메뉴 건너뛰기




Volumn 36, Issue 8, 2015, Pages 6551-6558

Co-expression of β-arrestin1 and NF-кB is associated with cancer progression and poor prognosis in lung adenocarcinoma

Author keywords

Lung adenocarcinoma; NF B; p65; Prognosis; arrestin1

Indexed keywords

BETA ARRESTIN 1; TRANSCRIPTION FACTOR RELA; BETA ARRESTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RETINA S ANTIGEN; TUMOR MARKER;

EID: 84940435107     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3349-7     Document Type: Article
Times cited : (19)

References (42)
  • 2
    • 33749652386 scopus 로고    scopus 로고
    • Emerging roles of beta-arrestins
    • COI: 1:CAS:528:DC%2BD28XhtlGqsr%2FL, PID: 16969081
    • Buchanan FG, DuBois RN. Emerging roles of beta-arrestins. Cell Cycle. 2006;5:2060–3.
    • (2006) Cell Cycle , vol.5 , pp. 2060-2063
    • Buchanan, F.G.1    DuBois, R.N.2
  • 3
    • 28344452845 scopus 로고    scopus 로고
    • A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription
    • COI: 1:CAS:528:DC%2BD2MXhtlWntLjE, PID: 16325578
    • Kang J, Shi Y, Xiang B, Qu B, Su W, Zhu M, et al. A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription. Cell. 2005;123:833–47.
    • (2005) Cell , vol.123 , pp. 833-847
    • Kang, J.1    Shi, Y.2    Xiang, B.3    Qu, B.4    Su, W.5    Zhu, M.6
  • 4
    • 0037020264 scopus 로고    scopus 로고
    • Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2
    • COI: 1:CAS:528:DC%2BD38XnsVejtr8%3D, PID: 12167659
    • Scott MG, Le Rouzic E, Perianin A, Pierotti V, Enslen H, Benichou S, et al. Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2. J Biol Chem. 2002;277:37693–701.
    • (2002) J Biol Chem , vol.277 , pp. 37693-37701
    • Scott, M.G.1    Le Rouzic, E.2    Perianin, A.3    Pierotti, V.4    Enslen, H.5    Benichou, S.6
  • 5
    • 0038514264 scopus 로고    scopus 로고
    • Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus
    • COI: 1:CAS:528:DC%2BD3sXit1Kgtbc%3D, PID: 12538596
    • Wang P, Wu Y, Ge X, Ma L, Pei G. Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus. J Biol Chem. 2003;278:11648–53.
    • (2003) J Biol Chem , vol.278 , pp. 11648-11653
    • Wang, P.1    Wu, Y.2    Ge, X.3    Ma, L.4    Pei, G.5
  • 6
    • 34547512353 scopus 로고    scopus 로고
    • Functional specialization of beta-arrestin interactions revealed by proteomic analysis
    • COI: 1:CAS:528:DC%2BD2sXosVClsbc%3D, PID: 17620599
    • Xiao K, McClatchy DB, Shukla AK, Zhao Y, Chen M, Shenoy SK, et al. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Proc Natl Acad Sci U S A. 2007;104:12011–6.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12011-12016
    • Xiao, K.1    McClatchy, D.B.2    Shukla, A.K.3    Zhao, Y.4    Chen, M.5    Shenoy, S.K.6
  • 7
    • 33846998992 scopus 로고    scopus 로고
    • Beta-arrestin signaling and regulation of transcription
    • COI: 1:CAS:528:DC%2BD2sXhvFGmsr0%3D, PID: 17215450
    • Ma L, Pei G. Beta-arrestin signaling and regulation of transcription. J Cell Sci. 2007;120:213–8.
    • (2007) J Cell Sci , vol.120 , pp. 213-218
    • Ma, L.1    Pei, G.2
  • 8
    • 77958457960 scopus 로고    scopus 로고
    • Beta-arrestin-1 links mitogenic sonic hedgehog signaling to the cell cycle exit machinery in neural precursors
    • COI: 1:CAS:528:DC%2BC3MXhsVentL0%3D, PID: 20935513
    • Parathath SR, Mainwaring LA, Fernandez LA, Guldal CG, Nahle Z, Kenney AM. Beta-arrestin-1 links mitogenic sonic hedgehog signaling to the cell cycle exit machinery in neural precursors. Cell Cycle. 2010;9:4013–24.
    • (2010) Cell Cycle , vol.9 , pp. 4013-4024
    • Parathath, S.R.1    Mainwaring, L.A.2    Fernandez, L.A.3    Guldal, C.G.4    Nahle, Z.5    Kenney, A.M.6
  • 9
    • 70350376890 scopus 로고    scopus 로고
    • Beta-arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression
    • COI: 1:CAS:528:DC%2BD1MXhsFKltLzN, PID: 19879840
    • Yue R, Kang J, Zhao C, Hu W, Tang Y, Liu X, et al. Beta-arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression. Cell. 2009;139:535–46.
    • (2009) Cell , vol.139 , pp. 535-546
    • Yue, R.1    Kang, J.2    Zhao, C.3    Hu, W.4    Tang, Y.5    Liu, X.6
  • 11
    • 84855927182 scopus 로고    scopus 로고
    • Beta-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression
    • COI: 1:CAS:528:DC%2BC3MXnslSmurk%3D, PID: 21685944
    • Shenoy SK, Han S, Zhao YL, Hara MR, Oliver T, Cao Y, et al. Beta-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression. Oncogene. 2012;31:282–92.
    • (2012) Oncogene , vol.31 , pp. 282-292
    • Shenoy, S.K.1    Han, S.2    Zhao, Y.L.3    Hara, M.R.4    Oliver, T.5    Cao, Y.6
  • 12
    • 84903288729 scopus 로고    scopus 로고
    • Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer
    • COI: 1:CAS:528:DC%2BC2cXhtlKnu7zE, PID: 24837709
    • Zecchini V, Madhu B, Russell R, Pertega-Gomes N, Warren A, Gaude E, et al. Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer. EMBO J. 2014;33:1365–82.
    • (2014) EMBO J , vol.33 , pp. 1365-1382
    • Zecchini, V.1    Madhu, B.2    Russell, R.3    Pertega-Gomes, N.4    Warren, A.5    Gaude, E.6
  • 13
    • 79951923011 scopus 로고    scopus 로고
    • ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors
    • COI: 1:CAS:528:DC%2BC3MXitlejsLw%3D, PID: 21212384
    • Dasgupta P, Rizwani W, Pillai S, Davis R, Banerjee S, Hug K, et al. ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors. J Natl Cancer Inst. 2011;103:317–33.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 317-333
    • Dasgupta, P.1    Rizwani, W.2    Pillai, S.3    Davis, R.4    Banerjee, S.5    Hug, K.6
  • 14
    • 2942554958 scopus 로고    scopus 로고
    • Beta-arrestin inhibits NF-kappa B activity by means of its interaction with the NF-kappa B inhibitor I kappa B alpha
    • COI: 1:CAS:528:DC%2BD2cXltFKks70%3D, PID: 15173580
    • Witherow DS, Garrison TR, Miller WE, Lefkowitz RJ. Beta-arrestin inhibits NF-kappa B activity by means of its interaction with the NF-kappa B inhibitor I kappa B alpha. Proc Natl Acad Sci U S A. 2004;101:8603–7.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8603-8607
    • Witherow, D.S.1    Garrison, T.R.2    Miller, W.E.3    Lefkowitz, R.J.4
  • 15
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: the enemy within
    • COI: 1:CAS:528:DC%2BD2cXot1Kis78%3D, PID: 15380510
    • Aggarwal BB. Nuclear factor-kappaB: the enemy within. Cancer Cell. 2004;6:203–8.
    • (2004) Cancer Cell , vol.6 , pp. 203-208
    • Aggarwal, B.B.1
  • 16
    • 0037044575 scopus 로고    scopus 로고
    • The I kappa B-NF-kappa B signaling module: temporal control and selective gene activation
    • COI: 1:CAS:528:DC%2BD38XosVerurc%3D, PID: 12424381
    • Hoffmann A, Levchenko A, Scott ML, Baltimore D. The I kappa B-NF-kappa B signaling module: temporal control and selective gene activation. Science. 2002;298:1241–5.
    • (2002) Science , vol.298 , pp. 1241-1245
    • Hoffmann, A.1    Levchenko, A.2    Scott, M.L.3    Baltimore, D.4
  • 17
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
    • COI: 1:CAS:528:DyaK1cXislygtL0%3D, PID: 9597130
    • Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol. 1998;16:225–60.
    • (1998) Annu Rev Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 18
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: from innocent bystander to major culprit
    • COI: 1:CAS:528:DC%2BD38XivFGqt7k%3D, PID: 12001991
    • Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer. 2002;2:301–10.
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 19
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-kappa B system: a treasure trove for drug development
    • COI: 1:CAS:528:DC%2BD2cXpvFKqug%3D%3D, PID: 14708018
    • Karin M, Yamamoto Y, Wang QM. The IKK NF-kappa B system: a treasure trove for drug development. Nat Rev Drug Discov. 2004;3:17–26.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 20
    • 77951035570 scopus 로고    scopus 로고
    • NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer
    • COI: 1:CAS:528:DC%2BC3cXotFems7o%3D, PID: 20414006
    • Puvvada SD, Funkhouser WK, Greene K, Deal A, Chu H, Baldwin AS, et al. NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer. Oncology. 2010;78:181–8.
    • (2010) Oncology , vol.78 , pp. 181-188
    • Puvvada, S.D.1    Funkhouser, W.K.2    Greene, K.3    Deal, A.4    Chu, H.5    Baldwin, A.S.6
  • 21
    • 0035964203 scopus 로고    scopus 로고
    • The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers
    • COI: 1:CAS:528:DC%2BD3MXmvFWiu7c%3D, PID: 11517301
    • Biswas DK, Dai SC, Cruz A, Weiser B, Graner E, Pardee AB. The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers. Proc Natl Acad Sci U S A. 2001;98:10386–91.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10386-10391
    • Biswas, D.K.1    Dai, S.C.2    Cruz, A.3    Weiser, B.4    Graner, E.5    Pardee, A.B.6
  • 22
    • 16644397046 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate
    • COI: 1:CAS:528:DC%2BD2cXmvFSltbw%3D
    • Sweeney C, Li L, Shanmugam R, Bhat-Nakshatri P, Jayaprakasan V, Baldridge LA, et al. Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate. Clin Cancer Res: Off J Am Assoc Cancer Res. 2004;10:5501–7.
    • (2004) Clin Cancer Res: Off J Am Assoc Cancer Res , vol.10 , pp. 5501-5507
    • Sweeney, C.1    Li, L.2    Shanmugam, R.3    Bhat-Nakshatri, P.4    Jayaprakasan, V.5    Baldridge, L.A.6
  • 23
    • 34547865350 scopus 로고    scopus 로고
    • High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis
    • COI: 1:CAS:528:DC%2BD2sXptVWjurY%3D, PID: 17622249
    • Weichert W, Boehm M, Gekeler V, Bahra M, Langrehr J, Neuhaus P, et al. High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis. Br J Cancer. 2007;97:523–30.
    • (2007) Br J Cancer , vol.97 , pp. 523-530
    • Weichert, W.1    Boehm, M.2    Gekeler, V.3    Bahra, M.4    Langrehr, J.5    Neuhaus, P.6
  • 24
    • 33751570051 scopus 로고    scopus 로고
    • Wistuba, II: nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions
    • COI: 1:CAS:528:DC%2BD28XhtlCmu7nO, PID: 17078054
    • Tang X, Liu D, Shishodia S, Ozburn N, Behrens C, Lee JJ, et al. Wistuba, II: nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions. Cancer. 2006;107:2637–46.
    • (2006) Cancer , vol.107 , pp. 2637-2646
    • Tang, X.1    Liu, D.2    Shishodia, S.3    Ozburn, N.4    Behrens, C.5    Lee, J.J.6
  • 25
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappa B in cancer development and progression
    • COI: 1:CAS:528:DC%2BD28XkvVyrsrw%3D, PID: 16724054
    • Karin M. Nuclear factor-kappa B in cancer development and progression. Nature. 2006;441:431–6.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 26
    • 25844459154 scopus 로고    scopus 로고
    • Nf-kappab: linking inflammation and immunity to cancer development and progression
    • COI: 1:CAS:528:DC%2BD2MXhtVGrurvL, PID: 16175180
    • Karin M, Greten FR. Nf-kappab: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol. 2005;5:749–59.
    • (2005) Nat Rev Immunol , vol.5 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 27
    • 4644324186 scopus 로고    scopus 로고
    • NF-kappaB functions as a tumour promoter in inflammation-associated cancer
    • COI: 1:CAS:528:DC%2BD2cXnslelsrc%3D, PID: 15329734
    • Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature. 2004;431:461–6.
    • (2004) Nature , vol.431 , pp. 461-466
    • Pikarsky, E.1    Porat, R.M.2    Stein, I.3    Abramovitch, R.4    Amit, S.5    Kasem, S.6
  • 28
    • 84858612683 scopus 로고    scopus 로고
    • Identification of a nuclear localization sequence in beta-arrestin-1 and its functional implications
    • COI: 1:CAS:528:DC%2BC38XjvVehtbY%3D, PID: 22267743
    • Hoeppner CZ, Cheng N, Ye RD. Identification of a nuclear localization sequence in beta-arrestin-1 and its functional implications. J Biol Chem. 2012;287:8932–43.
    • (2012) J Biol Chem , vol.287 , pp. 8932-8943
    • Hoeppner, C.Z.1    Cheng, N.2    Ye, R.D.3
  • 29
    • 58249088830 scopus 로고    scopus 로고
    • Beta-arrestin1 interacts with the G-protein subunits beta(1)gamma(2) and promotes beta(1)gamma(2)-dependent Akt signalling for NF-kappa B activation
    • COI: 1:CAS:528:DC%2BD1cXhsV2lt73K, PID: 18729826
    • Yang M, He RL, Benovic JL, Ye RD. Beta-arrestin1 interacts with the G-protein subunits beta(1)gamma(2) and promotes beta(1)gamma(2)-dependent Akt signalling for NF-kappa B activation. Biochem J. 2009;417:287–96.
    • (2009) Biochem J , vol.417 , pp. 287-296
    • Yang, M.1    He, R.L.2    Benovic, J.L.3    Ye, R.D.4
  • 30
    • 0041341922 scopus 로고    scopus 로고
    • Requirement of Gbetagamma and c-Src in D2 dopamine receptor-mediated nuclear factor-kappaB activation
    • COI: 1:CAS:528:DC%2BD3sXlvVCnsLo%3D, PID: 12869650
    • Yang M, Zhang H, Voyno-Yasenetskaya T, Ye RD. Requirement of Gbetagamma and c-Src in D2 dopamine receptor-mediated nuclear factor-kappaB activation. Mol Pharmacol. 2003;64:447–55.
    • (2003) Mol Pharmacol , vol.64 , pp. 447-455
    • Yang, M.1    Zhang, H.2    Voyno-Yasenetskaya, T.3    Ye, R.D.4
  • 32
    • 77954818058 scopus 로고    scopus 로고
    • The American joint committee on cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM
    • PID: 20180029
    • Edge SB, Compton CC. The American joint committee on cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol. 2010;17:1471–4.
    • (2010) Ann Surg Oncol , vol.17 , pp. 1471-1474
    • Edge, S.B.1    Compton, C.C.2
  • 33
    • 84879083783 scopus 로고    scopus 로고
    • The role of beta-arrestins in cancer
    • COI: 1:CAS:528:DC%2BC3sXhsFegsLnI, PID: 23764062
    • Sobolesky PM, Moussa O. The role of beta-arrestins in cancer. Prog Mol Biol Transl Sci. 2013;118:395–411.
    • (2013) Prog Mol Biol Transl Sci , vol.118 , pp. 395-411
    • Sobolesky, P.M.1    Moussa, O.2
  • 34
    • 84886100276 scopus 로고    scopus 로고
    • Beta-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced beta-catenin signaling
    • COI: 1:CAS:528:DC%2BC38XhslKmtLnP, PID: 23208497
    • Rosano L, Cianfrocca R, Tocci P, Spinella F, Di Castro V, Spadaro F, et al. Beta-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced beta-catenin signaling. Oncogene. 2013;32:5066–77.
    • (2013) Oncogene , vol.32 , pp. 5066-5077
    • Rosano, L.1    Cianfrocca, R.2    Tocci, P.3    Spinella, F.4    Di Castro, V.5    Spadaro, F.6
  • 35
    • 43049109478 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation and differential expression of survivin and Bcl-2 in human grade 2-4 astrocytomas
    • COI: 1:CAS:528:DC%2BD1cXmt1CnsL4%3D, PID: 18327814
    • Angileri FF, Aguennouz M, Conti A, La Torre D, Cardali S, Crupi R, et al. Nuclear factor-kappaB activation and differential expression of survivin and Bcl-2 in human grade 2-4 astrocytomas. Cancer. 2008;112:2258–66.
    • (2008) Cancer , vol.112 , pp. 2258-2266
    • Angileri, F.F.1    Aguennouz, M.2    Conti, A.3    La Torre, D.4    Cardali, S.5    Crupi, R.6
  • 36
    • 84901506299 scopus 로고    scopus 로고
    • Expression of the antimicrobial peptide cathelicidin in myeloid cells is required for lung tumor growth
    • COI: 1:CAS:528:DC%2BC3sXhtVaktLzJ, PID: 23812430
    • Li D, Beisswenger C, Herr C, Schmid RM, Gallo RL, Han G, et al. Expression of the antimicrobial peptide cathelicidin in myeloid cells is required for lung tumor growth. Oncogene. 2014;33:2709–16.
    • (2014) Oncogene , vol.33 , pp. 2709-2716
    • Li, D.1    Beisswenger, C.2    Herr, C.3    Schmid, R.M.4    Gallo, R.L.5    Han, G.6
  • 38
    • 84892841683 scopus 로고    scopus 로고
    • Nf-kappaB protein expression associates with (18)F-FDG pet tumor uptake in non-small cell lung cancer: a radiogenomics validation study to understand tumor metabolism
    • PID: 24355259
    • Nair VS, Gevaert O, Davidzon G, Plevritis SK, West R. Nf-kappaB protein expression associates with (18)F-FDG pet tumor uptake in non-small cell lung cancer: a radiogenomics validation study to understand tumor metabolism. Lung Cancer. 2014;83:189–96.
    • (2014) Lung Cancer , vol.83 , pp. 189-196
    • Nair, V.S.1    Gevaert, O.2    Davidzon, G.3    Plevritis, S.K.4    West, R.5
  • 39
    • 77954297744 scopus 로고    scopus 로고
    • Nuclear factor kappa B transcription factors are coexpressed and convey a poor outcome in ovarian cancer
    • COI: 1:CAS:528:DC%2BC3cXptlWqu7k%3D, PID: 20564628
    • Annunziata CM, Stavnes HT, Kleinberg L, Berner A, Hernandez LF, Birrer MJ, et al. Nuclear factor kappa B transcription factors are coexpressed and convey a poor outcome in ovarian cancer. Cancer. 2010;116:3276–84.
    • (2010) Cancer , vol.116 , pp. 3276-3284
    • Annunziata, C.M.1    Stavnes, H.T.2    Kleinberg, L.3    Berner, A.4    Hernandez, L.F.5    Birrer, M.J.6
  • 40
    • 84880182986 scopus 로고    scopus 로고
    • Nuclear expression of glioma-associated oncogene homo log 1 and nuclear factor-kappa B is associated with a poor prognosis of pancreatic cancer
    • COI: 1:CAS:528:DC%2BC3sXhsVSit7fK, PID: 23860225
    • Yang S-H, Hsu C-H, Lee J-C, Tien Y-W, Kuo S-H, Cheng A-L. Nuclear expression of glioma-associated oncogene homo log 1 and nuclear factor-kappa B is associated with a poor prognosis of pancreatic cancer. Oncology. 2013;85:86–94.
    • (2013) Oncology , vol.85 , pp. 86-94
    • Yang, S.-H.1    Hsu, C.-H.2    Lee, J.-C.3    Tien, Y.-W.4    Kuo, S.-H.5    Cheng, A.-L.6
  • 41
    • 84868494287 scopus 로고    scopus 로고
    • Immunohistochemical study of nuclear factor-kappaB expression in esophageal squamous cell carcinoma: prognostic significance and sensitivity to treatment with 5-fu
    • COI: 1:STN:280:DC%2BC38vhs1amtg%3D%3D
    • Hatata T, Higaki K, Tatebe S, Shomori K, Ikeguchi M. Immunohistochemical study of nuclear factor-kappaB expression in esophageal squamous cell carcinoma: prognostic significance and sensitivity to treatment with 5-fu. Dis Esophagus: Off J Int Soc Dis Esophagus ISDE. 2012;25:716–22.
    • (2012) Dis Esophagus: Off J Int Soc Dis Esophagus ISDE , vol.25 , pp. 716-722
    • Hatata, T.1    Higaki, K.2    Tatebe, S.3    Shomori, K.4    Ikeguchi, M.5
  • 42


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.