Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide

Oncotarget

Volumn 3, Issue 10, 2012, Pages 1112-1123

  Triscott, Joanna ^a   Lee, Cathy ^a   Hu, Kaiji ^a   Fotovati, Abbas ^a   Berns, Rachel ^a   Pambid, Mary ^a   Luk, Margaret ^b   Kast, Richard E ^c   Toyota, Eric ^d   Yip, Stephen ^d   Toyot, Brian ^d   Dunn, Sandra E ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VANCOUVER GENERAL HOSPITAL   (Canada)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^d BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

Brain tumor; Disulfiram; Drug resistance; Glioblastoma; Temozolomide

Indexed keywords

4 (8 CYCLOPENTYL 7 ETHYL 5,6,7,8 TETRAHYDRO 5 METHYL 6 OXO 2 PTERIDINYLAMINO) 3 METHOXY N (1 METHYL 4 PIPERIDINYL)BENZAMIDE; DISULFIRAM; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; POLO LIKE KINASE 1; SMALL INTERFERING RNA; TEMOZOLOMIDE; VOLASERTIB;

ALCOHOLISM; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASTROCYTE; CANCER CELL; CANCER INHIBITION; CANCER RESISTANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SENSITIVITY; ENZYME INHIBITION; GLIOBLASTOMA; HUMAN; HUMAN CELL; PRIMARY CELL CULTURE; PROTEIN EXPRESSION;

EID: 84872773175     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.604     Document Type: Article

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