-
1
-
-
84920837701
-
Cancer statistics, 2015
-
[1] Siegel, R.L., Miller, K.D., Jemal, A., Cancer statistics, 2015. CA Cancer J. Clin. 65 (2015), 5–29.
-
(2015)
CA Cancer J. Clin.
, vol.65
, pp. 5-29
-
-
Siegel, R.L.1
Miller, K.D.2
Jemal, A.3
-
2
-
-
84883153220
-
Endothelin 1 in cancer: biologicalimplications and therapeutic opportunities
-
[2] Rosanò, L., Spinella, F., Bagnato, A., Endothelin 1 in cancer: biologicalimplications and therapeutic opportunities. Nat. Rev. Cancer 9 (2013), 637–651.
-
(2013)
Nat. Rev. Cancer
, vol.9
, pp. 637-651
-
-
Rosanò, L.1
Spinella, F.2
Bagnato, A.3
-
3
-
-
0035890357
-
Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells
-
[3] Rosanò, L., Varmi, M., Salani, D., Di Castro, V., Spinella, F., Natali, P.G., Bagnato, A., Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells. Cancer Res. 61 (2001), 8340–8346.
-
(2001)
Cancer Res.
, vol.61
, pp. 8340-8346
-
-
Rosanò, L.1
Varmi, M.2
Salani, D.3
Di Castro, V.4
Spinella, F.5
Natali, P.G.6
Bagnato, A.7
-
4
-
-
78650957612
-
Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer
-
[4] Said, N., Smith, S., Sanchez-Carbayo, M., Theodorescu, D., Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer. J. Clin. Invest. 47 (2011), 132–147.
-
(2011)
J. Clin. Invest.
, vol.47
, pp. 132-147
-
-
Said, N.1
Smith, S.2
Sanchez-Carbayo, M.3
Theodorescu, D.4
-
5
-
-
84860441391
-
Endothelin-1 promotes MMP-13 production and migration in human chondrosarcoma cells through FAK/PI3K/Akt/mTOR pathways
-
[5] Wu, M.H., Lo, J.F., Kuo, C.H., Lin, J.A., Lin, Y.M., Chen, L.M., Tsai, F.J., Tsai, C.H., Huang, C.Y., Tang, C.H., Endothelin-1 promotes MMP-13 production and migration in human chondrosarcoma cells through FAK/PI3K/Akt/mTOR pathways. J. Cell. Physiol. 227 (2012), 3016–3026.
-
(2012)
J. Cell. Physiol.
, vol.227
, pp. 3016-3026
-
-
Wu, M.H.1
Lo, J.F.2
Kuo, C.H.3
Lin, J.A.4
Lin, Y.M.5
Chen, L.M.6
Tsai, F.J.7
Tsai, C.H.8
Huang, C.Y.9
Tang, C.H.10
-
6
-
-
84856110154
-
Endothelin-1 stimulates colon cancer adjacent fibroblasts
-
[6] Knowles, J.P., Shi-Wen, X., Haque, S.U., Bhalla, A., Dashwood, M.R., Yang, S., Taylor, I., Winslet, M.C., Abraham, D.J., Loizidou, M., Endothelin-1 stimulates colon cancer adjacent fibroblasts. Int. J. Cancer 130 (2012), 1264–1272.
-
(2012)
Int. J. Cancer
, vol.130
, pp. 1264-1272
-
-
Knowles, J.P.1
Shi-Wen, X.2
Haque, S.U.3
Bhalla, A.4
Dashwood, M.R.5
Yang, S.6
Taylor, I.7
Winslet, M.C.8
Abraham, D.J.9
Loizidou, M.10
-
7
-
-
82655189563
-
Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes
-
[7] Ha, N.H., Nair, V.S., Reddy, D.N., Mudvari, P., Ohshiro, K., Ghanta, K.S., Pakala, S.B., Li, D.Q., Costa, L., Lipton, A., Badwe, R.A., Fuqua, S., Wallon, M., Prendergast, G.C., Kumar, R., Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes. Cancer Res. 71 (2011), 7259–7269.
-
(2011)
Cancer Res.
, vol.71
, pp. 7259-7269
-
-
Ha, N.H.1
Nair, V.S.2
Reddy, D.N.3
Mudvari, P.4
Ohshiro, K.5
Ghanta, K.S.6
Pakala, S.B.7
Li, D.Q.8
Costa, L.9
Lipton, A.10
Badwe, R.A.11
Fuqua, S.12
Wallon, M.13
Prendergast, G.C.14
Kumar, R.15
-
8
-
-
84867579283
-
Endothelin-1 stimulates oral fibroblasts to promote oral cancer invasion
-
[8] Hinsley, E.E., Kumar, S., Hunter, K.D., Whawell, S.A., Lambert, D.W., Endothelin-1 stimulates oral fibroblasts to promote oral cancer invasion. Life Sci. 91 (2012), 557–561.
-
(2012)
Life Sci.
, vol.91
, pp. 557-561
-
-
Hinsley, E.E.1
Kumar, S.2
Hunter, K.D.3
Whawell, S.A.4
Lambert, D.W.5
-
9
-
-
84898666129
-
The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor
-
[9] Spinella, F., Caprara, V., Cianfrocca, R., Rosanò, L., Di Castro, V., Garrafa, E., Natali, P.G., Bagnato, A., The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor. Carcinogenesis 35 (2014), 840–848.
-
(2014)
Carcinogenesis
, vol.35
, pp. 840-848
-
-
Spinella, F.1
Caprara, V.2
Cianfrocca, R.3
Rosanò, L.4
Di Castro, V.5
Garrafa, E.6
Natali, P.G.7
Bagnato, A.8
-
10
-
-
84903879222
-
Exogenous endothelin-1 induces cell migration and matrix metalloproteinaseexpression in U251 human glioblastoma multiforme
-
[10] Hsieh, W.T., Yeh, W.L., Cheng, R.Y., Lin, C., Tsai, C.F., Huang, B.R., Wu, C.Y., Lin, H.Y., Huang, S.S., Lu, D.Y., Exogenous endothelin-1 induces cell migration and matrix metalloproteinaseexpression in U251 human glioblastoma multiforme. J. Neuro-Oncol. 118 (2014), 257–269.
-
(2014)
J. Neuro-Oncol.
, vol.118
, pp. 257-269
-
-
Hsieh, W.T.1
Yeh, W.L.2
Cheng, R.Y.3
Lin, C.4
Tsai, C.F.5
Huang, B.R.6
Wu, C.Y.7
Lin, H.Y.8
Huang, S.S.9
Lu, D.Y.10
-
11
-
-
84907638077
-
Endothelin-1/endothelin A receptor-mediated biased signaling is a new player in modulating human ovarian cancer cell tumorigenesis
-
[11] Teoh, J.P., Park, K.M., Wang, Y., Hu, Q., Kim, S., Wu, G., Huang, S., Maihle, N., Kim, I.M., Endothelin-1/endothelin A receptor-mediated biased signaling is a new player in modulating human ovarian cancer cell tumorigenesis. Cell. Signal. 26 (2014), 2885–2895.
-
(2014)
Cell. Signal.
, vol.26
, pp. 2885-2895
-
-
Teoh, J.P.1
Park, K.M.2
Wang, Y.3
Hu, Q.4
Kim, S.5
Wu, G.6
Huang, S.7
Maihle, N.8
Kim, I.M.9
-
12
-
-
80052359992
-
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
-
[12] Shukla, A.K., Xiao, K., Lefkowitz, R.J., Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling. Trends Biochem. Sci. 36 (2011), 457–469.
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 457-469
-
-
Shukla, A.K.1
Xiao, K.2
Lefkowitz, R.J.3
-
13
-
-
62449145673
-
β-Arrestin links endothelin A receptor to β-catenin signaling to induce ovarian cancer cell invasion and metastasis
-
[13] Rosanò, L., Cianfrocca, R., Masi, S., Spinella, F., Di Castro, V., Birocci, A., Salvati, E., Nicotra, M.R., Natali, P.G., Bagnato, A., β-Arrestin links endothelin A receptor to β-catenin signaling to induce ovarian cancer cell invasion and metastasis. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 2806–2811.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 2806-2811
-
-
Rosanò, L.1
Cianfrocca, R.2
Masi, S.3
Spinella, F.4
Di Castro, V.5
Birocci, A.6
Salvati, E.7
Nicotra, M.R.8
Natali, P.G.9
Bagnato, A.10
-
14
-
-
84886100276
-
β-Arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling
-
[14] Rosanò, L., Cianfrocca, R., Tocci, P., Spinella, F., Di Castro, V., Spadaro, F., Salvati, E., Biroccio, A.M., Natali, P.G., Bagnato, A., β-Arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling. Oncogene 32 (2013), 5066–5077.
-
(2013)
Oncogene
, vol.32
, pp. 5066-5077
-
-
Rosanò, L.1
Cianfrocca, R.2
Tocci, P.3
Spinella, F.4
Di Castro, V.5
Spadaro, F.6
Salvati, E.7
Biroccio, A.M.8
Natali, P.G.9
Bagnato, A.10
-
15
-
-
84883164592
-
Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells
-
[15] Spinella, F., Caprara, V., Di Castro, V., Rosanò, L., Cianfrocca, R., Natali, P.G., Bagnato, A., Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells. J. Mol. Med. 91 (2013), 395–405.
-
(2013)
J. Mol. Med.
, vol.91
, pp. 395-405
-
-
Spinella, F.1
Caprara, V.2
Di Castro, V.3
Rosanò, L.4
Cianfrocca, R.5
Natali, P.G.6
Bagnato, A.7
-
16
-
-
84918530212
-
Endothelin A receptor/β-arrestin signaling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy
-
[16] Rosanò, L., Cianfrocca, R., Tocci, P., Spinella, F., Di Castro, V., Caprara, V., Semprucci, E., Ferrandina, G., Natali, P.G., Bagnato, A., Endothelin A receptor/β-arrestin signaling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy. Cancer Res. 74 (2014), 7453–7464.
-
(2014)
Cancer Res.
, vol.74
, pp. 7453-7464
-
-
Rosanò, L.1
Cianfrocca, R.2
Tocci, P.3
Spinella, F.4
Di Castro, V.5
Caprara, V.6
Semprucci, E.7
Ferrandina, G.8
Natali, P.G.9
Bagnato, A.10
-
17
-
-
80054782210
-
β-Arrestin-dependent actin reorganization: bringing the right players together at the leading edge
-
[17] Min, J., Defea, K.A., β-Arrestin-dependent actin reorganization: bringing the right players together at the leading edge. Mol. Pharmacol. 80 (2011), 760–768.
-
(2011)
Mol. Pharmacol.
, vol.80
, pp. 760-768
-
-
Min, J.1
Defea, K.A.2
-
18
-
-
84879084333
-
Arrestins in actin reorganization and cell migration
-
[18] Defea, K.A., Arrestins in actin reorganization and cell migration. Prog. Mol. Biol. Transl. Sci. 118 (2013), 205–222.
-
(2013)
Prog. Mol. Biol. Transl. Sci.
, vol.118
, pp. 205-222
-
-
Defea, K.A.1
-
19
-
-
68549126922
-
The cytoskeleton and cancer
-
[19] Hall, A., The cytoskeleton and cancer. Cancer Metastasis Rev. 28 (2009), 5–14.
-
(2009)
Cancer Metastasis Rev.
, vol.28
, pp. 5-14
-
-
Hall, A.1
-
20
-
-
79952352658
-
Dynamics of the Rho-family small GTPases in actin regulation and motility
-
[20] Spiering, D., Hodgson, L., Dynamics of the Rho-family small GTPases in actin regulation and motility. Cell Adhes. Migr. 2 (2011), 1–11.
-
(2011)
Cell Adhes. Migr.
, vol.2
, pp. 1-11
-
-
Spiering, D.1
Hodgson, L.2
-
21
-
-
50149083752
-
-
Mammalian Rho GTPases: new insights into their functions from in vivo studies, Nat. Rev. Mol. Cell Biol. 9
-
[21] S.J. Heasman, A.J. Ridley, Mammalian Rho GTPases: new insights into their functions from in vivo studies, Nat. Rev. Mol. Cell Biol. 9 (2008) 690–701.
-
(2008)
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
22
-
-
84884168966
-
RhoA, RhoB and RhoC have different roles in cancer cell migration
-
[22] Ridley, A.J., RhoA, RhoB and RhoC have different roles in cancer cell migration. J. Microsc. 251 (2013), 242–249.
-
(2013)
J. Microsc.
, vol.251
, pp. 242-249
-
-
Ridley, A.J.1
-
24
-
-
79954627096
-
Acquisition of chemoresistance and EMT phenotypeislinked with activation of the endothelin A receptorpathway in ovarian carcinoma cells
-
[24] Rosanò, L., Cianfrocca, R., Spinella, F., Di Castro, V., Nicotra, M.R., Lucidi, A., Ferrandina, G., Natali, P.G., Bagnato, A., Acquisition of chemoresistance and EMT phenotypeislinked with activation of the endothelin A receptorpathway in ovarian carcinoma cells. Clin. Cancer Res. 17 (2011), 2350–2360.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 2350-2360
-
-
Rosanò, L.1
Cianfrocca, R.2
Spinella, F.3
Di Castro, V.4
Nicotra, M.R.5
Lucidi, A.6
Ferrandina, G.7
Natali, P.G.8
Bagnato, A.9
-
25
-
-
0029786313
-
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
-
[25] Amano, M., Ito, M., Kimura, K., Fukata, Y., Kihara, K., Nakano, T., Matsuura, Y., Kaibuchi, K., Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J. Biol. Chem. 271 (1996), 20246–202499.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20246-202499
-
-
Amano, M.1
Ito, M.2
Kimura, K.3
Fukata, Y.4
Kihara, K.5
Nakano, T.6
Matsuura, Y.7
Kaibuchi, K.8
-
26
-
-
9444242736
-
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
-
[26] Kimura, K., Ito, M., Amano, M., Kihara, K., Fukata, Y., Nakafufu, M., Yamamori, B., Feng, J., Nakano, T., Okawa, K., Iwamatsu, A., Kaibuchi, K., Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273 (1996), 245–248.
-
(1996)
Science
, vol.273
, pp. 245-248
-
-
Kimura, K.1
Ito, M.2
Amano, M.3
Kihara, K.4
Fukata, Y.5
Nakafufu, M.6
Yamamori, B.7
Feng, J.8
Nakano, T.9
Okawa, K.10
Iwamatsu, A.11
Kaibuchi, K.12
-
27
-
-
0037128213
-
Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold
-
[27] Cho, S.Y., Klemke, R.L., Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold. J. Cell Biol. 156 (2002), 725–736.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 725-736
-
-
Cho, S.Y.1
Klemke, R.L.2
-
28
-
-
79959774261
-
Recent progress in the diagnosis and treatment of ovarian cancer
-
[28] Jelovac, D., Armstrong, K.D.K., Recent progress in the diagnosis and treatment of ovarian cancer. CA Cancer J. Clinic. 61 (2011), 183–203.
-
(2011)
CA Cancer J. Clinic.
, vol.61
, pp. 183-203
-
-
Jelovac, D.1
Armstrong, K.D.K.2
-
29
-
-
84940173841
-
G protein-coupled receptor and RhoA-stimulated transcriptional responses: links to inflammation, differentiation, and cell proliferation
-
[29] Yu, O.M., Brown, J.H., G protein-coupled receptor and RhoA-stimulated transcriptional responses: links to inflammation, differentiation, and cell proliferation. Mol. Pharmacol. 88 (2015), 171–180.
-
(2015)
Mol. Pharmacol.
, vol.88
, pp. 171-180
-
-
Yu, O.M.1
Brown, J.H.2
-
30
-
-
69249208550
-
12/13-coupled receptors
-
12/13-coupled receptors. Br. J.Pharmacol. 158 (2009), 41–49.
-
(2009)
Br. J.Pharmacol.
, vol.158
, pp. 41-49
-
-
Siehler, S.1
-
31
-
-
34447649922
-
Beta-arrestin-biased ligands at seven-transmembrane receptors
-
[31] Violin, J.D., Lefkowitz, R.J., Beta-arrestin-biased ligands at seven-transmembrane receptors. Trends Pharmacol. Sci. 28 (2007), 416–422.
-
(2007)
Trends Pharmacol. Sci.
, vol.28
, pp. 416-422
-
-
Violin, J.D.1
Lefkowitz, R.J.2
-
32
-
-
14844338481
-
-
Beta-arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. J Biol Chem. Mar 4;
-
[32] W.G. Barnes, E. Reiter, J.D. Violin, X.R. Ren, G. Milligan, R.J. Lefkowitz, Beta-arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. J Biol Chem. 2005 Mar 4;280(9):8041–50.
-
(2005)
, vol.280
, Issue.9
, pp. 8041-8050
-
-
Barnes, W.G.1
Reiter, E.2
Violin, J.D.3
Ren, X.R.4
Milligan, G.5
Lefkowitz, R.J.6
-
33
-
-
84861740318
-
-
Acute activation of β2-adrenergic receptor regulates focal adhesions through βArrestin2- and p115RhoGEF protein-mediated activation of RhoA. J Biol Chem. 287
-
[33] X. Ma, Y. Zhao, Y. Daaka, Z. Nie, Acute activation of β2-adrenergic receptor regulates focal adhesions through βArrestin2- and p115RhoGEF protein-mediated activation of RhoA. J Biol Chem. 287 (2012) 18925–18936.
-
(2012)
, pp. 18925-18936
-
-
Ma, X.1
Zhao, Y.2
Daaka, Y.3
Nie, Z.4
-
34
-
-
79952265050
-
β-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II Type 1A receptor stimulation
-
[34] Anthony, D.F., Sin, Y.Y., Vadrevu, S., Advant, N., Day, J.P., Byrne, A.M., Lynch, M.J., Milligan, G., Houslay, M.D., Baillie, G.S., β-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II Type 1A receptor stimulation. Mol. Cell. Biol. 31 (2011), 1066–1075.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 1066-1075
-
-
Anthony, D.F.1
Sin, Y.Y.2
Vadrevu, S.3
Advant, N.4
Day, J.P.5
Byrne, A.M.6
Lynch, M.J.7
Milligan, G.8
Houslay, M.D.9
Baillie, G.S.10
-
35
-
-
18544379729
-
Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization
-
[35] Bhattacharya, M., Anborgh, P.H., Babwah, A.V., Dale, L.B., Dobransky, T., Benovic, J.L., Feldman, R.D., Verdi, J.M., Rylett, R.J., Ferguson, S.S., Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization. Nat. Cell Biol. 4 (2002), 547–555.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 547-555
-
-
Bhattacharya, M.1
Anborgh, P.H.2
Babwah, A.V.3
Dale, L.B.4
Dobransky, T.5
Benovic, J.L.6
Feldman, R.D.7
Verdi, J.M.8
Rylett, R.J.9
Ferguson, S.S.10
-
36
-
-
84873640501
-
Pseudopodial and β-arrestin-interacting proteomes from migrating breast cancer cells upon PAR2 activation
-
[36] Parisis, N., Metodieva, G., Metodiev, M.V., Pseudopodial and β-arrestin-interacting proteomes from migrating breast cancer cells upon PAR2 activation. J. Proteomics. 80 (2013), 91–106.
-
(2013)
J. Proteomics.
, vol.80
, pp. 91-106
-
-
Parisis, N.1
Metodieva, G.2
Metodiev, M.V.3
|