-
1
-
-
39449096135
-
Genome instability: a mechanistic view of its causes and consequences
-
Aguilera A., Gomez-Gonzalez B. Genome instability: a mechanistic view of its causes and consequences. Nat. Rev. Genet. 2008, 9:204-217.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 204-217
-
-
Aguilera, A.1
Gomez-Gonzalez, B.2
-
2
-
-
5444256238
-
Self-renewal and solid tumor stem cells
-
Al-Hajj M., Clarke M.F. Self-renewal and solid tumor stem cells. Oncogene 2004, 23:7274-7282.
-
(2004)
Oncogene
, vol.23
, pp. 7274-7282
-
-
Al-Hajj, M.1
Clarke, M.F.2
-
3
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M., Wicha M.S., Benito-Hernandez A., Morrison S.J., Clarke M.F. Prospective identification of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. USA 2003, 100:3983-3988.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
4
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S., Wu Q., McLendon R.E., Hao Y., Shi Q., Hjelmeland A.B., Dewhirst M.W., Bigner D.D., Rich J.N. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006, 444:756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
5
-
-
34047112221
-
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia
-
Bindra R.S., Glazer P.M. Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia. Oncogene 2007, 26:2048-2057.
-
(2007)
Oncogene
, vol.26
, pp. 2048-2057
-
-
Bindra, R.S.1
Glazer, P.M.2
-
6
-
-
4544324453
-
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells
-
Bindra R.S., Schaffer P.J., Meng A., Woo J., Maseide K., Roth M.E., Lizardi P., Hedley D.W., Bristow R.G., Glazer P.M. Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells. Mol. Cell. Biol. 2004, 24:8504-8518.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8504-8518
-
-
Bindra, R.S.1
Schaffer, P.J.2
Meng, A.3
Woo, J.4
Maseide, K.5
Roth, M.E.6
Lizardi, P.7
Hedley, D.W.8
Bristow, R.G.9
Glazer, P.M.10
-
8
-
-
33947134834
-
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
-
Bracken A.P., Kleine-Kohlbrecher D., Dietrich N., Pasini D., Gargiulo G., Beekman C., Theilgaard-Monch K., Minucci S., Porse B.T., Marine J.C., et al. The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Genes Dev. 2007, 21:525-530.
-
(2007)
Genes Dev.
, vol.21
, pp. 525-530
-
-
Bracken, A.P.1
Kleine-Kohlbrecher, D.2
Dietrich, N.3
Pasini, D.4
Gargiulo, G.5
Beekman, C.6
Theilgaard-Monch, K.7
Minucci, S.8
Porse, B.T.9
Marine, J.C.10
-
9
-
-
41149094512
-
Regulation of DNA repair throughout the cell cycle
-
Branzei D., Foiani M. Regulation of DNA repair throughout the cell cycle. Nat. Rev. Mol. Cell Biol. 2008, 9:297-308.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 297-308
-
-
Branzei, D.1
Foiani, M.2
-
10
-
-
39749114978
-
Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability
-
Bristow R.G., Hill R.P. Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability. Nat. Rev. Cancer 2008, 8:180-192.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 180-192
-
-
Bristow, R.G.1
Hill, R.P.2
-
11
-
-
1942503942
-
The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3
-
Cao R., Zhang Y. The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr. Opin. Genet. Dev. 2004, 14:155-164.
-
(2004)
Curr. Opin. Genet. Dev.
, vol.14
, pp. 155-164
-
-
Cao, R.1
Zhang, Y.2
-
12
-
-
33847369455
-
Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line
-
Chen M.S., Woodward W.A., Behbod F., Peddibhotla S., Alfaro M.P., Buchholz T.A., Rosen J.M. Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line. J. Cell Sci. 2007, 120:468-477.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 468-477
-
-
Chen, M.S.1
Woodward, W.A.2
Behbod, F.3
Peddibhotla, S.4
Alfaro, M.P.5
Buchholz, T.A.6
Rosen, J.M.7
-
13
-
-
33845191779
-
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
-
Chin K., DeVries S., Fridlyand J., Spellman P.T., Roydasgupta R., Kuo W.L., Lapuk A., Neve R.M., Qian Z., Ryder T., et al. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 2006, 10:529-541.
-
(2006)
Cancer Cell
, vol.10
, pp. 529-541
-
-
Chin, K.1
DeVries, S.2
Fridlyand, J.3
Spellman, P.T.4
Roydasgupta, R.5
Kuo, W.L.6
Lapuk, A.7
Neve, R.M.8
Qian, Z.9
Ryder, T.10
-
14
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn M., Cho R.W., Lobo N.A., Kalisky T., Dorie M.J., Kulp A.N., Qian D., Lam J.S., Ailles L.E., Wong M., et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009, 458:780-783.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
Kalisky, T.4
Dorie, M.J.5
Kulp, A.N.6
Qian, D.7
Lam, J.S.8
Ailles, L.E.9
Wong, M.10
-
15
-
-
0037136318
-
Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification
-
Difilippantonio M.J., Petersen S., Chen H.T., Johnson R., Jasin M., Kanaar R., Ried T., Nussenzweig A. Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification. J. Exp. Med. 2002, 196:469-480.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 469-480
-
-
Difilippantonio, M.J.1
Petersen, S.2
Chen, H.T.3
Johnson, R.4
Jasin, M.5
Kanaar, R.6
Ried, T.7
Nussenzweig, A.8
-
16
-
-
22544433759
-
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin
-
Ding Q., Xia W., Liu J.C., Yang J.Y., Lee D.F., Xia J., Bartholomeusz G., Li Y., Pan Y., Li Z., et al. Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol. Cell 2005, 19:159-170.
-
(2005)
Mol. Cell
, vol.19
, pp. 159-170
-
-
Ding, Q.1
Xia, W.2
Liu, J.C.3
Yang, J.Y.4
Lee, D.F.5
Xia, J.6
Bartholomeusz, G.7
Li, Y.8
Pan, Y.9
Li, Z.10
-
17
-
-
6344285329
-
Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM
-
Dodson H., Bourke E., Jeffers L.J., Vagnarelli P., Sonoda E., Takeda S., Earnshaw W.C., Merdes A., Morrison C. Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. EMBO J. 2004, 23:3864-3873.
-
(2004)
EMBO J.
, vol.23
, pp. 3864-3873
-
-
Dodson, H.1
Bourke, E.2
Jeffers, L.J.3
Vagnarelli, P.4
Sonoda, E.5
Takeda, S.6
Earnshaw, W.C.7
Merdes, A.8
Morrison, C.9
-
18
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
-
Dontu G., Abdallah W.M., Foley J.M., Jackson K.W., Clarke M.F., Kawamura M.J., Wicha M.S. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 2003, 17:1253-1270.
-
(2003)
Genes Dev.
, vol.17
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
Jackson, K.W.4
Clarke, M.F.5
Kawamura, M.J.6
Wicha, M.S.7
-
19
-
-
62149122634
-
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells
-
Ezhkova E., Pasolli H.A., Parker J.S., Stokes N., Su I.H., Hannon G., Tarakhovsky A., Fuchs E. Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell 2009, 136:1122-1135.
-
(2009)
Cell
, vol.136
, pp. 1122-1135
-
-
Ezhkova, E.1
Pasolli, H.A.2
Parker, J.S.3
Stokes, N.4
Su, I.H.5
Hannon, G.6
Tarakhovsky, A.7
Fuchs, E.8
-
20
-
-
0022474735
-
Large inverted duplications are associated with gene amplification
-
Ford M., Fried M. Large inverted duplications are associated with gene amplification. Cell 1986, 45:425-430.
-
(1986)
Cell
, vol.45
, pp. 425-430
-
-
Ford, M.1
Fried, M.2
-
21
-
-
44349088690
-
Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation
-
Guo W., Lasky J.L., Chang C.J., Mosessian S., Lewis X., Xiao Y., Yeh J.E., Chen J.Y., Iruela-Arispe M.L., Varella-Garcia M., Wu H. Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation. Nature 2008, 453:529-533.
-
(2008)
Nature
, vol.453
, pp. 529-533
-
-
Guo, W.1
Lasky, J.L.2
Chang, C.J.3
Mosessian, S.4
Lewis, X.5
Xiao, Y.6
Yeh, J.E.7
Chen, J.Y.8
Iruela-Arispe, M.L.9
Varella-Garcia, M.10
Wu, H.11
-
22
-
-
0025003475
-
DNA alterations at proto-oncogene loci and their clinical significance in operable non-small cell lung cancer
-
Hajj C., Akoum R., Bradley E., Paquin F., Ayoub J. DNA alterations at proto-oncogene loci and their clinical significance in operable non-small cell lung cancer. Cancer 1990, 66:733-739.
-
(1990)
Cancer
, vol.66
, pp. 733-739
-
-
Hajj, C.1
Akoum, R.2
Bradley, E.3
Paquin, F.4
Ayoub, J.5
-
23
-
-
56949091325
-
Molecular characterisation of the tumour microenvironment in breast cancer
-
Hu M., Polyak K. Molecular characterisation of the tumour microenvironment in breast cancer. Eur. J. Cancer 2008, 44:2760-2765.
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 2760-2765
-
-
Hu, M.1
Polyak, K.2
-
24
-
-
71349084002
-
AZD6244 enhances the anti-tumor activity of sorafenib in ectopic and orthotopic models of human hepatocellular carcinoma (HCC)
-
Huynh H., Ngo V.C., Koong H.N., Poon D., Choo S.P., Toh H.C., Thng C.H., Chow P., Ong H.S., Chung A., et al. AZD6244 enhances the anti-tumor activity of sorafenib in ectopic and orthotopic models of human hepatocellular carcinoma (HCC). J. Hepatol. 2010, 52:79-87.
-
(2010)
J. Hepatol.
, vol.52
, pp. 79-87
-
-
Huynh, H.1
Ngo, V.C.2
Koong, H.N.3
Poon, D.4
Choo, S.P.5
Toh, H.C.6
Thng, C.H.7
Chow, P.8
Ong, H.S.9
Chung, A.10
-
25
-
-
0034036430
-
Lung-targeted expression of the c-Raf-1 kinase in transgenic mice exposes a novel oncogenic character of the wild-type protein
-
Kerkhoff E., Fedorov L.M., Siefken R., Walter A.O., Papadopoulos T., Rapp U.R. Lung-targeted expression of the c-Raf-1 kinase in transgenic mice exposes a novel oncogenic character of the wild-type protein. Cell Growth Differ. 2000, 11:185-190.
-
(2000)
Cell Growth Differ.
, vol.11
, pp. 185-190
-
-
Kerkhoff, E.1
Fedorov, L.M.2
Siefken, R.3
Walter, A.O.4
Papadopoulos, T.5
Rapp, U.R.6
-
26
-
-
0141816752
-
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
-
Kleer C.G., Cao Q., Varambally S., Shen R., Ota I., Tomlins S.A., Ghosh D., Sewalt R.G., Otte A.P., Hayes D.F., et al. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc. Natl. Acad. Sci. USA 2003, 100:11606-11611.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11606-11611
-
-
Kleer, C.G.1
Cao, Q.2
Varambally, S.3
Shen, R.4
Ota, I.5
Tomlins, S.A.6
Ghosh, D.7
Sewalt, R.G.8
Otte, A.P.9
Hayes, D.F.10
-
27
-
-
0036040031
-
The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells
-
Konopleva M., Zhao S., Hu W., Jiang S., Snell V., Weidner D., Jackson C.E., Zhang X., Champlin R., Estey E., et al. The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells. Br. J. Haematol. 2002, 118:521-534.
-
(2002)
Br. J. Haematol.
, vol.118
, pp. 521-534
-
-
Konopleva, M.1
Zhao, S.2
Hu, W.3
Jiang, S.4
Snell, V.5
Weidner, D.6
Jackson, C.E.7
Zhang, X.8
Champlin, R.9
Estey, E.10
-
28
-
-
0037707818
-
Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis
-
Lessard J., Sauvageau G. Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis. Exp. Hematol. 2003, 31:567-585.
-
(2003)
Exp. Hematol.
, vol.31
, pp. 567-585
-
-
Lessard, J.1
Sauvageau, G.2
-
29
-
-
9144269759
-
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
-
Li Y., Welm B., Podsypanina K., Huang S., Chamorro M., Zhang X., Rowlands T., Egeblad M., Cowin P., Werb Z., et al. Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc. Natl. Acad. Sci. USA 2003, 100:15853-15858.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15853-15858
-
-
Li, Y.1
Welm, B.2
Podsypanina, K.3
Huang, S.4
Chamorro, M.5
Zhang, X.6
Rowlands, T.7
Egeblad, M.8
Cowin, P.9
Werb, Z.10
-
30
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
Li Z., Bao S., Wu Q., Wang H., Eyler C., Sathornsumetee S., Shi Q., Cao Y., Lathia J., McLendon R.E., et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 2009, 15:501-513.
-
(2009)
Cancer Cell
, vol.15
, pp. 501-513
-
-
Li, Z.1
Bao, S.2
Wu, Q.3
Wang, H.4
Eyler, C.5
Sathornsumetee, S.6
Shi, Q.7
Cao, Y.8
Lathia, J.9
McLendon, R.E.10
-
31
-
-
40349100163
-
BRCA1 regulates human mammary stem/progenitor cell fate
-
Liu S., Ginestier C., Charafe-Jauffret E., Foco H., Kleer C.G., Merajver S.D., Dontu G., Wicha M.S. BRCA1 regulates human mammary stem/progenitor cell fate. Proc. Natl. Acad. Sci. USA 2008, 105:1680-1685.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 1680-1685
-
-
Liu, S.1
Ginestier, C.2
Charafe-Jauffret, E.3
Foco, H.4
Kleer, C.G.5
Merajver, S.D.6
Dontu, G.7
Wicha, M.S.8
-
32
-
-
22244433866
-
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
-
Patrawala L., Calhoun T., Schneider-Broussard R., Zhou J., Claypool K., Tang D.G. Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic. Cancer Res. 2005, 65:6207-6219.
-
(2005)
Cancer Res.
, vol.65
, pp. 6207-6219
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Zhou, J.4
Claypool, K.5
Tang, D.G.6
-
33
-
-
73149110562
-
Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
-
Pece S., Tosoni D., Confalonieri S., Mazzarol G., Vecchi M., Ronzoni S., Bernard L., Viale G., Pelicci P.G., Di Fiore P.P. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 2010, 140:62-73.
-
(2010)
Cell
, vol.140
, pp. 62-73
-
-
Pece, S.1
Tosoni, D.2
Confalonieri, S.3
Mazzarol, G.4
Vecchi, M.5
Ronzoni, S.6
Bernard, L.7
Viale, G.8
Pelicci, P.G.9
Di Fiore, P.P.10
-
34
-
-
21344454219
-
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
-
Ponti D., Costa A., Zaffaroni N., Pratesi G., Petrangolini G., Coradini D., Pilotti S., Pierotti M.A., Daidone M.G. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res. 2005, 65:5506-5511.
-
(2005)
Cancer Res.
, vol.65
, pp. 5506-5511
-
-
Ponti, D.1
Costa, A.2
Zaffaroni, N.3
Pratesi, G.4
Petrangolini, G.5
Coradini, D.6
Pilotti, S.7
Pierotti, M.A.8
Daidone, M.G.9
-
35
-
-
34548789121
-
Reactive oxygen species, DNA damage, and error-prone repair: a model for genomic instability with progression in myeloid leukemia?
-
Rassool F.V., Gaymes T.J., Omidvar N., Brady N., Beurlet S., Pla M., Reboul M., Lea N., Chomienne C., Thomas N.S., et al. Reactive oxygen species, DNA damage, and error-prone repair: a model for genomic instability with progression in myeloid leukemia?. Cancer Res. 2007, 67:8762-8771.
-
(2007)
Cancer Res.
, vol.67
, pp. 8762-8771
-
-
Rassool, F.V.1
Gaymes, T.J.2
Omidvar, N.3
Brady, N.4
Beurlet, S.5
Pla, M.6
Reboul, M.7
Lea, N.8
Chomienne, C.9
Thomas, N.S.10
-
36
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T., Morrison S.J., Clarke M.F., Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 2001, 414:105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
37
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
Reya T., Duncan A.W., Ailles L., Domen J., Scherer D.C., Willert K., Hintz L., Nusse R., Weissman I.L. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003, 423:409-414.
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
Domen, J.4
Scherer, D.C.5
Willert, K.6
Hintz, L.7
Nusse, R.8
Weissman, I.L.9
-
38
-
-
39149086121
-
Stems cells and the pathways to aging and cancer
-
Rossi D.J., Jamieson C.H., Weissman I.L. Stems cells and the pathways to aging and cancer. Cell 2008, 132:681-696.
-
(2008)
Cell
, vol.132
, pp. 681-696
-
-
Rossi, D.J.1
Jamieson, C.H.2
Weissman, I.L.3
-
39
-
-
0036645397
-
TBX2 is preferentially amplified in BRCA1- and BRCA2-related breast tumors
-
Sinclair C.S., Adem C., Naderi A., Soderberg C.L., Johnson M., Wu K., Wadum L., Couch V.L., Sellers T.A., Schaid D., et al. TBX2 is preferentially amplified in BRCA1- and BRCA2-related breast tumors. Cancer Res. 2002, 62:3587-3591.
-
(2002)
Cancer Res.
, vol.62
, pp. 3587-3591
-
-
Sinclair, C.S.1
Adem, C.2
Naderi, A.3
Soderberg, C.L.4
Johnson, M.5
Wu, K.6
Wadum, L.7
Couch, V.L.8
Sellers, T.A.9
Schaid, D.10
-
40
-
-
69449086947
-
A vertebrate Polycomb response element governs segmentation of the posterior hindbrain
-
Sing A., Pannell D., Karaiskakis A., Sturgeon K., Djabali M., Ellis J., Lipshitz H.D., Cordes S.P. A vertebrate Polycomb response element governs segmentation of the posterior hindbrain. Cell 2009, 138:885-897.
-
(2009)
Cell
, vol.138
, pp. 885-897
-
-
Sing, A.1
Pannell, D.2
Karaiskakis, A.3
Sturgeon, K.4
Djabali, M.5
Ellis, J.6
Lipshitz, H.D.7
Cordes, S.P.8
-
41
-
-
33750379420
-
Polycomb silencers control cell fate, development and cancer
-
Sparmann A., van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nat. Rev. Cancer 2006, 6:846-856.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 846-856
-
-
Sparmann, A.1
van Lohuizen, M.2
-
42
-
-
0035902140
-
The Hedgehog and Wnt signalling pathways in cancer
-
Taipale J., Beachy P.A. The Hedgehog and Wnt signalling pathways in cancer. Nature 2001, 411:349-354.
-
(2001)
Nature
, vol.411
, pp. 349-354
-
-
Taipale, J.1
Beachy, P.A.2
-
43
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery J.P., Acloque H., Huang R.Y., Nieto M.A. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139:871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
44
-
-
54949146881
-
Ink4a/Arf regulation by let-7b and Hmga2: a genetic pathway governing stem cell aging
-
Tzatsos A., Bardeesy N. Ink4a/Arf regulation by let-7b and Hmga2: a genetic pathway governing stem cell aging. Cell Stem Cell 2008, 3:469-470.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 469-470
-
-
Tzatsos, A.1
Bardeesy, N.2
-
45
-
-
0035289717
-
Chromosomal stability and the DNA double-stranded break connection
-
van Gent D.C., Hoeijmakers J.H., Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat. Rev. Genet. 2001, 2:196-206.
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 196-206
-
-
van Gent, D.C.1
Hoeijmakers, J.H.2
Kanaar, R.3
-
46
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
Varambally S., Dhanasekaran S.M., Zhou M., Barrette T.R., Kumar-Sinha C., Sanda M.G., Ghosh D., Pienta K.J., Sewalt R.G., Otte A.P., et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 2002, 419:624-629.
-
(2002)
Nature
, vol.419
, pp. 624-629
-
-
Varambally, S.1
Dhanasekaran, S.M.2
Zhou, M.3
Barrette, T.R.4
Kumar-Sinha, C.5
Sanda, M.G.6
Ghosh, D.7
Pienta, K.J.8
Sewalt, R.G.9
Otte, A.P.10
-
47
-
-
52549087785
-
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
-
Visvader J.E., Lindeman G.J. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 2008, 8:755-768.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
48
-
-
48949119465
-
Cancer stem cell heterogeneity in hereditary breast cancer
-
Wicha M.S. Cancer stem cell heterogeneity in hereditary breast cancer. Breast Cancer Res. 2008, 10:105.
-
(2008)
Breast Cancer Res.
, vol.10
, pp. 105
-
-
Wicha, M.S.1
-
49
-
-
33644826522
-
The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells
-
Zeidler M., Varambally S., Cao Q., Chinnaiyan A.M., Ferguson D.O., Merajver S.D., Kleer C.G. The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells. Neoplasia 2005, 7:1011-1019.
-
(2005)
Neoplasia
, vol.7
, pp. 1011-1019
-
-
Zeidler, M.1
Varambally, S.2
Cao, Q.3
Chinnaiyan, A.M.4
Ferguson, D.O.5
Merajver, S.D.6
Kleer, C.G.7
-
50
-
-
49649085001
-
Identification of tumor-initiating cells in a p53-null mouse model of breast cancer
-
Zhang M., Behbod F., Atkinson R.L., Landis M.D., Kittrell F., Edwards D., Medina D., Tsimelzon A., Hilsenbeck S., Green J.E., et al. Identification of tumor-initiating cells in a p53-null mouse model of breast cancer. Cancer Res. 2008, 68:4674-4682.
-
(2008)
Cancer Res.
, vol.68
, pp. 4674-4682
-
-
Zhang, M.1
Behbod, F.2
Atkinson, R.L.3
Landis, M.D.4
Kittrell, F.5
Edwards, D.6
Medina, D.7
Tsimelzon, A.8
Hilsenbeck, S.9
Green, J.E.10
|