Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells

Oncogene

Volumn 33, Issue 13, 2014, Pages 1725-1735

  Wu, M H ^a   Huang, C Y ^a,b   Lin, J A ^a   Wang, S W ^c   Peng, C Y ^a,d   Cheng, H C ^e   Tang, C H ^a,f,g  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b ASIA UNIVERSITY   (Taiwan)

^c MACKAY MEDICAL COLLEGE   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^f CHINA MEDICAL UNIVERSITY   (Taiwan)

^g ASIA UNIVERSITY   (Taiwan)

Author keywords

Angiogenesis; Chondrosarcoma; ET 1; VEGF

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTEGRIN LINKED KINASE; MATRIGEL; PROTEIN KINASE B; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER STAGING; CARTILAGE; CELL MIGRATION; CHICK; CHONDROSARCOMA; CHORIOALLANTOIS; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIAL PROGENITOR CELL; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOMA CELL; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR XENOGRAFT;

MUS MUSCULUS;

ANIMALS; BONE NEOPLASMS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CHICK EMBRYO; CHONDROSARCOMA; ENDOTHELIN-1; GENE KNOCKDOWN TECHNIQUES; HETEROGRAFTS; HUMANS; MALE; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84898016402     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.109     Document Type: Article

References (41)

1. Terek RM, Schwartz GK, Devaney K, Glantz L, Mak S, Healey JH, et al. Chemotherapy and P-glycoprotein expression in chondrosarcoma. J Orthop Res 1998; 16: 585-590
2. Bishayee A, Darvesh AS. Angiogenesis in hepatocellular carcinoma: A potential target for chemoprevention and therapy. Curr Cancer Drug Targets 2012; 12: 1095-1118
3. Albini A, Tosetti F, Li VW, Noonan DM, Li WW. Cancer prevention by targeting angiogenesis. Nat Rev Clin Oncol 2012; 9: 498-509
4. Weis SM, Cheresh DA. Tumor angiogenesis: Molecular pathways and therapeutic targets. Nat Med 2011; 17: 1359-1370
5. Keating AM, Jacobs DS. Anti-VEGF treatment of corneal neovascularization. Ocul Surf 2011; 9: 227-237
6. Herrmann E, Bogemann M, Bierer S, Eltze E, Hertle L, Wulfing C. The endothelin axis in urologic tumors: Mechanisms of tumor biology and therapeutic implications. Expert Rev Anticancer Ther 2006; 6: 73-81
7. Wulfing P, Kersting C, Tio J, Fischer RJ, Wulfing C, Poremba C, et al. Endothelin-1-, endothelin-A-, and endothelin-B-receptor expression is correlated with vascular endothelial growth factor expression and angiogenesis in breast cancer. Clin Cancer Res 2004; 10: 2393-2400
8. Lahav R, Suva ML, Rimoldi D, Patterson PH, Stamenkovic I. Endothelin receptor B inhibition triggers apoptosis and enhances angiogenesis in melanomas. Cancer Res 2004; 64: 8945-8953
9. Lamagna C, Aurrand-Lions M, Imhof BA. Dual role of macrophages in tumor growth and angiogenesis. J Leukocyte Biol 2006; 80: 705-713
10. Spinella F, Rosano L, Del Duca M, Di Castro V, Nicotra MR, Natali PG, et al. Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells. PLoS One 2010; 5: E11241
11. Boldrini L, Pistolesi S, Gisfredi S, Ursino S, Ali G, Pieracci N, et al. Expression of endothelin 1 and its angiogenic role in meningiomas. Virchows Archiv 2006; 449: 546-553
12. Zhou WQ, Yin HL, Zhang ZY, Yi XM, Ge JP, Zhou SG, et al. [Expression of VEGF in prostate cancer and its correlation with ET-1]. Natl J Androl 2008; 14: 987-992
13. Wu MH, Lo JF, Kuo CH, Lin JA, Lin YM, Chen LM, et al. Endothelin-1 promotes MMP-13 production and migration in human chondrosarcoma cells through FAK/ PI3K/Akt/mTOR pathways. J Cell Physiol 2012; 227: 3016-3026
14. Venuti A, Salani D, Cirilli A, Simeone P, Muller A, et al. Endothelin receptor blockade inhibits the growth of human papillomavirus-Associated cervical carcinoma. Clin Sci (Lond) 2002; 103(Suppl 48): 310S-313SS
15. Nagy JA, Dvorak AM, Dvorak HF. VEGF-A and the induction of pathological angiogenesis. Annu Rev Pathol 2007; 2: 251-275
16. Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003; 3: 401-410
17. Villers A, Neuzillet Y, Beuzeboc P. Inhibitors of the receptor A for endothelin-1. Progr Urol 2010; 20(Suppl 1): S77-S79
18. Merino M, Pinto A, Gonzalez R, Espinosa E. Antiangiogenic agents and endothelin antagonists in advanced castration resistant prostate cancer. Eur J Cancer 2011; 47: 1846-1851
19. Kaneko Y, Kitazato K, Basaki Y. Integrin-linked kinase regulates vascular morphogenesis induced by vascular endothelial growth factor. J Cell Sci 2004; 117(Part 3): 407-415
20. Camenisch G, Stroka DM, Gassmann M, Wenger RH. Attenuation of HIF-1 DNAbinding activity limits hypoxia-inducible endothelin-1 expression. Pflugers Arch 2001; 443: 240-249
21. Whitman EM, Pisarcik S, Luke T, Fallon M, Wang J, Sylvester JT, et al. Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K. channel expression in pulmonary arterial myocytes. Am J Physiol Lung Cell Mol Physiol 2008; 294: L309-L318
22. Yen ML, Su JL, Chien CL, Tseng KW, Yang CY, Chen WF, et al. Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor- related phosphatidylinositol 3-kinase/Akt and p38 mitogen-Activated protein kinase pathways in osteoblasts. Mol Pharmacol 2005; 68: 1061-1073
23. Bagnato A, Spinella F, Rosano L. The endothelin axis in cancer: The promise and the challenges of molecularly targeted therapy. Canad J Physiol Pharmacol 2008; 86: 473-484
24. Demunter A, De Wolf-Peeters C, Degreef H, Stas M, Van Den Oord JJ. Expression of the endothelin-B receptor in pigment cell lesions of the skin. Evidence for its role as tumor progression marker in malignant melanoma. Virchows Archiv 2001; 438: 485-491.
25. Spinella F, Rosano L, Di Castro V, Natali PG, Bagnato A. Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion. J Biol Chem 2004; 279: 46700-46705
26. Bagnato A, Spinella F. Emerging role of endothelin-1 in tumor angiogenesis. Trends Endocrinol Metab 2003; 14: 44-50
27. Lahav R, Heffner G, Patterson PH. An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo. Proc Natl Acad Sci USA 1999; 96: 11496-11500
28. Zhang H, Han Y, Tao J, Liu S, Yan C, Li S. Cellular repressor of E1A-stimulated genes regulates vascular endothelial cell migration by the ILK/AKT/mTOR/ VEGF(165) signaling pathway. Exp Cell Res 2011; 317: 2904-2913
29. Tseng WP, Yang SN, Lai CH, Tang CH. Hypoxia induces BMP-2 expression via ILK, Akt, mTOR, and HIF-1 pathways in osteoblasts. J Cell Physiol 2010; 223: 810-818
30. Rosano L, Spinella F, Di Castro V, Dedhar S, Nicotra MR, Natali PG, et al. Integrinlinked kinase functions as a downstream mediator of endothelin-1 to promote invasive behavior in ovarian carcinoma. Mol Cancer Therap 2006; 5: 833-842
31. Cianfrocca R, Rosano L, Spinella F, Di Castro V, Natali PG, Bagnato A. Beta-Arrestin- 1 mediates the endothelin-1-induced activation of Akt and integrin-linked kinase. Canad J Physiol Pharmacol 2010; 88: 796-801
32. Wang HH, Lin CA, Lee CH, Lin YC, Tseng YM, Hsieh CL, et al. Fluorescent gold nanoclusters as a biocompatible marker for in vitro and in vivo tracking of endothelial cells. ACS Nano 2011; 5: 4337-4344
33. Hsieh MT, Hsieh CL, Lin LW, Wu CR, Huang GS. Differential gene expression of scopolamine-Treated rat hippocampus-Application of cDNA microarray technology. Life Sci 2003; 73: 1007-1016
34. Wang YC, Lee PJ, Shih CM, Chen HY, Lee CC, Chang YY, et al. Damage formation and repair efficiency in the p53 gene of cell lines and blood lymphocytes assayed by multiplex long quantitative polymerase chain reaction. Anal Biochem 2003; 319: 206-215
35. Huang HC, Shi GY, Jiang SJ, Shi CS, Wu CM, Yang HY, et al. Thrombomodulinmediated cell adhesion: Involvement of its lectin-like domain. J Biol Chem 2003; 278: 46750-46759
36. Tseng CP, Huang CL, Huang CH, Cheng JC, Stern A, Tseng CH, et al. Disabled-2 small interfering RNA modulates cellular adhesive function and MAPK activity during megakaryocytic differentiation of K562 cells. FEBS Lett 2003; 541: 21-27
37. Tang CH, Lu DY, Tan TW, Fu WM, Yang RS. Ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target of rapamycin pathway in osteoblasts. J Biol Chem 2007; 282: 25406-25415
38. Xia X, Lemieux ME, Li W, Carroll JS, Brown M, Liu XS, et al. Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc Natl Acad Sci USA 2009; 106: 4260-4265
39. Nickols NG, Jacobs CS, Farkas ME, Dervan PB. Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface. ACS Chem Biol 2007; 2: 561-571
40. Storgard C, Mikolon D, Stupack DG. Angiogenesis assays in the chick CAM. Methods Mol Biol 2005; 294: 123-136
41. Passaniti A, Taylor RM, Pili R, Guo Y, Long PV, Haney JA, et al. A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor. Lab Invest 1992; 67: 519-528.