-
-
Kuang, W.1
Tan, J.2
Duan, Y.3
-
67
-
-
53549129980
-
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells
-
Ferretti E, De Smaele E, Miele E, et al. Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells. EMBO J 2008; 27: 2616-27.
-
(2008)
EMBO J
, vol.27
, pp. 2616-2627
-
-
Ferretti, E.1
De Smaele, E.2
Miele, E.3
-
68
-
-
54249158400
-
Emerging role of miR-106b-25/ miR-17-92 clusters in the control of transforming growth factor beta signaling
-
Petrocca F, Vecchione A, Croce CM. Emerging role of miR-106b-25/ miR-17-92 clusters in the control of transforming growth factor beta signaling. Cancer Res 2008; 68: 8191-4.
-
(2008)
Cancer Res
, vol.68
, pp. 8191-8194
-
-
Petrocca, F.1
Vecchione, A.2
Croce, C.M.3
-
69
-
-
68049114782
-
Down-regulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Shimono Y, Zabala M, Cho RW, et al. Down-regulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 2009; 138: 592-603.
-
(2009)
Cell
, vol.138
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
-
70
-
-
78651454089
-
EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-beta-catenin signaling
-
Chang CJ, Yang JY, Xia W, et al. EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-beta-catenin signaling. Cancer Cell 2011; 19: 86-100.
-
(2011)
Cancer Cell
, vol.19
, pp. 86-100
-
-
Chang, C.J.1
Yang, J.Y.2
Xia, W.3
-
71
-
-
34548434716
-
Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells
-
Pan G, Tian S, Nie J, Yang C, Ruotti V, Wei H, Jonsdottir GA, Stewart R, Thomson JA. Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 2007; 1: 299-312.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 299-312
-
-
Pan, G.1
Tian, S.2
Nie, J.3
Yang, C.4
Ruotti, V.5
Wei, H.6
Jonsdottir, G.A.7
Stewart, R.8
Thomson, J.A.9
-
72
-
-
84874324849
-
MiR-7 suppresses brain metastasis of breast cancer stem-like cells by modulating KLF4
-
Okuda H, Xing F, Pandey PR, et al. miR-7 suppresses brain metastasis of breast cancer stem-like cells by modulating KLF4. Cancer Res 2013; 73: 1434-44.
-
(2013)
Cancer Res
, vol.73
, pp. 1434-1444
-
-
Okuda, H.1
Xing, F.2
Pandey, P.R.3
-
73
-
-
79955616730
-
Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells
-
Villasante A, Piazzolla D, Li H, Gomez-Lopez G, Djabali M, Serrano M. Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells. Cell Cycle 2011; 10: 1488-98.
-
(2011)
Cell Cycle
, vol.10
, pp. 1488-1498
-
-
Villasante, A.1
Piazzolla, D.2
Li, H.3
Gomez-Lopez, G.4
Djabali, M.5
Serrano, M.6
-
74
-
-
0036848385
-
Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells
-
Koizume S, Tachibana K, Sekiya T, Hirohashi S, Shiraishi M. Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells. Nucleic Acids Res 2002; 30: 4770-80.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 4770-4780
-
-
Koizume, S.1
Tachibana, K.2
Sekiya, T.3
Hirohashi, S.4
Shiraishi, M.5
-
75
-
-
47949125993
-
Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor
-
Herranz N, Pasini D, Díaz VM, et al. Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol Cell Biol 2008; 28: 4772-81.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4772-4781
-
-
Herranz, N.1
Pasini, D.2
Díaz, V.M.3
-
76
-
-
57649124289
-
Repression of E-cadherin by the polycomb group protein EZH2 in cancer
-
Cao Q, Yu J, Dhanasekaran SM, et al. Repression of E-cadherin by the polycomb group protein EZH2 in cancer. Oncogene 2008; 27: 7274-84.
-
(2008)
Oncogene
, vol.27
, pp. 7274-7284
-
-
Cao, Q.1
Yu, J.2
Dhanasekaran, S.M.3
-
77
-
-
0346363757
-
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
-
Peinado H, Ballestar E, Esteller M, Cano A. Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol 2004; 24: 306-19.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 306-319
-
-
Peinado, H.1
Ballestar, E.2
Esteller, M.3
Cano, A.4
-
78
-
-
79957613439
-
MiR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1
-
Hwang-Verslues WW, Chang PH, Wei PC, et al. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. Oncogene 2011; 30: 2463-74.
-
(2011)
Oncogene
, vol.30
, pp. 2463-2474
-
-
Hwang-Verslues, W.W.1
Chang, P.H.2
Wei, P.C.3
-
79
-
-
77956338683
-
Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition
-
Lin T, Ponn A, Hu X, Law BK, Lu J. Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition. Oncogene 2010; 29: 4896-904.
-
(2010)
Oncogene
, vol.29
, pp. 4896-4904
-
-
Lin, T.1
Ponn, A.2
Hu, X.3
Law, B.K.4
Lu, J.5
-
80
-
-
84883154469
-
LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer
-
Ding J, Zhang ZM, Xia Y, Liao GQ, Pan Y, Liu S, Zhang Y, Yan ZS. LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer. Br J Cancer 2013; 109: 994-1003.
-
(2013)
Br J Cancer
, vol.109
, pp. 994-1003
-
-
Ding, J.1
Zhang, Z.M.2
Xia, Y.3
Liao, G.Q.4
Pan, Y.5
Liu, S.6
Zhang, Y.7
Yan, Z.S.8
-
81
-
-
84855340668
-
SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities
-
Yang F, Sun L, Li Q, Han X, Lei L, Zhang H, Shang Y. SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities. EMBO J 2012; 31: 110-23.
-
(2012)
EMBO J
, vol.31
, pp. 110-123
-
-
Yang, F.1
Sun, L.2
Li, Q.3
Han, X.4
Lei, L.5
Zhang, H.6
Shang, Y.7
-
82
-
-
41649091906
-
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
-
Park SM, Gaur AB, Lengyel E, Peter ME. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 2008; 22: 894-907.
-
(2008)
Genes Dev
, vol.22
, pp. 894-907
-
-
Park, S.M.1
Gaur, A.B.2
Lengyel, E.3
Peter, M.E.4
-
83
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Gregory PA, Bert AG, Paterson EL, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10: 593-601.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
-
84
-
-
54049084380
-
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
-
Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, Goodall GJ. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 2008; 68: 7846-54.
-
(2008)
Cancer Res
, vol.68
, pp. 7846-7854
-
-
Bracken, C.P.1
Gregory, P.A.2
Kolesnikoff, N.3
Bert, A.G.4
Wang, J.5
Shannon, M.F.6
Goodall, G.J.7
-
85
-
-
77956243561
-
Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells
-
Neves R, Scheel C, Weinhold S, et al. Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells. BMC Res Notes 2010; 3: 219.
-
(2010)
BMC Res Notes
, vol.3
, pp. 219
-
-
Neves, R.1
Scheel, C.2
Weinhold, S.3
-
86
-
-
49549086856
-
Epigenetic alterations of CDH1 and APC genes: Relationship with activation of Wnt/beta-catenin pathway in invasive ductal carcinoma of breast
-
Prasad CP, Mirza S, Sharma G, Prashad R, DattaGupta S, Rath G, Ralhan R. Epigenetic alterations of CDH1 and APC genes: relationship with activation of Wnt/beta-catenin pathway in invasive ductal carcinoma of breast. Life Sci 2008; 83: 318-25.
-
(2008)
Life Sci
, vol.83
, pp. 318-325
-
-
Prasad, C.P.1
Mirza, S.2
Sharma, G.3
Prashad, R.4
DattaGupta, S.5
Rath, G.6
Ralhan, R.7
-
87
-
-
84863570072
-
Hypermethylated in cancer 1 (HIC1), a tumour suppressor gene epigenetically deregulated in hyperparathyroid tumours by histone H3 lysine modification
-
Svedlund J, Koskinen Edblom S, Marquez VE, Akerström G, Björklund P, Westin G. Hypermethylated in cancer 1 (HIC1), a tumour suppressor gene epigenetically deregulated in hyperparathyroid tumours by histone H3 lysine modification. J Clin Endocrinol Metab 2012; 97: E1307-15.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. E1307-E1315
-
-
Svedlund, J.1
Koskinen Edblom, S.2
Marquez, V.E.3
Akerström, G.4
Björklund, P.5
Westin, G.6
-
88
-
-
84055184566
-
Emerging evidence for MicroRNAs as regulators of cancer stem cells
-
Sethi A, Sholl LM. Emerging Evidence for MicroRNAs as Regulators of Cancer Stem Cells. Cancers (Basel) 2011; 3: 3957-71.
-
(2011)
Cancers (Basel)
, vol.3
, pp. 3957-3971
-
-
Sethi, A.1
Sholl, L.M.2
-
90
-
-
67849124654
-
DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency
-
Hoey T, Yen WC, Axelrod F, et al. DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Cell Stem Cell 2009; 5: 168-77.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 168-177
-
-
Hoey, T.1
Yen, W.C.2
Axelrod, F.3
-
91
-
-
77951884078
-
Cross-talk between miRNA and Notch signaling pathways in tumor development and progression
-
Wang Z, Li Y, Kong D, Ahmad A, Banerjee S, Sarkar FH. Cross-talk between miRNA and Notch signaling pathways in tumor development and progression. Cancer Lett 2010; 292: 141-8.
-
(2010)
Cancer Lett
, vol.292
, pp. 141-148
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Ahmad, A.4
Banerjee, S.5
Sarkar, F.H.6
-
92
-
-
84896963083
-
Krüppel-like factor 8 promotes tumorigenic mammary stem cell induction by targeting miR-146a
-
Wang X, Lu H, Li T, Yu L, Liu G, Peng X, Zhao J. Krüppel-like factor 8 promotes tumorigenic mammary stem cell induction by targeting miR-146a. Am J Cancer Res 2013; 3: 356-73.
-
(2013)
Am J Cancer Res
, vol.3
, pp. 356-373
-
-
Wang, X.1
Lu, H.2
Li, T.3
Yu, L.4
Liu, G.5
Peng, X.6
Zhao, J.7
-
93
-
-
84896894869
-
EZH2 expands breast stem cells through activation of NOTCH1 signaling
-
Gonzalez ME, Moore HM, Li X, Toy KA, Huang W, Sabel MS, Kidwell KM, Kleer CG. EZH2 expands breast stem cells through activation of NOTCH1 signaling. PNAS U S A 2014; 111: 3098-103.
-
(2014)
PNAS U S A
, vol.111
, pp. 3098-3103
-
-
Gonzalez, M.E.1
Moore, H.M.2
Li, X.3
Toy, K.A.4
Huang, W.5
Sabel, M.S.6
Kidwell, K.M.7
Kleer, C.G.8
-
94
-
-
84880570961
-
MicroRNA-antagonism regulates breast cancer stemness and metastasis via tet-family-dependent chromatin remodeling
-
Song SJ, Poliseno L, Song MS, et al. MicroRNA-antagonism regulates breast cancer stemness and metastasis via tet-family-dependent chromatin remodeling. Cell 2013; 154: 311-24.
-
(2013)
Cell
, vol.154
, pp. 311-324
-
-
Song, S.J.1
Poliseno, L.2
Song, M.S.3
-
95
-
-
0346363757
-
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
-
Peinado H, Ballestar E, Esteller M, Cano A. Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol 2004; 24: 306-19.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 306-319
-
-
Peinado, H.1
Ballestar, E.2
Esteller, M.3
Cano, A.4
-
96
-
-
33846783284
-
A proximal activator of transcription in epithelial-mesenchymal transition
-
Venkov CD, Link AJ, Jennings JL, et al. A proximal activator of transcription in epithelial-mesenchymal transition. J Clin Invest 2007; 117: 482-91.
-
(2007)
J Clin Invest
, vol.117
, pp. 482-491
-
-
Venkov, C.D.1
Link, A.J.2
Jennings, J.L.3
-
97
-
-
80053610850
-
Transcriptional networks in epithelial-mesenchymal transition
-
Venkov CD, Plieth D, Ni T, Karmaker A, Bian A, George AL Jr, Neilson EG. Transcriptional networks in epithelial-mesenchymal transition. PLoS One 2011; 6: e25354.
-
(2011)
PLoS One
, vol.6
, pp. e25354
-
-
Venkov, C.D.1
Plieth, D.2
Ni, T.3
Karmaker, A.4
Bian, A.5
George, A.L.6
Neilson, E.G.7
-
98
-
-
33846819015
-
Transcriptional regulation of epithelial-mesenchymal transition
-
Teng Y, Zeisberg M, Kalluri R. Transcriptional regulation of epithelial-mesenchymal transition. J Clin Invest 2007; 117: 304-6.
-
(2007)
J Clin Invest
, vol.117
, pp. 304-306
-
-
Teng, Y.1
Zeisberg, M.2
Kalluri, R.3
-
100
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002; 2: 48-58.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
101
-
-
0026555717
-
Modulation of activity of the promoter of the human MDR1 gene by Ras and p53
-
Chin KV, Ueda K, Pastan I, Gottesman MM. Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. Science 1992; 255: 459-62.
-
(1992)
Science
, vol.255
, pp. 459-462
-
-
Chin, K.V.1
Ueda, K.2
Pastan, I.3
Gottesman, M.M.4
-
102
-
-
35348854570
-
Physical and functional interactions between liver X receptor/retinoid X receptor and Sp1 modulate the transcriptional induction of the human ATP binding cassette transporter A1 gene by oxysterols and retinoids
-
Thymiakou E, Zannis VI, Kardassis D. Physical and functional interactions between liver X receptor/retinoid X receptor and Sp1 modulate the transcriptional induction of the human ATP binding cassette transporter A1 gene by oxysterols and retinoids. Biochemistry 2007; 46: 11473-83.
-
(2007)
Biochemistry
, vol.46
, pp. 11473-11483
-
-
Thymiakou, E.1
Zannis, V.I.2
Kardassis, D.3
-
103
-
-
1042265197
-
Regulation of ATP-binding cassette transporter A1 transcription by thyroid hormone receptor
-
Huuskonen J, Vishnu M, Pullinger CR, Fielding PE, Fielding CJ. Regulation of ATP-binding cassette transporter A1 transcription by thyroid hormone receptor. Biochemistry 2004; 43: 1626-32.
-
(2004)
Biochemistry
, vol.43
, pp. 1626-1632
-
-
Huuskonen, J.1
Vishnu, M.2
Pullinger, C.R.3
Fielding, P.E.4
Fielding, C.J.5
-
104
-
-
84857974889
-
Breast cancer resistance protein (BCRP/ ABCG2): Its role in multidrug resistance and regulation of its gene expression
-
Nakanishi T, Ross DD. Breast cancer resistance protein (BCRP/ ABCG2): its role in multidrug resistance and regulation of its gene expression. Chin J Cancer 2012; 31: 73-99.
-
(2012)
Chin J Cancer
, vol.31
, pp. 73-99
-
-
Nakanishi, T.1
Ross, D.D.2
-
105
-
-
49149114863
-
Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
-
Zhu H, Wu H, Liu X, Evans BR, Medina DJ, Liu CG, Yang JM. Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol 2008; 76: 582-8.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 582-588
-
-
Zhu, H.1
Wu, H.2
Liu, X.3
Evans, B.R.4
Medina, D.J.5
Liu, C.G.6
Yang, J.M.7
-
106
-
-
84884575302
-
MiR-27a modulates the MDR1/P-glycoprotein expression by inhibiting FZD7/b-catenin pathway in hepatocellular carcinoma cells
-
Chen Z, Ma T, Huang C, Zhang L, Lv X, Xu T, Hu T, Li J. MiR-27a modulates the MDR1/P-glycoprotein expression by inhibiting FZD7/b-catenin pathway in hepatocellular carcinoma cells. Cell Signal 2013; 25: 2693-701.
-
(2013)
Cell Signal
, vol.25
, pp. 2693-2701
-
-
Chen, Z.1
Ma, T.2
Huang, C.3
Zhang, L.4
Lv, X.5
Xu, T.6
Hu, T.7
Li, J.8
-
107
-
-
79955025420
-
The role of human aldehyde dehydrogenase in normal and cancer stem cells
-
Ma I, Allan AL. The role of human aldehyde dehydrogenase in normal and cancer stem cells. Stem Cell Rev 2011; 7: 292-306.
-
(2011)
Stem Cell Rev
, vol.7
, pp. 292-306
-
-
Ma, I.1
Allan, A.L.2
-
108
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C, Hur MH, Charafe-Jauffret E, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007; 1: 555-67.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
-
109
-
-
84930474801
-
Aldehyde dehydrogenase inhibitors: A comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application
-
Koppaka V, Thompson DC, Chen Y, et al. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacol Rev 2012; 64: 520-39.
-
(2012)
Pharmacol Rev
, vol.64
, pp. 520-539
-
-
Koppaka, V.1
Thompson, D.C.2
Chen, Y.3
-
110
-
-
15444350522
-
Phase I/II trial of all-trans retinoic acid and tamoxifen in patients with advanced breast cancer
-
Budd GT, Adamson PC, Gupta M, et al. Phase I/II trial of all-trans retinoic acid and tamoxifen in patients with advanced breast cancer. Clin Cancer Res 1998; 4: 635-42.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 635-642
-
-
Budd, G.T.1
Adamson, P.C.2
Gupta, M.3
-
111
-
-
84872773175
-
Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide
-
Triscott J, Lee C, Hu K, et al. Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide. Oncotarget 2012; 3: 1112-23.
-
(2012)
Oncotarget
, vol.3
, pp. 1112-1123
-
-
Triscott, J.1
Lee, C.2
Hu, K.3
-
113
-
-
44049100934
-
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
-
Li X, Lewis MT, Huang J, et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 2008; 100: 672-9.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 672-679
-
-
Li, X.1
Lewis, M.T.2
Huang, J.3
-
114
-
-
44849143103
-
Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors
-
Shafee N, Smith CR, Wei S, Kim Y, Mills GB, Hortobagyi GN, Stanbridge EJ, Lee EY. Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors. Cancer Res 2008; 68: 3243-50.
-
(2008)
Cancer Res
, vol.68
, pp. 3243-3250
-
-
Shafee, N.1
Smith, C.R.2
Wei, S.3
Kim, Y.4
Mills, G.B.5
Hortobagyi, G.N.6
Stanbridge, E.J.7
Lee, E.Y.8
-
115
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn M, Cho RW, Lobo NA, et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009; 458: 780-3.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
|