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Volumn 35, Issue 1, 2016, Pages

β-arrestin1 at the cross-road of endothelin-1 signaling in cancer

Author keywords

Cancer; Endothelin; Endothelin receptors; G protein coupled receptors; arrestin

Indexed keywords

ATRASENTAN; BETA ARRESTIN 1; BETA CATENIN; CISPLATIN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; G PROTEIN COUPLED RECEPTOR; MACITENTAN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; ZIBOTENTAN; ARRB1 PROTEIN, HUMAN; EDNRB PROTEIN, HUMAN;

EID: 84979699167     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-016-0401-4     Document Type: Review
Times cited : (42)

References (90)
  • 2
    • 84883153220 scopus 로고    scopus 로고
    • Endothelin 1 in cancer: Biological implications and therapeutic opportunities
    • 23884378
    • Rosanò L, Spinella F, Bagnato A. Endothelin 1 in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer. 2013;13:637-51.
    • (2013) Nat Rev Cancer , vol.13 , pp. 637-651
    • Rosanò, L.1    Spinella, F.2    Bagnato, A.3
  • 3
    • 84883530291 scopus 로고    scopus 로고
    • An emerging role for microRNA in the regulation of endothelin-1
    • Jacobs ME, Wingo CS, Cain BD. An emerging role for microRNA in the regulation of endothelin-1. Front Physiol. 2013;19:4-22.
    • (2013) Front Physiol , vol.19 , pp. 4-22
    • Jacobs, M.E.1    Wingo, C.S.2    Cain, B.D.3
  • 4
    • 84916221840 scopus 로고    scopus 로고
    • Emerging role of microRNAs in modulating endothelin-1 expression in gastric cancer
    • 1:CAS:528:DC%2BC2MXksVyisb4%3D 25394359
    • Tsai K, Hu L, Chen T, Li S, Ho M, Yu S, et al. Emerging role of microRNAs in modulating endothelin-1 expression in gastric cancer. Oncol Rep. 2015;33:485-93.
    • (2015) Oncol Rep , vol.33 , pp. 485-493
    • Tsai, K.1    Hu, L.2    Chen, T.3    Li, S.4    Ho, M.5    Yu, S.6
  • 5
    • 84866349767 scopus 로고    scopus 로고
    • MicroRNA-1 inhibits proliferation of hepatocarcinoma cells by targeting endothelin-1
    • Li D, Yang P, Li H, Cheng P, Zhang L, Wei D, et al. MicroRNA-1 inhibits proliferation of hepatocarcinoma cells by targeting endothelin-1. Life Sci. 2012;5:440-7.
    • (2012) Life Sci , vol.5 , pp. 440-447
    • Li, D.1    Yang, P.2    Li, H.3    Cheng, P.4    Zhang, L.5    Wei, D.6
  • 6
    • 0037317520 scopus 로고    scopus 로고
    • The endothelin axis: Emerging role in cancer
    • 1:CAS:528:DC%2BD3sXisVCqsr4%3D 12563310
    • Nelson J, Bagnato A, Battistini B, Nisen P. The endothelin axis: emerging role in cancer. Nat Rev Cancer. 2003;3:110-6.
    • (2003) Nat Rev Cancer , vol.3 , pp. 110-116
    • Nelson, J.1    Bagnato, A.2    Battistini, B.3    Nisen, P.4
  • 7
    • 84958012720 scopus 로고    scopus 로고
    • MiR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma
    • 26675258
    • Sestito R, Cianfrocca R, Rosanò L, Tocci P, Semprucci E, Di Castro V, et al. miR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma. Oncotarget. 2016;7:4009-23.
    • (2016) Oncotarget , vol.7 , pp. 4009-4023
    • Sestito, R.1    Cianfrocca, R.2    Rosanò, L.3    Tocci, P.4    Semprucci, E.5    Di Castro, V.6
  • 8
    • 80052359992 scopus 로고    scopus 로고
    • Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
    • 1:STN:280:DC%2BC3MnlvVOrsg%3D%3D
    • Shukla AK, Xiao K, Lefkowitz RJ. Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling. Trends Biochem Sci. 2011;36:57-69.
    • (2011) Trends Biochem Sci , vol.36 , pp. 57-69
    • Shukla, A.K.1    Xiao, K.2    Lefkowitz, R.J.3
  • 9
    • 84867581538 scopus 로고    scopus 로고
    • Comparison of human ETA and ETB receptor signaling via G-protein and β-arrestin pathways
    • 1:CAS:528:DC%2BC38XmtlWltb8%3D 22480514
    • Maguire JJ, Kuc RE, Pell VR, Green A, Brown M, Kumar S, et al. Comparison of human ETA and ETB receptor signaling via G-protein and β-arrestin pathways. Life Sci. 2012;91:544-9.
    • (2012) Life Sci , vol.91 , pp. 544-549
    • Maguire, J.J.1    Kuc, R.E.2    Pell, V.R.3    Green, A.4    Brown, M.5    Kumar, S.6
  • 11
    • 84976904251 scopus 로고    scopus 로고
    • Endothelin A receptor drives invadopodia function and cell motility through the β-arrestin/PDZ-RhoGEF pathway in ovarian carcinoma
    • Semprucci E, Tocci P, Cianfrocca R, Sestito R, Caprara V, Veglione M, et al. Endothelin A receptor drives invadopodia function and cell motility through the β-arrestin/PDZ-RhoGEF pathway in ovarian carcinoma. Oncogene. 2015. doi: 10.1038/onc.2015.403.
    • (2015) Oncogene
    • Semprucci, E.1    Tocci, P.2    Cianfrocca, R.3    Sestito, R.4    Caprara, V.5    Veglione, M.6
  • 12
    • 84966415524 scopus 로고    scopus 로고
    • Rapid Remodeling of Invadosomes by Gi-coupled Receptors: Dissecting the role of Rho GTPases
    • 1:CAS:528:DC%2BC28Xjt1eqsrY%3D 26740622
    • Kedziora KM, Leyton-Puig D, Argenzio E, Boumeester AJ, van Butselaar B, Yin T, et al. Rapid Remodeling of Invadosomes by Gi-coupled Receptors: dissecting the role of Rho GTPases. J Biol Chem. 2016;291:4323-33.
    • (2016) J Biol Chem , vol.291 , pp. 4323-4333
    • Kedziora, K.M.1    Leyton-Puig, D.2    Argenzio, E.3    Boumeester, A.J.4    Van Butselaar, B.5    Yin, T.6
  • 13
    • 84873465919 scopus 로고    scopus 로고
    • Endothelin receptor-A is required for the recruitment of antitumor T cells and modulates chemotherapy induction of cancer stem cells
    • 1:CAS:528:DC%2BC3sXktFOmurw%3D 23192269 3572000
    • Coffman L, Mooney C, Lim J, Bai S, Silva I, Gong Y, et al. Endothelin receptor-A is required for the recruitment of antitumor T cells and modulates chemotherapy induction of cancer stem cells. Cancer Biol Ther. 2013;14:184-92.
    • (2013) Cancer Biol Ther , vol.14 , pp. 184-192
    • Coffman, L.1    Mooney, C.2    Lim, J.3    Bai, S.4    Silva, I.5    Gong, Y.6
  • 14
    • 79954627096 scopus 로고    scopus 로고
    • Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells
    • 21220476
    • Rosanò L, Cianfrocca R, Spinella F, Di Castro V, Nicotra MR, Lucidi A, et al. Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells. Clin Cancer Res. 2011;17:2350-60.
    • (2011) Clin Cancer Res , vol.17 , pp. 2350-2360
    • Rosanò, L.1    Cianfrocca, R.2    Spinella, F.3    Di Castro, V.4    Nicotra, M.R.5    Lucidi, A.6
  • 15
    • 84918530212 scopus 로고    scopus 로고
    • Endothelin A receptor/β-arrestin signaling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy
    • 25377471
    • Rosanò L, Cianfrocca R, Tocci P, Spinella F, Di Castro V, Caprara V, et al. Endothelin A receptor/β-arrestin signaling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy. Cancer Res. 2014;74:7453-64.
    • (2014) Cancer Res , vol.74 , pp. 7453-7464
    • Rosanò, L.1    Cianfrocca, R.2    Tocci, P.3    Spinella, F.4    Di Castro, V.5    Caprara, V.6
  • 16
    • 84954304722 scopus 로고    scopus 로고
    • Macitentan blocks endothelin-1 receptor activation required for chemoresistant ovarian cancer cell plasticity and metastasis
    • Sestito R, Cianfrocca R, Rosanò L, Tocci P, Di Castro V, Caprara V, et al. Macitentan blocks endothelin-1 receptor activation required for chemoresistant ovarian cancer cell plasticity and metastasis. Life Sci. 2016;S0024-3205:30010-8.
    • (2016) Life Sci , vol.24 , pp. 30010-30018
    • Sestito, R.1    Cianfrocca, R.2    Rosanò, L.3    Tocci, P.4    Di Castro, V.5    Caprara, V.6
  • 17
    • 84884204620 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote growth and angiogenesis of tumors in mice
    • 1:CAS:528:DC%2BC38XhsFeqsrbK 23085755
    • Huang WH, Chang MC, Tsai KS, Hung MC, Chen HL, Hung SC. Mesenchymal stem cells promote growth and angiogenesis of tumors in mice. Oncogene. 2013;32:4343-54.
    • (2013) Oncogene , vol.32 , pp. 4343-4354
    • Huang, W.H.1    Chang, M.C.2    Tsai, K.S.3    Hung, M.C.4    Chen, H.L.5    Hung, S.C.6
  • 18
    • 84898016402 scopus 로고    scopus 로고
    • Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells
    • 1:CAS:528:DC%2BC3sXlvVCmtrg%3D 23584483
    • Wu MH, Huang CY, Lin JA, Wang SW, Peng CY, Cheng HC, et al. Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells. Oncogene. 2014;33:1725-35.
    • (2014) Oncogene , vol.33 , pp. 1725-1735
    • Wu, M.H.1    Huang, C.Y.2    Lin, J.A.3    Wang, S.W.4    Peng, C.Y.5    Cheng, H.C.6
  • 19
    • 84898666129 scopus 로고    scopus 로고
    • The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor
    • 1:CAS:528:DC%2BC2cXmtVOhsb4%3D 24473118 3988429
    • Spinella F, Caprara V, Cianfrocca R, Rosanò L, Di Castro V, Garrafa E, et al. The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor. Carcinogenesis. 2014;35:840-8.
    • (2014) Carcinogenesis , vol.35 , pp. 840-848
    • Spinella, F.1    Caprara, V.2    Cianfrocca, R.3    Rosanò, L.4    Di Castro, V.5    Garrafa, E.6
  • 21
    • 38049000452 scopus 로고    scopus 로고
    • Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy
    • 1:CAS:528:DC%2BD1cXisVWjtw%3D%3D 18157142
    • Buckanovich RJ, Facciabene A, Kim S, Benencia F, Sasaroli D, Balint K, et al. Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy. Nat Med. 2008;14:28-36.
    • (2008) Nat Med , vol.14 , pp. 28-36
    • Buckanovich, R.J.1    Facciabene, A.2    Kim, S.3    Benencia, F.4    Sasaroli, D.5    Balint, K.6
  • 22
    • 84959341382 scopus 로고    scopus 로고
    • Endothelin B receptor expression in malignant gliomas: The perivascular immune escape mechanism of gliomas
    • 1:CAS:528:DC%2BC2MXitVWrtb%2FL 26645886
    • Nakashima S, Sugita Y, Miyoshi H, Arakawa F, Muta H, Ishibashi Y, et al. Endothelin B receptor expression in malignant gliomas: the perivascular immune escape mechanism of gliomas. J Neurooncol. 2016;127:23-32.
    • (2016) J Neurooncol , vol.127 , pp. 23-32
    • Nakashima, S.1    Sugita, Y.2    Miyoshi, H.3    Arakawa, F.4    Muta, H.5    Ishibashi, Y.6
  • 23
    • 84902449230 scopus 로고    scopus 로고
    • Endothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptor
    • 24901342 4046988
    • Maffei R, Bulgarelli J, Fiorcari S, Martinelli S, Castelli I, Valenti V, et al. Endothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptor. PLoS One. 2014;9(6):e98818.
    • (2014) PLoS One , vol.9 , Issue.6 , pp. e98818
    • Maffei, R.1    Bulgarelli, J.2    Fiorcari, S.3    Martinelli, S.4    Castelli, I.5    Valenti, V.6
  • 24
    • 84922762369 scopus 로고    scopus 로고
    • Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells
    • 25008093 4232084
    • Kim SW, Choi HJ, Lee HJ, He J, Wu Q, Langley RR, et al. Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells. Neuro Oncol. 2014;16:1585-98.
    • (2014) Neuro Oncol , vol.16 , pp. 1585-1598
    • Kim, S.W.1    Choi, H.J.2    Lee, H.J.3    He, J.4    Wu, Q.5    Langley, R.R.6
  • 25
    • 84945588133 scopus 로고    scopus 로고
    • Macitentan, a dual endothelin receptor antagonist, in combination with Temozolomide leads to glioblastoma regression and long-term survival in mice
    • 1:CAS:528:DC%2BC2MXhs1yltr3L 26106074 4780217
    • Kim SJ, Lee HJ, Kim MS, Choi HJ, He J, Wu Q, et al. Macitentan, a dual endothelin receptor antagonist, in combination with Temozolomide leads to glioblastoma regression and long-term survival in mice. Clin Cancer Res. 2015;21:4630-41.
    • (2015) Clin Cancer Res , vol.21 , pp. 4630-4641
    • Kim, S.J.1    Lee, H.J.2    Kim, M.S.3    Choi, H.J.4    He, J.5    Wu, Q.6
  • 26
    • 84862961320 scopus 로고    scopus 로고
    • Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist
    • 22348175 3281406
    • Kim SJ, Kim JS, Kim SW, Yun SJ, He J, Brantley E, et al. Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist. Transl Oncol. 2012;5:39-47.
    • (2012) Transl Oncol , vol.5 , pp. 39-47
    • Kim, S.J.1    Kim, J.S.2    Kim, S.W.3    Yun, S.J.4    He, J.5    Brantley, E.6
  • 27
    • 79951501975 scopus 로고    scopus 로고
    • Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer
    • 1:CAS:528:DC%2BC3MXivVensrk%3D 21403842 3033595
    • Kim SJ, Kim JS, Kim SW, Brantley E, Yun SJ, He J, et al. Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer. Neoplasia. 2011;13:167-79.
    • (2011) Neoplasia , vol.13 , pp. 167-179
    • Kim, S.J.1    Kim, J.S.2    Kim, S.W.3    Brantley, E.4    Yun, S.J.5    He, J.6
  • 28
    • 62449145673 scopus 로고    scopus 로고
    • Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis
    • 19202075 2650347
    • Rosanò L, Cianfrocca R, Masi S, Spinella F, Di Castro V, Biroccio A, et al. Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis. Proc Natl Acad Sci. 2009;106:2806-11.
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 2806-2811
    • Rosanò, L.1    Cianfrocca, R.2    Masi, S.3    Spinella, F.4    Di Castro, V.5    Biroccio, A.6
  • 29
    • 84886100276 scopus 로고    scopus 로고
    • β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling
    • 23208497
    • Rosanò L, Cianfrocca R, Tocci P, Spinella F, Di Castro V, Spadaro F, et al. β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling. Oncogene. 2013;32:5066-77.
    • (2013) Oncogene , vol.32 , pp. 5066-5077
    • Rosanò, L.1    Cianfrocca, R.2    Tocci, P.3    Spinella, F.4    Di Castro, V.5    Spadaro, F.6
  • 30
    • 78650957612 scopus 로고    scopus 로고
    • Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer
    • 1:CAS:528:DC%2BC3MXis1yntA%3D%3D 21183790
    • Said N, Smith S, Sanchez-Carbayo M, Theodorescu D. Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer. J Clin Invest. 2011;121:132-47.
    • (2011) J Clin Invest , vol.121 , pp. 132-147
    • Said, N.1    Smith, S.2    Sanchez-Carbayo, M.3    Theodorescu, D.4
  • 31
    • 84907046942 scopus 로고    scopus 로고
    • The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation
    • 25168820 4167278
    • Salazar N, Muñoz D, Kallifatidis G, Singh RK, Jordà M, Lokeshwar BL. The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation. Mol Cancer. 2014;13:198.
    • (2014) Mol Cancer , vol.13 , pp. 198
    • Salazar, N.1    Muñoz, D.2    Kallifatidis, G.3    Singh, R.K.4    Jordà, M.5    Lokeshwar, B.L.6
  • 32
    • 84969130046 scopus 로고    scopus 로고
    • β-Arrestin-2 Counters CXCR7-Mediated EGFR Transactivation and Proliferation
    • 1:CAS:528:DC%2BC28XnslCqtb0%3D 26921391
    • Kallifatidis G, Munoz D, Singh RK, Salazar N, Hoy JJ, Lokeshwar BL. β-Arrestin-2 Counters CXCR7-Mediated EGFR Transactivation and Proliferation. Mol Cancer Res. 2016;14(5):493-503.
    • (2016) Mol Cancer Res , vol.14 , Issue.5 , pp. 493-503
    • Kallifatidis, G.1    Munoz, D.2    Singh, R.K.3    Salazar, N.4    Hoy, J.J.5    Lokeshwar, B.L.6
  • 33
    • 31944452649 scopus 로고    scopus 로고
    • Role of beta-arrestin 1 in the metastatic progression of colorectal cancer
    • 1:CAS:528:DC%2BD28Xhs1Gns7c%3D 16432186 1360588
    • Buchanan FG, Gorden DL, Matta P, Shi Q, Matrisian LM, DuBois RN. Role of beta-arrestin 1 in the metastatic progression of colorectal cancer. Proc Natl Acad Sci. 2006;103:1492-7.
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 1492-1497
    • Buchanan, F.G.1    Gorden, D.L.2    Matta, P.3    Shi, Q.4    Matrisian, L.M.5    DuBois, R.N.6
  • 34
    • 67650485948 scopus 로고    scopus 로고
    • Obestatin stimulates Akt signaling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation
    • 1:CAS:528:DC%2BD1MXptlOhurY%3D 19153210
    • Alvarez CJ, Lodeiro M, Theodoropoulou M, Camiña JP, Casanueva FF, Pazos Y. Obestatin stimulates Akt signaling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation. Endocr Relat Cancer. 2009;16:599-611.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 599-611
    • Alvarez, C.J.1    Lodeiro, M.2    Theodoropoulou, M.3    Camiña, J.P.4    Casanueva, F.F.5    Pazos, Y.6
  • 35
    • 80054782210 scopus 로고    scopus 로고
    • β-arrestin-dependent actin reorganization: Bringing the right players together at the leading edge
    • 1:CAS:528:DC%2BC3MXhs1ektbzI 21836019
    • Min J, Defea K. β-arrestin-dependent actin reorganization: bringing the right players together at the leading edge. Mol Pharmacol. 2011;80:760-8.
    • (2011) Mol Pharmacol , vol.80 , pp. 760-768
    • Min, J.1    Defea, K.2
  • 36
    • 84873640501 scopus 로고    scopus 로고
    • Pseudopodial and β-arrestin-interacting proteomes from migrating breast cancer cells upon PAR2 activation
    • 1:CAS:528:DC%2BC3sXktFaktb0%3D 23313222
    • Parisis N, Metodieva G, Metodiev MV. Pseudopodial and β-arrestin-interacting proteomes from migrating breast cancer cells upon PAR2 activation. J Proteomics. 2013;80:91-106.
    • (2013) J Proteomics , vol.80 , pp. 91-106
    • Parisis, N.1    Metodieva, G.2    Metodiev, M.V.3
  • 37
    • 77956998735 scopus 로고    scopus 로고
    • Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)
    • 1:CAS:528:DC%2BC3cXhtFSnsb%2FI 20686112 2930550
    • Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, et al. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proc Natl Acad Sci. 2010;107:15299-304.
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 15299-15304
    • Xiao, K.1    Sun, J.2    Kim, J.3    Rajagopal, S.4    Zhai, B.5    Villén, J.6    Haas, W.7
  • 38
    • 84858612683 scopus 로고    scopus 로고
    • Identification of a nuclear localization sequencein β-arrestin-1 and its functional implications
    • 1:CAS:528:DC%2BC38XjvVehtbY%3D 22267743 3308787
    • Hoeppner CZ, Cheng N, Ye RD. Identification of a nuclear localization sequencein β-arrestin-1 and its functional implications. J Biol Chem. 2012;287:8932-43.
    • (2012) J Biol Chem , vol.287 , pp. 8932-8943
    • Hoeppner, C.Z.1    Cheng, N.2    Ye, R.D.3
  • 39
    • 28344452845 scopus 로고    scopus 로고
    • A nuclear function of beta-arrestin1 in GPCR signaling: Regulation of histone acetylation and gene transcription
    • 1:CAS:528:DC%2BD2MXhtlWntLjE 16325578
    • Kang J, Shi Y, Xiang B, Qu B, Su W, Zhu M, et al. A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription. Cell. 2005;123:833-47.
    • (2005) Cell , vol.123 , pp. 833-847
    • Kang, J.1    Shi, Y.2    Xiang, B.3    Qu, B.4    Su, W.5    Zhu, M.6
  • 40
    • 79951923011 scopus 로고    scopus 로고
    • ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors
    • 1:CAS:528:DC%2BC3MXitlejsLw%3D 21212384 3039728
    • Dasgupta P, Rizwani W, Pillai S, Davis R, Banerjee S, Hug K, et al. ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors. J Natl Cancer Inst. 2011;103:317-33.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 317-333
    • Dasgupta, P.1    Rizwani, W.2    Pillai, S.3    Davis, R.4    Banerjee, S.5    Hug, K.6
  • 41
    • 84916919339 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors induce c-Kit ligand/Stem Cell Factor and promote stemness in an ARRB1/β-arrestin-1 dependent manner in NSCLC
    • 25401222 4279388
    • Perumal D, Pillai S, Nguyen J, Schaal C, Coppola D, Chellappan SP. Nicotinic acetylcholine receptors induce c-Kit ligand/Stem Cell Factor and promote stemness in an ARRB1/β-arrestin-1 dependent manner in NSCLC. Oncotarget. 2014;5:10486-502.
    • (2014) Oncotarget , vol.5 , pp. 10486-10502
    • Perumal, D.1    Pillai, S.2    Nguyen, J.3    Schaal, C.4    Coppola, D.5    Chellappan, S.P.6
  • 42
    • 84935867705 scopus 로고    scopus 로고
    • β-arrestin-1 mediates nicotine-induced metastasis throughE2F1 target genes that modulate epithelial-mesenchymal transition
    • 1:CAS:528:DC%2BC2MXktlKmu7k%3D 25600647 4359962
    • Pillai S, Trevino J, Rawal B, Singh S, Kovacs M, Li X, et al. β-arrestin-1 mediates nicotine-induced metastasis throughE2F1 target genes that modulate epithelial-mesenchymal transition. Cancer Res. 2015;75:1009-20.
    • (2015) Cancer Res , vol.75 , pp. 1009-1020
    • Pillai, S.1    Trevino, J.2    Rawal, B.3    Singh, S.4    Kovacs, M.5    Li, X.6
  • 43
    • 84862798966 scopus 로고    scopus 로고
    • Nicotine-mediated induction of E-selectin in aortic endothelial cells requires Src kinase and E2F1transcriptional activity
    • 1:CAS:528:DC%2BC38XhvFejt7g%3D 22240023 3273677
    • Alamanda V, Singh S, Lawrence NJ, Chellappan SP. Nicotine-mediated induction of E-selectin in aortic endothelial cells requires Src kinase and E2F1transcriptional activity. Biochem Biophys Res Commun. 2012;418:56-61.
    • (2012) Biochem Biophys Res Commun , vol.418 , pp. 56-61
    • Alamanda, V.1    Singh, S.2    Lawrence, N.J.3    Chellappan, S.P.4
  • 44
    • 84905278270 scopus 로고    scopus 로고
    • β-Arrestin1 promotes the progression of chronic myeloid leukaemia byregulating BCR/ABL H4 acetylation
    • 1:CAS:528:DC%2BC2cXhtVagsbbL 24937675 4119990
    • Qin R, Li K, Qi X, Zhou X, Wang L, Zhang P, et al. β-Arrestin1 promotes the progression of chronic myeloid leukaemia byregulating BCR/ABL H4 acetylation. Br J Cancer. 2014;111:568-76.
    • (2014) Br J Cancer , vol.111 , pp. 568-576
    • Qin, R.1    Li, K.2    Qi, X.3    Zhou, X.4    Wang, L.5    Zhang, P.6
  • 45
    • 84920434344 scopus 로고    scopus 로고
    • β-Arrestin1 promotes the self-renewal of the leukemia-initiating cell enriched subpopulation in B-lineage acute lymphoblastic leukemia related to DNMT1 activity
    • 1:CAS:528:DC%2BC2cXitVWhurjE 25444908
    • Shu Y, Zhou X, Qi X, Liu S, Li K, Tan J, et al. β-Arrestin1 promotes the self-renewal of the leukemia-initiating cell enriched subpopulation in B-lineage acute lymphoblastic leukemia related to DNMT1 activity. Cancer Lett. 2015;357:170-8.
    • (2015) Cancer Lett , vol.357 , pp. 170-178
    • Shu, Y.1    Zhou, X.2    Qi, X.3    Liu, S.4    Li, K.5    Tan, J.6
  • 47
    • 84855927182 scopus 로고    scopus 로고
    • β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression
    • 1:CAS:528:DC%2BC3MXnslSmurk%3D 21685944
    • Shenoy SK, Han S, Zhao YL, Hara MR, Oliver T, Cao Y, et al. β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression. Oncogene. 2012;31:282-92.
    • (2012) Oncogene , vol.31 , pp. 282-292
    • Shenoy, S.K.1    Han, S.2    Zhao, Y.L.3    Hara, M.R.4    Oliver, T.5    Cao, Y.6
  • 48
    • 84903288729 scopus 로고    scopus 로고
    • Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer
    • 1:CAS:528:DC%2BC2cXhtlKnu7zE 24837709 4194125
    • Zecchini V, Madhu B, Russell R, Pértega-Gomes N, Warren A, Gaude E, et al. Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer. EMBO J. 2014;33:1365-82.
    • (2014) EMBO J , vol.33 , pp. 1365-1382
    • Zecchini, V.1    Madhu, B.2    Russell, R.3    Pértega-Gomes, N.4    Warren, A.5    Gaude, E.6
  • 49
    • 84935851247 scopus 로고    scopus 로고
    • β-Arrestin1 enhances hepatocellular carcinogenesis through inflammation-mediated Akt signaling
    • 1:CAS:528:DC%2BC2MXhtF2kt7jL 26077142
    • Yang Y, Guo Y, Tan S, Ke B, Tao J, Liu H, et al. β-Arrestin1 enhances hepatocellular carcinogenesis through inflammation-mediated Akt signaling. Nat Commun. 2015;6:7369.
    • (2015) Nat Commun , vol.6 , pp. 7369
    • Yang, Y.1    Guo, Y.2    Tan, S.3    Ke, B.4    Tao, J.5    Liu, H.6
  • 50
    • 84928150216 scopus 로고    scopus 로고
    • β-arrestin 2 is associated with multidrug resistance in breast cancer cells through regulating MDR1 gene expression
    • 1:CAS:528:DC%2BC28XpsFSnsLo%3D 25973019 4396277
    • Jing X, Zhang H, Hu J, Su P, Zhang W, Jia M, et al. β-arrestin 2 is associated with multidrug resistance in breast cancer cells through regulating MDR1 gene expression. Int J Clin Exp Pathol. 2015;8:1354-63.
    • (2015) Int J Clin Exp Pathol , vol.8 , pp. 1354-1363
    • Jing, X.1    Zhang, H.2    Hu, J.3    Su, P.4    Zhang, W.5    Jia, M.6
  • 51
    • 80052832196 scopus 로고    scopus 로고
    • A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
    • 1:CAS:528:DC%2BC3MXhtFersLnE 21857681 3628753
    • Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, et al. A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature. 2011;477:349-53.
    • (2011) Nature , vol.477 , pp. 349-353
    • Hara, M.R.1    Kovacs, J.J.2    Whalen, E.J.3    Rajagopal, S.4    Strachan, R.T.5    Grant, W.6
  • 52
    • 84975062691 scopus 로고    scopus 로고
    • Ubiquitin-related roles of β-arrestins in endocytic trafficking and signal transduction
    • 1:CAS:528:DC%2BC28XhvVShs78%3D 26790995
    • Jean-Charles PY, Rajiv V, Shenoy SK. Ubiquitin-related roles of β-arrestins in endocytic trafficking and signal transduction. J Cell Physiol. 2016;231:2071-80.
    • (2016) J Cell Physiol , vol.231 , pp. 2071-2080
    • Jean-Charles, P.Y.1    Rajiv, V.2    Shenoy, S.K.3
  • 53
    • 84932618738 scopus 로고    scopus 로고
    • β-Arrestin2 contributes to cell viability and proliferation via the down-regulation of FOXO1 in castration-resistant prostate cancer
    • 1:CAS:528:DC%2BC2MXhtVGmtLbI 25752515
    • Duan X, Kong Z, Liu Y, Zeng Z, Li S, Wu W, et al. β-Arrestin2 contributes to cell viability and proliferation via the down-regulation of FOXO1 in castration-resistant prostate cancer. J Cell Physiol. 2015;230:2371-81.
    • (2015) J Cell Physiol , vol.230 , pp. 2371-2381
    • Duan, X.1    Kong, Z.2    Liu, Y.3    Zeng, Z.4    Li, S.5    Wu, W.6
  • 54
    • 84935421370 scopus 로고    scopus 로고
    • β-arrestin1 over-expression is associated with an unfavorable prognosis in lung adenocarcinomas and correlated with vascular endothelial growth factor
    • 1:CAS:528:DC%2BC28XpsFyrsrY%3D 26097560 4466947
    • Qiu C, Zheng C, Zhu L, Qu X, Shen H, Du J. β-arrestin1 over-expression is associated with an unfavorable prognosis in lung adenocarcinomas and correlated with vascular endothelial growth factor. Int J Clin Exp Pathol. 2015;8:3785-93.
    • (2015) Int J Clin Exp Pathol , vol.8 , pp. 3785-3793
    • Qiu, C.1    Zheng, C.2    Zhu, L.3    Qu, X.4    Shen, H.5    Du, J.6
  • 55
    • 84940435107 scopus 로고    scopus 로고
    • Co-expression of β-arrestin1 and NF-kB is associated with cancer progression and poor prognosis in lung adenocarcinoma
    • 1:CAS:528:DC%2BC2MXlslCgsbg%3D 25820700
    • Yu J, Wang L, Zhang T, Shen H, Dong W, Ni Y, et al. Co-expression of β-arrestin1 and NF-kB is associated with cancer progression and poor prognosis in lung adenocarcinoma. Tumour Biol. 2015;36:6551-8.
    • (2015) Tumour Biol , vol.36 , pp. 6551-6558
    • Yu, J.1    Wang, L.2    Zhang, T.3    Shen, H.4    Dong, W.5    Ni, Y.6
  • 56
    • 84954290049 scopus 로고    scopus 로고
    • Endothelin-1/endothelin A receptor axis activates RhoA GTPase in epithelial ovarian cancer
    • Tocci P, Caprara V, Cianfrocca R, Sestito R, Di Castro V, Bagnato A, et al. Endothelin-1/endothelin A receptor axis activates RhoA GTPase in epithelial ovarian cancer. Life Sci. 2016. doi: 10.1016/j.lfs.2016.01.008.
    • (2016) Life Sci
    • Tocci, P.1    Caprara, V.2    Cianfrocca, R.3    Sestito, R.4    Di Castro, V.5    Bagnato, A.6
  • 57
    • 84956731722 scopus 로고    scopus 로고
    • KISS1R signaling promotes invadopodia formation in human breast cancer cell via β-arrestin2/ERK
    • 1:CAS:528:DC%2BC28XitV2ksQ%3D%3D 26721186
    • Goertzen CG, Dragan M, Turley E, Babwah AV, Bhattacharya M. KISS1R signaling promotes invadopodia formation in human breast cancer cell via β-arrestin2/ERK. Cell Signal. 2016;28:165-76.
    • (2016) Cell Signal , vol.28 , pp. 165-176
    • Goertzen, C.G.1    Dragan, M.2    Turley, E.3    Babwah, A.V.4    Bhattacharya, M.5
  • 58
    • 84975457701 scopus 로고    scopus 로고
    • Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression
    • Cianfrocca R, Tocci P, Rosanò L, Caprara V, Sestito R, Di Castro V, et al. Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression. Oncotarget. 2016. doi: 10.18632/oncotarget.7461.
    • (2016) Oncotarget
    • Cianfrocca, R.1    Tocci, P.2    Rosanò, L.3    Caprara, V.4    Sestito, R.5    Di Castro, V.6
  • 59
    • 84894528689 scopus 로고    scopus 로고
    • β-arrestin 1 is required for endothelin-1-induced NF-kB activation in ovarian cancer cells
    • 1:CAS:528:DC%2BC2cXjsVKkurw%3D 24530737
    • Cianfrocca R, Tocci P, Semprucci E, Spinella F, Di Castro V, Bagnato A, et al. β-arrestin 1 is required for endothelin-1-induced NF-kB activation in ovarian cancer cells. Life Sci. 2014;118:179-84.
    • (2014) Life Sci , vol.118 , pp. 179-184
    • Cianfrocca, R.1    Tocci, P.2    Semprucci, E.3    Spinella, F.4    Di Castro, V.5    Bagnato, A.6
  • 60
    • 84907638077 scopus 로고    scopus 로고
    • Endothelin-1/endothelin A receptor-mediated biased signaling is a new player in modulating human ovarian cancer cell tumorigenesis
    • 1:CAS:528:DC%2BC2cXhs1Kmsb%2FF 25194819 4254323
    • Teoh JP, Park KM, Wang Y, Hu Q, Kim S, Wu G, et al. Endothelin-1/endothelin A receptor-mediated biased signaling is a new player in modulating human ovarian cancer cell tumorigenesis. Cell Signal. 2014;26:2885-95.
    • (2014) Cell Signal , vol.26 , pp. 2885-2895
    • Teoh, J.P.1    Park, K.M.2    Wang, Y.3    Hu, Q.4    Kim, S.5    Wu, G.6
  • 61
    • 78650195613 scopus 로고    scopus 로고
    • Beta-arrestin-1 mediates the endothelin-1-induced activation of Akt and integrin-linked kinase
    • 1:CAS:528:DC%2BC3cXpsFyitLY%3D 20725137
    • Cianfrocca R, Rosanò L, Spinella F, Di Castro V, Natali PG, Bagnato A. Beta-arrestin-1 mediates the endothelin-1-induced activation of Akt and integrin-linked kinase. Can J Physiol Pharmacol. 2010;88:796-801.
    • (2010) Can J Physiol Pharmacol , vol.88 , pp. 796-801
    • Cianfrocca, R.1    Rosanò, L.2    Spinella, F.3    Di Castro, V.4    Natali, P.G.5    Bagnato, A.6
  • 62
    • 84893098491 scopus 로고    scopus 로고
    • Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers
    • 1:CAS:528:DC%2BC2cXptVyqtw%3D%3D 24398389 3915512
    • Schaal C, Chellappan SP. Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers. Mol Cancer Res. 2014;12:14-23.
    • (2014) Mol Cancer Res , vol.12 , pp. 14-23
    • Schaal, C.1    Chellappan, S.P.2
  • 63
    • 33751336914 scopus 로고    scopus 로고
    • Nicotine-mediated cell proliferation and angiogenesis: New twists to an old story
    • 1:CAS:528:DC%2BD2sXmvVyntA%3D%3D 17102610
    • Dasgupta P, Chellappan SP. Nicotine-mediated cell proliferation and angiogenesis: new twists to an old story. Cell Cycle. 2006;5:2324-8.
    • (2006) Cell Cycle. , vol.5 , pp. 2324-2328
    • Dasgupta, P.1    Chellappan, S.P.2
  • 64
    • 84873894317 scopus 로고    scopus 로고
    • β-Arrestin-1 and Mcl-1 modulate self-renewal growth of cancer stem-like side-population cells in non-small cell lung cancer
    • 1:CAS:528:DC%2BC3sXjtlCls70%3D 23418490 3572139
    • Singh S, Bora-Singhal N, Kroeger J, Laklai H, Chellappan SP. β-Arrestin-1 and Mcl-1 modulate self-renewal growth of cancer stem-like side-population cells in non-small cell lung cancer. PLoS One. 2013;8:e55982.
    • (2013) PLoS One , vol.8 , pp. e55982
    • Singh, S.1    Bora-Singhal, N.2    Kroeger, J.3    Laklai, H.4    Chellappan, S.P.5
  • 65
    • 33746672599 scopus 로고    scopus 로고
    • Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways
    • 1:CAS:528:DC%2BD28XnvF2mt7s%3D 16862215 1513051
    • Dasgupta P, Rastogi S, Pillai S, Ordonez-Ercan D, Morris M, Haura E, et al. Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways. J Clin Invest. 2006;116:2208-17.
    • (2006) J Clin Invest , vol.116 , pp. 2208-2217
    • Dasgupta, P.1    Rastogi, S.2    Pillai, S.3    Ordonez-Ercan, D.4    Morris, M.5    Haura, E.6
  • 66
    • 77951157434 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome
    • 1:CAS:528:DC%2BC3cXkslSrurw%3D 20353998 2855782
    • Kim JI, Lakshmikanthan V, Frilot N, Daaka Y. Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome. Mol Cancer Res. 2010;8:569-77.
    • (2010) Mol Cancer Res , vol.8 , pp. 569-577
    • Kim, J.I.1    Lakshmikanthan, V.2    Frilot, N.3    Daaka, Y.4
  • 67
    • 80053526319 scopus 로고    scopus 로고
    • β-arrestin2 mediates β-2 adrenergic receptor signaling inducing prostate cancer cell progression
    • 1:CAS:528:DC%2BC3MXhsFSku77P 21833475
    • Zhang P, He X, Tan J, Zhou X, Zou L. β-arrestin2 mediates β-2 adrenergic receptor signaling inducing prostate cancer cell progression. Oncol Rep. 2011;26:1471-7.
    • (2011) Oncol Rep , vol.26 , pp. 1471-1477
    • Zhang, P.1    He, X.2    Tan, J.3    Zhou, X.4    Zou, L.5
  • 68
    • 67249152481 scopus 로고    scopus 로고
    • Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer
    • 1:CAS:528:DC%2BD1MXot1Cgur0%3D 19458261 2695075
    • Lakshmikanthan V, Zou L, Kim JI, Michal A, Nie Z, Messias NC, et al. Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer. Proc Natl Acad Sci. 2009;106:9379-84.
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 9379-9384
    • Lakshmikanthan, V.1    Zou, L.2    Kim, J.I.3    Michal, A.4    Nie, Z.5    Messias, N.C.6
  • 69
    • 79955936152 scopus 로고    scopus 로고
    • Elevated β-arrestin1 expression correlated with risk stratification in acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC3MXltFektLs%3D 21479985
    • Liu H, Long J, Zhang PH, Li K, Tan JJ, Sun B, et al. Elevated β-arrestin1 expression correlated with risk stratification in acute lymphoblastic leukemia. Int J Hematol. 2011;93:494-501.
    • (2011) Int J Hematol , vol.93 , pp. 494-501
    • Liu, H.1    Long, J.2    Zhang, P.H.3    Li, K.4    Tan, J.J.5    Sun, B.6
  • 70
    • 84864507841 scopus 로고    scopus 로고
    • β-Arrestin2 mediates the initiation and progression of myeloid leukemia
    • 1:CAS:528:DC%2BC38XhtleqsrfI 22773819 3411976
    • Fereshteh M, Ito T, Kovacs JJ, Zhao C, Kwon HY, Tornini V, et al. β-Arrestin2 mediates the initiation and progression of myeloid leukemia. Proc Natl Acad Sci. 2012;109:12532-7.
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 12532-12537
    • Fereshteh, M.1    Ito, T.2    Kovacs, J.J.3    Zhao, C.4    Kwon, H.Y.5    Tornini, V.6
  • 71
    • 84899694169 scopus 로고    scopus 로고
    • Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth
    • 24736311 3988186
    • Kotula JW, Sun J, Li M, Pratico ED, Fereshteh MP, Ahrens DP, et al. Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth. PLoS One. 2014;9, e93441.
    • (2014) PLoS One , vol.9 , pp. e93441
    • Kotula, J.W.1    Sun, J.2    Li, M.3    Pratico, E.D.4    Fereshteh, M.P.5    Ahrens, D.P.6
  • 72
    • 84857433083 scopus 로고    scopus 로고
    • Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling
    • 1:CAS:528:DC%2BC38Xjs1Wmt7c%3D 22315403 3286958
    • Bonnans C, Flacelière M, Grillet F, Dantec C, Desvignes JP, Pannequin J, et al. Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling. Proc Natl Acad Sci. 2012;109:3047-52.
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 3047-3052
    • Bonnans, C.1    Flacelière, M.2    Grillet, F.3    Dantec, C.4    Desvignes, J.P.5    Pannequin, J.6
  • 73
    • 84884385226 scopus 로고    scopus 로고
    • Progastrin stimulates colonic cell proliferation via CCK2R- and β-arrestin-dependent suppression of BMP2
    • 1:CAS:528:DC%2BC3sXhsVOntL3E 23891976
    • Jin G, Westphalen CB, Hayakawa Y, Worthley DL, Asfaha S, Yang X, et al. Progastrin stimulates colonic cell proliferation via CCK2R- and β-arrestin-dependent suppression of BMP2. Gastroenterology. 2013;145:820-30.
    • (2013) Gastroenterology , vol.145 , pp. 820-830
    • Jin, G.1    Westphalen, C.B.2    Hayakawa, Y.3    Worthley, D.L.4    Asfaha, S.5    Yang, X.6
  • 74
    • 84877742337 scopus 로고    scopus 로고
    • Deficiency of phospholipase A2 group 7 decreases intestinal polyposis and colon tumorigenesis in Apc(Min/+) mice
    • 1:CAS:528:DC%2BC3sXmvVShtb0%3D 23361301 3643996
    • Xu C, Reichert EC, Nakano T, Lohse M, Gardner AA, Revelo MP, et al. Deficiency of phospholipase A2 group 7 decreases intestinal polyposis and colon tumorigenesis in Apc(Min/+) mice. Cancer Res. 2013;73:2806-16.
    • (2013) Cancer Res , vol.73 , pp. 2806-2816
    • Xu, C.1    Reichert, E.C.2    Nakano, T.3    Lohse, M.4    Gardner, A.A.5    Revelo, M.P.6
  • 75
    • 84907451363 scopus 로고    scopus 로고
    • Silencing of CXCR7 gene represses growth and invasion and induces apoptosis in colorectal cancer through ERK and β-arrestin pathways
    • 1:CAS:528:DC%2BC2cXhvFyit7rF 25051350
    • Li XX, Zheng HT, Huang LY, Shi DB, Peng JJ, Liang L, et al. Silencing of CXCR7 gene represses growth and invasion and induces apoptosis in colorectal cancer through ERK and β-arrestin pathways. Int J Oncol. 2014;45:1649-57.
    • (2014) Int J Oncol , vol.45 , pp. 1649-1657
    • Li, X.X.1    Zheng, H.T.2    Huang, L.Y.3    Shi, D.B.4    Peng, J.J.5    Liang, L.6
  • 76
    • 84874051340 scopus 로고    scopus 로고
    • Expression of β-arrestin 1 in gastric cardiac adenocarcinoma and its relation with progression
    • 23317236
    • Wang LG, Su BH, Du JJ. Expression of β-arrestin 1 in gastric cardiac adenocarcinoma and its relation with progression. Asian Pac J Cancer Prev. 2012;13:5671-5.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 5671-5675
    • Wang, L.G.1    Su, B.H.2    Du, J.J.3
  • 77
    • 84907885805 scopus 로고    scopus 로고
    • Knockdown of CXCR7 inhibits proliferation and invasion of osteosarcoma cells through inhibition of the PI3K/Akt and β-arrestin pathways
    • 24969680
    • Zhang Y, Yang CQ, Gao Y, Wang C, Zhang CL, Zhou XH. Knockdown of CXCR7 inhibits proliferation and invasion of osteosarcoma cells through inhibition of the PI3K/Akt and β-arrestin pathways. Oncol Rep. 2014;32:965-72.
    • (2014) Oncol Rep , vol.32 , pp. 965-972
    • Zhang, Y.1    Yang, C.Q.2    Gao, Y.3    Wang, C.4    Zhang, C.L.5    Zhou, X.H.6
  • 78
    • 84939890969 scopus 로고    scopus 로고
    • CXCL12-γ in primary tumors drives breast cancer metastasis
    • 1:CAS:528:DC%2BC2cXpsVamtLc%3D 24909174
    • Ray P, Stacer AC, Fenner J, Cavnar SP, Meguiar K, Brown M, et al. CXCL12-γ in primary tumors drives breast cancer metastasis. Oncogene. 2015;34:2043-51.
    • (2015) Oncogene , vol.34 , pp. 2043-2051
    • Ray, P.1    Stacer, A.C.2    Fenner, J.3    Cavnar, S.P.4    Meguiar, K.5    Brown, M.6
  • 79
    • 84896528786 scopus 로고    scopus 로고
    • G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion
    • Feigin ME, Xue B, Hammell MC, Muthuswamy SK. G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion. Proc Natl Acad Sci. 2014;1(11):4191-6.
    • (2014) Proc Natl Acad Sci , vol.1 , Issue.11 , pp. 4191-4196
    • Feigin, M.E.1    Xue, B.2    Hammell, M.C.3    Muthuswamy, S.K.4
  • 80
    • 84873539187 scopus 로고    scopus 로고
    • β-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1
    • 1:CAS:528:DC%2BC3sXivFKjsLY%3D 23405264 3566084
    • Alemayehu M, Dragan M, Pape C, Siddiqui I, Sacks DB, Di Guglielmo GM, et al. β-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1. PLoS One. 2013;8:e56174.
    • (2013) PLoS One , vol.8 , pp. e56174
    • Alemayehu, M.1    Dragan, M.2    Pape, C.3    Siddiqui, I.4    Sacks, D.B.5    Di Guglielmo, G.M.6
  • 81
    • 79959610178 scopus 로고    scopus 로고
    • GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness
    • 1:CAS:528:DC%2BC3MXosVaitb4%3D 21738726 3125256
    • Zajac M, Law J, Cvetkovic DD, Pampillo M, McColl L, Pape C, et al. GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness. PLoS One. 2011;6, e21599.
    • (2011) PLoS One , vol.6 , pp. e21599
    • Zajac, M.1    Law, J.2    Cvetkovic, D.D.3    Pampillo, M.4    McColl, L.5    Pape, C.6
  • 82
    • 79955009165 scopus 로고    scopus 로고
    • Stromal expression of β-arrestin-1 predicts clinical outcome and tamoxifen response in breast cancer
    • 1:CAS:528:DC%2BC3MXntlyisrc%3D 21497294 3077729
    • Lundgren K, Tobin NP, Lehn S, Stål O, Rydén L, et al. Stromal expression of β-arrestin-1 predicts clinical outcome and tamoxifen response in breast cancer. J Mol Diagn. 2011;13:340-51.
    • (2011) J Mol Diagn , vol.13 , pp. 340-351
    • Lundgren, K.1    Tobin, N.P.2    Lehn, S.3    Stål, O.4    Rydén, L.5
  • 83
    • 67651151233 scopus 로고    scopus 로고
    • Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells
    • 1:CAS:528:DC%2BD1MXos1emtrs%3D 19609003
    • Li TT, Alemayehu M, Aziziyeh AI, Pape C, Pampillo M, Postovit LM, et al. Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells. Mol Cancer Res. 2009;7:1064-77.
    • (2009) Mol Cancer Res , vol.7 , pp. 1064-1077
    • Li, T.T.1    Alemayehu, M.2    Aziziyeh, A.I.3    Pape, C.4    Pampillo, M.5    Postovit, L.M.6
  • 84
    • 65649113637 scopus 로고    scopus 로고
    • Beta-arrestin2 inhibits opioid-induced breast cancer cell death through Akt and caspase-8 pathways
    • 1:CAS:528:DC%2BD1MXjs12qt7Y%3D 19239323
    • Zhao M, Zhou G, Zhang Y, Chen T, Sun X, Stuart C, et al. beta-arrestin2 inhibits opioid-induced breast cancer cell death through Akt and caspase-8 pathways. Neoplasma. 2009;56:108-13.
    • (2009) Neoplasma , vol.56 , pp. 108-113
    • Zhao, M.1    Zhou, G.2    Zhang, Y.3    Chen, T.4    Sun, X.5    Stuart, C.6
  • 85
    • 11244255416 scopus 로고    scopus 로고
    • Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2
    • 1:CAS:528:DC%2BD2cXhtFeis7vN 15489220
    • Ge L, Shenoy SK, Lefkowitz RJ, DeFea K. Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2. J Biol Chem. 2004;279:55419-24.
    • (2004) J Biol Chem , vol.279 , pp. 55419-55424
    • Ge, L.1    Shenoy, S.K.2    Lefkowitz, R.J.3    DeFea, K.4
  • 86
    • 0037147145 scopus 로고    scopus 로고
    • Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
    • 1:CAS:528:DC%2BD38XpsFaluro%3D 12370187
    • Sun Y, Cheng Z, Ma L, Pei G. Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J Biol Chem. 2002;277:49212-9.
    • (2002) J Biol Chem , vol.277 , pp. 49212-49219
    • Sun, Y.1    Cheng, Z.2    Ma, L.3    Pei, G.4
  • 87
    • 84896808624 scopus 로고    scopus 로고
    • β-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma
    • 24452472 4170118
    • Clift IC, Bamidele AO, Rodriguez-Ramirez C, Kremer KN, Hedin KE. β-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma. Mol Pharmacol. 2014;85:542-52.
    • (2014) Mol Pharmacol , vol.85 , pp. 542-552
    • Clift, I.C.1    Bamidele, A.O.2    Rodriguez-Ramirez, C.3    Kremer, K.N.4    Hedin, K.E.5
  • 88
    • 84874417600 scopus 로고    scopus 로고
    • β-Arrestin-biased agonism as the central mechanism of action for insulin-like growth factor 1 receptor-targeting antibodies in Ewing's sarcoma
    • 1:CAS:528:DC%2BC3sXnvVSqug%3D%3D 23188799 3528604
    • Zheng H, Shen H, Oprea I, Worrall C, Stefanescu R, Girnita A, et al. β-Arrestin-biased agonism as the central mechanism of action for insulin-like growth factor 1 receptor-targeting antibodies in Ewing's sarcoma. Proc Natl Acad Sci. 2012;109:20620-5.
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 20620-20625
    • Zheng, H.1    Shen, H.2    Oprea, I.3    Worrall, C.4    Stefanescu, R.5    Girnita, A.6
  • 89
    • 84883164592 scopus 로고    scopus 로고
    • Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells
    • 1:CAS:528:DC%2BC3sXjtlynsr0%3D 22965194
    • Spinella F, Caprara V, Di Castro V, Rosanò L, Cianfrocca R, Natali PG, et al. Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells. J Mol Med. 2013;91:395-405.
    • (2013) J Mol Med , vol.91 , pp. 395-405
    • Spinella, F.1    Caprara, V.2    Di Castro, V.3    Rosanò, L.4    Cianfrocca, R.5    Natali, P.G.6
  • 90
    • 84859136834 scopus 로고    scopus 로고
    • Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells
    • 1:CAS:528:DC%2BC38XosVelsLs%3D 22472349 3342892
    • Heinrich EL, Lee W, Lu J, Lowy AM, Kim J. Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells. J Transl Med. 2012;10:68.
    • (2012) J Transl Med , vol.10 , pp. 68
    • Heinrich, E.L.1    Lee, W.2    Lu, J.3    Lowy, A.M.4    Kim, J.5


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