Specific electron transport chain abnormalities in amyotrophic lateral sclerosis

Journal of Neurology

Volumn 256, Issue 5, 2009, Pages 774-782

  Lin, Jerry ^a   Diamanduros, Andrew ^b   Chowdhury, Soheli A ^a   Scelsa, Stephen ^c   Latov, Norman ^d   Sadiq, Saud A ^a  

^a Multiple Sclerosis Research Center of New York Inc   (United States)

^b GEORGIA SOUTHERN UNIVERSITY   (United States)

^c BETH ISRAEL MEDICAL CENTER   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

ALS; Mitochondrial disorders

Indexed keywords

BETA ACTIN; COMPLEMENTARY DNA; CYTOCHROME C1; FLAVIN MONONUCLEOTIDE ADENYLYLTRANSFERASE; FLAVINE ADENINE NUCLEOTIDE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A ANTIBODY; MESSENGER RNA; MONOCLONAL ANTIBODY; RIBOFLAVIN KINASE; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL FUNCTION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA LIBRARY; DNA SEQUENCE; DOWN REGULATION; ELECTRON TRANSPORT; GENE EXPRESSION PROFILING; GENETIC SCREENING; HUMAN; HUMAN CELL; MITOCHONDRION; MOTONEURON; NEUROBLASTOMA; NEUROPATHOLOGY; NUCLEOTIDE SEQUENCE; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; QUANTITATIVE GENETICS; RESPIRATORY CHAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CATTLE; CELL LINE, TUMOR; CELL RESPIRATION; CELLS, CULTURED; CYTOCHROMES C1; DOWN-REGULATION; ENERGY METABOLISM; HUMANS; IMMUNOGLOBULIN A; MITOCHONDRIAL DISEASES; MOTOR NEURONS; NUCLEOTIDYLTRANSFERASES; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PARAPROTEINEMIAS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SUCCINATE DEHYDROGENASE;

EID: 67349099922     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-009-5015-8     Document Type: Article

References (30)

1. Apostolski S, Thomas FP, Sadiq SA, Suder F, Cadet JL, Latov N, Hays AP, Mena MA, DeYebenes JG (1990) IgA monoclonal antibody in ALS inhibits proliferation of human neuroblastoma cells. In: Neurology, p 184 Abstr
2. SH Appel JI Engelhardt JS Henkel L Siklos DR Beers AA Yen EP Simpson Y Luo G Carrum HE Heslop MK Brenner U Popat 2008 Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis Neurology 71 1326 1334
3. M Barile S Passarella A Bertoldi E Quagliariello 1993 Flavin adenine dinucleotide synthesis in isolated rat liver mitochondria caused by imported flavin mononucleotide Arch Biochem Biophys 305 442 447 (Pubitemid 23282929)
4. E Beghi A Chio M Inghilleri L Mazzini A Micheli G Mora M Poloni R Riva L Serlenga D Testa P Tonali 2000 A randomized controlled trial of recombinant interferon beta-1a in ALS. Italian Amyotrophic Lateral Sclerosis Study Group Neurology 54 469 474
5. GM Borthwick MA Johnson PG Ince PJ Shaw DM Turnbull 1999 Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death Ann Neurol 46 787 790 (Pubitemid 29518143)
6. C Brizio M Galluccio R Wait EM Torchetti V Bafunno R Accardi E Gianazza C Indiveri M Barile 2006 Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase Biochem Biophys Res Commun 344 1008 1016 (Pubitemid 44304386)
7. GP Comi A Bordoni S Salani L Franceschina M Sciacco A Prelle F Fortunato M Zeviani L Napoli N Bresolin M Moggio CD Ausenda JW Taanman G Scarlato 1998 Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease Ann Neurol 43 110 116 (Pubitemid 28124656)
8. MR Cookson FM Menzies P Manning CJ Eggett DA Figlewicz CJ McNeil PJ Shaw 2002 Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress Amyotroph Lateral Scler Other Motor Neuron Disord 3 75 85
9. C Deluca NO Kaplan 1958 Flavin adenine dinucleotide synthesis in animal tissues Biochim Biophys Acta 30 6 11
10. DB Drachman V Chaudhry D Cornblath RW Kuncl A Pestronk L Clawson ED Mellits S Quaskey T Quinn A Calkins 1994 Trial of immunosuppression in amyotrophic lateral sclerosis using total lymphoid irradiation Ann Neurol 35 142 150 (Pubitemid 24050149)
11. JI Engelhardt SH Appel JM Killian 1989 Experimental autoimmune motoneuron disease Ann Neurol 26 368 376 (Pubitemid 19230306)
12. S Hamajima S Ono H Hirano K Obara 1979 Induction of the FAD synthetase system in rat liver by phenobarbital administration Int J Vitam Nutr Res 49 59 63 (Pubitemid 9176576)
13. AP Hays A Roxas SA Sadiq H Vallejos V D'Agati FP Thomas R Torres WH Sherman D Bailey-Braxton AG Hays 1990 A monoclonal IgA in a patient with amyotrophic lateral sclerosis reacts with neurofilaments and surface antigen on neuroblastoma cells J Neuropathol Exp Neurol 49 383 398 (Pubitemid 20207799)
14. J Kong Z Xu 1998 Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1 J Neurosci 18 3241 3250 (Pubitemid 28186017)
15. N Latov 1990 Neuropathic syndromes associated with monoclonal gammopathies Res Publ Assoc Res Nerv Ment Dis 68 221 232
16. G Manfredi Z Xu 2005 Mitochondrial dysfunction and its role in motor neuron degeneration in ALS Mitochondrion 5 77 87 (Pubitemid 40485768)
17. LJ Martin 2006 Mitochondriopathy in Parkinson disease and amyotrophic lateral sclerosis J Neuropathol Exp Neurol 65 1103 1110
18. LJ Martin Z Liu K Chen AC Price Y Pan JA Swaby WC Golden 2007 Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death J Comp Neurol 500 20 46
19. BM Morrison JH Morrison 1999 Amyotrophic lateral sclerosis associated with mutations in superoxide dismutase: a putative mechanism of degeneration Brain Res Brain Res Rev 29 121 135 (Pubitemid 29016082)
20. LP Rowland 1991 Ten central themes in a decade of ALS research Adv Neurol 56 3 23
21. Rowland LP (ed), Merritt HH (2005) Merritt's neurology. Lippincott Williams & Wilkins, Philadelphia
22. SA Sadiq N Latov 1991 Monoclonal gammopathy and motor neuron disease Adv Neurol 56 413 420
23. SA Sadiq FP Thomas K Kilidireas S Protopsaltis AP Hays KW Lee SN Romas N Kumar L van den Berg M Santoro 1990 The spectrum of neurologic disease associated with anti-GM1 antibodies Neurology 40 1067 1072 (Pubitemid 20213973)
24. SA Sadiq LH van den Berg FP Thomas K Kilidireas AP Hays N Latov 1991 Human monoclonal antineurofilament antibody cross-reacts with a neuronal surface protein J Neurosci Res 29 319 325
25. ME Shy LP Rowland T Smith W Trojaborg N Latov W Sherman MA Pesce RE Lovelace EF Osserman 1986 Motor neuron disease and plasma cell dyscrasia Neurology 36 1429 1436 (Pubitemid 17175764)
26. T Tanridag T Coskun C Hurdag S Arbak S Aktan B Yegen 1999 Motor neuron degeneration due to aluminium deposition in the spinal cord: a light microscopical study Acta Histochem 101 193 201 (Pubitemid 29211262)
27. S Vielhaber D Kunz K Winkler FR Wiedemann E Kirches H Feistner HJ Heinze CE Elger W Schubert WS Kunz 2000 Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis Brain 123 Pt 7 1339 1348 (Pubitemid 30420935)
28. C Vijayvergiya MF Beal J Buck G Manfredi 2005 Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice J Neurosci 25 2463 2470 (Pubitemid 40365156)
29. NK Wong MJ Strong 1998 Nitric oxide synthase expression in cervical spinal cord in sporadic amyotrophic lateral sclerosis Eur J Cell Biol 77 338 343 (Pubitemid 29017167)
30. DS Younger LP Rowland N Latov W Sherman M Pesce DJ Lange W Trojaborg JR Miller RE Lovelace AP Hays 1990 Motor neuron disease and amyotrophic lateral sclerosis: relation of high CSF protein content to paraproteinemia and clinical syndromes Neurology 40 595 599 (Pubitemid 20139083)