ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks

Nature Neuroscience

Volumn 19, Issue 9, 2016, Pages 1256-1267

  Ho, Ritchie ^a   Sances, Samuel ^a   Gowing, Genevieve ^a   Amoroso, Mackenzie Weygandt ^b   O'Rourke, Jacqueline G ^a   Sahabian, Anais ^a   Wichterle, Hynek ^c,d   Baloh, Robert H ^a   Sareen, Dhruv ^a   Svendsen, Clive N ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b HARVARD UNIVERSITY   (United States)

^c Project ALS/Jenifer Estess Laboratory for Stem Cell Research   (United States)

^d NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTOME;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL AGING; CELL MATURATION; COMPARATIVE STUDY; CONTROLLED STUDY; FETUS; GENE ACTIVATION; GENE DISRUPTION; GENE EXPRESSION; GENE REPRESSION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; INDUCED PLURIPOTENT STEM CELL; NERVOUS TISSUE; PRIORITY JOURNAL; SPINAL CORD MOTONEURON; TRANSCRIPTOMICS; AGING; CYTOLOGY; GENE REGULATORY NETWORK; GENETICS; METABOLISM; MOTONEURON; NERVOUS SYSTEM DEVELOPMENT; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGING; AMYOTROPHIC LATERAL SCLEROSIS; GENE EXPRESSION; GENE REGULATORY NETWORKS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MOTOR NEURONS; NEUROGENESIS;

EID: 84978655820     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.4345     Document Type: Article

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