β-arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma

Molecular Pharmacology

Volumn 85, Issue 4, 2014, Pages 542-552

  Clift, Ian C ^a   Bamidele, Adebowale O ^b   Rodriguez Ramirez, Christie ^a   Kremer, Kimberly N ^a   Hedin, Karen E ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN 1; CHEMOKINE RECEPTOR CXCR4; G PROTEIN COUPLED RECEPTOR KINASE 2; MUTANT PROTEIN; PROTEIN KINASE C; SERINE DERIVATIVE; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; CANCER PROGNOSIS; CELL PROLIFERATION; CELL SURFACE; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INTERNALIZATION; NEUROBLASTOMA CELL; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN STRUCTURE; RECEPTOR DOWN REGULATION; TUMOR GROWTH;

ARRESTINS; CELL LINE, TUMOR; CELL MEMBRANE; CHEMOKINE CXCL12; ENDOCYTOSIS; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GTP-BINDING PROTEINS; HUMANS; NEOPLASM METASTASIS; NEUROBLASTOMA; PERTUSSIS TOXIN; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTORS, CXCR4; TETRADECANOYLPHORBOL ACETATE; TYPE C PHOSPHOLIPASES;

EID: 84896808624     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.113.089714     Document Type: Article

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