β-Arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial-mesenchymal transition

Cancer Research

Volumn 75, Issue 6, 2015, Pages 1009-1020

  Pillai, Smitha ^a   Trevino, Jose ^b   Rawal, Bhupendra ^c   Singh, Sandeep ^d   Kovacs, Michelle ^a   Li, Xueli ^a   Schell, Michael ^a   Haura, Eric ^a   Bepler, Gerold ^e   Chellappan, Srikumar ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

^d NATIONAL INSTITUTE OF BIOMEDICAL GENOMICS   (India)

^e KARMANOS CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN 1; FIBRONECTIN; NICOTINE; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR ZEB1; TRANSCRIPTION FACTOR ZEB2; UNCLASSIFIED DRUG; VIMENTIN; BETA ARRESTIN; E2F1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; NICOTINIC RECEPTOR; RETINA S ANTIGEN; RETINOBLASTOMA PROTEIN; ZEB1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG METASTASIS; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TIGHT JUNCTION; TUMOR GROWTH; ANIMAL; DRUG EFFECTS; GENETICS; LUNG TUMOR; METASTASIS; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; ARRESTINS; CELL LINE, TUMOR; E2F1 TRANSCRIPTION FACTOR; EPITHELIAL-MESENCHYMAL TRANSITION; FIBRONECTINS; HOMEODOMAIN PROTEINS; HUMANS; LUNG NEOPLASMS; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NICOTINE; RECEPTORS, NICOTINIC; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION; TIGHT JUNCTIONS; TRANSCRIPTION FACTORS; VIMENTIN;

EID: 84935867705     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-0681     Document Type: Article

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